Click here to switch to the map view.

The map label for this gene is atpD2

Identifier: 156977318

GI number: 156977318

Start: 1266188

End: 1267573

Strand: Reverse

Name: atpD2

Synonym: VIBHAR_06104

Alternate gene names: 156977318

Gene position: 1267573-1266188 (Counterclockwise)

Preceding gene: 156977319

Following gene: 156977317

Centisome position: 57.51

GC content: 49.35

Gene sequence:

>1386_bases
ATGAGTATTGGCAAAATCGTCAAAGTCATCGGTGCGGTGGTCGACGTCGAGTTCGAACAAGGCAAAGGCCCGAAAGTTTA
CGATGCACTGAAAATCAACGATGGCAGCGATGGCTCACTGATGTTGGAAGTCCAGCAACAGTTGGGCGGCGGTGTGGTTC
GCTGTATCGCAATGGGTTCTTCGGATGGCCTTAAACGTGGCCTAGAAGTGGAATCTACGGGCAACCCAATCACGGTACCT
GTGGGTGAAGAAACCCTAGGTCGTATCATGAACGTGTTGGGTCATCCAATCGATGAATGTGGTCCAATCGGTGAGCAAGT
GTCTTACGAGATCCACCGTGATGCACCAAGCTACGAAGAGCAATCTAACAGCACCGCGCTACTAGAGACGGGCGTTAAAG
TCATTGACTTGATTTGTCCGTTTGCGAAGGGCGGTAAGATCGGTCTGTTCGGTGGTGCGGGTGTAGGTAAGACGGTAAAC
ATGATGGAGCTTATCAATAACATTGCTAAAGCTCACTCAGGTTTGTCGGTATTTACCGGTGTAGGTGAACGTACTCGTGA
GGGTAACGACTTCTACTACGAAATGAAGGAAGCGGGCGTTCTCGACAAAGTAGCCATGGTTTACGGTCAGATGAACGAGC
CACCGGGTAACCGTCTACGTGTTGCGCTAACAGGCTTGACCATCGCAGAACGTTTCCGTGATGAAGGTCGTGACGTACTG
TTGTTCGTGGATAACATTTACCGTTACACATTGGCAGGTACTGAGGTGTCGGCATTGCTTGGTCGTATGCCATCTGCGGT
AGGTTACCAACCAACACTGGCAGAAGAGATGGGTGTGCTTCAAGAGCGTATCACGTCGACTAAGAATGGTTCTATCACGT
CTATCCAAGCGGTTTACGTACCAGCGGATGACTTGACCGACCCATCGCCAGCAACTACTTTTGCGCACTTGGATGCGACG
GTCGTTCTGTCTCGTAACATCGCTGCTTTGGGTCTGTACCCAGCGATTGACCCATTGGATTCAACATCCCGTCAGCTTGA
TCCTCAAGTGGTTGGTCAAGAGCATTACGATGTAGCGCGTAAAGTTCAGCAAACGCTACAACGTTACAAAGAGCTAAAAG
ACATCATTGCCATCCTAGGTATGGATGAACTGTCTGAAGAAGATAAGCGCTTGGTATCTCGTGCTCGTAAAGTTGAACGT
TTCCTAACTCAGCCTTACCACGTAGCTGAAGTGTTTACGGGTCAACCGGGTGTATTCGTTCCACTAAAAGACACCATTGC
AGGCTTTAAAGCGCTGCTTGATGGTCAGTACGACGACATCCCAGAGCAGGCATTTATGTACTGCGGCAACATCGACGAAG
TGCTTGAAAAAGCGAAAAAACTGTAA

Upstream 100 bases:

>100_bases
TGGTTTACAACAAAGCGCGTCAAGCGGCGATCACTCAAGAGTTGAGTGAAATTGTATCCGGCGCACAAGCGGTTTAGAGA
GAGAATTTGAGGTTTAAATT

Downstream 100 bases:

>100_bases
AGCGCGGGAGGCAATATGGCCATAGCGGTTTCACAAAATACGTTTCAACTGAATGTGGTAAGTGCAGAGGGCACACTTTA
CTCAGGTCCAGCGCACGCTA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 2; F-ATPase subunit beta 2

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSIGKIVKVIGAVVDVEFEQGKGPKVYDALKINDGSDGSLMLEVQQQLGGGVVRCIAMGSSDGLKRGLEVESTGNPITVP
VGEETLGRIMNVLGHPIDECGPIGEQVSYEIHRDAPSYEEQSNSTALLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVN
MMELINNIAKAHSGLSVFTGVGERTREGNDFYYEMKEAGVLDKVAMVYGQMNEPPGNRLRVALTGLTIAERFRDEGRDVL
LFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKNGSITSIQAVYVPADDLTDPSPATTFAHLDAT
VVLSRNIAALGLYPAIDPLDSTSRQLDPQVVGQEHYDVARKVQQTLQRYKELKDIIAILGMDELSEEDKRLVSRARKVER
FLTQPYHVAEVFTGQPGVFVPLKDTIAGFKALLDGQYDDIPEQAFMYCGNIDEVLEKAKKL

Sequences:

>Translated_461_residues
MSIGKIVKVIGAVVDVEFEQGKGPKVYDALKINDGSDGSLMLEVQQQLGGGVVRCIAMGSSDGLKRGLEVESTGNPITVP
VGEETLGRIMNVLGHPIDECGPIGEQVSYEIHRDAPSYEEQSNSTALLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVN
MMELINNIAKAHSGLSVFTGVGERTREGNDFYYEMKEAGVLDKVAMVYGQMNEPPGNRLRVALTGLTIAERFRDEGRDVL
LFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKNGSITSIQAVYVPADDLTDPSPATTFAHLDAT
VVLSRNIAALGLYPAIDPLDSTSRQLDPQVVGQEHYDVARKVQQTLQRYKELKDIIAILGMDELSEEDKRLVSRARKVER
FLTQPYHVAEVFTGQPGVFVPLKDTIAGFKALLDGQYDDIPEQAFMYCGNIDEVLEKAKKL
>Mature_460_residues
SIGKIVKVIGAVVDVEFEQGKGPKVYDALKINDGSDGSLMLEVQQQLGGGVVRCIAMGSSDGLKRGLEVESTGNPITVPV
GEETLGRIMNVLGHPIDECGPIGEQVSYEIHRDAPSYEEQSNSTALLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVNM
MELINNIAKAHSGLSVFTGVGERTREGNDFYYEMKEAGVLDKVAMVYGQMNEPPGNRLRVALTGLTIAERFRDEGRDVLL
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKNGSITSIQAVYVPADDLTDPSPATTFAHLDATV
VLSRNIAALGLYPAIDPLDSTSRQLDPQVVGQEHYDVARKVQQTLQRYKELKDIIAILGMDELSEEDKRLVSRARKVERF
LTQPYHVAEVFTGQPGVFVPLKDTIAGFKALLDGQYDDIPEQAFMYCGNIDEVLEKAKKL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=467, Percent_Identity=67.0235546038544, Blast_Score=628, Evalue=1e-180,
Organism=Homo sapiens, GI19913428, Length=415, Percent_Identity=26.5060240963855, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913424, Length=306, Percent_Identity=27.7777777777778, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI19913426, Length=374, Percent_Identity=24.8663101604278, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI50345984, Length=363, Percent_Identity=24.5179063360882, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4757810, Length=363, Percent_Identity=24.5179063360882, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1790170, Length=461, Percent_Identity=78.3080260303688, Blast_Score=743, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=325, Percent_Identity=30.4615384615385, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1790172, Length=410, Percent_Identity=24.8780487804878, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=465, Percent_Identity=66.4516129032258, Blast_Score=619, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI17565854, Length=356, Percent_Identity=26.685393258427, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=406, Percent_Identity=25.615763546798, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988080, Length=393, Percent_Identity=24.9363867684478, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=393, Percent_Identity=24.9363867684478, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=351, Percent_Identity=25.6410256410256, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71988074, Length=354, Percent_Identity=24.2937853107345, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=69.2139737991266, Blast_Score=642, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=354, Percent_Identity=27.1186440677966, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319370, Length=368, Percent_Identity=25.8152173913043, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=284, Percent_Identity=24.2957746478873, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24638766, Length=465, Percent_Identity=66.6666666666667, Blast_Score=616, Evalue=1e-176,
Organism=Drosophila melanogaster, GI28574560, Length=465, Percent_Identity=63.8709677419355, Blast_Score=592, Evalue=1e-169,
Organism=Drosophila melanogaster, GI20129479, Length=347, Percent_Identity=25.9365994236311, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281361666, Length=412, Percent_Identity=25, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646341, Length=412, Percent_Identity=25, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136796, Length=412, Percent_Identity=25, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24583992, Length=305, Percent_Identity=28.5245901639344, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24583988, Length=354, Percent_Identity=26.5536723163842, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583986, Length=354, Percent_Identity=26.5536723163842, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583984, Length=354, Percent_Identity=26.5536723163842, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24658560, Length=378, Percent_Identity=23.015873015873, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=54.9450549450549, Blast_Score=89, Evalue=9e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB2_VIBHB (A7N6Q5)

Other databases:

- EMBL:   CP000790
- RefSeq:   YP_001448224.1
- ProteinModelPortal:   A7N6Q5
- SMR:   A7N6Q5
- STRING:   A7N6Q5
- GeneID:   5556997
- GenomeReviews:   CP000790_GR
- KEGG:   vha:VIBHAR_06104
- NMPDR:   fig|338187.4.peg.3593
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   LTIAERF
- ProtClustDB:   PRK12597
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50063; Mature: 49932

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGKIVKVIGAVVDVEFEQGKGPKVYDALKINDGSDGSLMLEVQQQLGGGVVRCIAMGS
CCHHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCEEEEEHHHHCCCEEEEEEECC
SDGLKRGLEVESTGNPITVPVGEETLGRIMNVLGHPIDECGPIGEQVSYEIHRDAPSYEE
CHHHHCCCEEECCCCEEEEECCHHHHHHHHHHHCCCCHHHCCCCHHHCEEEECCCCCCHH
QSNSTALLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVNMMELINNIAKAHSGLSVFTG
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEECC
VGERTREGNDFYYEMKEAGVLDKVAMVYGQMNEPPGNRLRVALTGLTIAERFRDEGRDVL
CCCCCCCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEE
LFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKNGSITSIQAVYV
EEEECCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
PADDLTDPSPATTFAHLDATVVLSRNIAALGLYPAIDPLDSTSRQLDPQVVGQEHYDVAR
CCCCCCCCCCCCEEHHCCEEEEEECCCCEEECCCCCCCCCCCHHHCCHHHCCCHHHHHHH
KVQQTLQRYKELKDIIAILGMDELSEEDKRLVSRARKVERFLTQPYHVAEVFTGQPGVFV
HHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCEEE
PLKDTIAGFKALLDGQYDDIPEQAFMYCGNIDEVLEKAKKL
EHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
SIGKIVKVIGAVVDVEFEQGKGPKVYDALKINDGSDGSLMLEVQQQLGGGVVRCIAMGS
CHHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCEEEEEHHHHCCCEEEEEEECC
SDGLKRGLEVESTGNPITVPVGEETLGRIMNVLGHPIDECGPIGEQVSYEIHRDAPSYEE
CHHHHCCCEEECCCCEEEEECCHHHHHHHHHHHCCCCHHHCCCCHHHCEEEECCCCCCHH
QSNSTALLETGVKVIDLICPFAKGGKIGLFGGAGVGKTVNMMELINNIAKAHSGLSVFTG
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEECC
VGERTREGNDFYYEMKEAGVLDKVAMVYGQMNEPPGNRLRVALTGLTIAERFRDEGRDVL
CCCCCCCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEE
LFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKNGSITSIQAVYV
EEEECCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
PADDLTDPSPATTFAHLDATVVLSRNIAALGLYPAIDPLDSTSRQLDPQVVGQEHYDVAR
CCCCCCCCCCCCEEHHCCEEEEEECCCCEEECCCCCCCCCCCHHHCCHHHCCCHHHHHHH
KVQQTLQRYKELKDIIAILGMDELSEEDKRLVSRARKVERFLTQPYHVAEVFTGQPGVFV
HHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCEEE
PLKDTIAGFKALLDGQYDDIPEQAFMYCGNIDEVLEKAKKL
EHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA