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The map label for this gene is lysA [H]

Identifier: 156977279

GI number: 156977279

Start: 1237034

End: 1238290

Strand: Reverse

Name: lysA [H]

Synonym: VIBHAR_06065

Alternate gene names: 156977279

Gene position: 1238290-1237034 (Counterclockwise)

Preceding gene: 156977280

Following gene: 156977278

Centisome position: 56.18

GC content: 40.65

Gene sequence:

>1257_bases
ATGTATCAACCGTATAAAAAAGTCACCGACCTTATAAAGTTCTCTCGGGAATATAAGACGCCGAGTATTATTTATAGCGA
AGTGATAATATCAGAACAATGTGCAGCAATTGTTGAACCAATATCGCAATCGCCTATGGAAGGGAGAGTCTTCTTTCCGA
TTAAAGCTTCCTATGAGCCTATAGTGCTAAAGACACTAGTGAATAATAGCATCTCTGGGTTTGAGGTGATGTCATACCAT
GAATTGAAACACATACGTGCGCTGTTCGGATACCAATACCCCTTGATTTTCTCAGGGTTATGCCCGGACGAGTGTACGTT
GCGCTTACTCTGTTTTGAACAAGACATCCTCGTTATTAATTCGTTGAACGACTGTTTTCGCGTAGTTGATCTTTTACAAT
CTAGTACAGATGGATCTCGGATAACATTGTTATTACGGATTTCATTCCCATGTCTTAATTCAGAGATAGGCTATAACGGT
CGAAATAGTAAGTTAGGTATTATTGCATATAGTAATGAAATGTATCGGTGCCTCGAATTATTGGAGCGACATGAAGGTAT
AAATTTGGAAGGGATACATTGTCACCAATTGATTCATGAATCTTCAGCGAGCGAGTATAGAAAGATGATTCATCAGATGG
CTAAACTGATCGATTCAATTGAGTCGTCAACAAGTTTTAAACTAGCTGTGTGCGATATTGGTGGTGGCTTGGAATCTATG
CCAAATATTAAGACCCGTTCGGTTGTAAAACAGATATGTCAAGAGTTTAACGAGATCTTACCTGACAGGAGTTTAATATT
TGAGCCAGGCCGAGCGCTTGTAAATAGCGGAGGGATCTGTGTCACTAAGGTTATTGGTCAACGCGTCAGAACTCAAACAC
ATCATTGCACGGTTGATGTGGGTAGTAATCTTTTAGTGCCGACTTCCAGTAAGCGTTATCATATAATTCACGAGGATATA
ATTAACTCTGAAGCATCACTAAAGGAAGCTTCTTGTGCAGTTAAAGTCACTTTTTCTGATCGGGTATTAAGTCCAGCTAA
CACGATTGAAGATAACGTTATGATGTTATCTCCCCCACAAGTGGGCAGTTTGCTTCTTATTGGTAACGCTGGAGCTTACA
CCTCAGCTCTTGAGCATCAATGGCTTCAGCCACTTCATTCTACATACTTCCTTTCGTCTAGTGGTGATATTGAGACTCTT
TTATCGTCAGAGGATGCACTAGCCGCATGGAAAGGCCGATGGGGAACGGATGTATGA

Upstream 100 bases:

>100_bases
GCTTTACGGGAAGATTTCACACGCGACAAAGCTAAAAGATGGGCTAGTCACTTTGATTATATAAAAGATCAGGTTTTAAA
TTGTTTCCAAGAGAAGAGTA

Downstream 100 bases:

>100_bases
CAAGTATAAACACAACAGTGAAATTAAGATTATTTCAATTGTTTATGGGCGGAACGGCGAGCAACTTAGTGAAGCCTTTT
TTTGCGGCGACGTTAGCACT

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MYQPYKKVTDLIKFSREYKTPSIIYSEVIISEQCAAIVEPISQSPMEGRVFFPIKASYEPIVLKTLVNNSISGFEVMSYH
ELKHIRALFGYQYPLIFSGLCPDECTLRLLCFEQDILVINSLNDCFRVVDLLQSSTDGSRITLLLRISFPCLNSEIGYNG
RNSKLGIIAYSNEMYRCLELLERHEGINLEGIHCHQLIHESSASEYRKMIHQMAKLIDSIESSTSFKLAVCDIGGGLESM
PNIKTRSVVKQICQEFNEILPDRSLIFEPGRALVNSGGICVTKVIGQRVRTQTHHCTVDVGSNLLVPTSSKRYHIIHEDI
INSEASLKEASCAVKVTFSDRVLSPANTIEDNVMMLSPPQVGSLLLIGNAGAYTSALEHQWLQPLHSTYFLSSSGDIETL
LSSEDALAAWKGRWGTDV

Sequences:

>Translated_418_residues
MYQPYKKVTDLIKFSREYKTPSIIYSEVIISEQCAAIVEPISQSPMEGRVFFPIKASYEPIVLKTLVNNSISGFEVMSYH
ELKHIRALFGYQYPLIFSGLCPDECTLRLLCFEQDILVINSLNDCFRVVDLLQSSTDGSRITLLLRISFPCLNSEIGYNG
RNSKLGIIAYSNEMYRCLELLERHEGINLEGIHCHQLIHESSASEYRKMIHQMAKLIDSIESSTSFKLAVCDIGGGLESM
PNIKTRSVVKQICQEFNEILPDRSLIFEPGRALVNSGGICVTKVIGQRVRTQTHHCTVDVGSNLLVPTSSKRYHIIHEDI
INSEASLKEASCAVKVTFSDRVLSPANTIEDNVMMLSPPQVGSLLLIGNAGAYTSALEHQWLQPLHSTYFLSSSGDIETL
LSSEDALAAWKGRWGTDV
>Mature_418_residues
MYQPYKKVTDLIKFSREYKTPSIIYSEVIISEQCAAIVEPISQSPMEGRVFFPIKASYEPIVLKTLVNNSISGFEVMSYH
ELKHIRALFGYQYPLIFSGLCPDECTLRLLCFEQDILVINSLNDCFRVVDLLQSSTDGSRITLLLRISFPCLNSEIGYNG
RNSKLGIIAYSNEMYRCLELLERHEGINLEGIHCHQLIHESSASEYRKMIHQMAKLIDSIESSTSFKLAVCDIGGGLESM
PNIKTRSVVKQICQEFNEILPDRSLIFEPGRALVNSGGICVTKVIGQRVRTQTHHCTVDVGSNLLVPTSSKRYHIIHEDI
INSEASLKEASCAVKVTFSDRVLSPANTIEDNVMMLSPPQVGSLLLIGNAGAYTSALEHQWLQPLHSTYFLSSSGDIETL
LSSEDALAAWKGRWGTDV

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 46708; Mature: 46708

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQPYKKVTDLIKFSREYKTPSIIYSEVIISEQCAAIVEPISQSPMEGRVFFPIKASYEP
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
IVLKTLVNNSISGFEVMSYHELKHIRALFGYQYPLIFSGLCPDECTLRLLCFEQDILVIN
EEHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHEEEEEEEECCEEEEE
SLNDCFRVVDLLQSSTDGSRITLLLRISFPCLNSEIGYNGRNSKLGIIAYSNEMYRCLEL
CHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECHHHHHHHHH
LERHEGINLEGIHCHQLIHESSASEYRKMIHQMAKLIDSIESSTSFKLAVCDIGGGLESM
HHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
PNIKTRSVVKQICQEFNEILPDRSLIFEPGRALVNSGGICVTKVIGQRVRTQTHHCTVDV
CCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCHHHHHHHHHHHCCCCEEEEEC
GSNLLVPTSSKRYHIIHEDIINSEASLKEASCAVKVTFSDRVLSPANTIEDNVMMLSPPQ
CCEEEEECCCCCEEEEHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCC
VGSLLLIGNAGAYTSALEHQWLQPLHSTYFLSSSGDIETLLSSEDALAAWKGRWGTDV
CCCEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MYQPYKKVTDLIKFSREYKTPSIIYSEVIISEQCAAIVEPISQSPMEGRVFFPIKASYEP
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
IVLKTLVNNSISGFEVMSYHELKHIRALFGYQYPLIFSGLCPDECTLRLLCFEQDILVIN
EEHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHEEEEEEEECCEEEEE
SLNDCFRVVDLLQSSTDGSRITLLLRISFPCLNSEIGYNGRNSKLGIIAYSNEMYRCLEL
CHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECHHHHHHHHH
LERHEGINLEGIHCHQLIHESSASEYRKMIHQMAKLIDSIESSTSFKLAVCDIGGGLESM
HHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
PNIKTRSVVKQICQEFNEILPDRSLIFEPGRALVNSGGICVTKVIGQRVRTQTHHCTVDV
CCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCHHHHHHHHHHHCCCCEEEEEC
GSNLLVPTSSKRYHIIHEDIINSEASLKEASCAVKVTFSDRVLSPANTIEDNVMMLSPPQ
CCEEEEECCCCCEEEEHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCC
VGSLLLIGNAGAYTSALEHQWLQPLHSTYFLSSSGDIETLLSSEDALAAWKGRWGTDV
CCCEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]