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The map label for this gene is hlyB [H]

Identifier: 156977150

GI number: 156977150

Start: 1121323

End: 1122765

Strand: Direct

Name: hlyB [H]

Synonym: VIBHAR_05936

Alternate gene names: 156977150

Gene position: 1121323-1122765 (Clockwise)

Preceding gene: 156977146

Following gene: 156977155

Centisome position: 50.88

GC content: 45.81

Gene sequence:

>1443_bases
ATGGAGCGATTAATGAGAGAAGTTGAGTTTAGAACGATAGACAAGCTATTTATTAAAATGTCTATCAACGACAAAATCTG
GGTCATTTTTCTTCTATTCCTAGTGACTCTGACTTCAGTGGCAGGAAGCCGATATTTCAATGATATTCAGCAGTTTGAAG
ACCAGTCTATCCTTACTGTAGAAGCCAAACTTGCGGGTATTATCCAAGCGAAGCCTCAAAACCTGGCGAACCTAAATGGT
GTGGTGAGTACAATTAACGCCGGTGATGCGACGTTCAACAATGGAACGGTAACGGCTTACGCGAAGCTGAATTCCGGTCA
GGCAATCCAACTGACAGAAAACCTTTCACGCCAATTTGAGCAAGCTAAATCTGACGCCTTGACCTCTTTTCTTCTTAGCT
TTCTTTGGGTGGTGCCGTTTGCCCTATTCAATTACTGGGTTGCCACTTTCCTTGGCGGCGCACTTTGGGTGCTTTACACC
ACCACACAAAAGATTGGTGAAGGAGACTTAACCTCTCGTCTTGGTTTCCATCCGGGGCGAGATGAGTTTGGTACGATTGG
CTGTGCGCTCGATAAATCAATGGATACGCTAACTGAATTAGTAAACAGCGTAAAAGACAATGCCAATACAATGAGCGAAA
CTTCTGCCGCGTTCGAACAAGACATGAAGTTGAGTGAAACTCAAATTGCGCATCAATATCAAACTCTGGATTCTGTCGCT
ACAGCAATGGAAGAGATGACGGCGTCAGCAAAAGAGGTGTCGAGTATTTCTCAACAAGCGACACTTCAATCAGACCAAGA
TGCCCAGCAGATTGAACATAGCCGCACTCGCGTCCAAAGCGTCATTTCAGAGATTGAAACCCTTTCAAGTTACATCGAAC
AGGCGTCAACATCAGTAAGCAGTTTGAATGAAAACACGACGCAGATTAATGATGTCATCACGACGATCAACGCCATCTCA
GAGCAAACTAACCTGCTCGCATTAAATGCTGCTATTGAAGCCGCTCGTGCGGGTGAGCAAGGCCGTGGGTTTGCCGTAGT
TGCAGACGAAGTCCGTACCCTTGCAAGCCGTACCCAGCAAGCGACAGTTGAGATCCAAGCCATGATTGAAAAGCTTCAAT
CTGAGAGTCGAAACATTGCATCAATTACTGATCGTACCGTTCAGCAAGCTCAAACCAGTAGCCAATTGATCGATGAAATT
GGAGGGGACGTGACTGCTATCGCTGATTCTGCACGATCTTTGATGGACATGAGTATTCAGATCTCGACGTCAGCAGAAGA
ACAAAGTGCGGTTGCAAATGACATTGCATCTGAGCTGTCAGATATTCGCTCACAATCCAACACCATCCGTGAAGTGGCAC
AGCAATCGACAGTAGGCGTAACCAATTTAACCCACGCTTCTGTTTCACTTGGCGAAGTATTGAAACGCTACCGAACGGCT
TAA

Upstream 100 bases:

>100_bases
AATTTGAAATCAATCAACTGCTCGTTACATATTTTGCTGATTACCATCTCATATTTTGTTTCGATAGTTCTCTAATTTAG
TTCACCCCTTTTCATCTCAA

Downstream 100 bases:

>100_bases
ATACCGTTTCGCCATCAGGTTAGTAGGTTCAAATCGATACAATCTAAGGGATACCAAATGCAAAGGGCTCCGTTTTTGGA
GCCCTTTTTCACTAGGTGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MERLMREVEFRTIDKLFIKMSINDKIWVIFLLFLVTLTSVAGSRYFNDIQQFEDQSILTVEAKLAGIIQAKPQNLANLNG
VVSTINAGDATFNNGTVTAYAKLNSGQAIQLTENLSRQFEQAKSDALTSFLLSFLWVVPFALFNYWVATFLGGALWVLYT
TTQKIGEGDLTSRLGFHPGRDEFGTIGCALDKSMDTLTELVNSVKDNANTMSETSAAFEQDMKLSETQIAHQYQTLDSVA
TAMEEMTASAKEVSSISQQATLQSDQDAQQIEHSRTRVQSVISEIETLSSYIEQASTSVSSLNENTTQINDVITTINAIS
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATVEIQAMIEKLQSESRNIASITDRTVQQAQTSSQLIDEI
GGDVTAIADSARSLMDMSIQISTSAEEQSAVANDIASELSDIRSQSNTIREVAQQSTVGVTNLTHASVSLGEVLKRYRTA

Sequences:

>Translated_480_residues
MERLMREVEFRTIDKLFIKMSINDKIWVIFLLFLVTLTSVAGSRYFNDIQQFEDQSILTVEAKLAGIIQAKPQNLANLNG
VVSTINAGDATFNNGTVTAYAKLNSGQAIQLTENLSRQFEQAKSDALTSFLLSFLWVVPFALFNYWVATFLGGALWVLYT
TTQKIGEGDLTSRLGFHPGRDEFGTIGCALDKSMDTLTELVNSVKDNANTMSETSAAFEQDMKLSETQIAHQYQTLDSVA
TAMEEMTASAKEVSSISQQATLQSDQDAQQIEHSRTRVQSVISEIETLSSYIEQASTSVSSLNENTTQINDVITTINAIS
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATVEIQAMIEKLQSESRNIASITDRTVQQAQTSSQLIDEI
GGDVTAIADSARSLMDMSIQISTSAEEQSAVANDIASELSDIRSQSNTIREVAQQSTVGVTNLTHASVSLGEVLKRYRTA
>Mature_480_residues
MERLMREVEFRTIDKLFIKMSINDKIWVIFLLFLVTLTSVAGSRYFNDIQQFEDQSILTVEAKLAGIIQAKPQNLANLNG
VVSTINAGDATFNNGTVTAYAKLNSGQAIQLTENLSRQFEQAKSDALTSFLLSFLWVVPFALFNYWVATFLGGALWVLYT
TTQKIGEGDLTSRLGFHPGRDEFGTIGCALDKSMDTLTELVNSVKDNANTMSETSAAFEQDMKLSETQIAHQYQTLDSVA
TAMEEMTASAKEVSSISQQATLQSDQDAQQIEHSRTRVQSVISEIETLSSYIEQASTSVSSLNENTTQINDVITTINAIS
EQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATVEIQAMIEKLQSESRNIASITDRTVQQAQTSSQLIDEI
GGDVTAIADSARSLMDMSIQISTSAEEQSAVANDIASELSDIRSQSNTIREVAQQSTVGVTNLTHASVSLGEVLKRYRTA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=29.2358803986711, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI2367378, Length=302, Percent_Identity=28.1456953642384, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787690, Length=388, Percent_Identity=29.1237113402062, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788194, Length=284, Percent_Identity=29.2253521126761, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789453, Length=242, Percent_Identity=33.0578512396694, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 52385; Mature: 52385

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLMREVEFRTIDKLFIKMSINDKIWVIFLLFLVTLTSVAGSRYFNDIQQFEDQSILTV
CHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
EAKLAGIIQAKPQNLANLNGVVSTINAGDATFNNGTVTAYAKLNSGQAIQLTENLSRQFE
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHH
QAKSDALTSFLLSFLWVVPFALFNYWVATFLGGALWVLYTTTQKIGEGDLTSRLGFHPGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCC
DEFGTIGCALDKSMDTLTELVNSVKDNANTMSETSAAFEQDMKLSETQIAHQYQTLDSVA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAMEEMTASAKEVSSISQQATLQSDQDAQQIEHSRTRVQSVISEIETLSSYIEQASTSVS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNENTTQINDVITTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQ
HHCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHH
ATVEIQAMIEKLQSESRNIASITDRTVQQAQTSSQLIDEIGGDVTAIADSARSLMDMSIQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEE
ISTSAEEQSAVANDIASELSDIRSQSNTIREVAQQSTVGVTNLTHASVSLGEVLKRYRTA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERLMREVEFRTIDKLFIKMSINDKIWVIFLLFLVTLTSVAGSRYFNDIQQFEDQSILTV
CHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
EAKLAGIIQAKPQNLANLNGVVSTINAGDATFNNGTVTAYAKLNSGQAIQLTENLSRQFE
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHH
QAKSDALTSFLLSFLWVVPFALFNYWVATFLGGALWVLYTTTQKIGEGDLTSRLGFHPGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCC
DEFGTIGCALDKSMDTLTELVNSVKDNANTMSETSAAFEQDMKLSETQIAHQYQTLDSVA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAMEEMTASAKEVSSISQQATLQSDQDAQQIEHSRTRVQSVISEIETLSSYIEQASTSVS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNENTTQINDVITTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQ
HHCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHH
ATVEIQAMIEKLQSESRNIASITDRTVQQAQTSSQLIDEIGGDVTAIADSARSLMDMSIQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEE
ISTSAEEQSAVANDIASELSDIRSQSNTIREVAQQSTVGVTNLTHASVSLGEVLKRYRTA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]