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The map label for this gene is lrp [C]

Identifier: 156977073

GI number: 156977073

Start: 1045794

End: 1046246

Strand: Direct

Name: lrp [C]

Synonym: VIBHAR_05858

Alternate gene names: 156977073

Gene position: 1045794-1046246 (Clockwise)

Preceding gene: 156977072

Following gene: 156977087

Centisome position: 47.45

GC content: 43.49

Gene sequence:

>453_bases
ATGATTTCGAACATGACTTTACAAGGCTTAGACAAGTTAGACCGCAAAATACTATCCAGTCTGTTATCTAACGGACGAGA
GTCGATTGCGAATCTATCACGAAATATCGGTTTGTCTCGTACTGCTGTTGCAGAAAGAATTAATAGGTTGGAAAAGACAG
GGATCATCAAGGGCTACACTGCTCAGATCCGTGTTGAAAATGAGGGTCGCAAAGCTGCCAGCTATCTGCTGATCTCTTGT
GAAAAGGGCAAGAAAAATGAAGTAACGAACGCCCTTAAAGAGATTCCAGAGGTACGACTGACCAGCGTTGTGGGAGGTAG
CTTCGACATTATTGCTCTCATCGAAGCACCTGACCTGCAGTCTATTCACCACCTATGTAATGAGATTGAATCTTTTAGCG
GAATTCAGAAACTCGACACAACTGTTGTGCTCCACCAACCAATTAGTCGATAA

Upstream 100 bases:

>100_bases
CTTTGACACAGAAAAACCCCTTCACTCTTGCTGAGCTGTATAACTTTACACTCCCTGAGTCGATTTAATAACAATATAAA
AACCAGAAGAGGCAGAACAC

Downstream 100 bases:

>100_bases
GTTTTTTAGATTCCCGACGAACGTTCTTTTCAGACTAAAAAGCCGCGAGTCAATCGCGGCTTTTTTGTACTTCAATTTTC
GAATTCCTGGCAGCCAATGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MISNMTLQGLDKLDRKILSSLLSNGRESIANLSRNIGLSRTAVAERINRLEKTGIIKGYTAQIRVENEGRKAASYLLISC
EKGKKNEVTNALKEIPEVRLTSVVGGSFDIIALIEAPDLQSIHHLCNEIESFSGIQKLDTTVVLHQPISR

Sequences:

>Translated_150_residues
MISNMTLQGLDKLDRKILSSLLSNGRESIANLSRNIGLSRTAVAERINRLEKTGIIKGYTAQIRVENEGRKAASYLLISC
EKGKKNEVTNALKEIPEVRLTSVVGGSFDIIALIEAPDLQSIHHLCNEIESFSGIQKLDTTVVLHQPISR
>Mature_150_residues
MISNMTLQGLDKLDRKILSSLLSNGRESIANLSRNIGLSRTAVAERINRLEKTGIIKGYTAQIRVENEGRKAASYLLISC
EKGKKNEVTNALKEIPEVRLTSVVGGSFDIIALIEAPDLQSIHHLCNEIESFSGIQKLDTTVVLHQPISR

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=30.0699300699301, Blast_Score=73, Evalue=8e-15,
Organism=Escherichia coli, GI1790182, Length=143, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR013249
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 16525; Mature: 16525

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNMTLQGLDKLDRKILSSLLSNGRESIANLSRNIGLSRTAVAERINRLEKTGIIKGYT
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCE
AQIRVENEGRKAASYLLISCEKGKKNEVTNALKEIPEVRLTSVVGGSFDIIALIEAPDLQ
EEEEECCCCCHHHHEEEEECCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCCHH
SIHHLCNEIESFSGIQKLDTTVVLHQPISR
HHHHHHHHHHHHCCHHHHHHHHEECCCCCC
>Mature Secondary Structure
MISNMTLQGLDKLDRKILSSLLSNGRESIANLSRNIGLSRTAVAERINRLEKTGIIKGYT
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCE
AQIRVENEGRKAASYLLISCEKGKKNEVTNALKEIPEVRLTSVVGGSFDIIALIEAPDLQ
EEEEECCCCCHHHHEEEEECCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCCHH
SIHHLCNEIESFSGIQKLDTTVVLHQPISR
HHHHHHHHHHHHCCHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]