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The map label for this gene is yycF [H]

Identifier: 156976951

GI number: 156976951

Start: 939476

End: 940138

Strand: Direct

Name: yycF [H]

Synonym: VIBHAR_05736

Alternate gene names: 156976951

Gene position: 939476-940138 (Clockwise)

Preceding gene: 156976950

Following gene: 156976952

Centisome position: 42.63

GC content: 45.7

Gene sequence:

>663_bases
GTGAAACAGACACTGCTTCTCGTTGAGGACGATAAAAACTTGGCTGACGGCCTGTTAGTAAGCCTGGAACAAGCAGGATA
TGAGTGTTTACATGTGGAGCGTATTTCAGACGTTGAGCCACAATGGAAAAAGGCTGACTTAGTCATTCTGGACCGCCAAC
TACCAGATGGCGATTCAGTACAATCTCTTCCTGAATGGAAAAAAATTAAAGATGTTCCAGTAATCCTGCTTACTGCACTT
GTTACTGTTAAAGATAAAGTTGCTGGTCTAGATTCTGGCGCGAACGACTACTTAACAAAACCTTTCGCTGAAGCCGAGCT
ATTTGCTCGTATTCGTGCACAACTTCGTGCACCAGATGCAGCAGAACAGGGCAACGCTGACAAAGTGATGACCAAAGACC
TAGAAATCGACCGCGCGACACGCGAAGTTGTATTCAAAGGCGAAATGATCACACTGACTCGTACTGAGTTTGATCTGCTG
TTGTTCTTGGCATCAAACCTTGGCCGCGTGTTTACACGTGATGAACTACTCGACCACGTTTGGGGTTACAACCATTTTCC
TACAACTCGTACAGTAGACACACACGTACTGCAGCTTCGTCAAAAACTGCCAGGTCTTGAAATCGAAACGCTTCGTGGCG
TTGGCTACAAGATGAAAGTGTAA

Upstream 100 bases:

>100_bases
CTAGGGCTTGGATTAACAATAGTTGAATCAATGGTAGGCCGCATGGGCGGAAAAATGTCCCTAATGGGACCACCTACAAC
CTTTATATTGGAGATACCTT

Downstream 100 bases:

>100_bases
TCGCAAGAATGAAAACACTACTTCCTGTAGTTCTATCATTACTGTTATTGAAACCAGTCCATGCAAAGGACTGGTTTCAG
TCCAATACGCCTTTAACTCA

Product: positive response regulator for pho regulon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKQTLLLVEDDKNLADGLLVSLEQAGYECLHVERISDVEPQWKKADLVILDRQLPDGDSVQSLPEWKKIKDVPVILLTAL
VTVKDKVAGLDSGANDYLTKPFAEAELFARIRAQLRAPDAAEQGNADKVMTKDLEIDRATREVVFKGEMITLTRTEFDLL
LFLASNLGRVFTRDELLDHVWGYNHFPTTRTVDTHVLQLRQKLPGLEIETLRGVGYKMKV

Sequences:

>Translated_220_residues
MKQTLLLVEDDKNLADGLLVSLEQAGYECLHVERISDVEPQWKKADLVILDRQLPDGDSVQSLPEWKKIKDVPVILLTAL
VTVKDKVAGLDSGANDYLTKPFAEAELFARIRAQLRAPDAAEQGNADKVMTKDLEIDRATREVVFKGEMITLTRTEFDLL
LFLASNLGRVFTRDELLDHVWGYNHFPTTRTVDTHVLQLRQKLPGLEIETLRGVGYKMKV
>Mature_220_residues
MKQTLLLVEDDKNLADGLLVSLEQAGYECLHVERISDVEPQWKKADLVILDRQLPDGDSVQSLPEWKKIKDVPVILLTAL
VTVKDKVAGLDSGANDYLTKPFAEAELFARIRAQLRAPDAAEQGNADKVMTKDLEIDRATREVVFKGEMITLTRTEFDLL
LFLASNLGRVFTRDELLDHVWGYNHFPTTRTVDTHVLQLRQKLPGLEIETLRGVGYKMKV

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=35.7758620689655, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=37.7880184331797, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=40, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=37.219730941704, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.2869955156951, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=38.6266094420601, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=35.5555555555556, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=33.6283185840708, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=33.6405529953917, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.1266968325792, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=30.2222222222222, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=30.2222222222222, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=28.6343612334802, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=28.6919831223629, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24869; Mature: 24869

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTLLLVEDDKNLADGLLVSLEQAGYECLHVERISDVEPQWKKADLVILDRQLPDGDSV
CCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHCCCCCCCCCCCEEEEECCCCCCCCC
QSLPEWKKIKDVPVILLTALVTVKDKVAGLDSGANDYLTKPFAEAELFARIRAQLRAPDA
CCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCC
AEQGNADKVMTKDLEIDRATREVVFKGEMITLTRTEFDLLLFLASNLGRVFTRDELLDHV
CCCCCCCCEEECCCCHHHHHHHEEECCCEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHH
WGYNHFPTTRTVDTHVLQLRQKLPGLEIETLRGVGYKMKV
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHCCCCEEECC
>Mature Secondary Structure
MKQTLLLVEDDKNLADGLLVSLEQAGYECLHVERISDVEPQWKKADLVILDRQLPDGDSV
CCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHCCCCCCCCCCCEEEEECCCCCCCCC
QSLPEWKKIKDVPVILLTALVTVKDKVAGLDSGANDYLTKPFAEAELFARIRAQLRAPDA
CCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCC
AEQGNADKVMTKDLEIDRATREVVFKGEMITLTRTEFDLLLFLASNLGRVFTRDELLDHV
CCCCCCCCEEECCCCHHHHHHHEEECCCEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHH
WGYNHFPTTRTVDTHVLQLRQKLPGLEIETLRGVGYKMKV
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]