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The map label for this gene is yisQ [H]

Identifier: 156976930

GI number: 156976930

Start: 917690

End: 919075

Strand: Reverse

Name: yisQ [H]

Synonym: VIBHAR_05715

Alternate gene names: 156976930

Gene position: 919075-917690 (Counterclockwise)

Preceding gene: 156976936

Following gene: 156976927

Centisome position: 41.7

GC content: 45.45

Gene sequence:

>1386_bases
ATGCTCTTAACACGTCAATACATAGACAAAGCATTTTGGAAAAAACTGATTGCGATCGGCGTCCCTGTGTCACTGCAATC
CATGCTGTTTTCACTGCTCGGCGCGGTGGACATTTTTATGGTGAGCCAACTTGGTGAATCTGCAACGGCCGCGGTTGGCG
TTGGTAACCGAATCTTTTTCTTTAACCTCGCCGTGGTGTTTGGATTGTGTGGCGCAGTGACGGTTTTAGCTTCTCAGTAT
TATGGCTCTGGAAACCTCTCTGGTATACGCAGAACGTTAGCGCAATCTTGGTTTATTTCGCTAGTGGTGACTTTGCCATT
TATTTGGCTGTACGTGGTTTATGACAAAGAGATCGTCTCTTTTATGGCGGACGATCCTGAGTATGTTGGCTATGCGAGAG
AATACTTAGTAGTGACTGGCTTGAGTCTCATAGGTACCGCTGTCGTTGTTCCCATTGAGTCGGTGTTGAGATCCGTCGGT
GAAGCGAAGATGCCAACTTACGTCAGTACTGCCGCCATCGTTGTGAATGTCTTCCTCAATGCCGTTTTGATCTTTGGCTT
ACTCGGATTTCCACAATGGGGTGTGTTTGGGGCTGCTGTCGGTACTTTTATCTCACGCTTTTTCCAAACTGCGGTGCTGG
TTTACTTCTTTTGTCGCCGATATTCACATCTGCTCCCTACTCGCTCAGACTGGCTTGAAGGCACAGTAAAGAAGTACCGA
AACAAATATTTCAGAGTCTCAATGCCAATGCTTATCCATGATGCGTTGTGGACTGGCGGCTTGATTGTCTACAGCATCAT
TTATGGTCAATTAGGTGTAACTGAACTGGCGATTATCTCGTTCCTATCACCAATTGAAGGTGTGTTGATTTCAACGTTTA
TGGGATTTGCTGTTGCAGCCTCTGTACTTTTGGGTAATGACATTGGCGCTCAAGAATATGACCGTGTAGAGAAAACCGCT
TGGTGGTATGTGTTTACCAGTGCTGTGCTCGCAACAATATTATTCTTAGTCGTTTGGGCGTGTTCACCATTGATTTTGAA
TTTACTGGAGATGAGTCCGCTTACCGATAAACAAATGGCACTGAATGTATGCTTGGTGTTAGCACTGGGTATGATTCTTC
GAGTATTCAACATGGTTGGTATTGGCGGCGTGTTGAAAAGTGGCGCTGATATTCGCTATAGCATCTTCATTGACACATTT
GGTCAATGGGCGATTGGCATTCCGCTTACCTACTACACTGGGATGGTGTTAGGTTTACCGCTGCATTGGGTGTTGATGTC
GCTACTGGTCGAAGAATTAGTAAAAGGCATTCTAACGACTCACCGAATTCAGTCTAAGCGATGGATTAATAACATGGTTG
ATGATGACGCCATCGTGACAGCGTAA

Upstream 100 bases:

>100_bases
TAAAGACTGGATAGTTTGACAAAACTTTGGATGTCTTCGAAAAATACACCGCCAAATCATACGGATAAACTACTCGCATT
GTTCTTAGAGGAGAAATGCG

Downstream 100 bases:

>100_bases
CTATAAAATTGTGCTATGGTTATACAACTAAGAGCTAAAATAACTCTTTGTTTTTAAGGAATAGCTTTAAAGAACTCACA
CCAAAAGGGCACATTCGAAA

Product: Na+-driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MLLTRQYIDKAFWKKLIAIGVPVSLQSMLFSLLGAVDIFMVSQLGESATAAVGVGNRIFFFNLAVVFGLCGAVTVLASQY
YGSGNLSGIRRTLAQSWFISLVVTLPFIWLYVVYDKEIVSFMADDPEYVGYAREYLVVTGLSLIGTAVVVPIESVLRSVG
EAKMPTYVSTAAIVVNVFLNAVLIFGLLGFPQWGVFGAAVGTFISRFFQTAVLVYFFCRRYSHLLPTRSDWLEGTVKKYR
NKYFRVSMPMLIHDALWTGGLIVYSIIYGQLGVTELAIISFLSPIEGVLISTFMGFAVAASVLLGNDIGAQEYDRVEKTA
WWYVFTSAVLATILFLVVWACSPLILNLLEMSPLTDKQMALNVCLVLALGMILRVFNMVGIGGVLKSGADIRYSIFIDTF
GQWAIGIPLTYYTGMVLGLPLHWVLMSLLVEELVKGILTTHRIQSKRWINNMVDDDAIVTA

Sequences:

>Translated_461_residues
MLLTRQYIDKAFWKKLIAIGVPVSLQSMLFSLLGAVDIFMVSQLGESATAAVGVGNRIFFFNLAVVFGLCGAVTVLASQY
YGSGNLSGIRRTLAQSWFISLVVTLPFIWLYVVYDKEIVSFMADDPEYVGYAREYLVVTGLSLIGTAVVVPIESVLRSVG
EAKMPTYVSTAAIVVNVFLNAVLIFGLLGFPQWGVFGAAVGTFISRFFQTAVLVYFFCRRYSHLLPTRSDWLEGTVKKYR
NKYFRVSMPMLIHDALWTGGLIVYSIIYGQLGVTELAIISFLSPIEGVLISTFMGFAVAASVLLGNDIGAQEYDRVEKTA
WWYVFTSAVLATILFLVVWACSPLILNLLEMSPLTDKQMALNVCLVLALGMILRVFNMVGIGGVLKSGADIRYSIFIDTF
GQWAIGIPLTYYTGMVLGLPLHWVLMSLLVEELVKGILTTHRIQSKRWINNMVDDDAIVTA
>Mature_461_residues
MLLTRQYIDKAFWKKLIAIGVPVSLQSMLFSLLGAVDIFMVSQLGESATAAVGVGNRIFFFNLAVVFGLCGAVTVLASQY
YGSGNLSGIRRTLAQSWFISLVVTLPFIWLYVVYDKEIVSFMADDPEYVGYAREYLVVTGLSLIGTAVVVPIESVLRSVG
EAKMPTYVSTAAIVVNVFLNAVLIFGLLGFPQWGVFGAAVGTFISRFFQTAVLVYFFCRRYSHLLPTRSDWLEGTVKKYR
NKYFRVSMPMLIHDALWTGGLIVYSIIYGQLGVTELAIISFLSPIEGVLISTFMGFAVAASVLLGNDIGAQEYDRVEKTA
WWYVFTSAVLATILFLVVWACSPLILNLLEMSPLTDKQMALNVCLVLALGMILRVFNMVGIGGVLKSGADIRYSIFIDTF
GQWAIGIPLTYYTGMVLGLPLHWVLMSLLVEELVKGILTTHRIQSKRWINNMVDDDAIVTA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI22907060, Length=407, Percent_Identity=23.3415233415233, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI226510954, Length=458, Percent_Identity=21.6157205240175, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50962; Mature: 50962

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]