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The map label for this gene is bigR [H]

Identifier: 156976923

GI number: 156976923

Start: 912483

End: 912776

Strand: Direct

Name: bigR [H]

Synonym: VIBHAR_05708

Alternate gene names: 156976923

Gene position: 912483-912776 (Clockwise)

Preceding gene: 156976921

Following gene: 156976924

Centisome position: 41.4

GC content: 45.24

Gene sequence:

>294_bases
ATGGGCGACAGTATGCTACAAAGCGCGACCGAAGCGAGTGAGCTACTTAAAATAATGGCTCATCCAGAGCGCTTAATCGT
GATGTGCAAGCTGATTGAAGGTGAAAAAGGGGTCGGTGAGCTGTTTGAAGGCTCAACATTAAGCCAATCTGCCTTTTCAC
AACACCTCACCGTATTGAGAAAACACAACATCATCAAAGCACGAAAGGTTTCTCAGCAGGTGTTCTATTCGATTTCTGAT
GGAAGAGTCGCTCCGCTGATCGAAGCGTTTAACCAAGTTTTCTGTAAGCAGTAA

Upstream 100 bases:

>100_bases
TAGCTATGTCTAATGTTGTTTATTCTACATTAGTATTGACTTAATGATATTAATTAGTAATATCTAATAAAAGTTAACGT
ATTGATGAAGGGGCATAAGA

Downstream 100 bases:

>100_bases
TTCAAAACTTTATACAGGTGGTTGTTATGTTTGAAGTTCCTTGGGTGTCGCTTTTGGGAGGGGTCATGGTTGGCGCATCA
GCGGTAGTATTGATGCTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MGDSMLQSATEASELLKIMAHPERLIVMCKLIEGEKGVGELFEGSTLSQSAFSQHLTVLRKHNIIKARKVSQQVFYSISD
GRVAPLIEAFNQVFCKQ

Sequences:

>Translated_97_residues
MGDSMLQSATEASELLKIMAHPERLIVMCKLIEGEKGVGELFEGSTLSQSAFSQHLTVLRKHNIIKARKVSQQVFYSISD
GRVAPLIEAFNQVFCKQ
>Mature_96_residues
GDSMLQSATEASELLKIMAHPERLIVMCKLIEGEKGVGELFEGSTLSQSAFSQHLTVLRKHNIIKARKVSQQVFYSISDG
RVAPLIEAFNQVFCKQ

Specific function: Represses an operon that comprises itself, XF_0764, XF_0765, XF_0766 and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=90, Percent_Identity=38.8888888888889, Blast_Score=70, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 10796; Mature: 10665

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDSMLQSATEASELLKIMAHPERLIVMCKLIEGEKGVGELFEGSTLSQSAFSQHLTVLR
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHH
KHNIIKARKVSQQVFYSISDGRVAPLIEAFNQVFCKQ
HHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GDSMLQSATEASELLKIMAHPERLIVMCKLIEGEKGVGELFEGSTLSQSAFSQHLTVLR
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHH
KHNIIKARKVSQQVFYSISDGRVAPLIEAFNQVFCKQ
HHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]