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The map label for this gene is fabH2 [H]

Identifier: 156976915

GI number: 156976915

Start: 901434

End: 902531

Strand: Direct

Name: fabH2 [H]

Synonym: VIBHAR_05699

Alternate gene names: 156976915

Gene position: 901434-902531 (Clockwise)

Preceding gene: 156976913

Following gene: 156976920

Centisome position: 40.9

GC content: 48.27

Gene sequence:

>1098_bases
ATGACAAATTACTACGCTGAAATTACCGGTTGGGGAAAATGCCTTCCACCAGCTACGCTCTCAAACGATGACCTTAGCAC
TTTCCTTGAAACTTCAGATGAATGGATTCGCACCCGTACTGGTATCGAAAACCGTCGCATTAGCCACGTAAACACGTCGG
ATATGGCAACGGTCGCTGCGCAACATGCGATGGCCCGTGCAGGTGTAGAAGCGAGTGACATCGACCTAATCATTGTTGCG
ACTTGCTCTCCTGATTCACTTATCCCAAACATTGCGTCTAAAGTACAACAGAACCTTGGTATCCGTTCTGCTGCCGCATT
CGATTTAAACGCAGCATGTACTGGCTTTGTGTATGGCCTAGAAACTGGCACACGTTTGATTCAATCAGGTAACTACCGTA
ACGCGATCATTATTGGTGCTGAGCGTCTGTCTTTCTACATTGACTGGGCAATGCGCGATACTGCTGTACTGTTCGGCGAT
GGTGCAGGGGCAGTTGTCCTGACTCGTACAGAACAAGAAACCGGTCTACTGCAATCGCAAATTGGTTGTGACGCGAAAGG
TCGTGACATTCTTTCAGTGCCTAAGTTTGGTACATGTATGGATCGCTTTGCTGAAGATAACGGTTACTGGGACTTCAACT
TTGTCGGACAAGAGATCTTCAAACGCGCAGTTAAAGGCATGGGTCTGGCTGCGAAAACGGTTCTGAAAGCTTCTGAACTA
ACCACAGATCAAATCGACGTGGTAATCCCGCACCAAGCAAACATCCGTATTATCCAAACGCTGTGTGACCTTTCTGGTAT
TCCACAAGAAAAAGCGTTTGTGAACATCCAAAACTACGGCAACACATCAGCAGCGACTGTGCCAATTGCACTGTGTGAAG
CGCTAGAACAAGGCCGTGTTAAGTCAGGCGACAACATGCTATTAGCAGCGTTCGGTGCTGGTTTGACATGGGGTGCAGCG
GTACTGAAATGGGGTGACCGCGTAACGCCTATTGCTGAAAGTGACGCAACGCTACCTGAAAGCGATAAGACAGCACTTGA
GCTTTTAGAGCGAGCAATCAAGCTATGTAACGAACGCCCTCGTGGTGAAGACGCATAA

Upstream 100 bases:

>100_bases
TTATTTTTTAGCCTGCCGAAATATAAGACGGCAAGTCTGTATTTGGACCCGAACAGGTTCTAAGAAATCTCATTAAAATA
CAACAATAAATAGGTCTGCG

Downstream 100 bases:

>100_bases
GCGCTTGTATTAGCATCATAGGAAAAGGGAGCATAACGCTCTAATGCCGTTCACTTAAGGTGATCGGCATTGTTTTTTCT
AGGGTATCGGCTTGGCTTTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2 [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTNYYAEITGWGKCLPPATLSNDDLSTFLETSDEWIRTRTGIENRRISHVNTSDMATVAAQHAMARAGVEASDIDLIIVA
TCSPDSLIPNIASKVQQNLGIRSAAAFDLNAACTGFVYGLETGTRLIQSGNYRNAIIIGAERLSFYIDWAMRDTAVLFGD
GAGAVVLTRTEQETGLLQSQIGCDAKGRDILSVPKFGTCMDRFAEDNGYWDFNFVGQEIFKRAVKGMGLAAKTVLKASEL
TTDQIDVVIPHQANIRIIQTLCDLSGIPQEKAFVNIQNYGNTSAATVPIALCEALEQGRVKSGDNMLLAAFGAGLTWGAA
VLKWGDRVTPIAESDATLPESDKTALELLERAIKLCNERPRGEDA

Sequences:

>Translated_365_residues
MTNYYAEITGWGKCLPPATLSNDDLSTFLETSDEWIRTRTGIENRRISHVNTSDMATVAAQHAMARAGVEASDIDLIIVA
TCSPDSLIPNIASKVQQNLGIRSAAAFDLNAACTGFVYGLETGTRLIQSGNYRNAIIIGAERLSFYIDWAMRDTAVLFGD
GAGAVVLTRTEQETGLLQSQIGCDAKGRDILSVPKFGTCMDRFAEDNGYWDFNFVGQEIFKRAVKGMGLAAKTVLKASEL
TTDQIDVVIPHQANIRIIQTLCDLSGIPQEKAFVNIQNYGNTSAATVPIALCEALEQGRVKSGDNMLLAAFGAGLTWGAA
VLKWGDRVTPIAESDATLPESDKTALELLERAIKLCNERPRGEDA
>Mature_364_residues
TNYYAEITGWGKCLPPATLSNDDLSTFLETSDEWIRTRTGIENRRISHVNTSDMATVAAQHAMARAGVEASDIDLIIVAT
CSPDSLIPNIASKVQQNLGIRSAAAFDLNAACTGFVYGLETGTRLIQSGNYRNAIIIGAERLSFYIDWAMRDTAVLFGDG
AGAVVLTRTEQETGLLQSQIGCDAKGRDILSVPKFGTCMDRFAEDNGYWDFNFVGQEIFKRAVKGMGLAAKTVLKASELT
TDQIDVVIPHQANIRIIQTLCDLSGIPQEKAFVNIQNYGNTSAATVPIALCEALEQGRVKSGDNMLLAAFGAGLTWGAAV
LKWGDRVTPIAESDATLPESDKTALELLERAIKLCNERPRGEDA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=39.4409937888199, Blast_Score=228, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 39448; Mature: 39317

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNYYAEITGWGKCLPPATLSNDDLSTFLETSDEWIRTRTGIENRRISHVNTSDMATVAA
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCEECCCCCHHHHHHHH
QHAMARAGVEASDIDLIIVATCSPDSLIPNIASKVQQNLGIRSAAAFDLNAACTGFVYGL
HHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHEEEEH
ETGTRLIQSGNYRNAIIIGAERLSFYIDWAMRDTAVLFGDGAGAVVLTRTEQETGLLQSQ
HHHHHHHHCCCCCCEEEEEEEHEEEEEEEEECCEEEEEECCCCEEEEEECCHHHHHHHHH
IGCDAKGRDILSVPKFGTCMDRFAEDNGYWDFNFVGQEIFKRAVKGMGLAAKTVLKASEL
CCCCCCCCCEECCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
TTDQIDVVIPHQANIRIIQTLCDLSGIPQEKAFVNIQNYGNTSAATVPIALCEALEQGRV
CCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
KSGDNMLLAAFGAGLTWGAAVLKWGDRVTPIAESDATLPESDKTALELLERAIKLCNERP
CCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
RGEDA
CCCCC
>Mature Secondary Structure 
TNYYAEITGWGKCLPPATLSNDDLSTFLETSDEWIRTRTGIENRRISHVNTSDMATVAA
CCEEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCEECCCCCHHHHHHHH
QHAMARAGVEASDIDLIIVATCSPDSLIPNIASKVQQNLGIRSAAAFDLNAACTGFVYGL
HHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHEEEEH
ETGTRLIQSGNYRNAIIIGAERLSFYIDWAMRDTAVLFGDGAGAVVLTRTEQETGLLQSQ
HHHHHHHHCCCCCCEEEEEEEHEEEEEEEEECCEEEEEECCCCEEEEEECCHHHHHHHHH
IGCDAKGRDILSVPKFGTCMDRFAEDNGYWDFNFVGQEIFKRAVKGMGLAAKTVLKASEL
CCCCCCCCCEECCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
TTDQIDVVIPHQANIRIIQTLCDLSGIPQEKAFVNIQNYGNTSAATVPIALCEALEQGRV
CCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
KSGDNMLLAAFGAGLTWGAAVLKWGDRVTPIAESDATLPESDKTALELLERAIKLCNERP
CCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
RGEDA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]