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The map label for this gene is sbcD [H]

Identifier: 156976877

GI number: 156976877

Start: 860672

End: 861811

Strand: Direct

Name: sbcD [H]

Synonym: VIBHAR_05653

Alternate gene names: 156976877

Gene position: 860672-861811 (Clockwise)

Preceding gene: 156976876

Following gene: 156976878

Centisome position: 39.05

GC content: 45.79

Gene sequence:

>1140_bases
ATGAAGTTTATCCATACCTCAGATTGGCACCTTGGCCGACAGTTTCATAACGTCTCTTTGCTTGGCGATCAGCAAGCGGT
TCTCGACCAGTTAATCCAATACGTTGAAGACAACCCTGTTGATGCGGTGGTGGTGGCTGGTGATATTTATGACCGTTCTG
TCCCACCAACCATTGCGATTGAACTACTTAACAAAGTAGTGAAGCGAATCTGTGGTGAGCTAAATACGCCGATGATTCTG
ATTTCTGGCAACCATGATGGTGCTGAACGTTTGGGTTTTGGTTCAGAACAGATGAAAAATGCGGGCCTTCACATTATCAG
TAACTTCGAAGACATGCTTACCCCTGTTGTTATTGAAACCGAAAGCGCAGGGCAAGTTGCTTTTTATGGCATGCCTTATA
ACGACCCTGAGCAAGTCCGTTTTGCCTACCAAGAACCCGTTTCGACCCACGATCAAGCGCACAAGTTACTTGCAGAGAAA
ATCACGGAGCAGTTCCAACCAGAACAACGCAACGTGTTAGTCAGCCACTGCTTTGTCGATGGTGCCATTGAGTCTGAATC
TGAGCGTCCACTTTCGATTGGCGGTTCCGACCGTGTCAGTCACGAGCATTTTCTCAACTTTGACTATGTAGCGTTGGGGC
ATTTGCACCAGCCACAGAAAAAAGGCGAAGAGTACATTCGTTATTCTGGTTCACTGATGAAATACAGTTTTGGTGAACAA
AACCAGAAGAAAGGTTTCACGCTGGTGGAAATTGACCAAAATGGTTTTGTATCGGCAGAGCATATTGACCTTGCCGCACC
TCATGAGATGCGAATCGTTGAAGGCGAACTTGAACAAGTAATAGAGCAGGGCAAAACCGATCCGAAAAACGAAGACTACC
TGTTGGTACGTTTGATGGATAAGCACGCGATCTTAAACCCAATGGAAAAGCTACGTACTGTTTACCCAAATGTTTTGCAC
CTAGAAAAGCCGGGCATGTTAATTGGTGTCGAGCAGGAAATGGCGCAAGCGAAGTTGGCGAGAAGTGAGATAGACATGTT
CCGAGATTTCTTTTCGGAAGCGCAAGACGGCCAATTATCGCAAGAACAAGATCAAGCGATCAGTGACATTATCAAACAAC
TTTCTCAGCAAGCTCAGTAA

Upstream 100 bases:

>100_bases
GCCTAAACCTTGTCATAAACCACATGAAAAGCTTACGAACTCACGATATCCTAGGGGGATAATAAGATAGCGCCATATTG
ATGGCAGAAAGTGAATTCGA

Downstream 100 bases:

>100_bases
GGACCAAACATGAAACCCATTAAACTGACAATGCAGGCTTTTGGTCCGTTTGCTCAAACAGAAACGATTGAATTCGACAA
GCTGGGTACTAACCCTCTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKFIHTSDWHLGRQFHNVSLLGDQQAVLDQLIQYVEDNPVDAVVVAGDIYDRSVPPTIAIELLNKVVKRICGELNTPMIL
ISGNHDGAERLGFGSEQMKNAGLHIISNFEDMLTPVVIETESAGQVAFYGMPYNDPEQVRFAYQEPVSTHDQAHKLLAEK
ITEQFQPEQRNVLVSHCFVDGAIESESERPLSIGGSDRVSHEHFLNFDYVALGHLHQPQKKGEEYIRYSGSLMKYSFGEQ
NQKKGFTLVEIDQNGFVSAEHIDLAAPHEMRIVEGELEQVIEQGKTDPKNEDYLLVRLMDKHAILNPMEKLRTVYPNVLH
LEKPGMLIGVEQEMAQAKLARSEIDMFRDFFSEAQDGQLSQEQDQAISDIIKQLSQQAQ

Sequences:

>Translated_379_residues
MKFIHTSDWHLGRQFHNVSLLGDQQAVLDQLIQYVEDNPVDAVVVAGDIYDRSVPPTIAIELLNKVVKRICGELNTPMIL
ISGNHDGAERLGFGSEQMKNAGLHIISNFEDMLTPVVIETESAGQVAFYGMPYNDPEQVRFAYQEPVSTHDQAHKLLAEK
ITEQFQPEQRNVLVSHCFVDGAIESESERPLSIGGSDRVSHEHFLNFDYVALGHLHQPQKKGEEYIRYSGSLMKYSFGEQ
NQKKGFTLVEIDQNGFVSAEHIDLAAPHEMRIVEGELEQVIEQGKTDPKNEDYLLVRLMDKHAILNPMEKLRTVYPNVLH
LEKPGMLIGVEQEMAQAKLARSEIDMFRDFFSEAQDGQLSQEQDQAISDIIKQLSQQAQ
>Mature_379_residues
MKFIHTSDWHLGRQFHNVSLLGDQQAVLDQLIQYVEDNPVDAVVVAGDIYDRSVPPTIAIELLNKVVKRICGELNTPMIL
ISGNHDGAERLGFGSEQMKNAGLHIISNFEDMLTPVVIETESAGQVAFYGMPYNDPEQVRFAYQEPVSTHDQAHKLLAEK
ITEQFQPEQRNVLVSHCFVDGAIESESERPLSIGGSDRVSHEHFLNFDYVALGHLHQPQKKGEEYIRYSGSLMKYSFGEQ
NQKKGFTLVEIDQNGFVSAEHIDLAAPHEMRIVEGELEQVIEQGKTDPKNEDYLLVRLMDKHAILNPMEKLRTVYPNVLH
LEKPGMLIGVEQEMAQAKLARSEIDMFRDFFSEAQDGQLSQEQDQAISDIIKQLSQQAQ

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

Organism=Escherichia coli, GI1786598, Length=296, Percent_Identity=27.7027027027027, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 42869; Mature: 42869

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIHTSDWHLGRQFHNVSLLGDQQAVLDQLIQYVEDNPVDAVVVAGDIYDRSVPPTIAI
CCCEECCCCHHCHHHCCEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHCCCCCHHHHH
ELLNKVVKRICGELNTPMILISGNHDGAERLGFGSEQMKNAGLHIISNFEDMLTPVVIET
HHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCHHHHHCCCEEEECCHHHHCCCEEEEE
ESAGQVAFYGMPYNDPEQVRFAYQEPVSTHDQAHKLLAEKITEQFQPEQRNVLVSHCFVD
CCCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHCEEHHHHEEC
GAIESESERPLSIGGSDRVSHEHFLNFDYVALGHLHQPQKKGEEYIRYSGSLMKYSFGEQ
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCEEEECCCCC
NQKKGFTLVEIDQNGFVSAEHIDLAAPHEMRIVEGELEQVIEQGKTDPKNEDYLLVRLMD
CCCCCCEEEEECCCCCEEECCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEEEEC
KHAILNPMEKLRTVYPNVLHLEKPGMLIGVEQEMAQAKLARSEIDMFRDFFSEAQDGQLS
HHHHCCHHHHHHHHCCCEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QEQDQAISDIIKQLSQQAQ
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFIHTSDWHLGRQFHNVSLLGDQQAVLDQLIQYVEDNPVDAVVVAGDIYDRSVPPTIAI
CCCEECCCCHHCHHHCCEEEECCHHHHHHHHHHHHCCCCCCEEEEECCHHCCCCCHHHHH
ELLNKVVKRICGELNTPMILISGNHDGAERLGFGSEQMKNAGLHIISNFEDMLTPVVIET
HHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCHHHHHCCCEEEECCHHHHCCCEEEEE
ESAGQVAFYGMPYNDPEQVRFAYQEPVSTHDQAHKLLAEKITEQFQPEQRNVLVSHCFVD
CCCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHCEEHHHHEEC
GAIESESERPLSIGGSDRVSHEHFLNFDYVALGHLHQPQKKGEEYIRYSGSLMKYSFGEQ
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCEEEECCCCC
NQKKGFTLVEIDQNGFVSAEHIDLAAPHEMRIVEGELEQVIEQGKTDPKNEDYLLVRLMD
CCCCCCEEEEECCCCCEEECCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEEEEC
KHAILNPMEKLRTVYPNVLHLEKPGMLIGVEQEMAQAKLARSEIDMFRDFFSEAQDGQLS
HHHHCCHHHHHHHHCCCEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QEQDQAISDIIKQLSQQAQ
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA