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The map label for this gene is 156976571

Identifier: 156976571

GI number: 156976571

Start: 575981

End: 577318

Strand: Reverse

Name: 156976571

Synonym: VIBHAR_05345

Alternate gene names: NA

Gene position: 577318-575981 (Counterclockwise)

Preceding gene: 156976572

Following gene: 156976568

Centisome position: 26.19

GC content: 48.36

Gene sequence:

>1338_bases
ATGTCTTCTACTTCTTCTAATGCCCAACCGACGTTAGCGAAACAACTCTTTACGATGACTTGGCCAATGCTGTTTGGCGT
TCTGTCATTAATGAGCTTCCAATTAGTTGATAGTGCGTTCATTGGCCAACTTGGTGTCCTTCCCCTTGCAGCACAAGGTT
TCACTCTTCCCCTTCAAATGGTGGTGATTGGTATTCAAGTTGGCTTAGGCATCGCGACCACAGCGGTCATCTCAAAAGCA
CTCGGCGCAAACAACGCTCGCTATGCTAAGCAGCTAGGAGGCCTAGTGCTTATGATTGGCTCTATTGGTGTTGCGGTCTT
CGACCTGCTTATTTGGCTGCTGCGCTACCCTATCCTCTCTCTATTGAGCGCACCAGATTCAGTTATGCCCATCATCGATA
GCTATTGGCCATGGTGGCTATTGAGTTCATGGGTAGGAGCGGTACTGTATTTCTATTACAGTATCTGCCGAGCCAATGGC
AACACCATGCTGCCTGGCACCATGATGATGGTCACCAGTGGTGTGAACTTAGTGCTCGATCCACTGTTTATCTTTACTTT
CGATCTCGGTATCAACGGTGCCGCTATTGCAACAGTGATTGCTTTTGGCTTCGGTATTTTAGTAGTGGCTCCTCGCGTTC
AGAGGAATCATTGGGCTAGCTTCGAATGGCACGATTTGAATGTAGTTAAGAGCGTTACATCCATCGGCAATATCATGGGG
CCGGCAATGATCAGCCAACTGTTGCCACCACTTTCTTCGATGTTGGCAACTAAGCTACTTGCGGGATTTGGTACCGCAGC
CGTCGCTTCTTGGGCTTTGGGATCTCGCTACGAATTCTTTGCCATCGTTTCGGTATTGGCATTAACCATGTCTATGCCGC
CAATGGTGGGTCGATTACTGGGTGCGAAAAACTACGCTGACATTCAATCGCTGATTTCTATCGCGGTGAAATTTGTTCTT
GGCTTCCAGCTTCTAATCGCCATCATCACCTTTGTCGCTGCTGATCCACTTGCTCTGCTTATGACCAGTGATGCTGAAGT
GACCAGCGTGCTTGAAATGCATTTGATGATTGTGCCTATCAGCTTAGGCTCGCTGGGCGTGTGTATGTTGATGGTGTCGA
TCTGCAATGCTTTAGGTAAGTCGTACACAGCGCTAACCATCTCCGCACTACGACTGTTTTTGTTCTTCCTTCCGTGCCTT
TGGGTTGGCGCGCAAATGGGAGGCATTAAAGGGCTGCTTATTGGCGCTTGCCTAGGTAACCTCATGGCAGGTATCGCTGC
TTATTTAACATACCGTAAAACCATTCATAAGCTCGTTTCTGCTGAAGCTGCGGCTTAA

Upstream 100 bases:

>100_bases
CCCCGAGCAAGCACGCCTTGCTCGGGGTTTCTTTTTGTCTCTTTGTTGTACAGTGTGTACAATAAACACAATTTCCGTTC
CAAAAACACCCATATTTTAT

Downstream 100 bases:

>100_bases
GAGAGCCAAATAAAACAAAGCCCTCACGATGAGGGCTTTGTTCTTTAGACCATTTAGCATGATGCTGTTTTAAAGCTTTA
GAAAAGCAAGCGCCTAGTTT

Product: Na+-driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSSTSSNAQPTLAKQLFTMTWPMLFGVLSLMSFQLVDSAFIGQLGVLPLAAQGFTLPLQMVVIGIQVGLGIATTAVISKA
LGANNARYAKQLGGLVLMIGSIGVAVFDLLIWLLRYPILSLLSAPDSVMPIIDSYWPWWLLSSWVGAVLYFYYSICRANG
NTMLPGTMMMVTSGVNLVLDPLFIFTFDLGINGAAIATVIAFGFGILVVAPRVQRNHWASFEWHDLNVVKSVTSIGNIMG
PAMISQLLPPLSSMLATKLLAGFGTAAVASWALGSRYEFFAIVSVLALTMSMPPMVGRLLGAKNYADIQSLISIAVKFVL
GFQLLIAIITFVAADPLALLMTSDAEVTSVLEMHLMIVPISLGSLGVCMLMVSICNALGKSYTALTISALRLFLFFLPCL
WVGAQMGGIKGLLIGACLGNLMAGIAAYLTYRKTIHKLVSAEAAA

Sequences:

>Translated_445_residues
MSSTSSNAQPTLAKQLFTMTWPMLFGVLSLMSFQLVDSAFIGQLGVLPLAAQGFTLPLQMVVIGIQVGLGIATTAVISKA
LGANNARYAKQLGGLVLMIGSIGVAVFDLLIWLLRYPILSLLSAPDSVMPIIDSYWPWWLLSSWVGAVLYFYYSICRANG
NTMLPGTMMMVTSGVNLVLDPLFIFTFDLGINGAAIATVIAFGFGILVVAPRVQRNHWASFEWHDLNVVKSVTSIGNIMG
PAMISQLLPPLSSMLATKLLAGFGTAAVASWALGSRYEFFAIVSVLALTMSMPPMVGRLLGAKNYADIQSLISIAVKFVL
GFQLLIAIITFVAADPLALLMTSDAEVTSVLEMHLMIVPISLGSLGVCMLMVSICNALGKSYTALTISALRLFLFFLPCL
WVGAQMGGIKGLLIGACLGNLMAGIAAYLTYRKTIHKLVSAEAAA
>Mature_444_residues
SSTSSNAQPTLAKQLFTMTWPMLFGVLSLMSFQLVDSAFIGQLGVLPLAAQGFTLPLQMVVIGIQVGLGIATTAVISKAL
GANNARYAKQLGGLVLMIGSIGVAVFDLLIWLLRYPILSLLSAPDSVMPIIDSYWPWWLLSSWVGAVLYFYYSICRANGN
TMLPGTMMMVTSGVNLVLDPLFIFTFDLGINGAAIATVIAFGFGILVVAPRVQRNHWASFEWHDLNVVKSVTSIGNIMGP
AMISQLLPPLSSMLATKLLAGFGTAAVASWALGSRYEFFAIVSVLALTMSMPPMVGRLLGAKNYADIQSLISIAVKFVLG
FQLLIAIITFVAADPLALLMTSDAEVTSVLEMHLMIVPISLGSLGVCMLMVSICNALGKSYTALTISALRLFLFFLPCLW
VGAQMGGIKGLLIGACLGNLMAGIAAYLTYRKTIHKLVSAEAAA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47439; Mature: 47307

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSTSSNAQPTLAKQLFTMTWPMLFGVLSLMSFQLVDSAFIGQLGVLPLAAQGFTLPLQM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHH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HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]