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The map label for this gene is ndh [H]

Identifier: 156976398

GI number: 156976398

Start: 428498

End: 429751

Strand: Direct

Name: ndh [H]

Synonym: VIBHAR_05171

Alternate gene names: 156976398

Gene position: 428498-429751 (Clockwise)

Preceding gene: 156976397

Following gene: 156976399

Centisome position: 19.44

GC content: 47.45

Gene sequence:

>1254_bases
ATGAATGGTTTCCGGGAGGGGAGTATGTCGAATTTTGTTGTTGTCGGTGGTGGTGCTGCAGGCCTAGAAATGGTGACGCG
TTTAGCGAGCAGTTTTGCGGGTAAATCTGGCCACACCGTCACTTTGGTTGAACCATCTTCTCATCACTTATGGAAACCAA
GACTGCATGAAATTGCGGCGGGCACGTTTGACAATGAGCTCGATTCGGTGGCGTTTCGCCTTCATGCTGCTTGCCACGGT
TACCAGTATGTTCAAGCGCGTATGTCAGGATTAGATCGAGCAAACAAAACGATTACCGTAAGCGCTGAGCTCTCACCAGA
ACAAACATTGAAATACGATTACCTTGTGATTGCAGTGGGTGCGATCAGTAATGATTTCAAAATTCCGGGTGTGAGCGATC
ATTGTTTGTTCTTAGATTCTGCCTCTCAAGCAGAAAAAGCATGGGAGCAGATGAAACAGATGCTGGCGAACGGTGGTGCT
CACCGTGTATCTATTGTGGGGGCTGGTGCGACTGGTGTTGAGTTGGGTGCTGAGTGGGCTAAAGTGAGCAAGCAATTAAA
CCGCTATCAAAATGATACTCAGCTTTCTATTACGCTTATTGAAGCCGCAGACCGCGTATTGCCCGCAAGCGCTGATTGCA
TGTCTGAAAAAGTACTCAAGAAACTTCAAAAGCAGGGCGTTAACGTCCGCTTAAACGCAAGGGTTAAGCGTGCAGAAGCG
GATCGCATTGTAACAGAAAATGAGGTCATTCCTGCTGATCTACAAATTTGGGCGGCAGGTATTCGATGCCCAGACTGGTT
AGCGAATCTCGATGGTCTGGAAAGCAACCGTATTAACCAACTTAAAGTGTTACCAACGTTGCAAACCACTCTTGATGAGA
GCGTTTTTGTCATCGGTGACAGTGCTGAATGTCCACAAGAGGATGGACGTGTCGTACCACCACGAGCACAAGCAGCCAAC
CAAGCAGCGGCGCATTTGGCGAAGCAGTTTAAGCGCTTGGTGAAAGGCAAAGAGCTTAAGCCGTTTGTATTCAAAGATGG
TGGCATGGTAGTAGCACTTGGGCATGACTACGCGGTTGGCGCGTTGATGAATGACAAAGTCGTGTTACGTGGACGCTATG
TTCGTCGTTTATACGACACCATTTTTAGACTACATCAACGTGTCATTTTTGGCTGGTTCCGAGTATCAGCGTTGGTTGTG
CTTAAACGCGTAAAAGGTTTATTGAACCCTTATTACAAAGGCTCTTGGTCTTAA

Upstream 100 bases:

>100_bases
ATAGTTATTTTCTTTTTCTGCTTATTATCATTTATTTTCAACTCAATATAATGCTCGCCATTCCAAACGTATTTACTGCG
TTTATGATTTTTATCTTTCG

Downstream 100 bases:

>100_bases
TCCCAGTCAGTATTATTCGTTTCTGTCTTTTCACTATTATCGAGCGCCCAAATCATAACGATTTGTGGCGCTAGGTGTTT
TTTATGCGTCATTTGCAACT

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNGFREGSMSNFVVVGGGAAGLEMVTRLASSFAGKSGHTVTLVEPSSHHLWKPRLHEIAAGTFDNELDSVAFRLHAACHG
YQYVQARMSGLDRANKTITVSAELSPEQTLKYDYLVIAVGAISNDFKIPGVSDHCLFLDSASQAEKAWEQMKQMLANGGA
HRVSIVGAGATGVELGAEWAKVSKQLNRYQNDTQLSITLIEAADRVLPASADCMSEKVLKKLQKQGVNVRLNARVKRAEA
DRIVTENEVIPADLQIWAAGIRCPDWLANLDGLESNRINQLKVLPTLQTTLDESVFVIGDSAECPQEDGRVVPPRAQAAN
QAAAHLAKQFKRLVKGKELKPFVFKDGGMVVALGHDYAVGALMNDKVVLRGRYVRRLYDTIFRLHQRVIFGWFRVSALVV
LKRVKGLLNPYYKGSWS

Sequences:

>Translated_417_residues
MNGFREGSMSNFVVVGGGAAGLEMVTRLASSFAGKSGHTVTLVEPSSHHLWKPRLHEIAAGTFDNELDSVAFRLHAACHG
YQYVQARMSGLDRANKTITVSAELSPEQTLKYDYLVIAVGAISNDFKIPGVSDHCLFLDSASQAEKAWEQMKQMLANGGA
HRVSIVGAGATGVELGAEWAKVSKQLNRYQNDTQLSITLIEAADRVLPASADCMSEKVLKKLQKQGVNVRLNARVKRAEA
DRIVTENEVIPADLQIWAAGIRCPDWLANLDGLESNRINQLKVLPTLQTTLDESVFVIGDSAECPQEDGRVVPPRAQAAN
QAAAHLAKQFKRLVKGKELKPFVFKDGGMVVALGHDYAVGALMNDKVVLRGRYVRRLYDTIFRLHQRVIFGWFRVSALVV
LKRVKGLLNPYYKGSWS
>Mature_417_residues
MNGFREGSMSNFVVVGGGAAGLEMVTRLASSFAGKSGHTVTLVEPSSHHLWKPRLHEIAAGTFDNELDSVAFRLHAACHG
YQYVQARMSGLDRANKTITVSAELSPEQTLKYDYLVIAVGAISNDFKIPGVSDHCLFLDSASQAEKAWEQMKQMLANGGA
HRVSIVGAGATGVELGAEWAKVSKQLNRYQNDTQLSITLIEAADRVLPASADCMSEKVLKKLQKQGVNVRLNARVKRAEA
DRIVTENEVIPADLQIWAAGIRCPDWLANLDGLESNRINQLKVLPTLQTTLDESVFVIGDSAECPQEDGRVVPPRAQAAN
QAAAHLAKQFKRLVKGKELKPFVFKDGGMVVALGHDYAVGALMNDKVVLRGRYVRRLYDTIFRLHQRVIFGWFRVSALVV
LKRVKGLLNPYYKGSWS

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=429, Percent_Identity=40.3263403263403, Blast_Score=303, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6323794, Length=377, Percent_Identity=26.790450928382, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323515, Length=479, Percent_Identity=25.0521920668058, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320118, Length=369, Percent_Identity=24.390243902439, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 45810; Mature: 45810

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFREGSMSNFVVVGGGAAGLEMVTRLASSFAGKSGHTVTLVEPSSHHLWKPRLHEIAA
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHC
GTFDNELDSVAFRLHAACHGYQYVQARMSGLDRANKTITVSAELSPEQTLKYDYLVIAVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHCEEEEEEEEEE
AISNDFKIPGVSDHCLFLDSASQAEKAWEQMKQMLANGGAHRVSIVGAGATGVELGAEWA
ECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
KVSKQLNRYQNDTQLSITLIEAADRVLPASADCMSEKVLKKLQKQGVNVRLNARVKRAEA
HHHHHHHHCCCCCEEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECEEEHHHH
DRIVTENEVIPADLQIWAAGIRCPDWLANLDGLESNRINQLKVLPTLQTTLDESVFVIGD
CCEECCCCCCCCCHHEEEECCCCHHHHHCCCCCCCCCCCEEEEECHHHHHCCCCEEEEEC
SAECPQEDGRVVPPRAQAANQAAAHLAKQFKRLVKGKELKPFVFKDGGMVVALGHDYAVG
CCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCEEEE
ALMNDKVVLRGRYVRRLYDTIFRLHQRVIFGWFRVSALVVLKRVKGLLNPYYKGSWS
EEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNGFREGSMSNFVVVGGGAAGLEMVTRLASSFAGKSGHTVTLVEPSSHHLWKPRLHEIAA
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHC
GTFDNELDSVAFRLHAACHGYQYVQARMSGLDRANKTITVSAELSPEQTLKYDYLVIAVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHCEEEEEEEEEE
AISNDFKIPGVSDHCLFLDSASQAEKAWEQMKQMLANGGAHRVSIVGAGATGVELGAEWA
ECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
KVSKQLNRYQNDTQLSITLIEAADRVLPASADCMSEKVLKKLQKQGVNVRLNARVKRAEA
HHHHHHHHCCCCCEEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECEEEHHHH
DRIVTENEVIPADLQIWAAGIRCPDWLANLDGLESNRINQLKVLPTLQTTLDESVFVIGD
CCEECCCCCCCCCHHEEEECCCCHHHHHCCCCCCCCCCCEEEEECHHHHHCCCCEEEEEC
SAECPQEDGRVVPPRAQAANQAAAHLAKQFKRLVKGKELKPFVFKDGGMVVALGHDYAVG
CCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCEEEE
ALMNDKVVLRGRYVRRLYDTIFRLHQRVIFGWFRVSALVVLKRVKGLLNPYYKGSWS
EEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]