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The map label for this gene is zraR [H]

Identifier: 156976385

GI number: 156976385

Start: 397918

End: 398547

Strand: Reverse

Name: zraR [H]

Synonym: VIBHAR_05158

Alternate gene names: 156976385

Gene position: 398547-397918 (Counterclockwise)

Preceding gene: 156976386

Following gene: 156976381

Centisome position: 18.08

GC content: 45.24

Gene sequence:

>630_bases
ATGACATTAAAACTCTTACTTGCAGAAGACGACACAGAATTGCGAGAGGTTCTCGTTGAAGCATTAACCTTGGAATCGTT
TCAAGTGGTCGCATGTGATAATGCAGAAGATGCATTAGACATCGCCAGTGAACAACATTTCGACCTGGCGCTATTTGACG
TCGTAATGACGGGGATGACTGGTATCGAGGCCCTTTCTACCTTAAGAAGGCAGCATCCCAACATTGGCATTATCATCACC
ACTGCATTTGCTACAGTCGACGTAGCGGTAGACGCCATGAAAAAAGGAGCGGATGAGTTTCTCACTAAGCCATTCAATCT
CTCAGCTCTATCTGTCACCTTAAGGCGAGTCCATGCTGAACGGTCACCAAAGTCTCCTCTCGATGAGAGAAAGCATGACC
AAATCTTTAGTGCTCTCTCCAACCCGATTCGCCGCTCGGTTATCAAGCAACTAAAAATCCATCGTAAAATGAAGTTCATG
GATCTGTGTCGAGTCGTCGGTATCGAAGACCATACCAAATTCAACTTCCACCTAAAACAACTGGTCAACAGCGGATTGGT
TATTAAAGAAGATGGGCGAATTTACTCGCTTACCGAACAAGGTCAACAAGTCCACTCCAGCATGCTTTAA

Upstream 100 bases:

>100_bases
TTATATTACAACACGGTGGCGAGCTAAACTTGAGGAACTCGAAGAAGAGTGACCACATTACTGGCTTAACGGTTGAGATC
CGCTTACCAAGGAACATTGA

Downstream 100 bases:

>100_bases
CGTATCTTTAAAATGCATAAAAAAGCCGACTGAGTGTCGGCTTCTTAATTTTAATTCGTTGTCCCGTCCTGAGATAAACT
TTACATGGATTATCTGCAGC

Product: transcriptional regulatory protein CpxR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTLKLLLAEDDTELREVLVEALTLESFQVVACDNAEDALDIASEQHFDLALFDVVMTGMTGIEALSTLRRQHPNIGIIIT
TAFATVDVAVDAMKKGADEFLTKPFNLSALSVTLRRVHAERSPKSPLDERKHDQIFSALSNPIRRSVIKQLKIHRKMKFM
DLCRVVGIEDHTKFNFHLKQLVNSGLVIKEDGRIYSLTEQGQQVHSSML

Sequences:

>Translated_209_residues
MTLKLLLAEDDTELREVLVEALTLESFQVVACDNAEDALDIASEQHFDLALFDVVMTGMTGIEALSTLRRQHPNIGIIIT
TAFATVDVAVDAMKKGADEFLTKPFNLSALSVTLRRVHAERSPKSPLDERKHDQIFSALSNPIRRSVIKQLKIHRKMKFM
DLCRVVGIEDHTKFNFHLKQLVNSGLVIKEDGRIYSLTEQGQQVHSSML
>Mature_208_residues
TLKLLLAEDDTELREVLVEALTLESFQVVACDNAEDALDIASEQHFDLALFDVVMTGMTGIEALSTLRRQHPNIGIIITT
AFATVDVAVDAMKKGADEFLTKPFNLSALSVTLRRVHAERSPKSPLDERKHDQIFSALSNPIRRSVIKQLKIHRKMKFMD
LCRVVGIEDHTKFNFHLKQLVNSGLVIKEDGRIYSLTEQGQQVHSSML

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=32.7433628318584, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=33.8983050847458, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=103, Percent_Identity=32.0388349514563, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082012, Length=120, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=113, Percent_Identity=30.0884955752212, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=130, Percent_Identity=32.3076923076923, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786599, Length=125, Percent_Identity=28.8, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788905, Length=149, Percent_Identity=28.1879194630872, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 23499; Mature: 23367

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKLLLAEDDTELREVLVEALTLESFQVVACDNAEDALDIASEQHFDLALFDVVMTGMT
CEEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHCCH
GIEALSTLRRQHPNIGIIITTAFATVDVAVDAMKKGADEFLTKPFNLSALSVTLRRVHAE
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHH
RSPKSPLDERKHDQIFSALSNPIRRSVIKQLKIHRKMKFMDLCRVVGIEDHTKFNFHLKQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LVNSGLVIKEDGRIYSLTEQGQQVHSSML
HHHCCCEEECCCCEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
TLKLLLAEDDTELREVLVEALTLESFQVVACDNAEDALDIASEQHFDLALFDVVMTGMT
EEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHCCH
GIEALSTLRRQHPNIGIIITTAFATVDVAVDAMKKGADEFLTKPFNLSALSVTLRRVHAE
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHH
RSPKSPLDERKHDQIFSALSNPIRRSVIKQLKIHRKMKFMDLCRVVGIEDHTKFNFHLKQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LVNSGLVIKEDGRIYSLTEQGQQVHSSML
HHHCCCEEECCCCEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]