Click here to switch to the map view.

The map label for this gene is lldP [C]

Identifier: 156976318

GI number: 156976318

Start: 325139

End: 327001

Strand: Reverse

Name: lldP [C]

Synonym: VIBHAR_05091

Alternate gene names: 156976318

Gene position: 327001-325139 (Counterclockwise)

Preceding gene: 156976321

Following gene: 156976316

Centisome position: 14.84

GC content: 50.19

Gene sequence:

>1863_bases
ATGAGTGAAACCCTACTTGCCCTTGTGGCGTTTTCGCCAATAGTTGTCGCCGCCATATTATTGGTTGGTCTCAACTGGCC
TGCTAAAAAAGCCATGCCTATTGCGTTCGGTCTAACCGTCGCTATCGCCCTAATGTTTTGGGATATGTCAGCTACTCGCG
TACTGGCGTCTGTCTTTCAAGGATTAGGCATTACCGTCTCTGTTCTATGGATCGTGTTTGGTGCCATCTTCTTGCTCAAC
ACTTTAAAACACACTGGCGCGATCACCACGATTCGCAATGGGTTTACTGATATTTCAGCCGACCGTCGCGTTCAAGCCAT
CATCATCGCTTGGTGTTTCGGCTCATTCATTGAGGGCGCATCTGGCTTCGGTACACCTGCTGCTATCGCCGCTCCTCTAT
TGGTCGCCATTGGCTTCCCTGCGCTCGCAGCGGTACTGATGGGCATGATGATCCAATCTACACCAGTATCTTTCGGTGCG
GTTGGGACACCAATCATCGTAGGAGTGAACAAAGGTTTAGATACGCACAACATTGGTGAAGCACTGGTTGCTCATGGCTC
AACATGGGAAGCGTACCTACAGCAAATCACCGCAAGCGTAGCCATGATTCACGCAACGGTTGGTACTCTCATTCCTGTAC
TCATGGCAATGATGCTGACTCGATTCTTTGGTAAGAATAAGAGCTGGAGTGAAGGCCTAGACATCCTACCTTTCGCGCTA
TTCGCAGGCGTTGCCTTCACCGTTCCTTATGCACTAACAGGTGTGTTCCTAGGTGCTGAGTTCCCATCACTCATTGGTGG
TCTAGTGGGTCTGGCGATTGTAGTTACTGCGGCGAAGAAAGGTTTCCTCGTACCAAAAACCAAATGGGACTTCGAGAGCG
AAGATAAATGGCCAGCAGAATGGCTCGGTTCTCTAAAGATCAATCTGGATGACACCCCAGGTAGACCAATGAGCCTAACC
AAGGCTTGGGCACCTTACGTAATGCTAGCGGTTATCCTAGTGGCAAGTCGCGTAAGCCCTGAGTTTAAAGGCCTACTCAA
GAGCGTAAGCCTATCGTTTGGTAATATTCTTGGCGAAACAGGCATCAGCACAGCAATTCAACCTTTATATCTTCCGGGTG
GCATCTTAGTCTTCGTAGCGTTACTTGCGGTTCTTCTACAAGGTGGCGGCGCTAAGTCACTAGGCAAAGCATTTGGCGAA
TCAAGCAAGACACTGATCGGTGCAGGTTTCGTTCTTGTGTTCACTATCCCTATGGTTCGCATCTTTATTAACTCAGGTGT
TAACGGCGCCGAGCTAGCAAGTATGCCTGTAACGACAGCGAACTTTGCAGCAGACCTCGTTGGCTCAGCATTCCCGGCGT
TGAGTGCTACTGTTGGTGCCCTTGGTGCATTCATCGCCGGCTCTAATACCGTGTCGAATATGATGTTCAGCCAGTTCCAG
TTCGAAGTGGCGCAGACACTGACTATCTCAAGTGCCATTGTGGTTGCCCTTCAAGCGGTTGGTGCGGCTGCGGGTAACAT
GATTGCCATCCACAACGTTGTGGCGGCCTCTGCAACAGTTGGCCTGCTAGGACGAGAAGGCGCAACCCTTCGCAAGACCA
TTGTTCTACTACTTGGTGGTCGCAGGCATCATCGGTCTGATTCTGATTTACGGATTCCAAATCACCGACGCTTTAATGAA
GTAACACTTACGCAGGGTCTCCCCCGCCCTGCACTTTCTCTGGCACAGCGGTCAGCACTACTACCCCGACTTTTGGTGTG
GCTTGCTGCATCAATCCCCCGACCGGTGTGTCAGTCTTTTTCAGTGCAGATAATTGATTGTTCCGTGTATGAAATGTCCC
ACAGCTCAATCACTTATCTATAA

Upstream 100 bases:

>100_bases
ATAAAGGGGTAAATTCACGCCAAATTAACAAAACCATTACAACAAAAATCATCTCAACAGCATAAAGCGGTTCGAGAAGT
CAGCGTACGAGGATGTACCA

Downstream 100 bases:

>100_bases
TACTCTAATTCTGACGTCGACTGCCGAAAGGATGGCAGTCAGTGAAACACTGACAGAGCAGGTGCTCATTGACTCAGGAC
GCAATCTTAGAATAACAGCT

Product: L-lactate permease Psort location

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MSETLLALVAFSPIVVAAILLVGLNWPAKKAMPIAFGLTVAIALMFWDMSATRVLASVFQGLGITVSVLWIVFGAIFLLN
TLKHTGAITTIRNGFTDISADRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA
VGTPIIVGVNKGLDTHNIGEALVAHGSTWEAYLQQITASVAMIHATVGTLIPVLMAMMLTRFFGKNKSWSEGLDILPFAL
FAGVAFTVPYALTGVFLGAEFPSLIGGLVGLAIVVTAAKKGFLVPKTKWDFESEDKWPAEWLGSLKINLDDTPGRPMSLT
KAWAPYVMLAVILVASRVSPEFKGLLKSVSLSFGNILGETGISTAIQPLYLPGGILVFVALLAVLLQGGGAKSLGKAFGE
SSKTLIGAGFVLVFTIPMVRIFINSGVNGAELASMPVTTANFAADLVGSAFPALSATVGALGAFIAGSNTVSNMMFSQFQ
FEVAQTLTISSAIVVALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTIVLLLGGRRHHRSDSDLRIPNHRRFNE
VTLTQGLPRPALSLAQRSALLPRLLVWLAASIPRPVCQSFSVQIIDCSVYEMSHSSITYL

Sequences:

>Translated_620_residues
MSETLLALVAFSPIVVAAILLVGLNWPAKKAMPIAFGLTVAIALMFWDMSATRVLASVFQGLGITVSVLWIVFGAIFLLN
TLKHTGAITTIRNGFTDISADRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGA
VGTPIIVGVNKGLDTHNIGEALVAHGSTWEAYLQQITASVAMIHATVGTLIPVLMAMMLTRFFGKNKSWSEGLDILPFAL
FAGVAFTVPYALTGVFLGAEFPSLIGGLVGLAIVVTAAKKGFLVPKTKWDFESEDKWPAEWLGSLKINLDDTPGRPMSLT
KAWAPYVMLAVILVASRVSPEFKGLLKSVSLSFGNILGETGISTAIQPLYLPGGILVFVALLAVLLQGGGAKSLGKAFGE
SSKTLIGAGFVLVFTIPMVRIFINSGVNGAELASMPVTTANFAADLVGSAFPALSATVGALGAFIAGSNTVSNMMFSQFQ
FEVAQTLTISSAIVVALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTIVLLLGGRRHHRSDSDLRIPNHRRFNE
VTLTQGLPRPALSLAQRSALLPRLLVWLAASIPRPVCQSFSVQIIDCSVYEMSHSSITYL
>Mature_619_residues
SETLLALVAFSPIVVAAILLVGLNWPAKKAMPIAFGLTVAIALMFWDMSATRVLASVFQGLGITVSVLWIVFGAIFLLNT
LKHTGAITTIRNGFTDISADRRVQAIIIAWCFGSFIEGASGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGAV
GTPIIVGVNKGLDTHNIGEALVAHGSTWEAYLQQITASVAMIHATVGTLIPVLMAMMLTRFFGKNKSWSEGLDILPFALF
AGVAFTVPYALTGVFLGAEFPSLIGGLVGLAIVVTAAKKGFLVPKTKWDFESEDKWPAEWLGSLKINLDDTPGRPMSLTK
AWAPYVMLAVILVASRVSPEFKGLLKSVSLSFGNILGETGISTAIQPLYLPGGILVFVALLAVLLQGGGAKSLGKAFGES
SKTLIGAGFVLVFTIPMVRIFINSGVNGAELASMPVTTANFAADLVGSAFPALSATVGALGAFIAGSNTVSNMMFSQFQF
EVAQTLTISSAIVVALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTIVLLLGGRRHHRSDSDLRIPNHRRFNEV
TLTQGLPRPALSLAQRSALLPRLLVWLAASIPRPVCQSFSVQIIDCSVYEMSHSSITYL

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=565, Percent_Identity=27.787610619469, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789347, Length=560, Percent_Identity=28.0357142857143, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 65098; Mature: 64966

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETLLALVAFSPIVVAAILLVGLNWPAKKAMPIAFGLTVAIALMFWDMSATRVLASVFQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GLGITVSVLWIVFGAIFLLNTLKHTGAITTIRNGFTDISADRRVQAIIIAWCFGSFIEGA
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SGFGTPAAIAAPLLVAIGFPALAAVLMGMMIQSTPVSFGAVGTPIIVGVNKGLDTHNIGE
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHH
ALVAHGSTWEAYLQQITASVAMIHATVGTLIPVLMAMMLTRFFGKNKSWSEGLDILPFAL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHH
FAGVAFTVPYALTGVFLGAEFPSLIGGLVGLAIVVTAAKKGFLVPKTKWDFESEDKWPAE
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
WLGSLKINLDDTPGRPMSLTKAWAPYVMLAVILVASRVSPEFKGLLKSVSLSFGNILGET
HHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
GISTAIQPLYLPGGILVFVALLAVLLQGGGAKSLGKAFGESSKTLIGAGFVLVFTIPMVR
CHHHHCCHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
IFINSGVNGAELASMPVTTANFAADLVGSAFPALSATVGALGAFIAGSNTVSNMMFSQFQ
HHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FEVAQTLTISSAIVVALQAVGAAAGNMIAIHNVVAASATVGLLGREGATLRKTIVLLLGG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
RRHHRSDSDLRIPNHRRFNEVTLTQGLPRPALSLAQRSALLPRLLVWLAASIPRPVCQSF
CCCCCCCCCCCCCCCCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
SVQIIDCSVYEMSHSSITYL
CEEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
SETLLALVAFSPIVVAAILLVGLNWPAKKAMPIAFGLTVAIALMFWDMSATRVLASVFQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH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CEEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]