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The map label for this gene is 156976100

Identifier: 156976100

GI number: 156976100

Start: 138130

End: 139386

Strand: Reverse

Name: 156976100

Synonym: VIBHAR_04871

Alternate gene names: NA

Gene position: 139386-138130 (Counterclockwise)

Preceding gene: 156976103

Following gene: 156976099

Centisome position: 6.32

GC content: 46.38

Gene sequence:

>1257_bases
ATGAATAAGACCATTACGTTACTTAGTGCATTATTACTACCATTAAATCTTGCTCACGCAGCCGACTCATCAGAGCCTTC
TTACCAGCTAAATGCCTCAGAAGTGAGAAGCGCACAACAAAAGCAAACATACACCTACGTACGATGCTGGTATCGAACTA
GTTATTCACATGATGACCCAGAAACGGACTGGGAGTGGGCAGAAAATCCAGATGGCAGTTATTTCAATATCGAAGGCTAT
TGGTGGAACGCACTCTCGTTTAAAAACATGTTCTATACCAATACATCACAAAGCGTGATCAAGCAGCGCTGTGAACAAAC
ACTCGATCTTGCGAACGAAAATGCGGACATTACCTACTTCGCTGCCGATAACCGTTGGTCATACAACCACTCGATTTGGA
GTAATGATCCTGTGATGCAGCCAGATCAAATCAACAAGGTCGTGGCATTGGGTGACAGCTTATCGGATACCGGGAACATC
TTTAACGCATCACAATGGCGATTCCCGAATCCAAACAGCTGGTTCTTAGGGCATTTCTCTAACGGGTTTGTATGGACAGA
ATACATTGCTCAAGCGAAGAATTTACCGCTATACAACTGGGCGGTGGGTGGCGCTGCTGGCGAAAATCAATACATCGCGC
TAACGGGCGTTGGAAAGCAAGTCTCTTCTTACCTTGCTTATATGCAGCTGGCGAAAAACTACAACCCTGCCAATACCCTG
TTCACCCTTGAGTTTGGATTGAATGACTTCATGAACTACAACCGCAGTGTTCCAGAAGTAAAAGCAGATTATTCGGAGGC
CTTGATAAAACTGAGTGATGCTGGCGCAAGAAACTTCTTACTCATGACCCTACCTGACGCGACCTATGCGCCTCAGTTCA
AATATTCTAGCCAAGAAGAAATCGACACAATCCGTGCGAAAATCCTTGAGATGAACGAATTTATCAAAGCGCAGGCAGCT
TACTACACTGCACAGGGGCTCAACATTACGTTGCACGACACCCATGCACTCTTTGCTAGCTTGACAGCTAACCCTGAGCA
ACATGGCTTCAGTAACGCAACGGAAGCATGCCAAGACATCAACCGCTCGTCTGCTGCTGATTACTTGTACAAACATTCGC
TGCGTTCTGAGTGTGCGTCCGTTGGTTCAGATAAATTTGTATTCTGGGATGTGACCCACCCGACCACAGCAACGCATCGC
TACGTGGCTGAGGATATGCTAGAAAGCAGCAACCAGCTATCGAACCATCCGTTCTAA

Upstream 100 bases:

>100_bases
TTAGATATTTGACTGAATTGCGTATTTACCCAGAATGAGGAGAGTTGATGAGATAACCTCTCATCTAAATCATGAAAATT
ATCATTAAAGAGAGTGAATC

Downstream 100 bases:

>100_bases
ATTTCCCTTAAATGGATATTTTAAAGGAGAGGTGAATTAACGGTTACCAATTTACTATAATGCCGATCGGTTTAGAGACT
TGAATGATCTTGGGATCGTA

Product: lipolytic enzyme

Products: NA

Alternate protein names: TL; Atypical phospholipase; Lecithin-dependent hemolysin; LDH; Lysophospholipase; Phospholipase A2 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNKTITLLSALLLPLNLAHAADSSEPSYQLNASEVRSAQQKQTYTYVRCWYRTSYSHDDPETDWEWAENPDGSYFNIEGY
WWNALSFKNMFYTNTSQSVIKQRCEQTLDLANENADITYFAADNRWSYNHSIWSNDPVMQPDQINKVVALGDSLSDTGNI
FNASQWRFPNPNSWFLGHFSNGFVWTEYIAQAKNLPLYNWAVGGAAGENQYIALTGVGKQVSSYLAYMQLAKNYNPANTL
FTLEFGLNDFMNYNRSVPEVKADYSEALIKLSDAGARNFLLMTLPDATYAPQFKYSSQEEIDTIRAKILEMNEFIKAQAA
YYTAQGLNITLHDTHALFASLTANPEQHGFSNATEACQDINRSSAADYLYKHSLRSECASVGSDKFVFWDVTHPTTATHR
YVAEDMLESSNQLSNHPF

Sequences:

>Translated_418_residues
MNKTITLLSALLLPLNLAHAADSSEPSYQLNASEVRSAQQKQTYTYVRCWYRTSYSHDDPETDWEWAENPDGSYFNIEGY
WWNALSFKNMFYTNTSQSVIKQRCEQTLDLANENADITYFAADNRWSYNHSIWSNDPVMQPDQINKVVALGDSLSDTGNI
FNASQWRFPNPNSWFLGHFSNGFVWTEYIAQAKNLPLYNWAVGGAAGENQYIALTGVGKQVSSYLAYMQLAKNYNPANTL
FTLEFGLNDFMNYNRSVPEVKADYSEALIKLSDAGARNFLLMTLPDATYAPQFKYSSQEEIDTIRAKILEMNEFIKAQAA
YYTAQGLNITLHDTHALFASLTANPEQHGFSNATEACQDINRSSAADYLYKHSLRSECASVGSDKFVFWDVTHPTTATHR
YVAEDMLESSNQLSNHPF
>Mature_418_residues
MNKTITLLSALLLPLNLAHAADSSEPSYQLNASEVRSAQQKQTYTYVRCWYRTSYSHDDPETDWEWAENPDGSYFNIEGY
WWNALSFKNMFYTNTSQSVIKQRCEQTLDLANENADITYFAADNRWSYNHSIWSNDPVMQPDQINKVVALGDSLSDTGNI
FNASQWRFPNPNSWFLGHFSNGFVWTEYIAQAKNLPLYNWAVGGAAGENQYIALTGVGKQVSSYLAYMQLAKNYNPANTL
FTLEFGLNDFMNYNRSVPEVKADYSEALIKLSDAGARNFLLMTLPDATYAPQFKYSSQEEIDTIRAKILEMNEFIKAQAA
YYTAQGLNITLHDTHALFASLTANPEQHGFSNATEACQDINRSSAADYLYKHSLRSECASVGSDKFVFWDVTHPTTATHR
YVAEDMLESSNQLSNHPF

Specific function: Phospholipase hydrolyzing both fatty acid esters of phospholipid, i.e., it hydrolyzes phosphatidylcholine (PC) to lysophosphatidylcholine (LPC) and then LPC to glycerophosphorylcholine (GPC) [H]

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: NA

Molecular weight: Translated: 47433; Mature: 47433

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01098 LIPASE_GDSL_SER ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTITLLSALLLPLNLAHAADSSEPSYQLNASEVRSAQQKQTYTYVRCWYRTSYSHDDP
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHEEEEEEEEECCCCCCCC
ETDWEWAENPDGSYFNIEGYWWNALSFKNMFYTNTSQSVIKQRCEQTLDLANENADITYF
CCCCCCCCCCCCCEEEECEEEECCEEECCEEEECCHHHHHHHHHHHHHHHCCCCCCEEEE
AADNRWSYNHSIWSNDPVMQPDQINKVVALGDSLSDTGNIFNASQWRFPNPNSWFLGHFS
EECCEEECCCCCCCCCCCCCHHHHCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECC
NGFVWTEYIAQAKNLPLYNWAVGGAAGENQYIALTGVGKQVSSYLAYMQLAKNYNPANTL
CCEEHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEE
FTLEFGLNDFMNYNRSVPEVKADYSEALIKLSDAGARNFLLMTLPDATYAPQFKYSSQEE
EEEEECCHHHHHCCCCCCCHHHCHHHHHEEEECCCCCEEEEEECCCCCCCCCCCCCCHHH
IDTIRAKILEMNEFIKAQAAYYTAQGLNITLHDTHALFASLTANPEQHGFSNATEACQDI
HHHHHHHHHHHHHHHHHHHHEEEECCCEEEEECHHHHHHHHCCCCHHCCCCHHHHHHHHC
NRSSAADYLYKHSLRSECASVGSDKFVFWDVTHPTTATHRYVAEDMLESSNQLSNHPF
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNKTITLLSALLLPLNLAHAADSSEPSYQLNASEVRSAQQKQTYTYVRCWYRTSYSHDDP
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHEEEEEEEEECCCCCCCC
ETDWEWAENPDGSYFNIEGYWWNALSFKNMFYTNTSQSVIKQRCEQTLDLANENADITYF
CCCCCCCCCCCCCEEEECEEEECCEEECCEEEECCHHHHHHHHHHHHHHHCCCCCCEEEE
AADNRWSYNHSIWSNDPVMQPDQINKVVALGDSLSDTGNIFNASQWRFPNPNSWFLGHFS
EECCEEECCCCCCCCCCCCCHHHHCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECC
NGFVWTEYIAQAKNLPLYNWAVGGAAGENQYIALTGVGKQVSSYLAYMQLAKNYNPANTL
CCEEHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEE
FTLEFGLNDFMNYNRSVPEVKADYSEALIKLSDAGARNFLLMTLPDATYAPQFKYSSQEE
EEEEECCHHHHHCCCCCCCHHHCHHHHHEEEECCCCCEEEEEECCCCCCCCCCCCCCHHH
IDTIRAKILEMNEFIKAQAAYYTAQGLNITLHDTHALFASLTANPEQHGFSNATEACQDI
HHHHHHHHHHHHHHHHHHHHEEEECCCEEEEECHHHHHHHHCCCCHHCCCCHHHHHHHHC
NRSSAADYLYKHSLRSECASVGSDKFVFWDVTHPTTATHRYVAEDMLESSNQLSNHPF
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3508495; 12620739; 1791426 [H]