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The map label for this gene is rio2 [H]

Identifier: 156938180

GI number: 156938180

Start: 1254922

End: 1255809

Strand: Reverse

Name: rio2 [H]

Synonym: Igni_1393

Alternate gene names: 156938180

Gene position: 1255809-1254922 (Counterclockwise)

Preceding gene: 156938181

Following gene: 156938179

Centisome position: 96.78

GC content: 50.9

Gene sequence:

>888_bases
TTGAACCTGAAGGAGATATATGCTCAACTGACAGAGGACGACATAAAGGTTCTCAAGGCAATTGAGAGGAGACTTAAGAC
GCATGAGTTCGTCCCGGTGGAGATCCTCGAGAAGGAGACCAAACTCCCCCTTCACAGGTTGGAGAGGAGTCTCTACCACC
TCAACAAGCTCAAGCTCTTGAGGAGGATGAGCGGGAGCAGTTTGGGATACAGGCTCACCATTTTGGCCTACGACGTCTTG
GCCATTCATACCCTCATGAAGAGGGGGGTCTTAGCCGAGATAGGCGACAAGATAGGGGTCGGGAAGGAGAGCGACGTATA
TCTCGGAATAGCCCCCGGCGGAAAGAGGCTTGCGGTTAAGTTTCACAGGGTCGGAAGGAAGAGCTTTAGGCACGTGGCAA
GGAACAGGCCTTACAAATTGGAGGACAGTTGGCTCCTCCAGTCTAAGGTGTCGGCTAGCAGGGAGTTCGCGGCACTCAAA
GAGTTATATCCTAGGGGCGCGAAGGTTCCCAAACCTGTTGATAAGAGTAGGCACGTAGTGGTCACCGAACTGATAGAGGG
GGCCGTCGAACTTTACACCAAGCCCGACATCCCCGACCCTTTAAAGGCACTTGAGGACGTGCTGGTTACAATAGAAATCG
CGTACAAAGACGTAGGTATAGTGCACGGCGACTTGAGCGAGTATAACATAATAGTAGTTCCCTCTACCTCTGAGGCCTTC
ATAATAGATTGGCCACAGTACGTAGAGAAAGATAGCCCGCTAGCTGAGAGGTTGTTGAGGAGGGACGTAGAGTACGTGGT
AAGATTTTTTAAGAAAGTATACGGTATCCCCTTAGATGTTGATGAGGTGGTCAGAAGGCTCAAAGAATTGCCCAGTGGTA
GCGGTTGA

Upstream 100 bases:

>100_bases
GCTGTGGGTTACAGCGACGTCCCGAAGACTCTGGAGAACTCCAAGGTAAAGGTCACGGAAAACTTACAACAATTCCTAGA
GGCGCTCTCCGGGGAGCCAG

Downstream 100 bases:

>100_bases
CCTAGAGCCGGGCTCTCCGCCGGGGATTAAGGGAAAGTTCCACTTGGTGTTAGTCGACTGCGACGGGAAAGTAATCATAG
ATAAGAGGGTTGACATTAAG

Product: protein of unknown function RIO1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNLKEIYAQLTEDDIKVLKAIERRLKTHEFVPVEILEKETKLPLHRLERSLYHLNKLKLLRRMSGSSLGYRLTILAYDVL
AIHTLMKRGVLAEIGDKIGVGKESDVYLGIAPGGKRLAVKFHRVGRKSFRHVARNRPYKLEDSWLLQSKVSASREFAALK
ELYPRGAKVPKPVDKSRHVVVTELIEGAVELYTKPDIPDPLKALEDVLVTIEIAYKDVGIVHGDLSEYNIIVVPSTSEAF
IIDWPQYVEKDSPLAERLLRRDVEYVVRFFKKVYGIPLDVDEVVRRLKELPSGSG

Sequences:

>Translated_295_residues
MNLKEIYAQLTEDDIKVLKAIERRLKTHEFVPVEILEKETKLPLHRLERSLYHLNKLKLLRRMSGSSLGYRLTILAYDVL
AIHTLMKRGVLAEIGDKIGVGKESDVYLGIAPGGKRLAVKFHRVGRKSFRHVARNRPYKLEDSWLLQSKVSASREFAALK
ELYPRGAKVPKPVDKSRHVVVTELIEGAVELYTKPDIPDPLKALEDVLVTIEIAYKDVGIVHGDLSEYNIIVVPSTSEAF
IIDWPQYVEKDSPLAERLLRRDVEYVVRFFKKVYGIPLDVDEVVRRLKELPSGSG
>Mature_295_residues
MNLKEIYAQLTEDDIKVLKAIERRLKTHEFVPVEILEKETKLPLHRLERSLYHLNKLKLLRRMSGSSLGYRLTILAYDVL
AIHTLMKRGVLAEIGDKIGVGKESDVYLGIAPGGKRLAVKFHRVGRKSFRHVARNRPYKLEDSWLLQSKVSASREFAALK
ELYPRGAKVPKPVDKSRHVVVTELIEGAVELYTKPDIPDPLKALEDVLVTIEIAYKDVGIVHGDLSEYNIIVVPSTSEAF
IIDWPQYVEKDSPLAERLLRRDVEYVVRFFKKVYGIPLDVDEVVRRLKELPSGSG

Specific function: Unknown

COG id: COG0478

COG function: function code T; RIO-like serine/threonine protein kinase fused to N-terminal HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI229331971, Length=269, Percent_Identity=38.2899628252788, Blast_Score=174, Evalue=6e-44,
Organism=Homo sapiens, GI229331967, Length=269, Percent_Identity=38.2899628252788, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI23510356, Length=212, Percent_Identity=30.188679245283, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32564178, Length=269, Percent_Identity=39.7769516728625, Blast_Score=173, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI115532073, Length=227, Percent_Identity=28.6343612334802, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556977, Length=208, Percent_Identity=24.5192307692308, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324122, Length=276, Percent_Identity=35.1449275362319, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324693, Length=234, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24649986, Length=272, Percent_Identity=36.3970588235294, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24662811, Length=210, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356879, Length=210, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR015285
- InterPro:   IPR000687
- InterPro:   IPR018935 [H]

Pfam domain/function: PF01163 RIO1; PF09202 Rio2_N [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33660; Mature: 33660

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKEIYAQLTEDDIKVLKAIERRLKTHEFVPVEILEKETKLPLHRLERSLYHLNKLKLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RRMSGSSLGYRLTILAYDVLAIHTLMKRGVLAEIGDKIGVGKESDVYLGIAPGGKRLAVK
HHHCCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEHH
FHRVGRKSFRHVARNRPYKLEDSWLLQSKVSASREFAALKELYPRGAKVPKPVDKSRHVV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
VTELIEGAVELYTKPDIPDPLKALEDVLVTIEIAYKDVGIVHGDLSEYNIIVVPSTSEAF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEEHHCCEEECCCCCCEEEEEECCCCEE
IIDWPQYVEKDSPLAERLLRRDVEYVVRFFKKVYGIPLDVDEVVRRLKELPSGSG
EEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNLKEIYAQLTEDDIKVLKAIERRLKTHEFVPVEILEKETKLPLHRLERSLYHLNKLKLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RRMSGSSLGYRLTILAYDVLAIHTLMKRGVLAEIGDKIGVGKESDVYLGIAPGGKRLAVK
HHHCCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEHH
FHRVGRKSFRHVARNRPYKLEDSWLLQSKVSASREFAALKELYPRGAKVPKPVDKSRHVV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
VTELIEGAVELYTKPDIPDPLKALEDVLVTIEIAYKDVGIVHGDLSEYNIIVVPSTSEAF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEEHHCCEEECCCCCCEEEEEECCCCEE
IIDWPQYVEKDSPLAERLLRRDVEYVVRFFKKVYGIPLDVDEVVRRLKELPSGSG
EEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]