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The map label for this gene is nanK [H]

Identifier: 156938148

GI number: 156938148

Start: 1216887

End: 1217798

Strand: Direct

Name: nanK [H]

Synonym: Igni_1361

Alternate gene names: 156938148

Gene position: 1216887-1217798 (Clockwise)

Preceding gene: 156938146

Following gene: 156938149

Centisome position: 93.78

GC content: 54.5

Gene sequence:

>912_bases
GTGGACTACCTTAATAGTGAGGCGTTCGACGAAAGGCCGGTTGGCGTTGCAGACGTCGGGGGCACCAAGACCAGGGTAGC
CTTGTATGAAAACGACTCCTTAAAGGAGCTGGAGGAGTTCCCGACCCCTAAAGAGGAGCCCCTCTGGAAGCCTCTTTGGA
GCTACTTCAAGGATAAAGAAGTCCAAAATATCGTGATAGCTACCATGGGACCCCTAAAGATGAGCGAGGGAAAGGTGGTC
TCTAATCCCCATTCTCAAATTAAAGATCAAGAGGTCGGGAGGCCCTTAATGGAACGCTTGAAGATTCCGGTCTTGGTGAT
CAACGACTGCGTCGCGGGGGCTTACGCGGAGTTCAAGGCGAGGAACGTGGAGAACTTAGTCTACTTAGCCTTTGGCACCG
GAGTGGGGGCCGGCGCCGTCGTAGACGGGAGGCTCTTACTAGGGAGGGAGGGCAACGCCCACGAGGTCGGGCACTTCGTC
ATGTCCTTAGGCCTCGGGTTGAGGTGTGGGTGCGGTAAGACGGACCACGCCGAGGCGGTGTTGGGCGGAAGTAACATAGT
AAACTATTTCAAGAGGGAAGGCTTCGAGGCCCGGAACGCGGCCGAGCTGTTCAACCTTATCAGATCTAACCCAAAGGCCT
TCGAACTTTTCAAGAGGGCTTTGAACTCGTTCGTCAGCTCGGTGATAGCTTTCTACGATCCGGAGGTAGTGGTCCTAGGA
GGGGGCGTGTTTTCAAAGAATAAGAAGGTTTTCTTCTCTGCGCTGGAGGAACTGGAGGACTACTTGTTGTGGGAAGCCCC
GAAAGTCGAAGAAGCCCTCTACGGCGAGCTGAGCCCCCTCTACGGGGCGGGAGCTTTAGGAGTAGAGAGGCCCCAGTGGT
TAATAAAGAAGTTGAGGTATGTGTTCAAGTAG

Upstream 100 bases:

>100_bases
CGGAACACCGGCACGTTGAGCTCCGGACACCAGTATACTTGGAGCTCCCTCTCCCACTTCCTTTTCAAGTCGGGCGGCAC
CCGCGCGGGCGGGAGGCGTT

Downstream 100 bases:

>100_bases
GCCTTTCAGAAACTTTGGGGTTTCGTCGAGAAAGCCTTTAGGGAAGCGGCTTGCCGGTGGTTTTCGTGTGTTCTAACTGC
GGCCACGCGATAAACGTTTA

Product: glucokinase

Products: NA

Alternate protein names: ManNAc kinase; N-acetyl-D-mannosamine kinase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDYLNSEAFDERPVGVADVGGTKTRVALYENDSLKELEEFPTPKEEPLWKPLWSYFKDKEVQNIVIATMGPLKMSEGKVV
SNPHSQIKDQEVGRPLMERLKIPVLVINDCVAGAYAEFKARNVENLVYLAFGTGVGAGAVVDGRLLLGREGNAHEVGHFV
MSLGLGLRCGCGKTDHAEAVLGGSNIVNYFKREGFEARNAAELFNLIRSNPKAFELFKRALNSFVSSVIAFYDPEVVVLG
GGVFSKNKKVFFSALEELEDYLLWEAPKVEEALYGELSPLYGAGALGVERPQWLIKKLRYVFK

Sequences:

>Translated_303_residues
MDYLNSEAFDERPVGVADVGGTKTRVALYENDSLKELEEFPTPKEEPLWKPLWSYFKDKEVQNIVIATMGPLKMSEGKVV
SNPHSQIKDQEVGRPLMERLKIPVLVINDCVAGAYAEFKARNVENLVYLAFGTGVGAGAVVDGRLLLGREGNAHEVGHFV
MSLGLGLRCGCGKTDHAEAVLGGSNIVNYFKREGFEARNAAELFNLIRSNPKAFELFKRALNSFVSSVIAFYDPEVVVLG
GGVFSKNKKVFFSALEELEDYLLWEAPKVEEALYGELSPLYGAGALGVERPQWLIKKLRYVFK
>Mature_303_residues
MDYLNSEAFDERPVGVADVGGTKTRVALYENDSLKELEEFPTPKEEPLWKPLWSYFKDKEVQNIVIATMGPLKMSEGKVV
SNPHSQIKDQEVGRPLMERLKIPVLVINDCVAGAYAEFKARNVENLVYLAFGTGVGAGAVVDGRLLLGREGNAHEVGHFV
MSLGLGLRCGCGKTDHAEAVLGGSNIVNYFKREGFEARNAAELFNLIRSNPKAFELFKRALNSFVSSVIAFYDPEVVVLG
GGVFSKNKKVFFSALEELEDYLLWEAPKVEEALYGELSPLYGAGALGVERPQWLIKKLRYVFK

Specific function: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NanK subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082230, Length=246, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786891, Length=247, Percent_Identity=24.6963562753036, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081733, Length=296, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.60 [H]

Molecular weight: Translated: 33587; Mature: 33587

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYLNSEAFDERPVGVADVGGTKTRVALYENDSLKELEEFPTPKEEPLWKPLWSYFKDKE
CCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHCCCC
VQNIVIATMGPLKMSEGKVVSNPHSQIKDQEVGRPLMERLKIPVLVINDCVAGAYAEFKA
CCEEEEEECCCCCCCCCCEECCCHHHHCHHHCCHHHHHHHCCCEEEECHHHHHHHHHHHH
RNVENLVYLAFGTGVGAGAVVDGRLLLGREGNAHEVGHFVMSLGLGLRCGCGKTDHAEAV
CCCCCEEEEEEECCCCCCCEECCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEE
LGGSNIVNYFKREGFEARNAAELFNLIRSNPKAFELFKRALNSFVSSVIAFYDPEVVVLG
ECCHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GGVFSKNKKVFFSALEELEDYLLWEAPKVEEALYGELSPLYGAGALGVERPQWLIKKLRY
CCEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
VFK
HCC
>Mature Secondary Structure
MDYLNSEAFDERPVGVADVGGTKTRVALYENDSLKELEEFPTPKEEPLWKPLWSYFKDKE
CCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHCCCC
VQNIVIATMGPLKMSEGKVVSNPHSQIKDQEVGRPLMERLKIPVLVINDCVAGAYAEFKA
CCEEEEEECCCCCCCCCCEECCCHHHHCHHHCCHHHHHHHCCCEEEECHHHHHHHHHHHH
RNVENLVYLAFGTGVGAGAVVDGRLLLGREGNAHEVGHFVMSLGLGLRCGCGKTDHAEAV
CCCCCEEEEEEECCCCCCCEECCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEE
LGGSNIVNYFKREGFEARNAAELFNLIRSNPKAFELFKRALNSFVSSVIAFYDPEVVVLG
ECCHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GGVFSKNKKVFFSALEELEDYLLWEAPKVEEALYGELSPLYGAGALGVERPQWLIKKLRY
CCEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
VFK
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA