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The map label for this gene is gch3 [H]

Identifier: 156938139

GI number: 156938139

Start: 1206892

End: 1207536

Strand: Reverse

Name: gch3 [H]

Synonym: Igni_1352

Alternate gene names: 156938139

Gene position: 1207536-1206892 (Counterclockwise)

Preceding gene: 156938144

Following gene: 156938137

Centisome position: 93.06

GC content: 53.18

Gene sequence:

>645_bases
GTGCACAAAGTCGCCAGCGTGGTGTTGGAGGGCTACAGGGAATGGACCGAAAGCTTGGGGGACGATCGCGAGTGGAAGAT
TCAGCTCAAACAGGCGGAAATCGACATGGTTGCGACGAGAGCCGCGAAGGACGTGGGCGCATTCTACATACCAACTAGAA
AAGATGTGCTCTTCTTCGTGCTCAACGGGGTGGAGGACCCCGCGCCCATCTTCGAAGAGGTATCCAAAGTAAGCCCAGTA
CCCATTTCGGTCGTTGTCGGTTGCGGGAGAACTCCCTTGGCCGCTTTGAACTCTCGCGAGACGTGCAAGGTCACGAGCAA
CATAGCTGCTATACACATTGATATAAACTTTTTCAGAACTAGAGACAAGTACTTAGGCTTCGTGGAGTCGGTAGACTTAT
TGGACGACATACTCAAAATAGGGATAGGCTACGGTTCTATAGGTACGTACTTGGGAGGGGACAACATAGTGATGTTCTCG
GACCCCTCGGCGGCGGGAGAGCTCGCGCGCTTGATCTCCTCGTTCTACGACGTGAAGGTGGGCGTTGGAATAGATAAGAC
CCCAAGAGGGGCCTTGGAGCTAGCCGCGAGGGCGTTAAGACTCCTCCGGGAGGACCGGACTTCTAAAGTCATAATATTAA
AGTGA

Upstream 100 bases:

>100_bases
GAAGGGGCCGTCGTCTAGCTTGGTAGGATGCGGGGCTTGGGCCCCCGTGGTCCGGGGTTCAAATCCCCGCGGCCCCACCT
AAAGCCCCAGGGAAGGGTCC

Downstream 100 bases:

>100_bases
TCCCTCCTCGCATTCGGGCGATGAGAGGCGCGCTGGAAGCTGAGAGGTGATGCAATTGGCTACATTTCGAGCCCTATTCC
TTCCATATTAACGAGAAGAA

Product: GTP cyclohydrolase IIA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MHKVASVVLEGYREWTESLGDDREWKIQLKQAEIDMVATRAAKDVGAFYIPTRKDVLFFVLNGVEDPAPIFEEVSKVSPV
PISVVVGCGRTPLAALNSRETCKVTSNIAAIHIDINFFRTRDKYLGFVESVDLLDDILKIGIGYGSIGTYLGGDNIVMFS
DPSAAGELARLISSFYDVKVGVGIDKTPRGALELAARALRLLREDRTSKVIILK

Sequences:

>Translated_214_residues
MHKVASVVLEGYREWTESLGDDREWKIQLKQAEIDMVATRAAKDVGAFYIPTRKDVLFFVLNGVEDPAPIFEEVSKVSPV
PISVVVGCGRTPLAALNSRETCKVTSNIAAIHIDINFFRTRDKYLGFVESVDLLDDILKIGIGYGSIGTYLGGDNIVMFS
DPSAAGELARLISSFYDVKVGVGIDKTPRGALELAARALRLLREDRTSKVIILK
>Mature_214_residues
MHKVASVVLEGYREWTESLGDDREWKIQLKQAEIDMVATRAAKDVGAFYIPTRKDVLFFVLNGVEDPAPIFEEVSKVSPV
PISVVVGCGRTPLAALNSRETCKVTSNIAAIHIDINFFRTRDKYLGFVESVDLLDDILKIGIGYGSIGTYLGGDNIVMFS
DPSAAGELARLISSFYDVKVGVGIDKTPRGALELAARALRLLREDRTSKVIILK

Specific function: Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity [H]

COG id: COG2429

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal-type GTP cyclohydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007839
- ProDom:   PD313320 [H]

Pfam domain/function: PF05165 GGDN [H]

EC number: =3.5.4.29 [H]

Molecular weight: Translated: 23505; Mature: 23505

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKVASVVLEGYREWTESLGDDREWKIQLKQAEIDMVATRAAKDVGAFYIPTRKDVLFFV
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCEEECCCCCCEEEEE
LNGVEDPAPIFEEVSKVSPVPISVVVGCGRTPLAALNSRETCKVTSNIAAIHIDINFFRT
ECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHCCCCCEEEEECCEEEEEEEEEEEEC
RDKYLGFVESVDLLDDILKIGIGYGSIGTYLGGDNIVMFSDPSAAGELARLISSFYDVKV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCEEEEECCCCHHHHHHHHHHHHHCEEE
GVGIDKTPRGALELAARALRLLREDRTSKVIILK
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MHKVASVVLEGYREWTESLGDDREWKIQLKQAEIDMVATRAAKDVGAFYIPTRKDVLFFV
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCEEECCCCCCEEEEE
LNGVEDPAPIFEEVSKVSPVPISVVVGCGRTPLAALNSRETCKVTSNIAAIHIDINFFRT
ECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHCCCCCEEEEECCEEEEEEEEEEEEC
RDKYLGFVESVDLLDDILKIGIGYGSIGTYLGGDNIVMFSDPSAAGELARLISSFYDVKV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCEEEEECCCCHHHHHHHHHHHHHCEEE
GVGIDKTPRGALELAARALRLLREDRTSKVIILK
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]