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The map label for this gene is aroA [H]

Identifier: 156938075

GI number: 156938075

Start: 1144173

End: 1145504

Strand: Direct

Name: aroA [H]

Synonym: Igni_1288

Alternate gene names: 156938075

Gene position: 1144173-1145504 (Clockwise)

Preceding gene: 156938073

Following gene: 156938076

Centisome position: 88.18

GC content: 64.19

Gene sequence:

>1332_bases
ATGCTGAATACTCCGGCACTTACGGACGGCCCTTGTGAGGGCAAGAGGAACTTGAGGGTGAGGGTAGAGCCGTCGACGCC
GGAGGGCTCCGTAGAGGCGCCGCCGAGCAAGAGCTGGGCCCAGAGGGCAGCCTTCTTGGCCCTCTTGGCCGAGGGGAGGA
GCTCCTTTCGGAGGGTGCCCGAGTCAGACGACGTGCTCGCCTCGCTGGAGGCGGTCCGGGCTTTCGGGGCGAAGGTGGAG
GCGAAGGGAGGGGAGGTTGCGATAGAGGGAGGGGAGGTCAAGGTACCCGAGGACGTAATCAACATGAGGGGCTCCGGCAC
GGGGGCGCGGATAGCGATAGCCGTGGGGACTTTGGTGCCTAAAGGCTTCGGGGTAGTAGTAACGGGTAACGCCAGCCTCC
GCAGGAGGCCCATGACTCCGGTCGTGGAAGTGATGAACGCCTTGGGGGCGGAGGTAGTCAGCTTGAGGGGGGGACTCCTC
CCGGTCGTGAGCTTCGGGGGGCTCCCGGGCGGGGAGGCGGAGGTGGACGGGAGCGTAACCAGCCAACACGTGACGGCGGC
TCTAATAGCTTCCACCAAGAGCGAGAGGGGGGCAAAAATAACCGTTAAGAACGCCGTCTCAAGGGGCTATATCGCCTTAA
CGGAGAGGGTGATGAGGCTCTTCGGGGCCAAGGTCAAGTGCGACGCGAAGTACTCTTACTGCGAAGTGGAGCCCTCGGAG
CTGAAAGCCGTAAGGTCTGAAGTGCCCGGGGACTACGCGCTGGCCGCCTTCCCGGCCGCCCTGGCGGTGGTGAGCGGGGG
CGAGGTGAAGGTGGGCCCCCTGCCGCCCCCGGAGAGCGGCCCGGGGGACCACAGGCTGGTAGACTACCTAAGGAAGTTCG
GGGTGGAAGTCAGCTACTCCGACGGCTACTTGCGCGTAGAAGGGAGCGTGAGGCCGAAGGGGACTCGAGTAAACTTGAAG
GACGAGCCGGACCTAGCCCTCCCCCTGGCGGCCGTGGCGGCCGTCAGCAAGGGAGAGAGCGTGTTGGCGGGCCTCTCTCA
CTTAGTATATAAGGAGTCAAACAGGATAGAGACGATATTGCAAACGCTCAAGTGTTTCGGCGTGAGCGCGCGCGTCGACG
GGCCGAGCATAAGGGTCTTGGGAACGGAGTCGCTAAGGCCTTGCAGACTTAAGTGCCCGGACGACCACCGGATAGCGATG
CTCGCCGCAGTGTTGGGGTCTGCCGCGGGGGCCGTTATAGAGTCCGCGGAGTGCGTCAACAAGAGCTGGCCCGGGTTCTG
GGACGCGCTGAGCTCTCTGGGGGTGAAGGTCTATGTGGAGGGTCGCCGCTAA

Upstream 100 bases:

>100_bases
TCTTGGACGGGGAACAGCCGCCTTATGCCCCTCTCCTCCAACCACTCCTTTAACCCTAACCTCGCTCCCTCGGGGTTCTG
GGCCCTCAAGCGTTAAAGTA

Downstream 100 bases:

>100_bases
GAGGGGGTACTTGAGCATAAGGGGAGAGGACGTGTACGCCGTGGTCGACCCCTCGGAGCTGCCGGAGGACTTAATAGACA
TAGACTTCGTCATTCTAACC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MLNTPALTDGPCEGKRNLRVRVEPSTPEGSVEAPPSKSWAQRAAFLALLAEGRSSFRRVPESDDVLASLEAVRAFGAKVE
AKGGEVAIEGGEVKVPEDVINMRGSGTGARIAIAVGTLVPKGFGVVVTGNASLRRRPMTPVVEVMNALGAEVVSLRGGLL
PVVSFGGLPGGEAEVDGSVTSQHVTAALIASTKSERGAKITVKNAVSRGYIALTERVMRLFGAKVKCDAKYSYCEVEPSE
LKAVRSEVPGDYALAAFPAALAVVSGGEVKVGPLPPPESGPGDHRLVDYLRKFGVEVSYSDGYLRVEGSVRPKGTRVNLK
DEPDLALPLAAVAAVSKGESVLAGLSHLVYKESNRIETILQTLKCFGVSARVDGPSIRVLGTESLRPCRLKCPDDHRIAM
LAAVLGSAAGAVIESAECVNKSWPGFWDALSSLGVKVYVEGRR

Sequences:

>Translated_443_residues
MLNTPALTDGPCEGKRNLRVRVEPSTPEGSVEAPPSKSWAQRAAFLALLAEGRSSFRRVPESDDVLASLEAVRAFGAKVE
AKGGEVAIEGGEVKVPEDVINMRGSGTGARIAIAVGTLVPKGFGVVVTGNASLRRRPMTPVVEVMNALGAEVVSLRGGLL
PVVSFGGLPGGEAEVDGSVTSQHVTAALIASTKSERGAKITVKNAVSRGYIALTERVMRLFGAKVKCDAKYSYCEVEPSE
LKAVRSEVPGDYALAAFPAALAVVSGGEVKVGPLPPPESGPGDHRLVDYLRKFGVEVSYSDGYLRVEGSVRPKGTRVNLK
DEPDLALPLAAVAAVSKGESVLAGLSHLVYKESNRIETILQTLKCFGVSARVDGPSIRVLGTESLRPCRLKCPDDHRIAM
LAAVLGSAAGAVIESAECVNKSWPGFWDALSSLGVKVYVEGRR
>Mature_443_residues
MLNTPALTDGPCEGKRNLRVRVEPSTPEGSVEAPPSKSWAQRAAFLALLAEGRSSFRRVPESDDVLASLEAVRAFGAKVE
AKGGEVAIEGGEVKVPEDVINMRGSGTGARIAIAVGTLVPKGFGVVVTGNASLRRRPMTPVVEVMNALGAEVVSLRGGLL
PVVSFGGLPGGEAEVDGSVTSQHVTAALIASTKSERGAKITVKNAVSRGYIALTERVMRLFGAKVKCDAKYSYCEVEPSE
LKAVRSEVPGDYALAAFPAALAVVSGGEVKVGPLPPPESGPGDHRLVDYLRKFGVEVSYSDGYLRVEGSVRPKGTRVNLK
DEPDLALPLAAVAAVSKGESVLAGLSHLVYKESNRIETILQTLKCFGVSARVDGPSIRVLGTESLRPCRLKCPDDHRIAM
LAAVLGSAAGAVIESAECVNKSWPGFWDALSSLGVKVYVEGRR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=416, Percent_Identity=27.1634615384615, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320332, Length=467, Percent_Identity=28.6937901498929, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46507; Mature: 46507

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTPALTDGPCEGKRNLRVRVEPSTPEGSVEAPPSKSWAQRAAFLALLAEGRSSFRRVP
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ESDDVLASLEAVRAFGAKVEAKGGEVAIEGGEVKVPEDVINMRGSGTGARIAIAVGTLVP
CCCHHHHHHHHHHHHCCEEECCCCEEEEECCCEECCHHHHHCCCCCCCCEEEEEEECCCC
KGFGVVVTGNASLRRRPMTPVVEVMNALGAEVVSLRGGLLPVVSFGGLPGGEAEVDGSVT
CCCEEEEECCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCCCCCCCH
SQHVTAALIASTKSERGAKITVKNAVSRGYIALTERVMRLFGAKVKCDAKYSYCEVEPSE
HHHHHHHHHHHCCCCCCCEEEEEHHCCCCHHHHHHHHHHHHCCCEEECCCCCEEECCHHH
LKAVRSEVPGDYALAAFPAALAVVSGGEVKVGPLPPPESGPGDHRLVDYLRKFGVEVSYS
HHHHHHHCCCCHHHHHHHHHHHEECCCCEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEC
DGYLRVEGSVRPKGTRVNLKDEPDLALPLAAVAAVSKGESVLAGLSHLVYKESNRIETIL
CCEEEEECCCCCCCCEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
QTLKCFGVSARVDGPSIRVLGTESLRPCRLKCPDDHRIAMLAAVLGSAAGAVIESAECVN
HHHHHCCCEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
KSWPGFWDALSSLGVKVYVEGRR
CCCCCHHHHHHHCCEEEEEECCC
>Mature Secondary Structure
MLNTPALTDGPCEGKRNLRVRVEPSTPEGSVEAPPSKSWAQRAAFLALLAEGRSSFRRVP
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ESDDVLASLEAVRAFGAKVEAKGGEVAIEGGEVKVPEDVINMRGSGTGARIAIAVGTLVP
CCCHHHHHHHHHHHHCCEEECCCCEEEEECCCEECCHHHHHCCCCCCCCEEEEEEECCCC
KGFGVVVTGNASLRRRPMTPVVEVMNALGAEVVSLRGGLLPVVSFGGLPGGEAEVDGSVT
CCCEEEEECCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCCCCCCCH
SQHVTAALIASTKSERGAKITVKNAVSRGYIALTERVMRLFGAKVKCDAKYSYCEVEPSE
HHHHHHHHHHHCCCCCCCEEEEEHHCCCCHHHHHHHHHHHHCCCEEECCCCCEEECCHHH
LKAVRSEVPGDYALAAFPAALAVVSGGEVKVGPLPPPESGPGDHRLVDYLRKFGVEVSYS
HHHHHHHCCCCHHHHHHHHHHHEECCCCEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEC
DGYLRVEGSVRPKGTRVNLKDEPDLALPLAAVAAVSKGESVLAGLSHLVYKESNRIETIL
CCEEEEECCCCCCCCEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
QTLKCFGVSARVDGPSIRVLGTESLRPCRLKCPDDHRIAMLAAVLGSAAGAVIESAECVN
HHHHHCCCEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
KSWPGFWDALSSLGVKVYVEGRR
CCCCCHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA