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The map label for this gene is yaaI [H]

Identifier: 156937994

GI number: 156937994

Start: 1076477

End: 1077028

Strand: Reverse

Name: yaaI [H]

Synonym: Igni_1207

Alternate gene names: 156937994

Gene position: 1077028-1076477 (Counterclockwise)

Preceding gene: 156937996

Following gene: 156937992

Centisome position: 83.01

GC content: 60.14

Gene sequence:

>552_bases
ATGAAGGCCTTGCTCATAATAGACATGTTAAACGACTTCGTAAACCCTAAGGGCAAGTTGTACGTCCCCAAGTCTGAGAC
TATAATACCCAAGGTGAAGGAGCTTAAGAGGGCCTTCAAGGAGGCCGGGCTGCCGGTGATTTACACCAACGACGCCCACT
TGCCCGGAGTGGACAAGGAGCTCGAGCTCTGGGGCCCCCACGCGGTGGCCAACACTTGGGGGGCCCAAGTGGTGGAGGAG
CTCGCCCCCGAGGAAGGGGACTACGTGGTGACCAAGAGGAGGTACTCGGCCTTCTTCTCCACTGACTTGGACTTGTTGCT
CAGAGAGCTCGGAGTTAGTGAGGTGGTCTTGACCGGAGTGGCGACCAACGTGTGCGTGTTGCACACCGCCGCGGACGCCT
TCTTCAGGGGGTACAAGGTGACCGTGGTGGAGGACGCGACGATGTCCGTCCCCCCGGAGGAGCAACAGAGGTGGTTGGAG
TACATGAAGGCCGTGTACGGGGCGGAGGTGGTTAGCACGGCCCGAGCGATCGAGGCCCTCACTCGCCCTTGA

Upstream 100 bases:

>100_bases
GGGGGCTCTCGCGCAAACCCACAAAGGCCCGCACCGCCCGTTGGGTAAAGCCCTTGCATATAACTTGCTAAGGCTTACTG
AAGCACCACGGGGCGCCGAA

Downstream 100 bases:

>100_bases
GCTTTACGGCCTTTTCAAGGACCTTCAGCCATAGCAACATTTCTTCAGCTTCCTCCTTCCCTCCCGTATACGCCTTCGAG
GAGAGCTTGCTGAGCTTCTC

Product: isochorismatase hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKALLIIDMLNDFVNPKGKLYVPKSETIIPKVKELKRAFKEAGLPVIYTNDAHLPGVDKELELWGPHAVANTWGAQVVEE
LAPEEGDYVVTKRRYSAFFSTDLDLLLRELGVSEVVLTGVATNVCVLHTAADAFFRGYKVTVVEDATMSVPPEEQQRWLE
YMKAVYGAEVVSTARAIEALTRP

Sequences:

>Translated_183_residues
MKALLIIDMLNDFVNPKGKLYVPKSETIIPKVKELKRAFKEAGLPVIYTNDAHLPGVDKELELWGPHAVANTWGAQVVEE
LAPEEGDYVVTKRRYSAFFSTDLDLLLRELGVSEVVLTGVATNVCVLHTAADAFFRGYKVTVVEDATMSVPPEEQQRWLE
YMKAVYGAEVVSTARAIEALTRP
>Mature_183_residues
MKALLIIDMLNDFVNPKGKLYVPKSETIIPKVKELKRAFKEAGLPVIYTNDAHLPGVDKELELWGPHAVANTWGAQVVEE
LAPEEGDYVVTKRRYSAFFSTDLDLLLRELGVSEVVLTGVATNVCVLHTAADAFFRGYKVTVVEDATMSVPPEEQQRWLE
YMKAVYGAEVVSTARAIEALTRP

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

Organism=Escherichia coli, GI87081820, Length=181, Percent_Identity=34.2541436464088, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1786811, Length=173, Percent_Identity=32.9479768786127, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87081970, Length=192, Percent_Identity=30.2083333333333, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87081992, Length=167, Percent_Identity=25.748502994012, Blast_Score=64, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321401, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 20352; Mature: 20352

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLIIDMLNDFVNPKGKLYVPKSETIIPKVKELKRAFKEAGLPVIYTNDAHLPGVDKE
CCCEEHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
LELWGPHAVANTWGAQVVEELAPEEGDYVVTKRRYSAFFSTDLDLLLRELGVSEVVLTGV
HHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCHHHHHHHHCHHHHHHHHH
ATNVCVLHTAADAFFRGYKVTVVEDATMSVPPEEQQRWLEYMKAVYGAEVVSTARAIEAL
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRP
CCC
>Mature Secondary Structure
MKALLIIDMLNDFVNPKGKLYVPKSETIIPKVKELKRAFKEAGLPVIYTNDAHLPGVDKE
CCCEEHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
LELWGPHAVANTWGAQVVEELAPEEGDYVVTKRRYSAFFSTDLDLLLRELGVSEVVLTGV
HHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCHHHHHHHHCHHHHHHHHH
ATNVCVLHTAADAFFRGYKVTVVEDATMSVPPEEQQRWLEYMKAVYGAEVVSTARAIEAL
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]