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The map label for this gene is menC [H]

Identifier: 156937977

GI number: 156937977

Start: 1060958

End: 1062091

Strand: Reverse

Name: menC [H]

Synonym: Igni_1189

Alternate gene names: 156937977

Gene position: 1062091-1060958 (Counterclockwise)

Preceding gene: 156937978

Following gene: 156937976

Centisome position: 81.85

GC content: 58.99

Gene sequence:

>1134_bases
GTGGACTTGCTCTCGTGGCCCGTGCCGGAAGGGATTACGTTCAGAGTGAAGGTAATAAAAATGAAGATGAAAATAGATTT
CGAGACGAGCTTTGGAAAGGCGGAGGGGACGAGGGTAATAACTGTGGCCGAGGCCGGGGGGTGCAAGGGCTTCGGCGAGG
CCCCGGCGGAGGCGGAGCCGCTCTACAGCGGGGAGTTCGTGGACTCCGTGGTCGCATTCGCTAAGTTGGTTATACCGAAA
ATCAAAATGGTTGAGGACGTGAACGGCCTCCTGAAGGTGCTCAACAGCTATAGAGGCAACAACTTCGCCAAGTCGATGAT
AGAGTACTCGGTCCTCACTTTACTCTCGTGCTTAAGGAAGGAGAGCTTGGTCAAGGCCGTGGGCGGGAGGAAGATAAAGA
TACCCGTCCAAGAGAGCATAGGCATAGTTAAGGACGAGGACGAGCTCGTCGCTTGGGCGGAGAGGGCGCTGGAGTGGGGC
GCTAGGAGGCTGAAGGTGAAGATAAAGCCGGGCTGGGACGTGGAGCCCGTAAGGGCCCTTAAGAGGGAGTTCCCCGGAGT
CCCTGTCTTGGCCGACGCCAACGGCGCTTACGACCCCTTGAAGGACGTGCACTGGGAGTACTTGAGCAAGGTCGCCTCTT
ACGCGGACGCGTTGGAGCAGCCCTTCCCCCCTCACGAGGTCGCCTTCTCGGCGAAGTTGGCCTCCTCCGAGGGAATAGAG
GTCATTCTGGACGAGAGCTTGGAGGAGCCGGAGAGGGTGGCGGAGCTGGCTTACTTGAGCGAGGGCGTGGGCGCCCCCTT
AGGGGTCAACCTCAAGCCCCCTCGGTTCGGGGGCTTGGTTAAGAGCGTGGAAACCGTGGAGCTCATAATCGAAAACGAGT
TGCCCTTCTTCATAGGCGGTATGCTGGAAACGGCCGTCGGGAGGAGCTTGAACATGACCGTGGCGTCGCTGGCCAGGGGG
AACTTGGAGCCCTCCGACTTCAGCCCGGAGGACCACTTGTTCGAGAGGGGGCTGGCGAAGGACCCGTTCGAAGTCAAGTG
TGGGTTCGTGGAGGTGAGGGACTCCCCGGGCCTGTTGTTCGAAATTGACGAGGACTACTTGGACTCCGTAACCGTTTCTG
AGGTGGTACTTTGA

Upstream 100 bases:

>100_bases
GGAGGCCAACCCGGACTACAAGCTCTACTTAAGGCCGCACATAACCTTCTACAAGGTCCCCTACGGCCACTCTTACGTGT
TGTTCGCGAGGTGAGCCGAG

Downstream 100 bases:

>100_bases
AGCCCTTGAGGCTCCCGCCCAAGATAAAGGTGTTGGAAGCCTTGGGCGCGCTGGCCGACGGGAGGGTGAGGCTGGGGGAC
GGGAGGGCGGAGGTTGTCTC

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MDLLSWPVPEGITFRVKVIKMKMKIDFETSFGKAEGTRVITVAEAGGCKGFGEAPAEAEPLYSGEFVDSVVAFAKLVIPK
IKMVEDVNGLLKVLNSYRGNNFAKSMIEYSVLTLLSCLRKESLVKAVGGRKIKIPVQESIGIVKDEDELVAWAERALEWG
ARRLKVKIKPGWDVEPVRALKREFPGVPVLADANGAYDPLKDVHWEYLSKVASYADALEQPFPPHEVAFSAKLASSEGIE
VILDESLEEPERVAELAYLSEGVGAPLGVNLKPPRFGGLVKSVETVELIIENELPFFIGGMLETAVGRSLNMTVASLARG
NLEPSDFSPEDHLFERGLAKDPFEVKCGFVEVRDSPGLLFEIDEDYLDSVTVSEVVL

Sequences:

>Translated_377_residues
MDLLSWPVPEGITFRVKVIKMKMKIDFETSFGKAEGTRVITVAEAGGCKGFGEAPAEAEPLYSGEFVDSVVAFAKLVIPK
IKMVEDVNGLLKVLNSYRGNNFAKSMIEYSVLTLLSCLRKESLVKAVGGRKIKIPVQESIGIVKDEDELVAWAERALEWG
ARRLKVKIKPGWDVEPVRALKREFPGVPVLADANGAYDPLKDVHWEYLSKVASYADALEQPFPPHEVAFSAKLASSEGIE
VILDESLEEPERVAELAYLSEGVGAPLGVNLKPPRFGGLVKSVETVELIIENELPFFIGGMLETAVGRSLNMTVASLARG
NLEPSDFSPEDHLFERGLAKDPFEVKCGFVEVRDSPGLLFEIDEDYLDSVTVSEVVL
>Mature_377_residues
MDLLSWPVPEGITFRVKVIKMKMKIDFETSFGKAEGTRVITVAEAGGCKGFGEAPAEAEPLYSGEFVDSVVAFAKLVIPK
IKMVEDVNGLLKVLNSYRGNNFAKSMIEYSVLTLLSCLRKESLVKAVGGRKIKIPVQESIGIVKDEDELVAWAERALEWG
ARRLKVKIKPGWDVEPVRALKREFPGVPVLADANGAYDPLKDVHWEYLSKVASYADALEQPFPPHEVAFSAKLASSEGIE
VILDESLEEPERVAELAYLSEGVGAPLGVNLKPPRFGGLVKSVETVELIIENELPFFIGGMLETAVGRSLNMTVASLARG
NLEPSDFSPEDHLFERGLAKDPFEVKCGFVEVRDSPGLLFEIDEDYLDSVTVSEVVL

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 41358; Mature: 41358

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLSWPVPEGITFRVKVIKMKMKIDFETSFGKAEGTRVITVAEAGGCKGFGEAPAEAEP
CCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
LYSGEFVDSVVAFAKLVIPKIKMVEDVNGLLKVLNSYRGNNFAKSMIEYSVLTLLSCLRK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ESLVKAVGGRKIKIPVQESIGIVKDEDELVAWAERALEWGARRLKVKIKPGWDVEPVRAL
HHHHHHHCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
KREFPGVPVLADANGAYDPLKDVHWEYLSKVASYADALEQPFPPHEVAFSAKLASSEGIE
HHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEHHHCCCCCCE
VILDESLEEPERVAELAYLSEGVGAPLGVNLKPPRFGGLVKSVETVELIIENELPFFIGG
EEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCHHHHH
MLETAVGRSLNMTVASLARGNLEPSDFSPEDHLFERGLAKDPFEVKCGFVEVRDSPGLLF
HHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEEEECCCCEEE
EIDEDYLDSVTVSEVVL
EECHHHHCCCHHHHHCC
>Mature Secondary Structure
MDLLSWPVPEGITFRVKVIKMKMKIDFETSFGKAEGTRVITVAEAGGCKGFGEAPAEAEP
CCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
LYSGEFVDSVVAFAKLVIPKIKMVEDVNGLLKVLNSYRGNNFAKSMIEYSVLTLLSCLRK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ESLVKAVGGRKIKIPVQESIGIVKDEDELVAWAERALEWGARRLKVKIKPGWDVEPVRAL
HHHHHHHCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHH
KREFPGVPVLADANGAYDPLKDVHWEYLSKVASYADALEQPFPPHEVAFSAKLASSEGIE
HHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEHHHCCCCCCE
VILDESLEEPERVAELAYLSEGVGAPLGVNLKPPRFGGLVKSVETVELIIENELPFFIGG
EEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCHHHHH
MLETAVGRSLNMTVASLARGNLEPSDFSPEDHLFERGLAKDPFEVKCGFVEVRDSPGLLF
HHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEEEEECCCCEEE
EIDEDYLDSVTVSEVVL
EECHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]