Click here to switch to the map view.

The map label for this gene is atsB [H]

Identifier: 156937895

GI number: 156937895

Start: 987188

End: 988180

Strand: Reverse

Name: atsB [H]

Synonym: Igni_1107

Alternate gene names: 156937895

Gene position: 988180-987188 (Counterclockwise)

Preceding gene: 156937897

Following gene: 156937893

Centisome position: 76.16

GC content: 60.42

Gene sequence:

>993_bases
ATGAAGCTGAGGAGCATAATATGGATCTTGACCGGGAAGTGCAACTTGGACTGCAAGCACTGCTACGCCAAGAGGTTCCT
AGACCCCTCCAAGTGGGGGCCGGAAGTGGGGAGGGAGGAGGTCGAGAGGGTAATGAGGGAGGCGTTGGACTTGGGGCTGG
AGTGGACTAACTTCAGCGGAGGGGAGCTGCTCTTCTTCAAGCCTTGGGTCCTCGAAGTCCTAGCGGACTTGTCCCAGAGG
GGGGCGGACGTCAGCTTAGTGACCAACGGGATGTTCGTAACCAAGGAGAGGGCCCGGTACATGGCCGAGAACGGGATCTT
CGCTTACGTCTCCTTGGACGGCGACAAGGAGTCCCACGAGTTCTTGAGGGGCAAGGGCACTTGGGAGGCCACCTTGAGGG
GGATAAACAACTTGAGGGAGGCCGGGGCCGAGTTCGCGCTCGTCATGGCGGTGGGGAAACACAACTACTCCAAGGTGGGC
GAGTTCGTGAGGACGGCGAGGGCTCTGGGGGCTTCGCACGTAGCCATAATTCCCATAATGCCCTTCGGGAACGCCCTCAA
GAACGGAGTATACGTGGGTCGCGACGAGTTCGTAGCCGCGTTGAAGTTGTTTGAGGAAGCGTTGGAAGAAAACGAGATGA
GGGGGAGCGTGTGGTGCGCGCCTTGGGCGAAGTACGTAGTTAAGAGCAAGAGGGTGAGCGCGGGGAACTGTAGGAAGGCG
TCGGGCATGGACATAGGCCCCGACGGGTGGACCATGCTCTGCGACGTGTTAGACTTCAAGATAAACGACGTCAAGGGGAG
GCCGTTGGAAGAGGTGTGGGAAGAGTACTTGAGGCACCCGTTGGTGAGGAGGGTCTCCTCGCCCCCTCCCGGAGGGTGCG
AGTGCCCCTACTACAAGAACTGCATGGGAGGGTGCTTCGCGAGGGCGCTGGCCTCCGGGGCAGGGTTCGAGGGGGACCCG
CTGTGCCCGCTCAGACGAGCTCCAGCTTCTTGA

Upstream 100 bases:

>100_bases
CAAAATCTCGGACCCGGGCTGCGCGGCGCCGGGGGAAGGTTAGAAGCGTGTTGTCCCCGCTTCATTAATCCTCCTCCGGA
CGCCGTCACAAGGAGCGGAA

Downstream 100 bases:

>100_bases
GCCTCCCGAAGTTGTACATCAGCGTGTAGCCGCAGTTCTTGCACCTCAGCTTTACCACTTGGTTCTTGGTGACCTTGGCG
AACCTCTTCTGCTCCGGCTT

Product: radical SAM domain-containing protein

Products: NA

Alternate protein names: AnSME; Arylsulfatase-activating protein; Ser-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKLRSIIWILTGKCNLDCKHCYAKRFLDPSKWGPEVGREEVERVMREALDLGLEWTNFSGGELLFFKPWVLEVLADLSQR
GADVSLVTNGMFVTKERARYMAENGIFAYVSLDGDKESHEFLRGKGTWEATLRGINNLREAGAEFALVMAVGKHNYSKVG
EFVRTARALGASHVAIIPIMPFGNALKNGVYVGRDEFVAALKLFEEALEENEMRGSVWCAPWAKYVVKSKRVSAGNCRKA
SGMDIGPDGWTMLCDVLDFKINDVKGRPLEEVWEEYLRHPLVRRVSSPPPGGCECPYYKNCMGGCFARALASGAGFEGDP
LCPLRRAPAS

Sequences:

>Translated_330_residues
MKLRSIIWILTGKCNLDCKHCYAKRFLDPSKWGPEVGREEVERVMREALDLGLEWTNFSGGELLFFKPWVLEVLADLSQR
GADVSLVTNGMFVTKERARYMAENGIFAYVSLDGDKESHEFLRGKGTWEATLRGINNLREAGAEFALVMAVGKHNYSKVG
EFVRTARALGASHVAIIPIMPFGNALKNGVYVGRDEFVAALKLFEEALEENEMRGSVWCAPWAKYVVKSKRVSAGNCRKA
SGMDIGPDGWTMLCDVLDFKINDVKGRPLEEVWEEYLRHPLVRRVSSPPPGGCECPYYKNCMGGCFARALASGAGFEGDP
LCPLRRAPAS
>Mature_330_residues
MKLRSIIWILTGKCNLDCKHCYAKRFLDPSKWGPEVGREEVERVMREALDLGLEWTNFSGGELLFFKPWVLEVLADLSQR
GADVSLVTNGMFVTKERARYMAENGIFAYVSLDGDKESHEFLRGKGTWEATLRGINNLREAGAEFALVMAVGKHNYSKVG
EFVRTARALGASHVAIIPIMPFGNALKNGVYVGRDEFVAALKLFEEALEENEMRGSVWCAPWAKYVVKSKRVSAGNCRKA
SGMDIGPDGWTMLCDVLDFKINDVKGRPLEEVWEEYLRHPLVRRVSSPPPGGCECPYYKNCMGGCFARALASGAGFEGDP
LCPLRRAPAS

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of serine ('Ser-72' in the arylsulfatase AtsA) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemica

COG id: COG0535

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 36728; Mature: 36728

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRSIIWILTGKCNLDCKHCYAKRFLDPSKWGPEVGREEVERVMREALDLGLEWTNFSG
CCHHEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHCCCEEECCCC
GELLFFKPWVLEVLADLSQRGADVSLVTNGMFVTKERARYMAENGIFAYVSLDGDKESHE
CEEEEECHHHHHHHHHHHHCCCCEEEEECCEEEEHHHHHHHHCCCEEEEEEECCCCHHHH
FLRGKGTWEATLRGINNLREAGAEFALVMAVGKHNYSKVGEFVRTARALGASHVAIIPIM
HHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEC
PFGNALKNGVYVGRDEFVAALKLFEEALEENEMRGSVWCAPWAKYVVKSKRVSAGNCRKA
CCCHHHHCCEEECHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCCC
SGMDIGPDGWTMLCDVLDFKINDVKGRPLEEVWEEYLRHPLVRRVSSPPPGGCECPYYKN
CCCCCCCCHHHHHHHHHHCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
CMGGCFARALASGAGFEGDPLCPLRRAPAS
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLRSIIWILTGKCNLDCKHCYAKRFLDPSKWGPEVGREEVERVMREALDLGLEWTNFSG
CCHHEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHCCCEEECCCC
GELLFFKPWVLEVLADLSQRGADVSLVTNGMFVTKERARYMAENGIFAYVSLDGDKESHE
CEEEEECHHHHHHHHHHHHCCCCEEEEECCEEEEHHHHHHHHCCCEEEEEEECCCCHHHH
FLRGKGTWEATLRGINNLREAGAEFALVMAVGKHNYSKVGEFVRTARALGASHVAIIPIM
HHCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEC
PFGNALKNGVYVGRDEFVAALKLFEEALEENEMRGSVWCAPWAKYVVKSKRVSAGNCRKA
CCCHHHHCCEEECHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCCC
SGMDIGPDGWTMLCDVLDFKINDVKGRPLEEVWEEYLRHPLVRRVSSPPPGGCECPYYKN
CCCCCCCCHHHHHHHHHHCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
CMGGCFARALASGAGFEGDPLCPLRRAPAS
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180918 [H]