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The map label for this gene is ileS [H]

Identifier: 156937807

GI number: 156937807

Start: 905292

End: 908369

Strand: Reverse

Name: ileS [H]

Synonym: Igni_1017

Alternate gene names: 156937807

Gene position: 908369-905292 (Counterclockwise)

Preceding gene: 156937809

Following gene: 156937806

Centisome position: 70.01

GC content: 57.96

Gene sequence:

>3078_bases
GTGGAGCCGAAGTACGACCCCCTCAAAGTGGAGGAGGAAGTGTTCAAGTTCTGGAAAGAGAATAAGATATACGAGAAAGT
TAAAGAGCTTAGCAAAAAGAGGGGGAAGGTTAAGCTCTTCCGGTTCTTGGAGGGGCCGCCCACGGCCAACGGGTTCATGC
ACGTAGGCCACATGAGGGGGAGGACCTACAAGGACGTGATCCTAAGGTTCTGGAGGATGAAGGGGTACTGGGTGTGGGAC
CAAGCCGGGTGGGACACCCAAGGCCTCCCCGTCGAGCTGGAGGTGGAGAAGAAGCACGGCTTCAAGAGCAAGAAAGACAT
ACTCAAGTACGGGGTAGAGAAGTTCGTCAAGGAGTGTCAAGAGCTGGTGGACTACTACATCTCCCACTGGAGGGCCGACA
GCGAGAGGATGGGCCTCTGGCTGGACTACGACAACGCCTACGAGACCCGCCACCCCAAGTACTTGGACGCCGCCTGGAGC
TACTTGAAGAAGATGTTCGATCAAGGGAGGATATACAAGGGCTTGAGGGTAGTCGCCGTCTGCCCGCGCTGCGAGACCGC
GCTCTCCTCCCACGAGGTCGCCTTGGGCTACAAGACGGTTAAGGACCCGAGCTTCTACTTCAAGCTCCCCTTGAAAGACG
AGGAAGAGACCTACCTCGTCGCTTGGACCACCACCCCTTGGACCATAATCGCCAACGAGGCCGCCGCGGTTCACCCTTAC
GAGACCTACGTGAAAATAGAGGTGGACGCTAACGGGAAGAAGGAGAAGTGGATACTGGCTGAGAAGAGGCTAGAGCCCTT
CGCGAAGGAAGTAGGTTTGAAGGACTACAAGGTCCTCGAGAAGTTCAAGGGGGAGGAGCTGATAGGGAAGGAGTACGTCC
ACCCGTTGTTAGAGGAGGTCCCCGCCCACAAGGAGCACCCTAAGCCCCACCACACCGTGATCGAGGGCGCGGTCGTCAGG
AAGAAAGTACTGGTAAACGGGAAAGAAATAGAGGAGAAGCAGATATTCGTATCGATGGACTCCGGTACCGGAATAGTCCA
CATGGCCCCCGCCCACGGCGCGGAGGACTTCGAGGCTTGTAGGCGGGTCGGCATAGAGGTGTTCAGGCCGATAAGGAAGG
ACGGCCACTTCACCGAGGAGGCCGGCAAGTACGCGGGCATGTGGTTTAAGGAGGCGGAGAAGGAAGTTATAAAGGACCTA
AAGGAGAAGGGCCTTGCCGTCCACGTAGGCACGATCGAGCACGAGTACCCCCACTGCTGGAGGTGCGACACGCCGCTGAT
GTACTACGCCGACGAACAGTGGTTCATAAAGGTCGAGGACTTAAGGGAGACGTTAGTCAACGAGAACGACAAGGTTACTT
GGTACCCCAAGTGGGCCTACGACAGGATGAGCGACTGGCTCCAGAACGCGAAGGACTGGACTATAAGCCGAGAGAGGTTC
TGGGGGACCCCTCTGCCCATATGGACTTGTACTTCGTGCGGCCACCGCGTGGCGGTCTCCAGCCTAGATGAGCTCAAGAA
AGTAGCCCTTAACCCGGAGGCCGTGGTGGACCACCACAGGCCTTGGGTCGACGAGGTGAAGCTCAAGTGCCCCAAGTGCG
GGGGCGTGATGGTAAGGGAGCCCTACGTCGTGGACGTGTGGCTAGACTCCGGCGTAGCCCACACCGCCTCCCTCAAGCAG
ATAGGCGCGGAGGACTACTGGGACTTGTTCTACCCGTACGACTGGATAACTGAGGCCCTCGACCAGACCAGAGGCTGGTT
CTACACCTTGTTGGTTACCGGCGTCACGTGGCACGGGAGGGCCCCCTACAAGCAAGTGCTCACCCAAGGCCACATACTGG
ACAAGCACGGGAAGAAGATGAGCAAGAGCAAGGGTAACGTGGTCTGGGCTAAGGACGTGTTCAAGACTTACGGGGCGGAC
CCGGTGAGGTTCTTCTTCGCGATAAAGAGCGCCCCTTGGGACTCGGTACGCTTCGACCCGGAGGACATAAAGCTCGCTAA
GAGGACCTTGGACATACTCTGGAACTCCGTCAAGTTCGCGAAGAGCTACATGGAGCTCGACAAGTGGAGCTTGGAGAAGT
TGGAGGAGGGCTTGAAGAGCTTGGAGCCGGAGGACAGCTGGGTCCTCTGGAAGCTAAACGAGTACTCCAAGAGAGTCGCC
GAGGAGTTGGAGAGGTCCGCCATTCACCGCGCCGCACAAGCCCTCCAAGAGTTCATAGTTGAGGTGTTGAGCCACAAGTA
CATAACGCTCGTGAGGCCTAGGGTGTGGGAGGAAGAGGAGACCCCCTCCAAGCTGGCCGCCTACAGCGCCCTGTTCCTCG
CCTTGGACGCCGCAATAAGGATGAGCGCTCCCTTCGTCCCGTTCTTGGCGGAGTACTTGTACCAGCGCTTCCAGAGGGCC
TTGGGCTTCGAGGAGGAGAGCGTCCACATGCTCCAGTGGCCGGAGGAGAACAGCTTGTACGACCCGGAGGAGGCCAAGGC
TGTGGAGGAGCTCTTGGAGGCGGCGGAGAAGGTGTTGGCCCTTAGGACGGAGAGGGGAGTCAAGAGGAGGTGGCCCCTCC
CGGAGGCCTACGTGGTGGTGAAGAGCAGGGAAGAAAAGGCGGAGAGGGTGAAGGTGAAGAGGGGCAACAAGGAGGCCGAA
GAAGTGATATACAAACCCGCCTTGAGCGTCGTGGCCGTTAAGAGGGCTGCCAAGGCGCTCGGCGTGTACGCGAACGTGTT
GGACGTCAAGGTTGTGGAGGAGCCTCCGGCCGGCGACTTCGACGTGATAGAGACGGAGAGCTTGAAGGTTTACGTCAAGG
TGAGGCTGGACGAGAGGACCAAGATGCTGGGCTTGGCAAGAGAGGTGATAAGGAGGATACAAACAATGAGGAAGGAAGAG
GACTTACCGTTGGACTACGTCCTGAAGAAGGTAATAGTTTTCAGCGACAACGAGGAGATACTGAAGGCCGTGGAAGAGTT
CAAGGAGTACGTGGCCAAGGAGGTGAGGGCAGAAGAGGTGGTGACCTCCGGCGAGCCCCCGGAGGGCAAAGAATGGAGCT
TAGAAGGCTCTAAGGTGGTCATAGCTCTGGTGAAGTGA

Upstream 100 bases:

>100_bases
CCCAACAGAAGCAGGGGTCCTTGTTACACACCAAGTCGCACAAGCGACGCCCCGGAGAGAATTTTTCCGACCCCCCTTTG
CCCGTTAAGGGTACCACGCA

Downstream 100 bases:

>100_bases
GCGTGTGTTGGAGCGCCCTCTTGCTCTTAGCGGTCCTAACCTTCGGAGAGGCCTTGTACTTCTTTTTCTCGGTGGTCACC
GGGAACTGGGGCGGCGCGGC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1025; Mature: 1025

Protein sequence:

>1025_residues
MEPKYDPLKVEEEVFKFWKENKIYEKVKELSKKRGKVKLFRFLEGPPTANGFMHVGHMRGRTYKDVILRFWRMKGYWVWD
QAGWDTQGLPVELEVEKKHGFKSKKDILKYGVEKFVKECQELVDYYISHWRADSERMGLWLDYDNAYETRHPKYLDAAWS
YLKKMFDQGRIYKGLRVVAVCPRCETALSSHEVALGYKTVKDPSFYFKLPLKDEEETYLVAWTTTPWTIIANEAAAVHPY
ETYVKIEVDANGKKEKWILAEKRLEPFAKEVGLKDYKVLEKFKGEELIGKEYVHPLLEEVPAHKEHPKPHHTVIEGAVVR
KKVLVNGKEIEEKQIFVSMDSGTGIVHMAPAHGAEDFEACRRVGIEVFRPIRKDGHFTEEAGKYAGMWFKEAEKEVIKDL
KEKGLAVHVGTIEHEYPHCWRCDTPLMYYADEQWFIKVEDLRETLVNENDKVTWYPKWAYDRMSDWLQNAKDWTISRERF
WGTPLPIWTCTSCGHRVAVSSLDELKKVALNPEAVVDHHRPWVDEVKLKCPKCGGVMVREPYVVDVWLDSGVAHTASLKQ
IGAEDYWDLFYPYDWITEALDQTRGWFYTLLVTGVTWHGRAPYKQVLTQGHILDKHGKKMSKSKGNVVWAKDVFKTYGAD
PVRFFFAIKSAPWDSVRFDPEDIKLAKRTLDILWNSVKFAKSYMELDKWSLEKLEEGLKSLEPEDSWVLWKLNEYSKRVA
EELERSAIHRAAQALQEFIVEVLSHKYITLVRPRVWEEEETPSKLAAYSALFLALDAAIRMSAPFVPFLAEYLYQRFQRA
LGFEEESVHMLQWPEENSLYDPEEAKAVEELLEAAEKVLALRTERGVKRRWPLPEAYVVVKSREEKAERVKVKRGNKEAE
EVIYKPALSVVAVKRAAKALGVYANVLDVKVVEEPPAGDFDVIETESLKVYVKVRLDERTKMLGLAREVIRRIQTMRKEE
DLPLDYVLKKVIVFSDNEEILKAVEEFKEYVAKEVRAEEVVTSGEPPEGKEWSLEGSKVVIALVK

Sequences:

>Translated_1025_residues
MEPKYDPLKVEEEVFKFWKENKIYEKVKELSKKRGKVKLFRFLEGPPTANGFMHVGHMRGRTYKDVILRFWRMKGYWVWD
QAGWDTQGLPVELEVEKKHGFKSKKDILKYGVEKFVKECQELVDYYISHWRADSERMGLWLDYDNAYETRHPKYLDAAWS
YLKKMFDQGRIYKGLRVVAVCPRCETALSSHEVALGYKTVKDPSFYFKLPLKDEEETYLVAWTTTPWTIIANEAAAVHPY
ETYVKIEVDANGKKEKWILAEKRLEPFAKEVGLKDYKVLEKFKGEELIGKEYVHPLLEEVPAHKEHPKPHHTVIEGAVVR
KKVLVNGKEIEEKQIFVSMDSGTGIVHMAPAHGAEDFEACRRVGIEVFRPIRKDGHFTEEAGKYAGMWFKEAEKEVIKDL
KEKGLAVHVGTIEHEYPHCWRCDTPLMYYADEQWFIKVEDLRETLVNENDKVTWYPKWAYDRMSDWLQNAKDWTISRERF
WGTPLPIWTCTSCGHRVAVSSLDELKKVALNPEAVVDHHRPWVDEVKLKCPKCGGVMVREPYVVDVWLDSGVAHTASLKQ
IGAEDYWDLFYPYDWITEALDQTRGWFYTLLVTGVTWHGRAPYKQVLTQGHILDKHGKKMSKSKGNVVWAKDVFKTYGAD
PVRFFFAIKSAPWDSVRFDPEDIKLAKRTLDILWNSVKFAKSYMELDKWSLEKLEEGLKSLEPEDSWVLWKLNEYSKRVA
EELERSAIHRAAQALQEFIVEVLSHKYITLVRPRVWEEEETPSKLAAYSALFLALDAAIRMSAPFVPFLAEYLYQRFQRA
LGFEEESVHMLQWPEENSLYDPEEAKAVEELLEAAEKVLALRTERGVKRRWPLPEAYVVVKSREEKAERVKVKRGNKEAE
EVIYKPALSVVAVKRAAKALGVYANVLDVKVVEEPPAGDFDVIETESLKVYVKVRLDERTKMLGLAREVIRRIQTMRKEE
DLPLDYVLKKVIVFSDNEEILKAVEEFKEYVAKEVRAEEVVTSGEPPEGKEWSLEGSKVVIALVK
>Mature_1025_residues
MEPKYDPLKVEEEVFKFWKENKIYEKVKELSKKRGKVKLFRFLEGPPTANGFMHVGHMRGRTYKDVILRFWRMKGYWVWD
QAGWDTQGLPVELEVEKKHGFKSKKDILKYGVEKFVKECQELVDYYISHWRADSERMGLWLDYDNAYETRHPKYLDAAWS
YLKKMFDQGRIYKGLRVVAVCPRCETALSSHEVALGYKTVKDPSFYFKLPLKDEEETYLVAWTTTPWTIIANEAAAVHPY
ETYVKIEVDANGKKEKWILAEKRLEPFAKEVGLKDYKVLEKFKGEELIGKEYVHPLLEEVPAHKEHPKPHHTVIEGAVVR
KKVLVNGKEIEEKQIFVSMDSGTGIVHMAPAHGAEDFEACRRVGIEVFRPIRKDGHFTEEAGKYAGMWFKEAEKEVIKDL
KEKGLAVHVGTIEHEYPHCWRCDTPLMYYADEQWFIKVEDLRETLVNENDKVTWYPKWAYDRMSDWLQNAKDWTISRERF
WGTPLPIWTCTSCGHRVAVSSLDELKKVALNPEAVVDHHRPWVDEVKLKCPKCGGVMVREPYVVDVWLDSGVAHTASLKQ
IGAEDYWDLFYPYDWITEALDQTRGWFYTLLVTGVTWHGRAPYKQVLTQGHILDKHGKKMSKSKGNVVWAKDVFKTYGAD
PVRFFFAIKSAPWDSVRFDPEDIKLAKRTLDILWNSVKFAKSYMELDKWSLEKLEEGLKSLEPEDSWVLWKLNEYSKRVA
EELERSAIHRAAQALQEFIVEVLSHKYITLVRPRVWEEEETPSKLAAYSALFLALDAAIRMSAPFVPFLAEYLYQRFQRA
LGFEEESVHMLQWPEENSLYDPEEAKAVEELLEAAEKVLALRTERGVKRRWPLPEAYVVVKSREEKAERVKVKRGNKEAE
EVIYKPALSVVAVKRAAKALGVYANVLDVKVVEEPPAGDFDVIETESLKVYVKVRLDERTKMLGLAREVIRRIQTMRKEE
DLPLDYVLKKVIVFSDNEEILKAVEEFKEYVAKEVRAEEVVTSGEPPEGKEWSLEGSKVVIALVK

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1067, Percent_Identity=31.302717900656, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI94721241, Length=1067, Percent_Identity=31.302717900656, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI46852147, Length=831, Percent_Identity=26.7148014440433, Blast_Score=261, Evalue=3e-69,
Organism=Homo sapiens, GI5454158, Length=936, Percent_Identity=22.9700854700855, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI268370293, Length=921, Percent_Identity=21.8241042345277, Blast_Score=167, Evalue=7e-41,
Organism=Homo sapiens, GI268370297, Length=921, Percent_Identity=21.8241042345277, Blast_Score=167, Evalue=7e-41,
Organism=Homo sapiens, GI268370295, Length=876, Percent_Identity=22.1461187214612, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI7661872, Length=186, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=8e-11,
Organism=Escherichia coli, GI2367096, Length=812, Percent_Identity=28.9408866995074, Blast_Score=321, Evalue=2e-88,
Organism=Escherichia coli, GI1790708, Length=953, Percent_Identity=22.0356768100735, Blast_Score=186, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17541896, Length=870, Percent_Identity=32.2988505747126, Blast_Score=465, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI71980946, Length=810, Percent_Identity=25.8024691358025, Blast_Score=225, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17510661, Length=906, Percent_Identity=22.9580573951435, Blast_Score=208, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI72001587, Length=821, Percent_Identity=23.142509135201, Blast_Score=149, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1061, Percent_Identity=30.8199811498586, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6325217, Length=851, Percent_Identity=23.8542890716804, Blast_Score=218, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6321531, Length=942, Percent_Identity=24.416135881104, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI28574730, Length=1062, Percent_Identity=30.6967984934087, Blast_Score=468, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24668547, Length=1062, Percent_Identity=30.6967984934087, Blast_Score=468, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24668543, Length=1062, Percent_Identity=30.6967984934087, Blast_Score=468, Evalue=1e-131,
Organism=Drosophila melanogaster, GI281366294, Length=886, Percent_Identity=26.2979683972912, Blast_Score=253, Evalue=5e-67,
Organism=Drosophila melanogaster, GI17864482, Length=925, Percent_Identity=21.9459459459459, Blast_Score=176, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24653289, Length=925, Percent_Identity=21.9459459459459, Blast_Score=176, Evalue=8e-44,
Organism=Drosophila melanogaster, GI21355675, Length=507, Percent_Identity=24.2603550295858, Blast_Score=137, Evalue=4e-32,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 119290; Mature: 119290

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPKYDPLKVEEEVFKFWKENKIYEKVKELSKKRGKVKLFRFLEGPPTANGFMHVGHMRG
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCC
RTYKDVILRFWRMKGYWVWDQAGWDTQGLPVELEVEKKHGFKSKKDILKYGVEKFVKECQ
CHHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHH
ELVDYYISHWRADSERMGLWLDYDNAYETRHPKYLDAAWSYLKKMFDQGRIYKGLRVVAV
HHHHHHHHHHCCCCHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCEEEEE
CPRCETALSSHEVALGYKTVKDPSFYFKLPLKDEEETYLVAWTTTPWTIIANEAAAVHPY
CCCHHHHHCCCCEEECEEEECCCCEEEEECCCCCCCEEEEEEECCCEEEEECCCCEECCE
ETYVKIEVDANGKKEKWILAEKRLEPFAKEVGLKDYKVLEKFKGEELIGKEYVHPLLEEV
EEEEEEEECCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
PAHKEHPKPHHTVIEGAVVRKKVLVNGKEIEEKQIFVSMDSGTGIVHMAPAHGAEDFEAC
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHH
RRVGIEVFRPIRKDGHFTEEAGKYAGMWFKEAEKEVIKDLKEKGLAVHVGTIEHEYPHCW
HHHCHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCE
RCDTPLMYYADEQWFIKVEDLRETLVNENDKVTWYPKWAYDRMSDWLQNAKDWTISRERF
ECCCCEEEEECCCEEEEHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCCCCEEHHHC
WGTPLPIWTCTSCGHRVAVSSLDELKKVALNPEAVVDHHRPWVDEVKLKCPKCGGVMVRE
CCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHCCCCCCCCEEEEC
PYVVDVWLDSGVAHTASLKQIGAEDYWDLFYPYDWITEALDQTRGWFYTLLVTGVTWHGR
CEEEEEEECCCCHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCEEEEEHHCCCCCCC
APYKQVLTQGHILDKHGKKMSKSKGNVVWAKDVFKTYGADPVRFFFAIKSAPWDSVRFDP
CCHHHHHHCCCEECCCCCHHHCCCCCEEEHHHHHHHHCCCCEEEEEEEECCCCCCCCCCH
EDIKLAKRTLDILWNSVKFAKSYMELDKWSLEKLEEGLKSLEPEDSWVLWKLNEYSKRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHH
EELERSAIHRAAQALQEFIVEVLSHKYITLVRPRVWEEEETPSKLAAYSALFLALDAAIR
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
MSAPFVPFLAEYLYQRFQRALGFEEESVHMLQWPEENSLYDPEEAKAVEELLEAAEKVLA
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
LRTERGVKRRWPLPEAYVVVKSREEKAERVKVKRGNKEAEEVIYKPALSVVAVKRAAKAL
HHHHCCCHHCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GVYANVLDVKVVEEPPAGDFDVIETESLKVYVKVRLDERTKMLGLAREVIRRIQTMRKEE
HHHHHHEEEEEECCCCCCCCCEEECCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
DLPLDYVLKKVIVFSDNEEILKAVEEFKEYVAKEVRAEEVVTSGEPPEGKEWSLEGSKVV
CCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEE
IALVK
EEEEC
>Mature Secondary Structure
MEPKYDPLKVEEEVFKFWKENKIYEKVKELSKKRGKVKLFRFLEGPPTANGFMHVGHMRG
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCC
RTYKDVILRFWRMKGYWVWDQAGWDTQGLPVELEVEKKHGFKSKKDILKYGVEKFVKECQ
CHHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHH
ELVDYYISHWRADSERMGLWLDYDNAYETRHPKYLDAAWSYLKKMFDQGRIYKGLRVVAV
HHHHHHHHHHCCCCHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCEEEEE
CPRCETALSSHEVALGYKTVKDPSFYFKLPLKDEEETYLVAWTTTPWTIIANEAAAVHPY
CCCHHHHHCCCCEEECEEEECCCCEEEEECCCCCCCEEEEEEECCCEEEEECCCCEECCE
ETYVKIEVDANGKKEKWILAEKRLEPFAKEVGLKDYKVLEKFKGEELIGKEYVHPLLEEV
EEEEEEEECCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
PAHKEHPKPHHTVIEGAVVRKKVLVNGKEIEEKQIFVSMDSGTGIVHMAPAHGAEDFEAC
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHH
RRVGIEVFRPIRKDGHFTEEAGKYAGMWFKEAEKEVIKDLKEKGLAVHVGTIEHEYPHCW
HHHCHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCE
RCDTPLMYYADEQWFIKVEDLRETLVNENDKVTWYPKWAYDRMSDWLQNAKDWTISRERF
ECCCCEEEEECCCEEEEHHHHHHHHCCCCCCEEEEECHHHHHHHHHHCCCCCCCEEHHHC
WGTPLPIWTCTSCGHRVAVSSLDELKKVALNPEAVVDHHRPWVDEVKLKCPKCGGVMVRE
CCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHCCCCCCCCEEEEC
PYVVDVWLDSGVAHTASLKQIGAEDYWDLFYPYDWITEALDQTRGWFYTLLVTGVTWHGR
CEEEEEEECCCCHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCEEEEEHHCCCCCCC
APYKQVLTQGHILDKHGKKMSKSKGNVVWAKDVFKTYGADPVRFFFAIKSAPWDSVRFDP
CCHHHHHHCCCEECCCCCHHHCCCCCEEEHHHHHHHHCCCCEEEEEEEECCCCCCCCCCH
EDIKLAKRTLDILWNSVKFAKSYMELDKWSLEKLEEGLKSLEPEDSWVLWKLNEYSKRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHH
EELERSAIHRAAQALQEFIVEVLSHKYITLVRPRVWEEEETPSKLAAYSALFLALDAAIR
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
MSAPFVPFLAEYLYQRFQRALGFEEESVHMLQWPEENSLYDPEEAKAVEELLEAAEKVLA
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
LRTERGVKRRWPLPEAYVVVKSREEKAERVKVKRGNKEAEEVIYKPALSVVAVKRAAKAL
HHHHCCCHHCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GVYANVLDVKVVEEPPAGDFDVIETESLKVYVKVRLDERTKMLGLAREVIRRIQTMRKEE
HHHHHHEEEEEECCCCCCCCCEEECCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
DLPLDYVLKKVIVFSDNEEILKAVEEFKEYVAKEVRAEEVVTSGEPPEGKEWSLEGSKVV
CCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEE
IALVK
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]