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The map label for this gene is 156937788

Identifier: 156937788

GI number: 156937788

Start: 888494

End: 889426

Strand: Reverse

Name: 156937788

Synonym: Igni_0998

Alternate gene names: NA

Gene position: 889426-888494 (Counterclockwise)

Preceding gene: 156937789

Following gene: 156937787

Centisome position: 68.55

GC content: 58.52

Gene sequence:

>933_bases
TTGAGGTACGTCCTAGATGAGGAAAAGGTAAAGGCTTTTATAAAGGAGGTCAAGCCCTCCAAGGTCCTAGTCGAGGCCCC
TCCCGGCCTCTTCAAGCCCGCGAAGAGAGTTTGTGAGCTGGTGAGCGTCGAGTGCGAGATATCTGCAATGCCCGTCTTCG
GCGGCTGCCTCGCGTACGAGTTCCTCGAGGGCGACGCTATAATACACTTAGGCCACAACCCCTACCCTTGGTGGACCCCA
AAGAAGCCCACCTTGTACTTGGAGGTGCCTGTCGAAGTCGAGACCGACGTAGAAGTCGTCAAAGACAAACTGAAGGGTAA
GAGAGTGGTATTGGGAGCCGTCGTCCAACACTTGAACTTGTTGGACGAGCTAAAGGAGCGCCTAAGGGGGTGGGGGTTCG
AGCCCCTCACCTTCACGTCCAAGGGACTTAAGGAGGGGCAAGTGCTCGGCTGCGACTACAGGAACTTGAGGAGGGGGTAC
GACGATTACCTAATAGTCGCCGGCGGGAGGTTCCACGCCTTGGGCGCGGCGCTGTACTTGAAGCGCGACGTGCTGGCCTT
CGACCCCTACTCGTCGCGGGTCGAGAGGTTGGACCCGACTAAGGCCTTGGCGAGGAGAATGTGGCTGGTGAAGGAGGCTT
CGAACACCAAAACTGTCGCGCTAGTGGACGGCCACGAGGGCCAAGCGAGGCCCGGGCTCGTAAGGGCGCTGAAAGAGATG
GCGGAGAAGGCGGGAATGAGGGTAAGGGTGTATAAGTCCCTAATCCTTACGAGGGAGTTCGTACTGAACTTGCCGGAGGA
AGTGGTGGTCACACTCTCTTGTCCCCGGCTGGCCTTGGACGACTTCGGCGACGTGCGGGAGAAGGTAGTGCTCGCCCCCG
GGGAGTTCAGAGCCGCTGTACTGGGTTTGGACTCGTATGCGTTTCCCTTTTAG

Upstream 100 bases:

>100_bases
GCAGTACGTCGATAAGGTTAAGGAAGCCTTGAAGATAGCCGCTTCCAAGATGCCGATGCCTTGTAGGATAGAAGTGGTAG
AACTCAAGAAGTGAGCTCCC

Downstream 100 bases:

>100_bases
ACTAAGAGGGTCCGTCCAGATAGGGAGAAAGTTTGGGTCTGGACGACTACTATACTAAGGCCTTCGTAGCGGTAGAGGGG
AAGCTCCTCTACGCGGTGGT

Product: diphthamide biosynthesis protein

Products: NA

Alternate protein names: Diphthine Synthase DPH2 Subunit; Diphthamide Synthesis Protein; Diphthamide Synthase Subunit; Diphthamide Synthesis DPH2 Protein; Diphthamide Biosynthesis -Related Domain; Diptheria xin Resistance Protein

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRYVLDEEKVKAFIKEVKPSKVLVEAPPGLFKPAKRVCELVSVECEISAMPVFGGCLAYEFLEGDAIIHLGHNPYPWWTP
KKPTLYLEVPVEVETDVEVVKDKLKGKRVVLGAVVQHLNLLDELKERLRGWGFEPLTFTSKGLKEGQVLGCDYRNLRRGY
DDYLIVAGGRFHALGAALYLKRDVLAFDPYSSRVERLDPTKALARRMWLVKEASNTKTVALVDGHEGQARPGLVRALKEM
AEKAGMRVRVYKSLILTREFVLNLPEEVVVTLSCPRLALDDFGDVREKVVLAPGEFRAAVLGLDSYAFPF

Sequences:

>Translated_310_residues
MRYVLDEEKVKAFIKEVKPSKVLVEAPPGLFKPAKRVCELVSVECEISAMPVFGGCLAYEFLEGDAIIHLGHNPYPWWTP
KKPTLYLEVPVEVETDVEVVKDKLKGKRVVLGAVVQHLNLLDELKERLRGWGFEPLTFTSKGLKEGQVLGCDYRNLRRGY
DDYLIVAGGRFHALGAALYLKRDVLAFDPYSSRVERLDPTKALARRMWLVKEASNTKTVALVDGHEGQARPGLVRALKEM
AEKAGMRVRVYKSLILTREFVLNLPEEVVVTLSCPRLALDDFGDVREKVVLAPGEFRAAVLGLDSYAFPF
>Mature_310_residues
MRYVLDEEKVKAFIKEVKPSKVLVEAPPGLFKPAKRVCELVSVECEISAMPVFGGCLAYEFLEGDAIIHLGHNPYPWWTP
KKPTLYLEVPVEVETDVEVVKDKLKGKRVVLGAVVQHLNLLDELKERLRGWGFEPLTFTSKGLKEGQVLGCDYRNLRRGY
DDYLIVAGGRFHALGAALYLKRDVLAFDPYSSRVERLDPTKALARRMWLVKEASNTKTVALVDGHEGQARPGLVRALKEM
AEKAGMRVRVYKSLILTREFVLNLPEEVVVTLSCPRLALDDFGDVREKVVLAPGEFRAAVLGLDSYAFPF

Specific function: Unknown

COG id: COG1736

COG function: function code J; Diphthamide synthase subunit DPH2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI116686106, Length=308, Percent_Identity=26.6233766233766, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17552166, Length=331, Percent_Identity=23.8670694864048, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322088, Length=310, Percent_Identity=24.5161290322581, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24662841, Length=325, Percent_Identity=23.6923076923077, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356957, Length=325, Percent_Identity=23.6923076923077, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 34829; Mature: 34829

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVLDEEKVKAFIKEVKPSKVLVEAPPGLFKPAKRVCELVSVECEISAMPVFGGCLAYE
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHH
FLEGDAIIHLGHNPYPWWTPKKPTLYLEVPVEVETDVEVVKDKLKGKRVVLGAVVQHLNL
EECCCEEEEECCCCCCCCCCCCCEEEEEECCEECCCHHHHHHHHCCCEEHHHHHHHHHHH
LDELKERLRGWGFEPLTFTSKGLKEGQVLGCDYRNLRRGYDDYLIVAGGRFHALGAALYL
HHHHHHHHHCCCCCCCEECCCCCCCCCEECCCHHHHHCCCCCEEEEECCCHHHHHHHHHH
KRDVLAFDPYSSRVERLDPTKALARRMWLVKEASNTKTVALVDGHEGQARPGLVRALKEM
HHHHEEECCHHHHHHHCCHHHHHHHHHHHHEECCCCEEEEEEECCCCCCCCHHHHHHHHH
AEKAGMRVRVYKSLILTREFVLNLPEEVVVTLSCPRLALDDFGDVREKVVLAPGEFRAAV
HHHCCCEEEHHHHHHHHHHHHHCCCCHHEEEECCCCHHHHHHHHHHHEEEECCCCCEEEE
LGLDSYAFPF
EECCCCCCCC
>Mature Secondary Structure
MRYVLDEEKVKAFIKEVKPSKVLVEAPPGLFKPAKRVCELVSVECEISAMPVFGGCLAYE
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHH
FLEGDAIIHLGHNPYPWWTPKKPTLYLEVPVEVETDVEVVKDKLKGKRVVLGAVVQHLNL
EECCCEEEEECCCCCCCCCCCCCEEEEEECCEECCCHHHHHHHHCCCEEHHHHHHHHHHH
LDELKERLRGWGFEPLTFTSKGLKEGQVLGCDYRNLRRGYDDYLIVAGGRFHALGAALYL
HHHHHHHHHCCCCCCCEECCCCCCCCCEECCCHHHHHCCCCCEEEEECCCHHHHHHHHHH
KRDVLAFDPYSSRVERLDPTKALARRMWLVKEASNTKTVALVDGHEGQARPGLVRALKEM
HHHHEEECCHHHHHHHCCHHHHHHHHHHHHEECCCCEEEEEEECCCCCCCCHHHHHHHHH
AEKAGMRVRVYKSLILTREFVLNLPEEVVVTLSCPRLALDDFGDVREKVVLAPGEFRAAV
HHHCCCEEEHHHHHHHHHHHHHCCCCHHEEEECCCCHHHHHHHHHHHEEEECCCCCEEEE
LGLDSYAFPF
EECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA