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The map label for this gene is ribD [C]

Identifier: 156937747

GI number: 156937747

Start: 847334

End: 847999

Strand: Reverse

Name: ribD [C]

Synonym: Igni_0956

Alternate gene names: 156937747

Gene position: 847999-847334 (Counterclockwise)

Preceding gene: 156937751

Following gene: 156937746

Centisome position: 65.35

GC content: 55.86

Gene sequence:

>666_bases
GTGATAGAAGTCGTCATATTTTCCACCGCCAGTTTGGACGGCAGAATAGCCACCAAGTCCGGAGACTCCAAACTCTCTTG
TGAAAACGACCTAAGGCTCCTCCACAAGTGGCGCTGCTGGTCCGACTTGGTCTTGGTTGGAGCGAACACTGCTAAGACGG
ACGACCCCGGACTTTTCGTGAAGAGGGTGCCGTGCAAACGTCAACCCTTGAGGGGGGTAGTGGACGGGAGGCTCTCGGTC
CCACACGACCTAAGGCTGTTCCGGGAGTGGCCGTGGACCAGCTTGGTCGTTACAACTGTCGAAGGTATAAGGAATAACGA
GTGGAAGTACAAGTACTTTAAGTCGTTGGGCGTCGAGGTGCTCGTCGCCGGAAAGGGGCCCGAGGTGGACTGGGGGAGGG
CGCTGGAAGAGCTGGGCTCTAAGGGGGTGAGGAAGGTCTTAGTTGAAGGGGGCGGAAGGCTTAACTGGAGCTTGCTGAAA
TATGTGAATACCTTGGAAATAACGTACGTAGGCAAAGTCTTGGGCGCCGGGACGAACTTGTTCGAAGGGGAGGGCTTCGA
AAGGGTAGACGAGTCGCCGGACTTCGAGCCCTCCGCGGCTAAGTTCTGCGAGTGCGGTAGGTGTATTCACGTAACCTGGA
CTCGGAAACTGCACACCTCAATTTAA

Upstream 100 bases:

>100_bases
CAAAGCTAAGCACGAAGACGTCTTCCCGGTTCCGTTAATTCCCCCCAAGAAGATCACGGATATTCTTACCCCTTAGAGCG
ACGTTAGAAAGGGGTTTTGT

Downstream 100 bases:

>100_bases
AGTGGTTTAATGGCTGAGCAACCAGCAAACTTCGCCCCGAGCCATGCCCTATATGGAAGACATTTTTTAACGCCCTGAAA
GTCCTCCCAACCGAGGAGAG

Product: 2, 5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one reductase

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MIEVVIFSTASLDGRIATKSGDSKLSCENDLRLLHKWRCWSDLVLVGANTAKTDDPGLFVKRVPCKRQPLRGVVDGRLSV
PHDLRLFREWPWTSLVVTTVEGIRNNEWKYKYFKSLGVEVLVAGKGPEVDWGRALEELGSKGVRKVLVEGGGRLNWSLLK
YVNTLEITYVGKVLGAGTNLFEGEGFERVDESPDFEPSAAKFCECGRCIHVTWTRKLHTSI

Sequences:

>Translated_221_residues
MIEVVIFSTASLDGRIATKSGDSKLSCENDLRLLHKWRCWSDLVLVGANTAKTDDPGLFVKRVPCKRQPLRGVVDGRLSV
PHDLRLFREWPWTSLVVTTVEGIRNNEWKYKYFKSLGVEVLVAGKGPEVDWGRALEELGSKGVRKVLVEGGGRLNWSLLK
YVNTLEITYVGKVLGAGTNLFEGEGFERVDESPDFEPSAAKFCECGRCIHVTWTRKLHTSI
>Mature_221_residues
MIEVVIFSTASLDGRIATKSGDSKLSCENDLRLLHKWRCWSDLVLVGANTAKTDDPGLFVKRVPCKRQPLRGVVDGRLSV
PHDLRLFREWPWTSLVVTTVEGIRNNEWKYKYFKSLGVEVLVAGKGPEVDWGRALEELGSKGVRKVLVEGGGRLNWSLLK
YVNTLEITYVGKVLGAGTNLFEGEGFERVDESPDFEPSAAKFCECGRCIHVTWTRKLHTSI

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004794
- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 24780; Mature: 24780

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVVIFSTASLDGRIATKSGDSKLSCENDLRLLHKWRCWSDLVLVGANTAKTDDPGLFV
CEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEE
KRVPCKRQPLRGVVDGRLSVPHDLRLFREWPWTSLVVTTVEGIRNNEWKYKYFKSLGVEV
EECCCCCCCCCHHCCCCCCCCHHHHHHHCCCCCEEEEEEHHHHCCCCCHHHHHHHCCEEE
LVAGKGPEVDWGRALEELGSKGVRKVLVEGGGRLNWSLLKYVNTLEITYVGKVLGAGTNL
EEECCCCCCHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHHEEEEEEHHHHCCCCCC
FEGEGFERVDESPDFEPSAAKFCECGRCIHVTWTRKLHTSI
CCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECEECCCC
>Mature Secondary Structure
MIEVVIFSTASLDGRIATKSGDSKLSCENDLRLLHKWRCWSDLVLVGANTAKTDDPGLFV
CEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEE
KRVPCKRQPLRGVVDGRLSVPHDLRLFREWPWTSLVVTTVEGIRNNEWKYKYFKSLGVEV
EECCCCCCCCCHHCCCCCCCCHHHHHHHCCCCCEEEEEEHHHHCCCCCHHHHHHHCCEEE
LVAGKGPEVDWGRALEELGSKGVRKVLVEGGGRLNWSLLKYVNTLEITYVGKVLGAGTNL
EEECCCCCCHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHHEEEEEEHHHHCCCCCC
FEGEGFERVDESPDFEPSAAKFCECGRCIHVTWTRKLHTSI
CCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEECEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]