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The map label for this gene is argD [H]

Identifier: 156937735

GI number: 156937735

Start: 837927

End: 839087

Strand: Direct

Name: argD [H]

Synonym: Igni_0944

Alternate gene names: 156937735

Gene position: 837927-839087 (Clockwise)

Preceding gene: 156937733

Following gene: 156937736

Centisome position: 64.58

GC content: 57.19

Gene sequence:

>1161_bases
TTGAACGCCAGGCTTTTACGGTTCTACCCGCCCAGAGGCTTGAAGATCGTGAAGGCCTACATGCAGTACGTGTGGGACGA
CAAGTGGAACAAGTATTTGGACTACTACAACGGATACGGGGTAGGCTTCTTAGGGCATAGAAACCCGAGGGTGGTCGCCA
AGATCGTAGAGCAGTTGGGGACCCTCATGATAAATTCCCCCTCGTTCGACGACCCCGCGAAGGAGGAATTGATGGCAAAG
CTTCCCAAAATCTTGCCTAATACGTTGCTCAACGTTTACTTCCAGAACTCCGGGGCCGAAGCAGTAGAGTTGGCGCTCAA
GCTGGCTTTACATTATACTAATAGGGAGAAGGTGGTAGCCTTCAAGAGGGCCTTCCACGGGAGGACTCTGGGAGCCCTCA
GCCTGACGTGGGGCTCCGAGTACCGCAAGCCCTCCGAGAGGGCGCTGTACAAGAACGTCGTGTTCGCGGACTTCAACTCC
GTCGAGGAGCTCGATAAGGTAATAGATGAGAACACAGCCGCAGTTTTCGTGGAGCCCGTCCAGGGCGAGGGCGGCATAAA
CCCTGCCACGCCGGAGTTCATGAACGCCGTAGCGAGGAGGGCTAGGGAGGTCGGCGCGGTCCTAGTTTACGACGAGGTGC
AAGCCGGCTTCGGGAGGACCGGTTACGTGTGGGCCTACCAAGGGCTGGGGGCCCCCGACCCCGACGTACTTCTGAGCGGG
AAGGCCATAGGCAACGGCTACCCGGTATCCATGGTGGCGGTTTCCGACAAGATAGCTGAGAGTGTTGTGCCCGGGATGCA
CGGCTCCACCTACGGCGCTAACCCCGTGGCGCTGGCGGCGGTGAGCGGGGCGGTGGACGTGCTCCTAGAAGACGAAGTCC
CAAAGCAAGCTAGGGAGAAGGGCAAACTCTTCCAAGAGATGCTCGAGGAAAAGTTGAAGGACGTCAAGCTCGTTCGGGAC
TACAGAGCTATAGGCCTAATGGTCGGCGTAGAGCTCCGCGTCAAGCCCGGCAAGTACATAGAGGCCTTGCAGAGGGAAGG
CGTGCTGAGCTTGAAGGCCGGTACGACAGTAATAAGGTTCTTACCGCCGTACGTGACGACCTCCGAAGATATTAATTTCG
CAACGGAGAGACTAAGGAAGGTGTTAGTTAGTGGAGTTTGA

Upstream 100 bases:

>100_bases
CTTCATTTCGTCGCTCAGGCCCAAGGCCTTCCACTCGAAAGCTACTTAGCCCTAGAGCCCTTGAAAACCCCACGCCGGAC
CCCTCGAGGGCGCTGAAGTC

Downstream 100 bases:

>100_bases
AGTAAGGCTGCCCTACCCACTTACGCTCGCGAAGAGGGGCAACAAGAGGCTCGTGCTGTTCTTGGAAAAACCGGTGGTAA
TTATAAATACGGAGAGGCCG

Product: N2-acetyl-L-lysine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNARLLRFYPPRGLKIVKAYMQYVWDDKWNKYLDYYNGYGVGFLGHRNPRVVAKIVEQLGTLMINSPSFDDPAKEELMAK
LPKILPNTLLNVYFQNSGAEAVELALKLALHYTNREKVVAFKRAFHGRTLGALSLTWGSEYRKPSERALYKNVVFADFNS
VEELDKVIDENTAAVFVEPVQGEGGINPATPEFMNAVARRAREVGAVLVYDEVQAGFGRTGYVWAYQGLGAPDPDVLLSG
KAIGNGYPVSMVAVSDKIAESVVPGMHGSTYGANPVALAAVSGAVDVLLEDEVPKQAREKGKLFQEMLEEKLKDVKLVRD
YRAIGLMVGVELRVKPGKYIEALQREGVLSLKAGTTVIRFLPPYVTTSEDINFATERLRKVLVSGV

Sequences:

>Translated_386_residues
MNARLLRFYPPRGLKIVKAYMQYVWDDKWNKYLDYYNGYGVGFLGHRNPRVVAKIVEQLGTLMINSPSFDDPAKEELMAK
LPKILPNTLLNVYFQNSGAEAVELALKLALHYTNREKVVAFKRAFHGRTLGALSLTWGSEYRKPSERALYKNVVFADFNS
VEELDKVIDENTAAVFVEPVQGEGGINPATPEFMNAVARRAREVGAVLVYDEVQAGFGRTGYVWAYQGLGAPDPDVLLSG
KAIGNGYPVSMVAVSDKIAESVVPGMHGSTYGANPVALAAVSGAVDVLLEDEVPKQAREKGKLFQEMLEEKLKDVKLVRD
YRAIGLMVGVELRVKPGKYIEALQREGVLSLKAGTTVIRFLPPYVTTSEDINFATERLRKVLVSGV
>Mature_386_residues
MNARLLRFYPPRGLKIVKAYMQYVWDDKWNKYLDYYNGYGVGFLGHRNPRVVAKIVEQLGTLMINSPSFDDPAKEELMAK
LPKILPNTLLNVYFQNSGAEAVELALKLALHYTNREKVVAFKRAFHGRTLGALSLTWGSEYRKPSERALYKNVVFADFNS
VEELDKVIDENTAAVFVEPVQGEGGINPATPEFMNAVARRAREVGAVLVYDEVQAGFGRTGYVWAYQGLGAPDPDVLLSG
KAIGNGYPVSMVAVSDKIAESVVPGMHGSTYGANPVALAAVSGAVDVLLEDEVPKQAREKGKLFQEMLEEKLKDVKLVRD
YRAIGLMVGVELRVKPGKYIEALQREGVLSLKAGTTVIRFLPPYVTTSEDINFATERLRKVLVSGV

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=30.5288461538462, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI13994255, Length=428, Percent_Identity=27.803738317757, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI24119277, Length=419, Percent_Identity=30.3102625298329, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=29.8076923076923, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=30, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI4557809, Length=400, Percent_Identity=29, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI284507298, Length=307, Percent_Identity=29.9674267100977, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI188536080, Length=402, Percent_Identity=24.1293532338308, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679950, Length=402, Percent_Identity=24.1293532338308, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679946, Length=402, Percent_Identity=24.1293532338308, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789759, Length=389, Percent_Identity=35.73264781491, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1788044, Length=385, Percent_Identity=31.1688311688312, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI145693181, Length=381, Percent_Identity=33.0708661417323, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787560, Length=410, Percent_Identity=30.4878048780488, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789016, Length=414, Percent_Identity=28.9855072463768, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1786349, Length=330, Percent_Identity=28.7878787878788, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786991, Length=388, Percent_Identity=25.5154639175258, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=399, Percent_Identity=30.3258145363409, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI32564660, Length=423, Percent_Identity=29.0780141843972, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=29.8165137614679, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25144274, Length=276, Percent_Identity=30.7971014492754, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=429, Percent_Identity=26.8065268065268, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71992985, Length=123, Percent_Identity=36.5853658536585, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=31.8877551020408, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6323470, Length=405, Percent_Identity=29.6296296296296, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=415, Percent_Identity=26.2650602409639, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=283, Percent_Identity=28.2685512367491, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI161085790, Length=432, Percent_Identity=29.1666666666667, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI28574759, Length=428, Percent_Identity=29.4392523364486, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI21357415, Length=400, Percent_Identity=29.75, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI21356575, Length=419, Percent_Identity=27.4463007159904, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=27.4647887323944, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=27.4647887323944, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=27.4647887323944, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42696; Mature: 42696

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARLLRFYPPRGLKIVKAYMQYVWDDKWNKYLDYYNGYGVGFLGHRNPRVVAKIVEQLG
CCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHH
TLMINSPSFDDPAKEELMAKLPKILPNTLLNVYFQNSGAEAVELALKLALHYTNREKVVA
HEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHH
FKRAFHGRTLGALSLTWGSEYRKPSERALYKNVVFADFNSVEELDKVIDENTAAVFVEPV
HHHHHCCCCEEEEEEECCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEE
QGEGGINPATPEFMNAVARRAREVGAVLVYDEVQAGFGRTGYVWAYQGLGAPDPDVLLSG
CCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECHHCCCCCCCEEEEECCCCCCCCCEEEEC
KAIGNGYPVSMVAVSDKIAESVVPGMHGSTYGANPVALAAVSGAVDVLLEDEVPKQAREK
CCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHEEECCCCCHHHHHH
GKLFQEMLEEKLKDVKLVRDYRAIGLMVGVELRVKPGKYIEALQREGVLSLKAGTTVIRF
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHCCCEEEECCCEEEEE
LPPYVTTSEDINFATERLRKVLVSGV
CCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNARLLRFYPPRGLKIVKAYMQYVWDDKWNKYLDYYNGYGVGFLGHRNPRVVAKIVEQLG
CCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHH
TLMINSPSFDDPAKEELMAKLPKILPNTLLNVYFQNSGAEAVELALKLALHYTNREKVVA
HEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHH
FKRAFHGRTLGALSLTWGSEYRKPSERALYKNVVFADFNSVEELDKVIDENTAAVFVEPV
HHHHHCCCCEEEEEEECCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEE
QGEGGINPATPEFMNAVARRAREVGAVLVYDEVQAGFGRTGYVWAYQGLGAPDPDVLLSG
CCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECHHCCCCCCCEEEEECCCCCCCCCEEEEC
KAIGNGYPVSMVAVSDKIAESVVPGMHGSTYGANPVALAAVSGAVDVLLEDEVPKQAREK
CCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHEEECCCCCHHHHHH
GKLFQEMLEEKLKDVKLVRDYRAIGLMVGVELRVKPGKYIEALQREGVLSLKAGTTVIRF
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHCCCEEEECCCEEEEE
LPPYVTTSEDINFATERLRKVLVSGV
CCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]