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The map label for this gene is dxs [C]

Identifier: 156937684

GI number: 156937684

Start: 790840

End: 791790

Strand: Direct

Name: dxs [C]

Synonym: Igni_0891

Alternate gene names: 156937684

Gene position: 790840-791790 (Clockwise)

Preceding gene: 156937682

Following gene: 156937685

Centisome position: 60.95

GC content: 58.04

Gene sequence:

>951_bases
GTGGGAGAAGTGATGAACGAGTCGCCCCGTAACGCGTTCGGCGAGCAGTTGGTCAAGGAGGGGGAGAAGAGGAAGGACTT
GGTGGTGCTAACCGCCGACGTGGCCGACGCCACGAGGACGAAGTGGTTCGCCGAGAAGTTCCCAGAAAGGTTCATCAATG
TTGGCATTTCCGAACAAAACATGATAGGGATGAGTGCCGGCTTAGCGGCCGTGGGCTTCCAGCCGCTGGTGGCGGCCTTC
GCGATGTTCTTGATGAGGGCTTGGGAGCAAGTTAGGAATACGGTCTGTAGGGCCCACGTTAACGTGAAGATAGTGGGCAC
CCACGCCGGCTTCTCCGACGCCGGCGACGGCTCCTCCCACCAAGTGCTAGAAGACGTGGCCCTCATGAGGACGTTGCCCT
GTATGAGCGTGGTGGTGCCGGCGGACGCCACCGAGATAAGGAAGGCCTTGCCGGAGGTGTTGGACTACCCTACGCCAGTT
TACATGAGGATAGGAAGAGACTACGGTCCTAAGGTGTACAGCGACAACAACTACGAGTTCAGAGTTGGGGAGGCGGTCTG
GCTCAAGGACGGTTACGACTTCGCGATAATAGGCAACGGCCCCTTGCTGTGGGACGCCTTGGTGGCGGCCGAAAAGCTCG
AGAAGGAAGGGACCAGCGTCGCAGTGATAAACATGCATACGGTGAAGCCTCTGGACACCAAGACGTTAGACAAAGTGGCG
GGGAAGTACTCCGGCATAGTTACTGTGGAAGAGCACGGCGTCAGGGGAGGGCTCGGCTCGGCGGTGGCGGAGTACTTGGT
CCAGACCTCTCCGGTGCCCATGGAGATACTCGGCGCCCGCTCGTTCGGAAAGTCAGCCCGAGACGTGAGACACATTATAA
TTGCGAACGGACTCGACTTTACCTCTATAATCAACGCTGTGAAAAGGCTCGAGAGGAGGGTTAGAAGATGA

Upstream 100 bases:

>100_bases
TTCCAGCGGTAGGCCCACCCGGAGGTGCCCACGTGCACTTTCATGGCGACGCTGGGGCCCCTCCCTCGCTGGAACTATAA
AGGGCTTTGGTGGGTCCGGG

Downstream 100 bases:

>100_bases
GCGAGAACCCGCTCGAGTCCCTTAAGGTTAAGAGGAGAGAACTCGACAAGCTCGATAAAGAGATATTAAGGCTGCTCAAG
AGGAGGTTCGAAATCGTCAA

Product: transketolase subunit B

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGEVMNESPRNAFGEQLVKEGEKRKDLVVLTADVADATRTKWFAEKFPERFINVGISEQNMIGMSAGLAAVGFQPLVAAF
AMFLMRAWEQVRNTVCRAHVNVKIVGTHAGFSDAGDGSSHQVLEDVALMRTLPCMSVVVPADATEIRKALPEVLDYPTPV
YMRIGRDYGPKVYSDNNYEFRVGEAVWLKDGYDFAIIGNGPLLWDALVAAEKLEKEGTSVAVINMHTVKPLDTKTLDKVA
GKYSGIVTVEEHGVRGGLGSAVAEYLVQTSPVPMEILGARSFGKSARDVRHIIIANGLDFTSIINAVKRLERRVRR

Sequences:

>Translated_316_residues
MGEVMNESPRNAFGEQLVKEGEKRKDLVVLTADVADATRTKWFAEKFPERFINVGISEQNMIGMSAGLAAVGFQPLVAAF
AMFLMRAWEQVRNTVCRAHVNVKIVGTHAGFSDAGDGSSHQVLEDVALMRTLPCMSVVVPADATEIRKALPEVLDYPTPV
YMRIGRDYGPKVYSDNNYEFRVGEAVWLKDGYDFAIIGNGPLLWDALVAAEKLEKEGTSVAVINMHTVKPLDTKTLDKVA
GKYSGIVTVEEHGVRGGLGSAVAEYLVQTSPVPMEILGARSFGKSARDVRHIIIANGLDFTSIINAVKRLERRVRR
>Mature_315_residues
GEVMNESPRNAFGEQLVKEGEKRKDLVVLTADVADATRTKWFAEKFPERFINVGISEQNMIGMSAGLAAVGFQPLVAAFA
MFLMRAWEQVRNTVCRAHVNVKIVGTHAGFSDAGDGSSHQVLEDVALMRTLPCMSVVVPADATEIRKALPEVLDYPTPVY
MRIGRDYGPKVYSDNNYEFRVGEAVWLKDGYDFAIIGNGPLLWDALVAAEKLEKEGTSVAVINMHTVKPLDTKTLDKVAG
KYSGIVTVEEHGVRGGLGSAVAEYLVQTSPVPMEILGARSFGKSARDVRHIIIANGLDFTSIINAVKRLERRVRR

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=305, Percent_Identity=33.1147540983607, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI4507521, Length=305, Percent_Identity=33.1147540983607, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI225637463, Length=300, Percent_Identity=32.6666666666667, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI225637459, Length=300, Percent_Identity=32.6666666666667, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI225637461, Length=300, Percent_Identity=32.6666666666667, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI133778974, Length=300, Percent_Identity=31.3333333333333, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI291084858, Length=275, Percent_Identity=22.5454545454545, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI156564403, Length=281, Percent_Identity=23.4875444839858, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786622, Length=272, Percent_Identity=31.6176470588235, Blast_Score=130, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17539652, Length=311, Percent_Identity=33.7620578778135, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6319698, Length=277, Percent_Identity=25.2707581227437, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45551847, Length=265, Percent_Identity=35.0943396226415, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45550715, Length=265, Percent_Identity=35.0943396226415, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24645119, Length=265, Percent_Identity=35.0943396226415, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24666278, Length=265, Percent_Identity=33.2075471698113, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21358145, Length=233, Percent_Identity=25.3218884120172, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650940, Length=233, Percent_Identity=25.3218884120172, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 34682; Mature: 34551

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEVMNESPRNAFGEQLVKEGEKRKDLVVLTADVADATRTKWFAEKFPERFINVGISEQN
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCC
MIGMSAGLAAVGFQPLVAAFAMFLMRAWEQVRNTVCRAHVNVKIVGTHAGFSDAGDGSSH
CCCHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHH
QVLEDVALMRTLPCMSVVVPADATEIRKALPEVLDYPTPVYMRIGRDYGPKVYSDNNYEF
HHHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEE
RVGEAVWLKDGYDFAIIGNGPLLWDALVAAEKLEKEGTSVAVINMHTVKPLDTKTLDKVA
EECCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHH
GKYSGIVTVEEHGVRGGLGSAVAEYLVQTSPVPMEILGARSFGKSARDVRHIIIANGLDF
HHHCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHCCHHCCCHHHHHEEEEEECCCCH
TSIINAVKRLERRVRR
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GEVMNESPRNAFGEQLVKEGEKRKDLVVLTADVADATRTKWFAEKFPERFINVGISEQN
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCC
MIGMSAGLAAVGFQPLVAAFAMFLMRAWEQVRNTVCRAHVNVKIVGTHAGFSDAGDGSSH
CCCHHHCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHH
QVLEDVALMRTLPCMSVVVPADATEIRKALPEVLDYPTPVYMRIGRDYGPKVYSDNNYEF
HHHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEE
RVGEAVWLKDGYDFAIIGNGPLLWDALVAAEKLEKEGTSVAVINMHTVKPLDTKTLDKVA
EECCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHH
GKYSGIVTVEEHGVRGGLGSAVAEYLVQTSPVPMEILGARSFGKSARDVRHIIIANGLDF
HHHCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHCCHHCCCHHHHHEEEEEECCCCH
TSIINAVKRLERRVRR
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]