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The map label for this gene is ppa [H]

Identifier: 156937673

GI number: 156937673

Start: 780951

End: 781514

Strand: Direct

Name: ppa [H]

Synonym: Igni_0880

Alternate gene names: 156937673

Gene position: 780951-781514 (Clockwise)

Preceding gene: 156937672

Following gene: 156937674

Centisome position: 60.19

GC content: 53.01

Gene sequence:

>564_bases
TTGAGTTTAGAGAAGCTGGGTCCCGGGAAGGACGCCCCCGAGGTCGTTAACGTAGTGATAGAAATACCTATGGGAGGCTA
CGTCAAGTACGAGATGGACAAAGATACTGGGTTAATAAAGGTGGACAGAGTGCTCTACACCGCTATGTACTACCCCTTCA
ACTACGGCTTCATACCGGGCACGCTGGAAGAGGACGGCGACCCCGTGGACGTCTTGGTCCTGAGCTACGACCCCTTCTAC
CCCGGCACCTACCTAAAAGCCAAGCCGGTCGGCGTGCTCCTCATGGAGGATGAAGAAGGTCCCGACAGCAAGATTATCGC
CGTCCCGGTGGAGAAGGTCGACCCGAGGTTCAAGGACATTAAGGACGTCAACGACATACCACAGATAATAAAGGACAAGA
TAAAACACTTCTTCGAACACTACAAGGAGCTGGAACCCGGCAAGTGGGTCAAGATAAAGGACTGGTTACCGAAGGAGGAA
GCTTACAAGAAAATAAAGGCGGCCATCGACCGGTATCAACAAAATAAGCGCTCGAGCGCCCTAACGAGCGGGCAAGGGCA
GTGA

Upstream 100 bases:

>100_bases
AAAAGGGCCTCCAAGTGAGCTGCGGGCGGGCGGAGCTGTTGGACTGTTTGAGCGAGACGTTGAAAACTCCGTGAGCGAGA
ACAGCTCTCGGGGGACGCTC

Downstream 100 bases:

>100_bases
TAACCTACGACGTACTCATTTTAACTCTCAGCGGAGTGCTGCTCGCCCACGGGTCCTTCGAGGTCCCCGCGGGGGACTTG
TCGTGGACCTTCTTCTACCC

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLEKLGPGKDAPEVVNVVIEIPMGGYVKYEMDKDTGLIKVDRVLYTAMYYPFNYGFIPGTLEEDGDPVDVLVLSYDPFY
PGTYLKAKPVGVLLMEDEEGPDSKIIAVPVEKVDPRFKDIKDVNDIPQIIKDKIKHFFEHYKELEPGKWVKIKDWLPKEE
AYKKIKAAIDRYQQNKRSSALTSGQGQ

Sequences:

>Translated_187_residues
MSLEKLGPGKDAPEVVNVVIEIPMGGYVKYEMDKDTGLIKVDRVLYTAMYYPFNYGFIPGTLEEDGDPVDVLVLSYDPFY
PGTYLKAKPVGVLLMEDEEGPDSKIIAVPVEKVDPRFKDIKDVNDIPQIIKDKIKHFFEHYKELEPGKWVKIKDWLPKEE
AYKKIKAAIDRYQQNKRSSALTSGQGQ
>Mature_186_residues
SLEKLGPGKDAPEVVNVVIEIPMGGYVKYEMDKDTGLIKVDRVLYTAMYYPFNYGFIPGTLEEDGDPVDVLVLSYDPFYP
GTYLKAKPVGVLLMEDEEGPDSKIIAVPVEKVDPRFKDIKDVNDIPQIIKDKIKHFFEHYKELEPGKWVKIKDWLPKEEA
YKKIKAAIDRYQQNKRSSALTSGQGQ

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=175, Percent_Identity=51.4285714285714, Blast_Score=179, Evalue=1e-46,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 21318; Mature: 21187

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEKLGPGKDAPEVVNVVIEIPMGGYVKYEMDKDTGLIKVDRVLYTAMYYPFNYGFIPG
CCCCCCCCCCCCHHHEEEEEECCCCCEEEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCC
TLEEDGDPVDVLVLSYDPFYPGTYLKAKPVGVLLMEDEEGPDSKIIAVPVEKVDPRFKDI
CCCCCCCCEEEEEEECCCCCCCCEEEECCEEEEEEECCCCCCCCEEEEEHHHCCCCHHHH
KDVNDIPQIIKDKIKHFFEHYKELEPGKWVKIKDWLPKEEAYKKIKAAIDRYQQNKRSSA
HCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LTSGQGQ
CCCCCCC
>Mature Secondary Structure 
SLEKLGPGKDAPEVVNVVIEIPMGGYVKYEMDKDTGLIKVDRVLYTAMYYPFNYGFIPG
CCCCCCCCCCCHHHEEEEEECCCCCEEEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCC
TLEEDGDPVDVLVLSYDPFYPGTYLKAKPVGVLLMEDEEGPDSKIIAVPVEKVDPRFKDI
CCCCCCCCEEEEEEECCCCCCCCEEEECCEEEEEEECCCCCCCCEEEEEHHHCCCCHHHH
KDVNDIPQIIKDKIKHFFEHYKELEPGKWVKIKDWLPKEEAYKKIKAAIDRYQQNKRSSA
HCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LTSGQGQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]