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The map label for this gene is asd [H]

Identifier: 156937545

GI number: 156937545

Start: 675711

End: 676790

Strand: Direct

Name: asd [H]

Synonym: Igni_0752

Alternate gene names: 156937545

Gene position: 675711-676790 (Clockwise)

Preceding gene: 156937543

Following gene: 156937547

Centisome position: 52.08

GC content: 52.69

Gene sequence:

>1080_bases
ATGCCCCTAAAGACTAGGGGAAAGGACGTGGACAAGCTCAAGGTTGCTGTCCTAGGGGCTACTGGAATGGCCGGTCAGTG
GTTCGCGTCGTTGCTCGAGGATCACCCTTACTTCGAGTTAGTGGCCTTGGGGGCTTCCAAGAGGTCGGCCGGCAAGAAGT
ATAAGGAAGCTGTAAGGTGGGTCATCCCCCGTCCTTTCCCTACTAAGTTCTCCGACTACGTCGTGTTCGACGCCTCCGAT
CCCGATGCGCTGCCCGAGAAGGTGGACTTGGTGTTCTCCGCGCTCCCCAGCGAAGTGGCAGGAGAAATAGAGTTGAAGTA
CTTGAAGAAGGGATTCAACGTAGTTTCGAACGCCTCACCGTTCAGACTCGAACCCGACGTACCCCTCATGAATCCCGAGA
TCAACTGGGATCACTTAGAACTCTTGAAGAAACAAGAGAGGTGGGGCGGCAAGCTGGTCAAGAACCCCAACTGTACTACG
GCCGTCTTGACGTTACCACTCAAACCGATTATGGATGAGTTCGGTATAAAGGAGATAACTGTAACTACGCTGCAAGCTAT
AAGCGGGGCGGGGTTCGCCGGACTCACGGCTTACTCTATAGTTGACAACGTAATTCCTTATATCGCGAAAGAGGAGTACA
AAGTCAAAGTAGAGTCCAAGAAGATGTTAGGTAAGTTGGAAGGGGACTCTATAAGGCCCGCTGACTTTGTGGTCGAAGCT
ACGACGACCAGGGTTCCAGTCTTAGACGGCCACACGGAAGTGGTTTACATAACTACGAAGAGGAGCGTGGACGTCGAGCA
AGTAAAGGACGTGCTGAAGAGTTTCGAAAGCGAACCCCAGCGTTTGGGGTTACCTACTGCCCCGCCCAAGCCCGTGATCG
TGATGGAACAAGAGGACCGTCCGCAGCCTAGGTTGGACAGAATGAACGGCAACGGGATGGCTGTTACTGTCGGAAGGATA
GAGATAACCGAAACTAATAGAGTTAGGATGGTGATGGTTGGACATAACCTCCTAAGGGGCGCCTCCGGGGTCAGCCTCCT
AACGGCGGAACTCATGTACAAGAAAGGTTACATAACGTAG

Upstream 100 bases:

>100_bases
TTACTCCTGTCCGAGCTCCTTTCCATGAACAAGCTAGTCCTCTGCCTACCTCCCATCCGTCACACCCCGGGAGCCCTAAG
GGGACGGGGATTAAAGGCCC

Downstream 100 bases:

>100_bases
TACTTGCTATAATCTTCGTCCTCTTCGGAGCGCTTGAACAGCTGGGGGCAGAGAGGCTCTTCCTCCTTAACTTTTTTCCT
CTTCTTCTTGGGCCTAACGT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MPLKTRGKDVDKLKVAVLGATGMAGQWFASLLEDHPYFELVALGASKRSAGKKYKEAVRWVIPRPFPTKFSDYVVFDASD
PDALPEKVDLVFSALPSEVAGEIELKYLKKGFNVVSNASPFRLEPDVPLMNPEINWDHLELLKKQERWGGKLVKNPNCTT
AVLTLPLKPIMDEFGIKEITVTTLQAISGAGFAGLTAYSIVDNVIPYIAKEEYKVKVESKKMLGKLEGDSIRPADFVVEA
TTTRVPVLDGHTEVVYITTKRSVDVEQVKDVLKSFESEPQRLGLPTAPPKPVIVMEQEDRPQPRLDRMNGNGMAVTVGRI
EITETNRVRMVMVGHNLLRGASGVSLLTAELMYKKGYIT

Sequences:

>Translated_359_residues
MPLKTRGKDVDKLKVAVLGATGMAGQWFASLLEDHPYFELVALGASKRSAGKKYKEAVRWVIPRPFPTKFSDYVVFDASD
PDALPEKVDLVFSALPSEVAGEIELKYLKKGFNVVSNASPFRLEPDVPLMNPEINWDHLELLKKQERWGGKLVKNPNCTT
AVLTLPLKPIMDEFGIKEITVTTLQAISGAGFAGLTAYSIVDNVIPYIAKEEYKVKVESKKMLGKLEGDSIRPADFVVEA
TTTRVPVLDGHTEVVYITTKRSVDVEQVKDVLKSFESEPQRLGLPTAPPKPVIVMEQEDRPQPRLDRMNGNGMAVTVGRI
EITETNRVRMVMVGHNLLRGASGVSLLTAELMYKKGYIT
>Mature_358_residues
PLKTRGKDVDKLKVAVLGATGMAGQWFASLLEDHPYFELVALGASKRSAGKKYKEAVRWVIPRPFPTKFSDYVVFDASDP
DALPEKVDLVFSALPSEVAGEIELKYLKKGFNVVSNASPFRLEPDVPLMNPEINWDHLELLKKQERWGGKLVKNPNCTTA
VLTLPLKPIMDEFGIKEITVTTLQAISGAGFAGLTAYSIVDNVIPYIAKEEYKVKVESKKMLGKLEGDSIRPADFVVEAT
TTRVPVLDGHTEVVYITTKRSVDVEQVKDVLKSFESEPQRLGLPTAPPKPVIVMEQEDRPQPRLDRMNGNGMAVTVGRIE
ITETNRVRMVMVGHNLLRGASGVSLLTAELMYKKGYIT

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=282, Percent_Identity=25.531914893617, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320362, Length=360, Percent_Identity=42.2222222222222, Blast_Score=263, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39770; Mature: 39638

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKTRGKDVDKLKVAVLGATGMAGQWFASLLEDHPYFELVALGASKRSAGKKYKEAVRW
CCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
VIPRPFPTKFSDYVVFDASDPDALPEKVDLVFSALPSEVAGEIELKYLKKGFNVVSNASP
HCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCCCCC
FRLEPDVPLMNPEINWDHLELLKKQERWGGKLVKNPNCTTAVLTLPLKPIMDEFGIKEIT
EEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCEEEEEECCHHHHHHCCCCEEE
VTTLQAISGAGFAGLTAYSIVDNVIPYIAKEEYKVKVESKKMLGKLEGDSIRPADFVVEA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCCCCCEEEEE
TTTRVPVLDGHTEVVYITTKRSVDVEQVKDVLKSFESEPQRLGLPTAPPKPVIVMEQEDR
CCCEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCEEEECCCCC
PQPRLDRMNGNGMAVTVGRIEITETNRVRMVMVGHNLLRGASGVSLLTAELMYKKGYIT
CCCHHHCCCCCCEEEEEEEEEEECCCCEEEEEECCHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PLKTRGKDVDKLKVAVLGATGMAGQWFASLLEDHPYFELVALGASKRSAGKKYKEAVRW
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
VIPRPFPTKFSDYVVFDASDPDALPEKVDLVFSALPSEVAGEIELKYLKKGFNVVSNASP
HCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCCCCC
FRLEPDVPLMNPEINWDHLELLKKQERWGGKLVKNPNCTTAVLTLPLKPIMDEFGIKEIT
EEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCEEEEEECCHHHHHHCCCCEEE
VTTLQAISGAGFAGLTAYSIVDNVIPYIAKEEYKVKVESKKMLGKLEGDSIRPADFVVEA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCCCCCEEEEE
TTTRVPVLDGHTEVVYITTKRSVDVEQVKDVLKSFESEPQRLGLPTAPPKPVIVMEQEDR
CCCEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCEEEECCCCC
PQPRLDRMNGNGMAVTVGRIEITETNRVRMVMVGHNLLRGASGVSLLTAELMYKKGYIT
CCCHHHCCCCCCEEEEEEEEEEECCCCEEEEEECCHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]