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The map label for this gene is pth [H]

Identifier: 156937513

GI number: 156937513

Start: 649676

End: 649987

Strand: Reverse

Name: pth [H]

Synonym: Igni_0720

Alternate gene names: 156937513

Gene position: 649987-649676 (Counterclockwise)

Preceding gene: 156937514

Following gene: 156937509

Centisome position: 50.09

GC content: 57.69

Gene sequence:

>312_bases
ATGGGGAAGGGAAAGATCTGCGCACAAGTGGCTCACGCTTCCTTAGGAGCGGCCTTGGAGGCTATGAAGAAGAAGCCATC
TTGGTTCGAGGAGTGGACCAAAGGGGGCCAGAAGAAGGTGGTCCTCAAGGTTGGTTCGCTGAAGGAGTTGCTAGAAATAT
ATCAGAAGGCTAGGGACCTCGGCCTCCCCGCGTTCTTGGTTAAGGACGCGGGCCTAACCCAAGTGGAGCCTGGCACCGTA
ACGGCAGTCGCAGTAGGCCCTGCCCCCGAAGAGGAGGTCGACAAGGTTACCGGCCACTTGAAGCTGCTGTAG

Upstream 100 bases:

>100_bases
CGGGCAGAGGTAGTTAGGGCGTTAAAGATGAGCGGAATCGAGGGAGGTAAGCTTGCCGAGAGGCTTCAAGCAGAGCATAG
TGGTGAGGACAGACATTAAA

Downstream 100 bases:

>100_bases
GGCCCTTCTGGGGGGAGGAGGGTCTTTAACGGCTCCTACGCCTCAACAGTCTTGGAGTAATCAACCTTGTCGGGAGTATC
CAAGTCTGAGTGGTAGATCT

Product: peptidyl-tRNA hydrolase

Products: NA

Alternate protein names: PTH [H]

Number of amino acids: Translated: 103; Mature: 102

Protein sequence:

>103_residues
MGKGKICAQVAHASLGAALEAMKKKPSWFEEWTKGGQKKVVLKVGSLKELLEIYQKARDLGLPAFLVKDAGLTQVEPGTV
TAVAVGPAPEEEVDKVTGHLKLL

Sequences:

>Translated_103_residues
MGKGKICAQVAHASLGAALEAMKKKPSWFEEWTKGGQKKVVLKVGSLKELLEIYQKARDLGLPAFLVKDAGLTQVEPGTV
TAVAVGPAPEEEVDKVTGHLKLL
>Mature_102_residues
GKGKICAQVAHASLGAALEAMKKKPSWFEEWTKGGQKKVVLKVGSLKELLEIYQKARDLGLPAFLVKDAGLTQVEPGTVT
AVAVGPAPEEEVDKVTGHLKLL

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis [H]

COG id: COG1990

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH2 family [H]

Homologues:

Organism=Homo sapiens, GI7706351, Length=102, Percent_Identity=43.1372549019608, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17558188, Length=105, Percent_Identity=42.8571428571429, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319414, Length=108, Percent_Identity=37.962962962963, Blast_Score=75, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281376919, Length=103, Percent_Identity=43.6893203883495, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644665, Length=103, Percent_Identity=43.6893203883495, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646438, Length=106, Percent_Identity=40.5660377358491, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002833 [H]

Pfam domain/function: PF01981 PTH2 [H]

EC number: =3.1.1.29 [H]

Molecular weight: Translated: 10979; Mature: 10848

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGKICAQVAHASLGAALEAMKKKPSWFEEWTKGGQKKVVLKVGSLKELLEIYQKARDL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHC
GLPAFLVKDAGLTQVEPGTVTAVAVGPAPEEEVDKVTGHLKLL
CCCEEEECCCCCCEECCCCEEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKGKICAQVAHASLGAALEAMKKKPSWFEEWTKGGQKKVVLKVGSLKELLEIYQKARDL
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHC
GLPAFLVKDAGLTQVEPGTVTAVAVGPAPEEEVDKVTGHLKLL
CCCEEEECCCCCCEECCCCEEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]