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The map label for this gene is nadA [H]

Identifier: 156937434

GI number: 156937434

Start: 577842

End: 578762

Strand: Reverse

Name: nadA [H]

Synonym: Igni_0641

Alternate gene names: 156937434

Gene position: 578762-577842 (Counterclockwise)

Preceding gene: 156937436

Following gene: 156937432

Centisome position: 44.6

GC content: 56.68

Gene sequence:

>921_bases
ATGATTGACGAACTGATGAGAAAGGTTGAGGAACTGAAGAGGCGGCGCAGGGCTTTCATCATAGCGCACAACTACCAGCT
CCCGGAAGTTCAAGAGGTAGCGGACTTCGTTGGGGACAGCCTAGAAATGGCTATGAAGGCCGAGGAGGTCGACGCGGACG
TCATAGTAGTTGCTGGGGTCAGGTTCATGGCCGAGGTAGCGAAGCTTCTAAACCCCGACAGAGTAGTCCTGCACCCCGAG
CCTCGGGCCGGGTGTCCTCTGGCGGACCACATGACGCCGGAGATAATCAAGCGGTTCAGAGAGAACTACCCGCACGCGCC
GCTGGTAACTTACGTCAATTCCAGCGTAGAAGCGAAAGCCTTGAGCGACTACGTAGTCACCAGCGCGTCGGCGGTCAAAG
TGGTCTCCAAGCTAGAGGACGAGGTAGTTTTGTTCGGGCCCGACAAGAACTTAGCCAAGTTCGTTGCCCACAGAACGAAT
AAGGACATAATAGCAGTGCCCCCTTGGGGCCACTGCCCGGTCCACGAGTTCTTGGTCTCCCCGTACTACTTGAGGAAGGC
AAAGGAGAGGCACCCCCATTGCAAGCTCTTGGTCCACCCCGAGGCGCCGTGGGAGAGCCAGAAGATGGCTGACTTCGTGG
GAAGCACGAGTCAGATGCTGAGAGCTATAGGGGAGCTCGGCGCTAAGTGTTACATACTGGGGACGGAAGAGGGCTTGAGT
TACAGGGCGAAAAAGATGTACCCCCACGTGGAGGTATACCCTCCCGACGCCCGCACTATATGCATAGATATGAAGAAGAT
AACTCTAGACAAGATAGTTAGGGCGTTGGAGACGCTGAAGCCCCAAGTGGTCTTGGACGAGGAGGTTGCCAAGAGGGCTA
GGGAGGCGGTGGTCAGAGGCCTCGAGCTGGCGAGGTCTTGA

Upstream 100 bases:

>100_bases
AACGCCTTGAGCCTGTCGTTGCTCAAAACTGTCTACCGTGGTAGCCTTTAGGCTGAAGGTTTTAAAGAAATTAAACCGTG
CGGGTGCTTGGGTCTGCTAG

Downstream 100 bases:

>100_bases
GCCTCTTCCTACCCTCCTCCCTAACCTTCTCTAGGTCGACCTTGTCCAAGCCTCCCTTAGCCACTACGTCCCTCTCCAAG
TCCAGCTCCGTGTAGACCCC

Product: quinolinate synthetase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MIDELMRKVEELKRRRRAFIIAHNYQLPEVQEVADFVGDSLEMAMKAEEVDADVIVVAGVRFMAEVAKLLNPDRVVLHPE
PRAGCPLADHMTPEIIKRFRENYPHAPLVTYVNSSVEAKALSDYVVTSASAVKVVSKLEDEVVLFGPDKNLAKFVAHRTN
KDIIAVPPWGHCPVHEFLVSPYYLRKAKERHPHCKLLVHPEAPWESQKMADFVGSTSQMLRAIGELGAKCYILGTEEGLS
YRAKKMYPHVEVYPPDARTICIDMKKITLDKIVRALETLKPQVVLDEEVAKRAREAVVRGLELARS

Sequences:

>Translated_306_residues
MIDELMRKVEELKRRRRAFIIAHNYQLPEVQEVADFVGDSLEMAMKAEEVDADVIVVAGVRFMAEVAKLLNPDRVVLHPE
PRAGCPLADHMTPEIIKRFRENYPHAPLVTYVNSSVEAKALSDYVVTSASAVKVVSKLEDEVVLFGPDKNLAKFVAHRTN
KDIIAVPPWGHCPVHEFLVSPYYLRKAKERHPHCKLLVHPEAPWESQKMADFVGSTSQMLRAIGELGAKCYILGTEEGLS
YRAKKMYPHVEVYPPDARTICIDMKKITLDKIVRALETLKPQVVLDEEVAKRAREAVVRGLELARS
>Mature_306_residues
MIDELMRKVEELKRRRRAFIIAHNYQLPEVQEVADFVGDSLEMAMKAEEVDADVIVVAGVRFMAEVAKLLNPDRVVLHPE
PRAGCPLADHMTPEIIKRFRENYPHAPLVTYVNSSVEAKALSDYVVTSASAVKVVSKLEDEVVLFGPDKNLAKFVAHRTN
KDIIAVPPWGHCPVHEFLVSPYYLRKAKERHPHCKLLVHPEAPWESQKMADFVGSTSQMLRAIGELGAKCYILGTEEGLS
YRAKKMYPHVEVYPPDARTICIDMKKITLDKIVRALETLKPQVVLDEEVAKRAREAVVRGLELARS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=317, Percent_Identity=35.0157728706625, Blast_Score=157, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34570; Mature: 34570

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDELMRKVEELKRRRRAFIIAHNYQLPEVQEVADFVGDSLEMAMKAEEVDADVIVVAGV
CHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHH
RFMAEVAKLLNPDRVVLHPEPRAGCPLADHMTPEIIKRFRENYPHAPLVTYVNSSVEAKA
HHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCHHHHCCCCHHHH
LSDYVVTSASAVKVVSKLEDEVVLFGPDKNLAKFVAHRTNKDIIAVPPWGHCPVHEFLVS
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHC
PYYLRKAKERHPHCKLLVHPEAPWESQKMADFVGSTSQMLRAIGELGAKCYILGTEEGLS
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCH
YRAKKMYPHVEVYPPDARTICIDMKKITLDKIVRALETLKPQVVLDEEVAKRAREAVVRG
HHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHH
LELARS
HHHHCC
>Mature Secondary Structure
MIDELMRKVEELKRRRRAFIIAHNYQLPEVQEVADFVGDSLEMAMKAEEVDADVIVVAGV
CHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHH
RFMAEVAKLLNPDRVVLHPEPRAGCPLADHMTPEIIKRFRENYPHAPLVTYVNSSVEAKA
HHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCHHHHCCCCHHHH
LSDYVVTSASAVKVVSKLEDEVVLFGPDKNLAKFVAHRTNKDIIAVPPWGHCPVHEFLVS
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHC
PYYLRKAKERHPHCKLLVHPEAPWESQKMADFVGSTSQMLRAIGELGAKCYILGTEEGLS
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCH
YRAKKMYPHVEVYPPDARTICIDMKKITLDKIVRALETLKPQVVLDEEVAKRAREAVVRG
HHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHH
LELARS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA