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The map label for this gene is glyS [H]

Identifier: 156937361

GI number: 156937361

Start: 510811

End: 512553

Strand: Reverse

Name: glyS [H]

Synonym: Igni_0568

Alternate gene names: 156937361

Gene position: 512553-510811 (Counterclockwise)

Preceding gene: 156937362

Following gene: 156937360

Centisome position: 39.5

GC content: 57.83

Gene sequence:

>1743_bases
TTGCAAGACAAGGCCTCGAAGGTGGCCGACCTAGCCCAGAGGAGGGGCTTCTACTGGCCCTCTTGGGAGATCTACGGCGG
CGTGGCCGGCTTCTACGACCTGGGTCCTTTGGGCAAGGAACTGAAGAACAAGATTGTTGAGTTGTGGAAGGAGAAGCTGG
TAAGGCCCCTTCAAAGGATGGTAGTAGAAATGGAGACCCCAATAATCACGCCCTACAAGGTGTTGGAGGCGTCCGGGCAC
GTCGAGAACTTCACCGACCCGGTGGTGGAGTGTAAGTCGTGCGGGAGGAAGTTCCGCGCCGACCACTTGATAGAGGAAAA
GCTGGGGATAAAGGTAGAAGGCCTCAGCCCCGAGGACTTAACCAAACTCATTAGAGAGAATAACATAAGGTGTCCGGTGT
GCGGCGGCGAGTTGGGGGAGGTCCGCCCGTTCTTGCTGCTCTTCCAGACCCAGATAGGCCCTTACGAAGGCGACAAGGGC
TTCATAAGGCCGGAGACCGCCCAAGGCGCCTTCGTCAACTTCAAGCGCGTATACCAATACATGAGGGAGAGGCTCCCCTT
CGGGATAGCGCAGATAGGCAGAGTAGGGAGGAACGAGATATCTCCCCGTCAAGGGTTGTTGAGGCTTAGGGAGTTCACAA
TAGCTGAGATAGAGTTCTTCATCGACCCCTTGGACCCCGGCGAACCTCCGTTGGACTACGACGCCAAGCTGAGGCTCCTG
CCTTGGGAGCTAGCTAAGGAGGGGAGGAAAGAGCCCGTGGAGGTGACGGTCAGAGAAGCCTTGGAGAAGGGATGGATAAT
AAACAAGTGGATGGCTTATTGGATGTTGAAGGCCAAGGAGCTGTTAAACGAGTTGGGCGTACCCGACGAGAACCAGTACT
TCGAGGAGAAAGGGCCGGAGGAGAGGGCCCACTACTCCTCCCAGACGTACGACCAGTTGGTGAAGACTGAACGCTACGGC
TGGATGGAGGTCAGCGGCCACGCCTACCGGGGCGACTACGACTTAAGTAGGCACATAAAGTTCAGCGGCAAGGATCTGTA
CGCCTTCAGGAAGTACAAGGAGCCTAAGGTCGTTAAGGTAAAGGTAGTGAAGTGGAACGCAAAAGAAATAGGTATAAGGT
TGAAGGCCAAGGCGAAGCAAGTGATAGAGGAGCTGAAGAGGATGAACCCCGAAGAGGTGGAGAAGAGCTTGGAGGAGAAG
GGCTACGTCGAGGTGGCGGGCGAGAGGTTGGAAAGGGGCTTGGTGTGGGTAGAGGAGGCGGAGGAGAAGGTGACCGGAGA
GCGCTTCGTGCCCCACGTCGTGGAGCCCTCCTTCGGCGTGGAGAGGTTGTTGTACGTCACCTTAGAGTACGCCTTGAAGG
AGAGGGAGGGGAGGCTAGTGCTGAGCTTGCCCCGGAGGCTAGCTCCAATAGAAGCGGTGGTGCTGCCGCTCTTAGAAGAG
AAGCCGTTGGTCGAGAAGGCCAAGGAGGTCTGGAAGCTCTTGGCCGACGCGGGCTTCCGCGTGGAGTACGACGAGAAGGG
TTCGATAGGGCGGAGGTACGCGAGGTACGACGAGGTGGGCGTGCCGGCGGCCATAACGGTGGACTTCCAGACCCTTGAGG
ACAACACCGTAACGCTGAGGGACAGGGACACGTGGAAGCAAGTACGCGTAAGGGTCGAGGAGCTCCCGGGGAAGCTGAGG
GCCTTCTTGAACGGCTTCCCTATAGAGGAGCTCGGGGAGCCCGTCTCGGCCGGGCCCCAATGA

Upstream 100 bases:

>100_bases
CAGCGCAACGCTCAACAAAGGGCCGTAGTAACGCTTCTTCACTCGTCCGGTCCCCGAGGTGAATATATGCTCCGCTTAAA
CCCCCTTCGGGGACGCGGAA

Downstream 100 bases:

>100_bases
AGGTCGCGGTTTTGCTCGTAGCCGGGAGACCCAACCTCGAGGCCGCCTTTTCCTCGGTTAGGGTCTTGGAGGAGCTGGGC
GCGGAGGAGGTAACAATAGT

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MQDKASKVADLAQRRGFYWPSWEIYGGVAGFYDLGPLGKELKNKIVELWKEKLVRPLQRMVVEMETPIITPYKVLEASGH
VENFTDPVVECKSCGRKFRADHLIEEKLGIKVEGLSPEDLTKLIRENNIRCPVCGGELGEVRPFLLLFQTQIGPYEGDKG
FIRPETAQGAFVNFKRVYQYMRERLPFGIAQIGRVGRNEISPRQGLLRLREFTIAEIEFFIDPLDPGEPPLDYDAKLRLL
PWELAKEGRKEPVEVTVREALEKGWIINKWMAYWMLKAKELLNELGVPDENQYFEEKGPEERAHYSSQTYDQLVKTERYG
WMEVSGHAYRGDYDLSRHIKFSGKDLYAFRKYKEPKVVKVKVVKWNAKEIGIRLKAKAKQVIEELKRMNPEEVEKSLEEK
GYVEVAGERLERGLVWVEEAEEKVTGERFVPHVVEPSFGVERLLYVTLEYALKEREGRLVLSLPRRLAPIEAVVLPLLEE
KPLVEKAKEVWKLLADAGFRVEYDEKGSIGRRYARYDEVGVPAAITVDFQTLEDNTVTLRDRDTWKQVRVRVEELPGKLR
AFLNGFPIEELGEPVSAGPQ

Sequences:

>Translated_580_residues
MQDKASKVADLAQRRGFYWPSWEIYGGVAGFYDLGPLGKELKNKIVELWKEKLVRPLQRMVVEMETPIITPYKVLEASGH
VENFTDPVVECKSCGRKFRADHLIEEKLGIKVEGLSPEDLTKLIRENNIRCPVCGGELGEVRPFLLLFQTQIGPYEGDKG
FIRPETAQGAFVNFKRVYQYMRERLPFGIAQIGRVGRNEISPRQGLLRLREFTIAEIEFFIDPLDPGEPPLDYDAKLRLL
PWELAKEGRKEPVEVTVREALEKGWIINKWMAYWMLKAKELLNELGVPDENQYFEEKGPEERAHYSSQTYDQLVKTERYG
WMEVSGHAYRGDYDLSRHIKFSGKDLYAFRKYKEPKVVKVKVVKWNAKEIGIRLKAKAKQVIEELKRMNPEEVEKSLEEK
GYVEVAGERLERGLVWVEEAEEKVTGERFVPHVVEPSFGVERLLYVTLEYALKEREGRLVLSLPRRLAPIEAVVLPLLEE
KPLVEKAKEVWKLLADAGFRVEYDEKGSIGRRYARYDEVGVPAAITVDFQTLEDNTVTLRDRDTWKQVRVRVEELPGKLR
AFLNGFPIEELGEPVSAGPQ
>Mature_580_residues
MQDKASKVADLAQRRGFYWPSWEIYGGVAGFYDLGPLGKELKNKIVELWKEKLVRPLQRMVVEMETPIITPYKVLEASGH
VENFTDPVVECKSCGRKFRADHLIEEKLGIKVEGLSPEDLTKLIRENNIRCPVCGGELGEVRPFLLLFQTQIGPYEGDKG
FIRPETAQGAFVNFKRVYQYMRERLPFGIAQIGRVGRNEISPRQGLLRLREFTIAEIEFFIDPLDPGEPPLDYDAKLRLL
PWELAKEGRKEPVEVTVREALEKGWIINKWMAYWMLKAKELLNELGVPDENQYFEEKGPEERAHYSSQTYDQLVKTERYG
WMEVSGHAYRGDYDLSRHIKFSGKDLYAFRKYKEPKVVKVKVVKWNAKEIGIRLKAKAKQVIEELKRMNPEEVEKSLEEK
GYVEVAGERLERGLVWVEEAEEKVTGERFVPHVVEPSFGVERLLYVTLEYALKEREGRLVLSLPRRLAPIEAVVLPLLEE
KPLVEKAKEVWKLLADAGFRVEYDEKGSIGRRYARYDEVGVPAAITVDFQTLEDNTVTLRDRDTWKQVRVRVEELPGKLR
AFLNGFPIEELGEPVSAGPQ

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=594, Percent_Identity=36.1952861952862, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI32564541, Length=584, Percent_Identity=36.472602739726, Blast_Score=357, Evalue=7e-99,
Organism=Caenorhabditis elegans, GI17554996, Length=588, Percent_Identity=36.5646258503401, Blast_Score=357, Evalue=8e-99,
Organism=Saccharomyces cerevisiae, GI6325338, Length=594, Percent_Identity=34.6801346801347, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319597, Length=629, Percent_Identity=34.4992050874404, Blast_Score=348, Evalue=9e-97,
Organism=Drosophila melanogaster, GI21357965, Length=578, Percent_Identity=38.4083044982699, Blast_Score=385, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24664462, Length=578, Percent_Identity=38.4083044982699, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022960
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 66958; Mature: 66958

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKASKVADLAQRRGFYWPSWEIYGGVAGFYDLGPLGKELKNKIVELWKEKLVRPLQRM
CCCHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VVEMETPIITPYKVLEASGHVENFTDPVVECKSCGRKFRADHLIEEKLGIKVEGLSPEDL
HHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHHH
TKLIRENNIRCPVCGGELGEVRPFLLLFQTQIGPYEGDKGFIRPETAQGAFVNFKRVYQY
HHHHHHCCCEEEECCCCCHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
MRERLPFGIAQIGRVGRNEISPRQGLLRLREFTIAEIEFFIDPLDPGEPPLDYDAKLRLL
HHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEEE
PWELAKEGRKEPVEVTVREALEKGWIINKWMAYWMLKAKELLNELGVPDENQYFEEKGPE
CHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCH
ERAHYSSQTYDQLVKTERYGWMEVSGHAYRGDYDLSRHIKFSGKDLYAFRKYKEPKVVKV
HHHHCCHHHHHHHHHHHCCCEEEECCCEECCCCCCCCCEEECCCHHHHHHHCCCCCEEEE
KVVKWNAKEIGIRLKAKAKQVIEELKRMNPEEVEKSLEEKGYVEVAGERLERGLVWVEEA
EEEEECHHHHCEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEHHH
EEKVTGERFVPHVVEPSFGVERLLYVTLEYALKEREGRLVLSLPRRLAPIEAVVLPLLEE
HHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHCCHHHHHHHHHCC
KPLVEKAKEVWKLLADAGFRVEYDEKGSIGRRYARYDEVGVPAAITVDFQTLEDNTVTLR
CCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCEEEEE
DRDTWKQVRVRVEELPGKLRAFLNGFPIEELGEPVSAGPQ
CCHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MQDKASKVADLAQRRGFYWPSWEIYGGVAGFYDLGPLGKELKNKIVELWKEKLVRPLQRM
CCCHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VVEMETPIITPYKVLEASGHVENFTDPVVECKSCGRKFRADHLIEEKLGIKVEGLSPEDL
HHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHHH
TKLIRENNIRCPVCGGELGEVRPFLLLFQTQIGPYEGDKGFIRPETAQGAFVNFKRVYQY
HHHHHHCCCEEEECCCCCHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
MRERLPFGIAQIGRVGRNEISPRQGLLRLREFTIAEIEFFIDPLDPGEPPLDYDAKLRLL
HHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEEE
PWELAKEGRKEPVEVTVREALEKGWIINKWMAYWMLKAKELLNELGVPDENQYFEEKGPE
CHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCH
ERAHYSSQTYDQLVKTERYGWMEVSGHAYRGDYDLSRHIKFSGKDLYAFRKYKEPKVVKV
HHHHCCHHHHHHHHHHHCCCEEEECCCEECCCCCCCCCEEECCCHHHHHHHCCCCCEEEE
KVVKWNAKEIGIRLKAKAKQVIEELKRMNPEEVEKSLEEKGYVEVAGERLERGLVWVEEA
EEEEECHHHHCEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEHHH
EEKVTGERFVPHVVEPSFGVERLLYVTLEYALKEREGRLVLSLPRRLAPIEAVVLPLLEE
HHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHCCHHHHHHHHHCC
KPLVEKAKEVWKLLADAGFRVEYDEKGSIGRRYARYDEVGVPAAITVDFQTLEDNTVTLR
CCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCEEEEE
DRDTWKQVRVRVEELPGKLRAFLNGFPIEELGEPVSAGPQ
CCHHHHHHHHHHHHCCHHHHHHHCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]