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The map label for this gene is lolD [H]

Identifier: 156937343

GI number: 156937343

Start: 494708

End: 495295

Strand: Direct

Name: lolD [H]

Synonym: Igni_0550

Alternate gene names: 156937343

Gene position: 494708-495295 (Clockwise)

Preceding gene: 156937342

Following gene: 156937347

Centisome position: 38.13

GC content: 57.99

Gene sequence:

>588_bases
GTGAGGTTCGGGAAGAGGGTCGTGGTCGAAGAGCAAGAAGTGCTAATTGAGAGGGGCGTGAGCTGTTTGGTTGGCCCCTC
CGGGCTGGGGAAGAGCACCTTCCTCAAACAACTCCTAAAGGAGCTTTCTTGGCCTTACGTGCCTCAAGAGCTGAAGTTCC
CTCCCGGGAGGGTCGCGGAGCTGGCGGCCCACTTAGCTTCCCTGAACCACTGCGCGAGCCCCCGTACGTACCTCAAGAAC
TTCGTTGAATTGATGGGAGAGCTCAACCTAGGCCCGGAGTACCTCCACAAGGGCGTTTGGGAGCTCAGCTCGGGGGAGAG
ACAGAGGGTCGCAGTAGCCTTGCAGCTGGCCAGGGGGTGCTGCTCTCTGCTCGCCGACGAGCCCACCTCCCAACTCGACC
CGCAGAACTCCGCAAAACTTATGGACACTATAAAGAAGAGGACTAAGGTTTCCTTCGTGGTGACCCACGACCCCGTGGCC
TTGGGCTTCTGCGACCGCGTCTTCACGCTGAGGGAAGGGGTATTGGTAGAAGAGGTAATCTCAAAGGACTGTTTGGAGGG
GTGCGTTAGATGTTTCCTACCCTCTTAA

Upstream 100 bases:

>100_bases
GGGAGGCCCTCGTCGGCCTCTTAATAGTCACGGTTCTGAAGGCCTTAGTAGTTGTGAACAACTCGATAAACGCCTACCTA
GTCGTGTTAAAGTTAAGGAA

Downstream 100 bases:

>100_bases
ACTTATCTTTGGACTTGAGGGGGGCGGTGGCGTCGAGCCCCATCTTGCTAGTCAAGCCGTCTTGTGAGCTCGGGTCCAAG
GAGGAGCCCCGGGCGTTCTT

Product: ABC transporter

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MRFGKRVVVEEQEVLIERGVSCLVGPSGLGKSTFLKQLLKELSWPYVPQELKFPPGRVAELAAHLASLNHCASPRTYLKN
FVELMGELNLGPEYLHKGVWELSSGERQRVAVALQLARGCCSLLADEPTSQLDPQNSAKLMDTIKKRTKVSFVVTHDPVA
LGFCDRVFTLREGVLVEEVISKDCLEGCVRCFLPS

Sequences:

>Translated_195_residues
MRFGKRVVVEEQEVLIERGVSCLVGPSGLGKSTFLKQLLKELSWPYVPQELKFPPGRVAELAAHLASLNHCASPRTYLKN
FVELMGELNLGPEYLHKGVWELSSGERQRVAVALQLARGCCSLLADEPTSQLDPQNSAKLMDTIKKRTKVSFVVTHDPVA
LGFCDRVFTLREGVLVEEVISKDCLEGCVRCFLPS
>Mature_195_residues
MRFGKRVVVEEQEVLIERGVSCLVGPSGLGKSTFLKQLLKELSWPYVPQELKFPPGRVAELAAHLASLNHCASPRTYLKN
FVELMGELNLGPEYLHKGVWELSSGERQRVAVALQLARGCCSLLADEPTSQLDPQNSAKLMDTIKKRTKVSFVVTHDPVA
LGFCDRVFTLREGVLVEEVISKDCLEGCVRCFLPS

Specific function: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-de

COG id: COG1126

COG function: function code E; ABC-type polar amino acid transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015854
- InterPro:   IPR003593
- InterPro:   IPR011924 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 21641; Mature: 21641

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFGKRVVVEEQEVLIERGVSCLVGPSGLGKSTFLKQLLKELSWPYVPQELKFPPGRVAE
CCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCHHHH
LAAHLASLNHCASPRTYLKNFVELMGELNLGPEYLHKGVWELSSGERQRVAVALQLARGC
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
CSLLADEPTSQLDPQNSAKLMDTIKKRTKVSFVVTHDPVALGFCDRVFTLREGVLVEEVI
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCHHHHHHH
SKDCLEGCVRCFLPS
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFGKRVVVEEQEVLIERGVSCLVGPSGLGKSTFLKQLLKELSWPYVPQELKFPPGRVAE
CCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCCHHHH
LAAHLASLNHCASPRTYLKNFVELMGELNLGPEYLHKGVWELSSGERQRVAVALQLARGC
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
CSLLADEPTSQLDPQNSAKLMDTIKKRTKVSFVVTHDPVALGFCDRVFTLREGVLVEEVI
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCHHHHHHH
SKDCLEGCVRCFLPS
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA