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The map label for this gene is hypE [C]

Identifier: 156937284

GI number: 156937284

Start: 438199

End: 439212

Strand: Direct

Name: hypE [C]

Synonym: Igni_0490

Alternate gene names: 156937284

Gene position: 438199-439212 (Clockwise)

Preceding gene: 156937282

Following gene: 156937287

Centisome position: 33.77

GC content: 60.26

Gene sequence:

>1014_bases
TTGAGCGTTACCCTAGCGGTCGGGGGAGGAGGGAGGGAAACCGAAGAGTTCATCAAGAACTTCATACTTCCCTTGTTCAA
GATAAGGAGCTTGGGGAGCGTGGGCCTGGACGACTTGGAGGACGGGGCCGCGGTCCCCATAGGGGACAACAAGTACTTAG
TGGTCTCCGTGGACAGCTATACTGTCAGCCCCCCGTTCTTCCCTGGGGGCGACATAGGCAAGCTCGCCGCTACGGGCTCC
CTCAACGACGTCGCAGTAATGGGCGCAGAGCCCAAAGCGCTTATGGACGCCATAATAGTTGAGGAGGGGTTCAAGTTAAG
CGACTTAAAGACGATATTGAAATCTATGTCCGAAGTTACGAACTCCCTAAACGTGGCGCTGCTCGGAGGGGACACTAAGG
TCATGCCAAAGGGCAGCGTAGATAAAATAGTCATCTCGACCGTCGGTATAGGGATAGCAGAAGGACCCTTGCTGACCTTA
GACCGGGGGGAGCCGGGGGACAAGGTCCTAGTCACCGGGCCGGTGGGCGACCACGGCGCCACCATCCTCGCCCTCCAGTT
CGGCCTACAAGTGAAGACGCTGAAGAGCGACGTCAGGCCGGTGTGGCCAGCAGTTAAGGCGTTGAGGGAAGCGTTGGGCG
AGGACTTGAAGGCCGCTAAGGACCCCACCAGAGGGGGCTTGGCTATGGCTCTCAACGAGCTCGCGGAGAGGAGCAAGACC
ACAGTATACGTCGAGGAGGCTAGGGTGCCGATAAGGGAGGCCGTCAAGGAGTACGCGGAGATGCTGGGGGTGGAGCCCCT
GGCCTTGGCCAGCGAGGGGCAAGCGGTCTTCGTAGTTAAGGGGGACAGAGCGGAGGAGGCGCTGGAGGTCTTGAGGAAGG
CGGGCTTCGAGGAGGCCGCGATAATAGGGGAGCTGAGGAAGGGCAAGCCCGGCTACGTGATATCGCGCACCCCCGTCGGC
GGGCTGAGGCTCTTGGAGAAGCCCAGCGGGGAGCTGGTGCCTAGGATTTGTTGA

Upstream 100 bases:

>100_bases
CGTAGCCGTGGAACACAGCCGCCTTCACTCACCGCGCCCGCCGGGGGGCTGGCGAGTACAATATAACGTTTTGTCGTAGC
CGACCGCTGGGACCCAAGCC

Downstream 100 bases:

>100_bases
ACTACCTAGGCTCCTTCCGGAGGACTTCCTTCACCTCCAAGTACGGCGCCGACCCCCGCGCCACCGCCTTCGCTATCGCT
ACGACCTCCTCCGGCTCGGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSVTLAVGGGGRETEEFIKNFILPLFKIRSLGSVGLDDLEDGAAVPIGDNKYLVVSVDSYTVSPPFFPGGDIGKLAATGS
LNDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMSEVTNSLNVALLGGDTKVMPKGSVDKIVISTVGIGIAEGPLLTL
DRGEPGDKVLVTGPVGDHGATILALQFGLQVKTLKSDVRPVWPAVKALREALGEDLKAAKDPTRGGLAMALNELAERSKT
TVYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKAGFEEAAIIGELRKGKPGYVISRTPVG
GLRLLEKPSGELVPRIC

Sequences:

>Translated_337_residues
MSVTLAVGGGGRETEEFIKNFILPLFKIRSLGSVGLDDLEDGAAVPIGDNKYLVVSVDSYTVSPPFFPGGDIGKLAATGS
LNDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMSEVTNSLNVALLGGDTKVMPKGSVDKIVISTVGIGIAEGPLLTL
DRGEPGDKVLVTGPVGDHGATILALQFGLQVKTLKSDVRPVWPAVKALREALGEDLKAAKDPTRGGLAMALNELAERSKT
TVYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKAGFEEAAIIGELRKGKPGYVISRTPVG
GLRLLEKPSGELVPRIC
>Mature_336_residues
SVTLAVGGGGRETEEFIKNFILPLFKIRSLGSVGLDDLEDGAAVPIGDNKYLVVSVDSYTVSPPFFPGGDIGKLAATGSL
NDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMSEVTNSLNVALLGGDTKVMPKGSVDKIVISTVGIGIAEGPLLTLD
RGEPGDKVLVTGPVGDHGATILALQFGLQVKTLKSDVRPVWPAVKALREALGEDLKAAKDPTRGGLAMALNELAERSKTT
VYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKAGFEEAAIIGELRKGKPGYVISRTPVGG
LRLLEKPSGELVPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=349, Percent_Identity=37.5358166189112, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1786619, Length=233, Percent_Identity=28.3261802575107, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35470; Mature: 35338

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTLAVGGGGRETEEFIKNFILPLFKIRSLGSVGLDDLEDGAAVPIGDNKYLVVSVDSY
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECCE
TVSPPFFPGGDIGKLAATGSLNDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMSEVT
EECCCCCCCCCCCCEEECCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NSLNVALLGGDTKVMPKGSVDKIVISTVGIGIAEGPLLTLDRGEPGDKVLVTGPVGDHGA
CCCEEEEECCCEEECCCCCCCEEEEEHHCCCCCCCCEEEECCCCCCCEEEEECCCCCCCC
TILALQFGLQVKTLKSDVRPVWPAVKALREALGEDLKAAKDPTRGGLAMALNELAERSKT
EEEEEEECCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
TVYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKAGFEEAA
EEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHHHHHCCCHHHH
IIGELRKGKPGYVISRTPVGGLRLLEKPSGELVPRIC
HHHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
SVTLAVGGGGRETEEFIKNFILPLFKIRSLGSVGLDDLEDGAAVPIGDNKYLVVSVDSY
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECCE
TVSPPFFPGGDIGKLAATGSLNDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMSEVT
EECCCCCCCCCCCCEEECCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NSLNVALLGGDTKVMPKGSVDKIVISTVGIGIAEGPLLTLDRGEPGDKVLVTGPVGDHGA
CCCEEEEECCCEEECCCCCCCEEEEEHHCCCCCCCCEEEECCCCCCCEEEEECCCCCCCC
TILALQFGLQVKTLKSDVRPVWPAVKALREALGEDLKAAKDPTRGGLAMALNELAERSKT
EEEEEEECCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
TVYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKAGFEEAA
EEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHHHHHCCCHHHH
IIGELRKGKPGYVISRTPVGGLRLLEKPSGELVPRIC
HHHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]