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The map label for this gene is paaK [H]

Identifier: 156937269

GI number: 156937269

Start: 421334

End: 422815

Strand: Direct

Name: paaK [H]

Synonym: Igni_0475

Alternate gene names: 156937269

Gene position: 421334-422815 (Clockwise)

Preceding gene: 156937264

Following gene: 156937270

Centisome position: 32.47

GC content: 60.05

Gene sequence:

>1482_bases
GTGCTTAGCGGTAGAGCAGTCGTGTTCGAGCGCTACTCGAGGGCCACCCCCCTCGGGGCGTACTTGGAGGAAGGGCGGAG
GTTCAGGGAAGAGGGCTTCATAAGGACGGACTACCCCCCTAAGAGGGACGAGGTCCTCTGGAACCCCAAAATTATGAGGA
TGCCCAGGGAAGAGCTGGAGAAGATAAAGACCCAGAGGCTCAAGGCCATAGTTAAGTGGGCGTGGGAGCACAGCGAGTTC
TACCGCAAGTTCTGGAAGAGCAAGGGCTTCCACCCGGACATGATAAAGACTCACGAGGACGTGGTCAAGATACCGGTCCT
CACCAAGAAGGACTTGAGAGCGGACTTGCAGAAGAACCCGCCTTACGGCACCATAATGGTTCCGGAACTGGCCAAGTACA
TACACTTCGTGGGCGCCACCTCCGGCAGCACCGGGATGCCCACCTTCCAAGGCTGGGGCAGGGTGGAGCTGGACTACTTC
GAGGAACAGCAAGCTAGGTACTTGTGGACCTTCGCCGGCGTCAAGCCCGGCGTAGTCTATGCGAACTACCTCAACATGAG
CGGCTTCTACAGCTGGGGCCCGCCCCTCGTGGAGACCGCCATGTGGAGGTGCGGCGCCACCGCCATCGCCGGCGGGGGCG
AGACCTTCTTCACTTGGAAGGACAGGCACATGCTAATAATGAAGCTGTGGAAGGTTGACGTCTTCGCCACCACCCCGTGG
CTCCACCGCTGGATAGGCGAGCAAGCCAAGCTGGAGGGCTGGGTGACCCCGTTCAAGGTGCTCTTGCTCCACGGAGGGGC
AGCGGCCGAGAAGACCAAGGAGAAGCTGATGGAGGTCCACCCCAACGTCGAGAAGGTCATAAGCGTCTGGGGCACTACGG
ACGGTCACATGGCAATCGAGCCCCCCGACGCGCCCGGGACCTTGGTGTTCTGGGAGGACACCCAGATCTTCGACATAGTG
GTGCCCGGCAGCTACGAGGAGAGGCCCGAGGGCGAGCCGGCGGGCCAGGGCGAGAGGGGAGAGCTCATAGCCACCTTGCT
GACCCACTACACCATGCCCTTGATAAGGTACAGCCTGGGCGACTACGTGAAGAACGAGTTCATATGCGACCCCACCCCGG
AGCTGGGCATAACCCACTGTAGGTTCGCCGAGCTCATACCGGGCAGAGTGGAGTGGATGTTCAAGGTAAAGGGCAAGCTG
CTCTTCCCCATAGTGGTCGAGAACGCGGTGAGCCAGATACCGGACACCACCGGCGCCTACAACATAGTAGTTTACGACGA
CAACATGGACAAGCTGAAGATAAAGGTGGAGACCAGGAAGCCCATACCGCCCCCTCCGGAGTACGACAAGGAGGCAAGGG
AGATCATAGCGAGGGAGCTCGGCCTGAGCCCGGAGGACGTGGAGATAGAGTGGATAAGGCCCGGCGAGAGCGTCTGGAAG
GGCTACAAGCTGCAAGTGTTCTTGGACGAGAGGAAGAAGTAA

Upstream 100 bases:

>100_bases
TTCAGTCAGACGGTTTCCGAAGGGAAAGTTTCAAGCGTAACGCTCAAATAATCCGAGTATATGCCGGTCAATACATGCCT
ATAAACCGCCCCGGCCCTCC

Downstream 100 bases:

>100_bases
GCTTTTTCCACTCTCAGACGTTTATGACCTTACTCCCCTCACCCCCTCCGGGCAGCCGGCCTTGGACGAGCTGGAAAAGT
ACGTAGAGATGTTGGAGAAG

Product: coenzyme F390 synthetase-like protein

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MLSGRAVVFERYSRATPLGAYLEEGRRFREEGFIRTDYPPKRDEVLWNPKIMRMPREELEKIKTQRLKAIVKWAWEHSEF
YRKFWKSKGFHPDMIKTHEDVVKIPVLTKKDLRADLQKNPPYGTIMVPELAKYIHFVGATSGSTGMPTFQGWGRVELDYF
EEQQARYLWTFAGVKPGVVYANYLNMSGFYSWGPPLVETAMWRCGATAIAGGGETFFTWKDRHMLIMKLWKVDVFATTPW
LHRWIGEQAKLEGWVTPFKVLLLHGGAAAEKTKEKLMEVHPNVEKVISVWGTTDGHMAIEPPDAPGTLVFWEDTQIFDIV
VPGSYEERPEGEPAGQGERGELIATLLTHYTMPLIRYSLGDYVKNEFICDPTPELGITHCRFAELIPGRVEWMFKVKGKL
LFPIVVENAVSQIPDTTGAYNIVVYDDNMDKLKIKVETRKPIPPPPEYDKEAREIIARELGLSPEDVEIEWIRPGESVWK
GYKLQVFLDERKK

Sequences:

>Translated_493_residues
MLSGRAVVFERYSRATPLGAYLEEGRRFREEGFIRTDYPPKRDEVLWNPKIMRMPREELEKIKTQRLKAIVKWAWEHSEF
YRKFWKSKGFHPDMIKTHEDVVKIPVLTKKDLRADLQKNPPYGTIMVPELAKYIHFVGATSGSTGMPTFQGWGRVELDYF
EEQQARYLWTFAGVKPGVVYANYLNMSGFYSWGPPLVETAMWRCGATAIAGGGETFFTWKDRHMLIMKLWKVDVFATTPW
LHRWIGEQAKLEGWVTPFKVLLLHGGAAAEKTKEKLMEVHPNVEKVISVWGTTDGHMAIEPPDAPGTLVFWEDTQIFDIV
VPGSYEERPEGEPAGQGERGELIATLLTHYTMPLIRYSLGDYVKNEFICDPTPELGITHCRFAELIPGRVEWMFKVKGKL
LFPIVVENAVSQIPDTTGAYNIVVYDDNMDKLKIKVETRKPIPPPPEYDKEAREIIARELGLSPEDVEIEWIRPGESVWK
GYKLQVFLDERKK
>Mature_493_residues
MLSGRAVVFERYSRATPLGAYLEEGRRFREEGFIRTDYPPKRDEVLWNPKIMRMPREELEKIKTQRLKAIVKWAWEHSEF
YRKFWKSKGFHPDMIKTHEDVVKIPVLTKKDLRADLQKNPPYGTIMVPELAKYIHFVGATSGSTGMPTFQGWGRVELDYF
EEQQARYLWTFAGVKPGVVYANYLNMSGFYSWGPPLVETAMWRCGATAIAGGGETFFTWKDRHMLIMKLWKVDVFATTPW
LHRWIGEQAKLEGWVTPFKVLLLHGGAAAEKTKEKLMEVHPNVEKVISVWGTTDGHMAIEPPDAPGTLVFWEDTQIFDIV
VPGSYEERPEGEPAGQGERGELIATLLTHYTMPLIRYSLGDYVKNEFICDPTPELGITHCRFAELIPGRVEWMFKVKGKL
LFPIVVENAVSQIPDTTGAYNIVVYDDNMDKLKIKVETRKPIPPPPEYDKEAREIIARELGLSPEDVEIEWIRPGESVWK
GYKLQVFLDERKK

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=395, Percent_Identity=28.3544303797468, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 56818; Mature: 56818

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGRAVVFERYSRATPLGAYLEEGRRFREEGFIRTDYPPKRDEVLWNPKIMRMPREELE
CCCCCEEHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCEEECCHHHCCCHHHHH
KIKTQRLKAIVKWAWEHSEFYRKFWKSKGFHPDMIKTHEDVVKIPVLTKKDLRADLQKNP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEECCCCCHHHHHHHHCCC
PYGTIMVPELAKYIHFVGATSGSTGMPTFQGWGRVELDYFEEQQARYLWTFAGVKPGVVY
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHCCCCEEEEEECCCCCCEEE
ANYLNMSGFYSWGPPLVETAMWRCGATAIAGGGETFFTWKDRHMLIMKLWKVDVFATTPW
EEEECCCCCCCCCCHHHHHHHHHCCCEEEECCCCEEEEECCCCEEEEHHHHHEEEECCHH
LHRWIGEQAKLEGWVTPFKVLLLHGGAAAEKTKEKLMEVHPNVEKVISVWGTTDGHMAIE
HHHHCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEC
PPDAPGTLVFWEDTQIFDIVVPGSYEERPEGEPAGQGERGELIATLLTHYTMPLIRYSLG
CCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DYVKNEFICDPTPELGITHCRFAELIPGRVEWMFKVKGKLLFPIVVENAVSQIPDTTGAY
HHHHCCEECCCCCCCCCCHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHCCCCCCCE
NIVVYDDNMDKLKIKVETRKPIPPPPEYDKEAREIIARELGLSPEDVEIEWIRPGESVWK
EEEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHC
GYKLQVFLDERKK
CEEEEEEECCCCC
>Mature Secondary Structure
MLSGRAVVFERYSRATPLGAYLEEGRRFREEGFIRTDYPPKRDEVLWNPKIMRMPREELE
CCCCCEEHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCEEECCHHHCCCHHHHH
KIKTQRLKAIVKWAWEHSEFYRKFWKSKGFHPDMIKTHEDVVKIPVLTKKDLRADLQKNP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEECCCCCHHHHHHHHCCC
PYGTIMVPELAKYIHFVGATSGSTGMPTFQGWGRVELDYFEEQQARYLWTFAGVKPGVVY
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHCCCCEEEEEECCCCCCEEE
ANYLNMSGFYSWGPPLVETAMWRCGATAIAGGGETFFTWKDRHMLIMKLWKVDVFATTPW
EEEECCCCCCCCCCHHHHHHHHHCCCEEEECCCCEEEEECCCCEEEEHHHHHEEEECCHH
LHRWIGEQAKLEGWVTPFKVLLLHGGAAAEKTKEKLMEVHPNVEKVISVWGTTDGHMAIE
HHHHCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEC
PPDAPGTLVFWEDTQIFDIVVPGSYEERPEGEPAGQGERGELIATLLTHYTMPLIRYSLG
CCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DYVKNEFICDPTPELGITHCRFAELIPGRVEWMFKVKGKLLFPIVVENAVSQIPDTTGAY
HHHHCCEECCCCCCCCCCHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHHCCCCCCCE
NIVVYDDNMDKLKIKVETRKPIPPPPEYDKEAREIIARELGLSPEDVEIEWIRPGESVWK
EEEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHC
GYKLQVFLDERKK
CEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]