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The map label for this gene is hypD [C]

Identifier: 156937207

GI number: 156937207

Start: 365668

End: 366804

Strand: Direct

Name: hypD [C]

Synonym: Igni_0413

Alternate gene names: 156937207

Gene position: 365668-366804 (Clockwise)

Preceding gene: 156937204

Following gene: 156937210

Centisome position: 28.18

GC content: 60.6

Gene sequence:

>1137_bases
ATGACGATCCCCCAAGAGCTCGTCCAGAAGACAGTCGAGGCGATAAGGGGTTTAGCTAAGGAGGCAGTCAAGAAGAAGAA
CAAAGAAGTTATAAAAATTATGCACGTGTGCGGGACCCACGAACACACGGTAACCCACAACGGCTTGAGGTCCTTAATGC
CCCCAGAGGTGGAGCTCATAGCCGGCCCCGGGTGCCCGGTCTGCGTGACCCCCGCTGCGGCGGTGGACGCGCTCATAGAC
CTCTCCTTGAGCGGGGTTAGGGTCTACGCCTACGGGGACGTCTACAAGCTCCCGGGGACAAAGGGCTCTCTGGCGGTGGC
CAAGGCGAGGGGAGGGGACGTCAAGGTCGTTTACGGCTTCTTGGACGCTATAAGGGACGCCAAGCAGTACGGGAAGGAGG
CGGTGTTCTTCGGAGTAGGGTTCGAGACCACGGTAGTCACCGTGGCCGGGCCGATATACGACGGCAGGGTGCCGAAGAAC
TTGAAGGTGCTCTCCGCCTACTTGCTCACCGCCCCCGGGCTCAAGAGGGCTATAGAGGCCCACGAGGCCACCGGGATACC
GCTGGACGGCATAATAGCCCCCGGCCACGTGTCCAGCGTAATAGGCGCGAACGCTTGGAAGTACTTGCCGGAGGAGTTCG
GCTTCCCGACCGTGGTGGCCGGGTTCGAGGCGTACGACTACTTGCTCGCCGTAGCGGAGATACTTAGGCAAATAGTTAGG
GGAGAGGCCAAGCTAGTGAACGAGTACTCTAGGGTGGTGAGGCCGGAAGGCAACGTTACTGCTTGGAGGAAGGTGATGGA
AGTATTCGACGTGGTGGACGCGTATTGGAGGGGGATAGGGGTGTTGCCGGAGAGCGGGCTGGCCTTCAAGGAGAAGTACA
AGGACTACGACGCTGCAGCGGAATACGGGATAGAGATCAAGCCGACTGAGAGGGAGCTGCCCCCGGGCTGCAAGTGCGCG
GAGATAAACTTGGGCATAGCGAAGCCCACGGACTGTCCGTACTTCAAGACCCGCTGTACGCCCACCACCCCCATAGGGCC
TTGCATGGTGAGCGACGAGGGGACTTGCTCCATATGGGCTAGGTTCGGCGGAGGAGGGCTGGTGGAGGAGCTGGCGAGGC
TGGCCGGGATAGAGTGA

Upstream 100 bases:

>100_bases
AACTCTTTTGGGCCTCAGAACTTGCAAGAGGTAAAAGCTGTCGAGGCCGCCGGAAAACAATAAAATTCCCTCGTCGACGC
TCTGCTCCCGAGTGTCCCTC

Downstream 100 bases:

>100_bases
GAGGCCCTCCGACTGGCCTTTCGCTCCTCACCTCTCGGGCGCGGAACTGGTCTTCATCGGGGCTCCTTGGGCAAGGCATA
AACCTTCCCCTTGTACTCTA

Product: hydrogenase formation HypD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTIPQELVQKTVEAIRGLAKEAVKKKNKEVIKIMHVCGTHEHTVTHNGLRSLMPPEVELIAGPGCPVCVTPAAAVDALID
LSLSGVRVYAYGDVYKLPGTKGSLAVAKARGGDVKVVYGFLDAIRDAKQYGKEAVFFGVGFETTVVTVAGPIYDGRVPKN
LKVLSAYLLTAPGLKRAIEAHEATGIPLDGIIAPGHVSSVIGANAWKYLPEEFGFPTVVAGFEAYDYLLAVAEILRQIVR
GEAKLVNEYSRVVRPEGNVTAWRKVMEVFDVVDAYWRGIGVLPESGLAFKEKYKDYDAAAEYGIEIKPTERELPPGCKCA
EINLGIAKPTDCPYFKTRCTPTTPIGPCMVSDEGTCSIWARFGGGGLVEELARLAGIE

Sequences:

>Translated_378_residues
MTIPQELVQKTVEAIRGLAKEAVKKKNKEVIKIMHVCGTHEHTVTHNGLRSLMPPEVELIAGPGCPVCVTPAAAVDALID
LSLSGVRVYAYGDVYKLPGTKGSLAVAKARGGDVKVVYGFLDAIRDAKQYGKEAVFFGVGFETTVVTVAGPIYDGRVPKN
LKVLSAYLLTAPGLKRAIEAHEATGIPLDGIIAPGHVSSVIGANAWKYLPEEFGFPTVVAGFEAYDYLLAVAEILRQIVR
GEAKLVNEYSRVVRPEGNVTAWRKVMEVFDVVDAYWRGIGVLPESGLAFKEKYKDYDAAAEYGIEIKPTERELPPGCKCA
EINLGIAKPTDCPYFKTRCTPTTPIGPCMVSDEGTCSIWARFGGGGLVEELARLAGIE
>Mature_377_residues
TIPQELVQKTVEAIRGLAKEAVKKKNKEVIKIMHVCGTHEHTVTHNGLRSLMPPEVELIAGPGCPVCVTPAAAVDALIDL
SLSGVRVYAYGDVYKLPGTKGSLAVAKARGGDVKVVYGFLDAIRDAKQYGKEAVFFGVGFETTVVTVAGPIYDGRVPKNL
KVLSAYLLTAPGLKRAIEAHEATGIPLDGIIAPGHVSSVIGANAWKYLPEEFGFPTVVAGFEAYDYLLAVAEILRQIVRG
EAKLVNEYSRVVRPEGNVTAWRKVMEVFDVVDAYWRGIGVLPESGLAFKEKYKDYDAAAEYGIEIKPTERELPPGCKCAE
INLGIAKPTDCPYFKTRCTPTTPIGPCMVSDEGTCSIWARFGGGGLVEELARLAGIE

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=364, Percent_Identity=37.3626373626374, Blast_Score=244, Evalue=9e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40728; Mature: 40596

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPQELVQKTVEAIRGLAKEAVKKKNKEVIKIMHVCGTHEHTVTHNGLRSLMPPEVELI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEE
AGPGCPVCVTPAAAVDALIDLSLSGVRVYAYGDVYKLPGTKGSLAVAKARGGDVKVVYGF
ECCCCCEEECCHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCEEEEECCCCCEEEHHHH
LDAIRDAKQYGKEAVFFGVGFETTVVTVAGPIYDGRVPKNLKVLSAYLLTAPGLKRAIEA
HHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
HEATGIPLDGIIAPGHVSSVIGANAWKYLPEEFGFPTVVAGFEAYDYLLAVAEILRQIVR
HHCCCCCCCCEECCCHHHHHHHCHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GEAKLVNEYSRVVRPEGNVTAWRKVMEVFDVVDAYWRGIGVLPESGLAFKEKYKDYDAAA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHH
EYGIEIKPTERELPPGCKCAEINLGIAKPTDCPYFKTRCTPTTPIGPCMVSDEGTCSIWA
HCCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEE
RFGGGGLVEELARLAGIE
EECCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TIPQELVQKTVEAIRGLAKEAVKKKNKEVIKIMHVCGTHEHTVTHNGLRSLMPPEVELI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEE
AGPGCPVCVTPAAAVDALIDLSLSGVRVYAYGDVYKLPGTKGSLAVAKARGGDVKVVYGF
ECCCCCEEECCHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCEEEEECCCCCEEEHHHH
LDAIRDAKQYGKEAVFFGVGFETTVVTVAGPIYDGRVPKNLKVLSAYLLTAPGLKRAIEA
HHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
HEATGIPLDGIIAPGHVSSVIGANAWKYLPEEFGFPTVVAGFEAYDYLLAVAEILRQIVR
HHCCCCCCCCEECCCHHHHHHHCHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GEAKLVNEYSRVVRPEGNVTAWRKVMEVFDVVDAYWRGIGVLPESGLAFKEKYKDYDAAA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHH
EYGIEIKPTERELPPGCKCAEINLGIAKPTDCPYFKTRCTPTTPIGPCMVSDEGTCSIWA
HCCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEE
RFGGGGLVEELARLAGIE
EECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]