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The map label for this gene is 156937136

Identifier: 156937136

GI number: 156937136

Start: 300240

End: 301523

Strand: Direct

Name: 156937136

Synonym: Igni_0342

Alternate gene names: NA

Gene position: 300240-301523 (Clockwise)

Preceding gene: 156937133

Following gene: 156937142

Centisome position: 23.14

GC content: 58.18

Gene sequence:

>1284_bases
TTGAGGATAACGGAAGAGGCCTTGGAGGTGGTGAAACACTACCCCCTATGCGACCACTGCTTGGGCTCCTTGTTCGCCAG
GCTGGGCAAGGGCTTGGGGAACGAGCACAGGGGAGAAGCCATAAGAAGAGTAATTATCATGGAGTTGGATAGAATGGTCA
GAGAAGGGGAAATAAAAAAGGAGGAGGCAGAAAAGATAATGAGTAACTTCGATTCTGACGAGGTGGAGGAGCTGGCTAAG
AACATGGGCTACTCCGTCCGGAGGAGGAGCTGTTACGTCTGCGGGGGCAAGTGGAGGGAGCTGGTGGAGGAGTGGAGTAA
GAAGGTAGTAGACGCCTTGAAGGAGTACGAGTTCGACACGTTCTTGGTGGGCTGTTCGGACTGCGGGGGAATGGTCGAGA
GGCAGAGGGAGATAATAAGCGCCTTTAGGCTCCCGTACGCCGAGAGCGTGAAGAACTCGCTGAAGAGGGAAGTGGGCAAG
AGGGTCAAGGAGCTCCTCGGAAAGGAGCCGGACTTCGAGGACCCGCACGTGGTCGCAATAATGAACTTGAGGGAGGACAA
GGTAGACTTACAAATAAAGCCCGTGTTTATATACGGCATATACAAGAAGAAGGCGAGGAACGTCTCCCAGAGCGAGTGGA
AGTACCCGTATTCGGTGGAGAGGGCGGTTAGGAAGGCCCTATCCCCCTTCGGAGGGGAGGTGGTCCTCCACGCCTCCGGG
AGGGAGGACGTGGACGTGAGGGCCTTGGGGACGGGCAGACCCTTCGTGGCGGAGGTGAAGAGGCCTAAGAGGAGGAGGCT
CCCGGTAGAGGGCTCGGAGTACGAGGACGAGCTGGTGTGGCTCAGGTTCGAGCGCTACGTGAACCGCGACTGGGTACAGA
GGGTGAAGGGCGACGAGTCCAAGAAGGAGAAGGTCTACTTGGCCTTGGTTTACGTGCCCGAAGGCGTGGACGAGGGGGAC
TTGAGGGCCCTAGAGGAGTTCTTCGAGGACGTGACGATAAAGCAGAGGACGCCCAAGAGGGTGCTCCACAGGAGGGCGGA
CGTGGTGAGGGAGAGGAAGGTGTACTGGGTCAAGGCAAGGAAGCTCAACGACAAGTCCTTCGAGGCCCTCATAAAGGCCC
AAGGGGGCCTCTACATAAAGGAGCTGGTGAGCGGGGACGAGGGGAGGACCGAACCCTCCTTCAGCTCCTTCTTAGGGAAG
GAAGCGACCTGCGCGAGCTTGGACGTTGTCTGGGTCTCCTTGCCACAGGCCGAGCTTCGAGGCGGAGGAGAGGAGCGCGG
ATAG

Upstream 100 bases:

>100_bases
CCTTCACCGTCCCTACCTCTAGCGGGCCTTGTGTAAATGTGGGTATATATCCACTGCTTCAGCGGCTATAACCGCTCCGA
CGGAGGGCGAGGGGGAGCGC

Downstream 100 bases:

>100_bases
CACCCTTTCGTCCCTCCCGAAGAACAGGTTGCCCACCACGCTCACCTCGTCCGTGGGGAAGGACTCGTAAACCTCCGGCA
CGGGGACGCCGGCCCTCTTG

Product: pseudouridylate synthase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MRITEEALEVVKHYPLCDHCLGSLFARLGKGLGNEHRGEAIRRVIIMELDRMVREGEIKKEEAEKIMSNFDSDEVEELAK
NMGYSVRRRSCYVCGGKWRELVEEWSKKVVDALKEYEFDTFLVGCSDCGGMVERQREIISAFRLPYAESVKNSLKREVGK
RVKELLGKEPDFEDPHVVAIMNLREDKVDLQIKPVFIYGIYKKKARNVSQSEWKYPYSVERAVRKALSPFGGEVVLHASG
REDVDVRALGTGRPFVAEVKRPKRRRLPVEGSEYEDELVWLRFERYVNRDWVQRVKGDESKKEKVYLALVYVPEGVDEGD
LRALEEFFEDVTIKQRTPKRVLHRRADVVRERKVYWVKARKLNDKSFEALIKAQGGLYIKELVSGDEGRTEPSFSSFLGK
EATCASLDVVWVSLPQAELRGGGEERG

Sequences:

>Translated_427_residues
MRITEEALEVVKHYPLCDHCLGSLFARLGKGLGNEHRGEAIRRVIIMELDRMVREGEIKKEEAEKIMSNFDSDEVEELAK
NMGYSVRRRSCYVCGGKWRELVEEWSKKVVDALKEYEFDTFLVGCSDCGGMVERQREIISAFRLPYAESVKNSLKREVGK
RVKELLGKEPDFEDPHVVAIMNLREDKVDLQIKPVFIYGIYKKKARNVSQSEWKYPYSVERAVRKALSPFGGEVVLHASG
REDVDVRALGTGRPFVAEVKRPKRRRLPVEGSEYEDELVWLRFERYVNRDWVQRVKGDESKKEKVYLALVYVPEGVDEGD
LRALEEFFEDVTIKQRTPKRVLHRRADVVRERKVYWVKARKLNDKSFEALIKAQGGLYIKELVSGDEGRTEPSFSSFLGK
EATCASLDVVWVSLPQAELRGGGEERG
>Mature_427_residues
MRITEEALEVVKHYPLCDHCLGSLFARLGKGLGNEHRGEAIRRVIIMELDRMVREGEIKKEEAEKIMSNFDSDEVEELAK
NMGYSVRRRSCYVCGGKWRELVEEWSKKVVDALKEYEFDTFLVGCSDCGGMVERQREIISAFRLPYAESVKNSLKREVGK
RVKELLGKEPDFEDPHVVAIMNLREDKVDLQIKPVFIYGIYKKKARNVSQSEWKYPYSVERAVRKALSPFGGEVVLHASG
REDVDVRALGTGRPFVAEVKRPKRRRLPVEGSEYEDELVWLRFERYVNRDWVQRVKGDESKKEKVYLALVYVPEGVDEGD
LRALEEFFEDVTIKQRTPKRVLHRRADVVRERKVYWVKARKLNDKSFEALIKAQGGLYIKELVSGDEGRTEPSFSSFLGK
EATCASLDVVWVSLPQAELRGGGEERG

Specific function: Unknown

COG id: COG1258

COG function: function code J; Predicted pseudouridylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

Organism=Homo sapiens, GI207113130, Length=230, Percent_Identity=35.6521739130435, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17537241, Length=305, Percent_Identity=33.4426229508197, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19920442, Length=251, Percent_Identity=35.4581673306773, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005912
- InterPro:   IPR020103
- InterPro:   IPR004114 [H]

Pfam domain/function: PF02926 THUMP [H]

EC number: NA

Molecular weight: Translated: 49219; Mature: 49219

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS51165 THUMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITEEALEVVKHYPLCDHCLGSLFARLGKGLGNEHRGEAIRRVIIMELDRMVREGEIKK
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EEAEKIMSNFDSDEVEELAKNMGYSVRRRSCYVCGGKWRELVEEWSKKVVDALKEYEFDT
HHHHHHHHCCCHHHHHHHHHHCCCHHHHCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCE
FLVGCSDCGGMVERQREIISAFRLPYAESVKNSLKREVGKRVKELLGKEPDFEDPHVVAI
EEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
MNLREDKVDLQIKPVFIYGIYKKKARNVSQSEWKYPYSVERAVRKALSPFGGEVVLHASG
EECCCCCCCEEEEEEEEEEEHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCEEEEEECC
REDVDVRALGTGRPFVAEVKRPKRRRLPVEGSEYEDELVWLRFERYVNRDWVQRVKGDES
CCCCEEEEECCCCCHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCC
KKEKVYLALVYVPEGVDEGDLRALEEFFEDVTIKQRTPKRVLHRRADVVRERKVYWVKAR
CCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEE
KLNDKSFEALIKAQGGLYIKELVSGDEGRTEPSFSSFLGKEATCASLDVVWVSLPQAELR
CCCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCEEEEEEEECCHHHHC
GGGEERG
CCCCCCC
>Mature Secondary Structure
MRITEEALEVVKHYPLCDHCLGSLFARLGKGLGNEHRGEAIRRVIIMELDRMVREGEIKK
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EEAEKIMSNFDSDEVEELAKNMGYSVRRRSCYVCGGKWRELVEEWSKKVVDALKEYEFDT
HHHHHHHHCCCHHHHHHHHHHCCCHHHHCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCE
FLVGCSDCGGMVERQREIISAFRLPYAESVKNSLKREVGKRVKELLGKEPDFEDPHVVAI
EEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
MNLREDKVDLQIKPVFIYGIYKKKARNVSQSEWKYPYSVERAVRKALSPFGGEVVLHASG
EECCCCCCCEEEEEEEEEEEHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCEEEEEECC
REDVDVRALGTGRPFVAEVKRPKRRRLPVEGSEYEDELVWLRFERYVNRDWVQRVKGDES
CCCCEEEEECCCCCHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCC
KKEKVYLALVYVPEGVDEGDLRALEEFFEDVTIKQRTPKRVLHRRADVVRERKVYWVKAR
CCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEE
KLNDKSFEALIKAQGGLYIKELVSGDEGRTEPSFSSFLGKEATCASLDVVWVSLPQAELR
CCCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCEEEEEEEECCHHHHC
GGGEERG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]