| Definition | Ignicoccus hospitalis KIN4/I chromosome, complete genome. |
|---|---|
| Accession | NC_009776 |
| Length | 1,297,538 |
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The map label for this gene is acsA [H]
Identifier: 156937052
GI number: 156937052
Start: 222448
End: 223149
Strand: Direct
Name: acsA [H]
Synonym: Igni_0257
Alternate gene names: 156937052
Gene position: 222448-223149 (Clockwise)
Preceding gene: 156937051
Following gene: 156937056
Centisome position: 17.14
GC content: 62.11
Gene sequence:
>702_bases ATGATAAGCCCCGCCCCCGGGATAGAGCTGGTCCCCCTGAAGCCGGGGAGCGCCACCTTCCCGTTGCCCGGCGTGGACGC CGAGGTGGTGGACGACAACGGCAACCCCGCGCCTCCCGGAACTAAGGGCTACTTGGTCATAAGGAAGCCGTGGCCCGGCA TGTTGCACGGTATCTGGGGAGACCCGGAGAGGTACGTGAGGACCTACTGGAGCAAGTTCCCCGGGTGGTACTTCACCGGC GACTACGCGATGAAGGACGAGGACGGCTACTTCTGGATATTGGGTAGGGCGGACGACGTGATCAAGGTCGCCGGCCACAG GCTGGGCACCTTGGAGATAGAGAGCGCCTTCGTCGCCCACCCCGCGGTGGCCGAGGCGGCGGTGGTGGGCAAGCCCCACC CGGTCAAGGGAGAGGGCATAGTGGCCTTCGTAGTGTTGAAGGAGGGTTACCAGCCCAGCGACGAACTGAGGGATGAGCTG AGGAAGTGGATAAGGGAGACCATAGGCCCCGTCGCCACTCCGGACGAGATACACTTCGTTACCAAGTTGCCTAAGACTAG GAGCGGAAAGATAATGAGGAGGGTGCTTAGGGCGGTGATAAGCGGCCAGCCCTTGGGAGACTTGAGCACCTTGGAGGACG AGGCGTCCGTGGAGGAAGTGAAGAGGGCGGTAGAGGAGTTGAGGAGAGACTTAGGAATGTGA
Upstream 100 bases:
>100_bases ACGTCGGCAAGGGCAAGTGTCCCATAGTAGACACTTGGTGGCAGACGGAGACCGGGCACACATAGTAGACACTTGGTGGC AGACGGAGACCGGGCACATA
Downstream 100 bases:
>100_bases CCTCGAGGAACCCTTTCTTTCACTTTAAATAAAAACTTACCAACCCAAGACCCCGCCTATGTCCGCGGTCTCCTCGGCCT CGGTCGCGCACTGGACCGCT
Product: Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase-like protein
Products: NA
Alternate protein names: Acetate--CoA ligase; Acyl-activating enzyme [H]
Number of amino acids: Translated: 233; Mature: 233
Protein sequence:
>233_residues MISPAPGIELVPLKPGSATFPLPGVDAEVVDDNGNPAPPGTKGYLVIRKPWPGMLHGIWGDPERYVRTYWSKFPGWYFTG DYAMKDEDGYFWILGRADDVIKVAGHRLGTLEIESAFVAHPAVAEAAVVGKPHPVKGEGIVAFVVLKEGYQPSDELRDEL RKWIRETIGPVATPDEIHFVTKLPKTRSGKIMRRVLRAVISGQPLGDLSTLEDEASVEEVKRAVEELRRDLGM
Sequences:
>Translated_233_residues MISPAPGIELVPLKPGSATFPLPGVDAEVVDDNGNPAPPGTKGYLVIRKPWPGMLHGIWGDPERYVRTYWSKFPGWYFTG DYAMKDEDGYFWILGRADDVIKVAGHRLGTLEIESAFVAHPAVAEAAVVGKPHPVKGEGIVAFVVLKEGYQPSDELRDEL RKWIRETIGPVATPDEIHFVTKLPKTRSGKIMRRVLRAVISGQPLGDLSTLEDEASVEEVKRAVEELRRDLGM >Mature_233_residues MISPAPGIELVPLKPGSATFPLPGVDAEVVDDNGNPAPPGTKGYLVIRKPWPGMLHGIWGDPERYVRTYWSKFPGWYFTG DYAMKDEDGYFWILGRADDVIKVAGHRLGTLEIESAFVAHPAVAEAAVVGKPHPVKGEGIVAFVVLKEGYQPSDELRDEL RKWIRETIGPVATPDEIHFVTKLPKTRSGKIMRRVLRAVISGQPLGDLSTLEDEASVEEVKRAVEELRRDLGM
Specific function: Enables The Cell To Use Acetate During Aerobic Growth To Generate Energy Via The Tca Cycle, And Biosynthetic Compounds Via The Glyoxylate Shunt. Acetylates Chey, The Response Regulator Involved In Flagellar Movement And Chemotaxis. [C]
COG id: COG0365
COG function: function code I; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]
Homologues:
Organism=Homo sapiens, GI8923896, Length=221, Percent_Identity=52.0361990950226, Blast_Score=228, Evalue=3e-60, Organism=Homo sapiens, GI253970489, Length=221, Percent_Identity=52.0361990950226, Blast_Score=228, Evalue=3e-60, Organism=Homo sapiens, GI28416953, Length=231, Percent_Identity=44.1558441558442, Blast_Score=197, Evalue=6e-51, Organism=Homo sapiens, GI13375727, Length=214, Percent_Identity=39.2523364485981, Blast_Score=159, Evalue=2e-39, Organism=Homo sapiens, GI42544132, Length=193, Percent_Identity=40.9326424870466, Blast_Score=144, Evalue=7e-35, Organism=Homo sapiens, GI115511026, Length=196, Percent_Identity=42.8571428571429, Blast_Score=143, Evalue=1e-34, Organism=Homo sapiens, GI38505220, Length=192, Percent_Identity=40.625, Blast_Score=141, Evalue=6e-34, Organism=Homo sapiens, GI157311624, Length=192, Percent_Identity=40.625, Blast_Score=139, Evalue=2e-33, Organism=Homo sapiens, GI157311622, Length=192, Percent_Identity=40.625, Blast_Score=139, Evalue=2e-33, Organism=Homo sapiens, GI58082049, Length=192, Percent_Identity=40.625, Blast_Score=139, Evalue=3e-33, Organism=Homo sapiens, GI122937307, Length=191, Percent_Identity=42.4083769633508, Blast_Score=139, Evalue=3e-33, Organism=Homo sapiens, GI187761345, Length=203, Percent_Identity=32.512315270936, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI187761343, Length=203, Percent_Identity=32.512315270936, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI156151445, Length=177, Percent_Identity=35.0282485875706, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI31982927, Length=198, Percent_Identity=26.2626262626263, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI1790505, Length=222, Percent_Identity=55.8558558558559, Blast_Score=244, Evalue=3e-66, Organism=Escherichia coli, GI1786529, Length=238, Percent_Identity=42.436974789916, Blast_Score=166, Evalue=2e-42, Organism=Escherichia coli, GI1788107, Length=182, Percent_Identity=36.2637362637363, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI145693145, Length=178, Percent_Identity=33.7078651685393, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI221142682, Length=173, Percent_Identity=30.0578034682081, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1786810, Length=170, Percent_Identity=32.3529411764706, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1789201, Length=193, Percent_Identity=31.6062176165803, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71983001, Length=222, Percent_Identity=47.7477477477478, Blast_Score=190, Evalue=4e-49, Organism=Caenorhabditis elegans, GI71982997, Length=222, Percent_Identity=47.7477477477478, Blast_Score=190, Evalue=5e-49, Organism=Caenorhabditis elegans, GI17559526, Length=176, Percent_Identity=30.6818181818182, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17558820, Length=140, Percent_Identity=32.1428571428571, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI32563687, Length=145, Percent_Identity=30.3448275862069, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17560140, Length=136, Percent_Identity=33.0882352941176, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538037, Length=156, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17557194, Length=152, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71985884, Length=182, Percent_Identity=30.2197802197802, Blast_Score=70, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17531443, Length=182, Percent_Identity=29.1208791208791, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17569507, Length=224, Percent_Identity=23.2142857142857, Blast_Score=68, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71994690, Length=175, Percent_Identity=26.2857142857143, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71994694, Length=175, Percent_Identity=26.2857142857143, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI71994703, Length=175, Percent_Identity=26.2857142857143, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6319264, Length=236, Percent_Identity=45.3389830508475, Blast_Score=196, Evalue=2e-51, Organism=Saccharomyces cerevisiae, GI6323182, Length=242, Percent_Identity=45.8677685950413, Blast_Score=196, Evalue=3e-51, Organism=Saccharomyces cerevisiae, GI6319699, Length=183, Percent_Identity=31.6939890710383, Blast_Score=97, Evalue=3e-21, Organism=Drosophila melanogaster, GI24667955, Length=228, Percent_Identity=49.1228070175439, Blast_Score=216, Evalue=1e-56, Organism=Drosophila melanogaster, GI62472339, Length=221, Percent_Identity=49.3212669683258, Blast_Score=216, Evalue=1e-56, Organism=Drosophila melanogaster, GI24667959, Length=228, Percent_Identity=49.1228070175439, Blast_Score=216, Evalue=1e-56, Organism=Drosophila melanogaster, GI21355225, Length=213, Percent_Identity=34.7417840375587, Blast_Score=135, Evalue=3e-32, Organism=Drosophila melanogaster, GI18859661, Length=194, Percent_Identity=34.020618556701, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI21355181, Length=193, Percent_Identity=31.6062176165803, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24581924, Length=169, Percent_Identity=32.5443786982249, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI21358303, Length=154, Percent_Identity=32.4675324675325, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI21356947, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648260, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648257, Length=189, Percent_Identity=27.5132275132275, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI24653035, Length=187, Percent_Identity=28.3422459893048, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011904 - InterPro: IPR020845 - InterPro: IPR000873 [H]
Pfam domain/function: PF00501 AMP-binding [H]
EC number: =6.2.1.1 [H]
Molecular weight: Translated: 25722; Mature: 25722
Theoretical pI: Translated: 5.71; Mature: 5.71
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MISPAPGIELVPLKPGSATFPLPGVDAEVVDDNGNPAPPGTKGYLVIRKPWPGMLHGIWG CCCCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCHHCCCCC DPERYVRTYWSKFPGWYFTGDYAMKDEDGYFWILGRADDVIKVAGHRLGTLEIESAFVAH CHHHHHHHHHHHCCCCEEECCEEEECCCCEEEEEECCCCHHHHHCCCCCEEEECCHHHCC PAVAEAAVVGKPHPVKGEGIVAFVVLKEGYQPSDELRDELRKWIRETIGPVATPDEIHFV CHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE TKLPKTRSGKIMRRVLRAVISGQPLGDLSTLEDEASVEEVKRAVEELRRDLGM ECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MISPAPGIELVPLKPGSATFPLPGVDAEVVDDNGNPAPPGTKGYLVIRKPWPGMLHGIWG CCCCCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCHHCCCCC DPERYVRTYWSKFPGWYFTGDYAMKDEDGYFWILGRADDVIKVAGHRLGTLEIESAFVAH CHHHHHHHHHHHCCCCEEECCEEEECCCCEEEEEECCCCHHHHHCCCCCEEEECCHHHCC PAVAEAAVVGKPHPVKGEGIVAFVVLKEGYQPSDELRDELRKWIRETIGPVATPDEIHFV CHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE TKLPKTRSGKIMRRVLRAVISGQPLGDLSTLEDEASVEEVKRAVEELRRDLGM ECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11792869 [H]