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The map label for this gene is 156936885

Identifier: 156936885

GI number: 156936885

Start: 85828

End: 86532

Strand: Direct

Name: 156936885

Synonym: Igni_0090

Alternate gene names: NA

Gene position: 85828-86532 (Clockwise)

Preceding gene: 156936884

Following gene: 156936886

Centisome position: 6.61

GC content: 57.73

Gene sequence:

>705_bases
GTGCTCACTCTGAGCCCCCACGGACCTCCCCCCTTCAAGGACCTCGAAGTGACCAACGTCCCGGCGCTAGAGCTGGTGGA
CGTCGCGGACGCCTCCCAAATCAAGGAAGCCATAAAGGAGGGGGAGGCAGTAGTCTTCACTTCCAAGACCGGCGTGAGGT
TGGTGTTCGAAAAGCTCGGGGACGAGGCCCTCGAGTTGCTCAAGGGGAAGGACGTGGTGGCAATAGGGCCCAAGACGGCG
GCCGAGCTCGAGGCGAGGGGCTTGAGCCCCATAGTGCCGGAGGAGTACCACTCCGGCGCGCTGGCAAAGCTCTTGAAGCG
TTACAACAAGGTAGTGGCCCTGAGGTCCGACAAGGCGTCAAAGACTTTGAAGGATGAGTTAGGAGACAAGCTCATCGAGG
TGGTTATTTATAAAACCTTGAGGAGGCCCTCTCCAAAGATAGTGGAGGCGGCTAGGGAGGCCGACGCAGTTGCCGTGAGC
AGCGCCGAGGTCGCCCGGGCCTTAATAGAGTCCTTTCAGAAGTACTCTAGTATTGACGAACTTAAGAAGTTGAAAATAGC
CGTAATAGGGCCCGAGGCAGCAAAGCCGTTGAAGGAGTTGGGCTTGAACTTCGTGGTCGCCCCGGAAGCCACTTTTGAAG
GGTTGGAGGAGGCAGTTAAGAGAATAATACGGGGAGGACCGGGAGAAAGCCCCGAGGAGCGCTAA

Upstream 100 bases:

>100_bases
AGGTAATGGTCCGTAACGGGGTAAAGCCGCCGGCGGTTTTGGTGTTCGGAGAGGTGGTCGAGTGGGCTTGCAAGGCGGGC
ACGGTAAGGGACGTGGTAGA

Downstream 100 bases:

>100_bases
CGAAAAACGGGGAACGCCGGGTGAGGGTGAAGTCCTTCGAGGGCTTCCCGGTGGAGGCGGAAGGGGTCGAGGACCCCGAG
ATGGTGGCGGCAGTGTTGGG

Product: uroporphyrinogen III synthase HEM4

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen-III Synthase

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLTLSPHGPPPFKDLEVTNVPALELVDVADASQIKEAIKEGEAVVFTSKTGVRLVFEKLGDEALELLKGKDVVAIGPKTA
AELEARGLSPIVPEEYHSGALAKLLKRYNKVVALRSDKASKTLKDELGDKLIEVVIYKTLRRPSPKIVEAAREADAVAVS
SAEVARALIESFQKYSSIDELKKLKIAVIGPEAAKPLKELGLNFVVAPEATFEGLEEAVKRIIRGGPGESPEER

Sequences:

>Translated_234_residues
MLTLSPHGPPPFKDLEVTNVPALELVDVADASQIKEAIKEGEAVVFTSKTGVRLVFEKLGDEALELLKGKDVVAIGPKTA
AELEARGLSPIVPEEYHSGALAKLLKRYNKVVALRSDKASKTLKDELGDKLIEVVIYKTLRRPSPKIVEAAREADAVAVS
SAEVARALIESFQKYSSIDELKKLKIAVIGPEAAKPLKELGLNFVVAPEATFEGLEEAVKRIIRGGPGESPEER
>Mature_234_residues
MLTLSPHGPPPFKDLEVTNVPALELVDVADASQIKEAIKEGEAVVFTSKTGVRLVFEKLGDEALELLKGKDVVAIGPKTA
AELEARGLSPIVPEEYHSGALAKLLKRYNKVVALRSDKASKTLKDELGDKLIEVVIYKTLRRPSPKIVEAAREADAVAVS
SAEVARALIESFQKYSSIDELKKLKIAVIGPEAAKPLKELGLNFVVAPEATFEGLEEAVKRIIRGGPGESPEER

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 25256; Mature: 25256

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLSPHGPPPFKDLEVTNVPALELVDVADASQIKEAIKEGEAVVFTSKTGVRLVFEKLG
CCCCCCCCCCCCCCCEECCCCHHHHHHHCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHC
DEALELLKGKDVVAIGPKTAAELEARGLSPIVPEEYHSGALAKLLKRYNKVVALRSDKAS
HHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHEEECCCHHH
KTLKDELGDKLIEVVIYKTLRRPSPKIVEAAREADAVAVSSAEVARALIESFQKYSSIDE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LKKLKIAVIGPEAAKPLKELGLNFVVAPEATFEGLEEAVKRIIRGGPGESPEER
HHHHEEEEECCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLTLSPHGPPPFKDLEVTNVPALELVDVADASQIKEAIKEGEAVVFTSKTGVRLVFEKLG
CCCCCCCCCCCCCCCEECCCCHHHHHHHCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHC
DEALELLKGKDVVAIGPKTAAELEARGLSPIVPEEYHSGALAKLLKRYNKVVALRSDKAS
HHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHEEECCCHHH
KTLKDELGDKLIEVVIYKTLRRPSPKIVEAAREADAVAVSSAEVARALIESFQKYSSIDE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LKKLKIAVIGPEAAKPLKELGLNFVVAPEATFEGLEEAVKRIIRGGPGESPEER
HHHHEEEEECCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA