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The map label for this gene is 156936865

Identifier: 156936865

GI number: 156936865

Start: 66725

End: 68026

Strand: Direct

Name: 156936865

Synonym: Igni_0070

Alternate gene names: NA

Gene position: 66725-68026 (Clockwise)

Preceding gene: 156936863

Following gene: 156936866

Centisome position: 5.14

GC content: 58.29

Gene sequence:

>1302_bases
ATGACGAAAAAGTACTTGGTCCAGCACGCTCTGGGGGCGTTCCTGCTCGACCCCCAAGGGAACGTAGAGAGGTACGAGTT
GAACACCAAGGACGTGGACGAAGCTGCGGAACAAGCGCTGGTGATGGAAGGTTGGGTCAGAGGGATGAGGGAAGGCGAGG
AGAAGCGCGCCGGCTTGGCGGCCCCGGCGAGGAAGCTCCTAGAGAATTTAAAGAACGAGAACTTCGAGGGGGTCCTAGTA
TTCGAAACGGACTCCGAGTCCAGGGAGGCCGCTAAGCTGGGCTTCGAGGTAGCCGTAGAGCCCGCCAACGAGCCGGCCCG
CGCGCTCCGATCCCAAGTGGCCAGCTTAGCGGTCAAGTACGGCTTTGTTGACAGCGAGAAGGAGTTTTACGAGTGGTTGA
GGAGGGTCGACATAGAGGTCGTCAGGAGGAAGCTGAGGAGCGTCGCGCAGAAGAGGGACTTGCTGGCAGCCCAAGCGGTT
AGGAGCATAGACGACATCGACAAGGTCGTGAACTTAATGGTGGCTAGGCTGAGGGAGTGGTACTCCCTACACTTCCCAGA
GCTGGACAAGCTTGTCAAGGACCACGAAGCCTTCGTAAAAATAGTAGCCGAATTAGGCGGGAGAGACAACATTACCAAGG
AGAAGCTGCTCGAGCTGGGCTTCAGCGAGGCCTTGGCTGAGAAGATAGCCGAAGCCGCTAAGAAGAGTACGGGCGCCGAC
CTAACCGAGACAGACATAGAGCAGTTGCAGAAGTTGGCGTCAATAATAATGAGCTTGTACAACTTGAGGAGGGACTTGGT
CGACTACATAAGCTACATAATGAAAGAGGTGGCGCCCAACGTGACCGCCCTAGTGGGTCCGGTGCTGGGCGCGAGGCTCA
TATCGCTCGCCGGCTCCTTGGAGAACCTCGCGAAGATGCCAGCCTCCACGATACAAGTGCTGGGCGCGGAGAAGGCGTTA
TTCAGAGCTCTGAGGACCGGGGGCAAGCCCCCCAAGCACGGCGTGATCTTCCAGTACCCGGACATACATAGGAGTCCGAA
GTGGCAGAGGGGTAAGATAGCCAGGGCGCTCGCTGCCAAACTGGCGATAGCCGCTAGGACGGACTACTTCACGGGCAGGA
ACATAGGCGAAAGGCTGAGGGAAGAGCTGAGGGCGAGGATAGAAGAAATAAAGAGGGTCTATGCCAAGCCGCCCAAGAAG
ACCGAGGAAGAGAAGAAGGCCCCTCCGGCCAAGAGGGCCAAGAAGAGGCCCCCCAGGAAGGGGGGCAAGAAGGGCCCCAG
GAAGGGCGGCAGGAGGAAGTAG

Upstream 100 bases:

>100_bases
GTCCCGGGATAGGCAGTCATCGTTCCTTAAGGGGCGGGACGTCCTCATCGGCGGGAGCCGTTTTTAATTCCCGGACAAGC
CCGCTTTAGGGACTGAAAGA

Downstream 100 bases:

>100_bases
CCCCGTTGCCTCGGAGGCTGGAGGACTGGAGGGACGCCCGAGCGCCCTTGTTTTGCCACGTGTCTGAGGTGATCGACGAG
TTCGGGGAGGTGGTTCACTG

Product: C/D box methylation guide ribonucleoprotein complex aNOP56 subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTKKYLVQHALGAFLLDPQGNVERYELNTKDVDEAAEQALVMEGWVRGMREGEEKRAGLAAPARKLLENLKNENFEGVLV
FETDSESREAAKLGFEVAVEPANEPARALRSQVASLAVKYGFVDSEKEFYEWLRRVDIEVVRRKLRSVAQKRDLLAAQAV
RSIDDIDKVVNLMVARLREWYSLHFPELDKLVKDHEAFVKIVAELGGRDNITKEKLLELGFSEALAEKIAEAAKKSTGAD
LTETDIEQLQKLASIIMSLYNLRRDLVDYISYIMKEVAPNVTALVGPVLGARLISLAGSLENLAKMPASTIQVLGAEKAL
FRALRTGGKPPKHGVIFQYPDIHRSPKWQRGKIARALAAKLAIAARTDYFTGRNIGERLREELRARIEEIKRVYAKPPKK
TEEEKKAPPAKRAKKRPPRKGGKKGPRKGGRRK

Sequences:

>Translated_433_residues
MTKKYLVQHALGAFLLDPQGNVERYELNTKDVDEAAEQALVMEGWVRGMREGEEKRAGLAAPARKLLENLKNENFEGVLV
FETDSESREAAKLGFEVAVEPANEPARALRSQVASLAVKYGFVDSEKEFYEWLRRVDIEVVRRKLRSVAQKRDLLAAQAV
RSIDDIDKVVNLMVARLREWYSLHFPELDKLVKDHEAFVKIVAELGGRDNITKEKLLELGFSEALAEKIAEAAKKSTGAD
LTETDIEQLQKLASIIMSLYNLRRDLVDYISYIMKEVAPNVTALVGPVLGARLISLAGSLENLAKMPASTIQVLGAEKAL
FRALRTGGKPPKHGVIFQYPDIHRSPKWQRGKIARALAAKLAIAARTDYFTGRNIGERLREELRARIEEIKRVYAKPPKK
TEEEKKAPPAKRAKKRPPRKGGKKGPRKGGRRK
>Mature_432_residues
TKKYLVQHALGAFLLDPQGNVERYELNTKDVDEAAEQALVMEGWVRGMREGEEKRAGLAAPARKLLENLKNENFEGVLVF
ETDSESREAAKLGFEVAVEPANEPARALRSQVASLAVKYGFVDSEKEFYEWLRRVDIEVVRRKLRSVAQKRDLLAAQAVR
SIDDIDKVVNLMVARLREWYSLHFPELDKLVKDHEAFVKIVAELGGRDNITKEKLLELGFSEALAEKIAEAAKKSTGADL
TETDIEQLQKLASIIMSLYNLRRDLVDYISYIMKEVAPNVTALVGPVLGARLISLAGSLENLAKMPASTIQVLGAEKALF
RALRTGGKPPKHGVIFQYPDIHRSPKWQRGKIARALAAKLAIAARTDYFTGRNIGERLREELRARIEEIKRVYAKPPKKT
EEEKKAPPAKRAKKRPPRKGGKKGPRKGGRRK

Specific function: Unknown

COG id: COG1498

COG function: function code J; Protein implicated in ribosomal biogenesis, Nop56p homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Nop domain [H]

Homologues:

Organism=Homo sapiens, GI32483374, Length=252, Percent_Identity=40.8730158730159, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI7706254, Length=298, Percent_Identity=38.255033557047, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI221136939, Length=257, Percent_Identity=27.6264591439689, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17509449, Length=291, Percent_Identity=39.8625429553265, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17562296, Length=256, Percent_Identity=39.453125, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17510923, Length=361, Percent_Identity=28.808864265928, Blast_Score=112, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323226, Length=268, Percent_Identity=39.5522388059701, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6324886, Length=271, Percent_Identity=40.590405904059, Blast_Score=193, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6321528, Length=274, Percent_Identity=26.2773722627737, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17137636, Length=229, Percent_Identity=44.9781659388646, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI28572126, Length=253, Percent_Identity=41.1067193675889, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21357435, Length=273, Percent_Identity=27.8388278388278, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012976
- InterPro:   IPR002687 [H]

Pfam domain/function: PF01798 Nop; PF08060 NOSIC [H]

EC number: NA

Molecular weight: Translated: 48637; Mature: 48506

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKYLVQHALGAFLLDPQGNVERYELNTKDVDEAAEQALVMEGWVRGMREGEEKRAGLA
CCHHHHHHHHHHHEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCHH
APARKLLENLKNENFEGVLVFETDSESREAAKLGFEVAVEPANEPARALRSQVASLAVKY
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCHHEEECCCCCHHHHHHHHHHHHHHHH
GFVDSEKEFYEWLRRVDIEVVRRKLRSVAQKRDLLAAQAVRSIDDIDKVVNLMVARLREW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSLHFPELDKLVKDHEAFVKIVAELGGRDNITKEKLLELGFSEALAEKIAEAAKKSTGAD
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCC
LTETDIEQLQKLASIIMSLYNLRRDLVDYISYIMKEVAPNVTALVGPVLGARLISLAGSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ENLAKMPASTIQVLGAEKALFRALRTGGKPPKHGVIFQYPDIHRSPKWQRGKIARALAAK
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
LAIAARTDYFTGRNIGERLREELRARIEEIKRVYAKPPKKTEEEKKAPPAKRAKKRPPRK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHCCCCCC
GGKKGPRKGGRRK
CCCCCCCCCCCCC
>Mature Secondary Structure 
TKKYLVQHALGAFLLDPQGNVERYELNTKDVDEAAEQALVMEGWVRGMREGEEKRAGLA
CHHHHHHHHHHHEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCHH
APARKLLENLKNENFEGVLVFETDSESREAAKLGFEVAVEPANEPARALRSQVASLAVKY
HHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCHHEEECCCCCHHHHHHHHHHHHHHHH
GFVDSEKEFYEWLRRVDIEVVRRKLRSVAQKRDLLAAQAVRSIDDIDKVVNLMVARLREW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSLHFPELDKLVKDHEAFVKIVAELGGRDNITKEKLLELGFSEALAEKIAEAAKKSTGAD
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCC
LTETDIEQLQKLASIIMSLYNLRRDLVDYISYIMKEVAPNVTALVGPVLGARLISLAGSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ENLAKMPASTIQVLGAEKALFRALRTGGKPPKHGVIFQYPDIHRSPKWQRGKIARALAAK
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
LAIAARTDYFTGRNIGERLREELRARIEEIKRVYAKPPKKTEEEKKAPPAKRAKKRPPRK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHCCCCCC
GGKKGPRKGGRRK
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]