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The map label for this gene is yebU [C]

Identifier: 156936862

GI number: 156936862

Start: 64061

End: 65041

Strand: Reverse

Name: yebU [C]

Synonym: Igni_0067

Alternate gene names: 156936862

Gene position: 65041-64061 (Counterclockwise)

Preceding gene: 156936864

Following gene: 156936861

Centisome position: 5.01

GC content: 55.96

Gene sequence:

>981_bases
TTGAAACACCAAGAGATATTGAAGAAACTGAAGGATCTGAAAATAACAAAAGAGGACAAGCTCTTAGCGAGGAAGTACGG
TTACCTCCCCTACATGGTCAGAAGGTACAGAGAGATGCTCGGCGACCCCCTCCCCTTGCTCGAGGCCTTCGAGGTTCCCC
CGAAGCCGACCATAAGGTGCAACTTCTTGAAAGTCGGCTGTGGGAAACTGAAGGAGAGGTTGGAAAGCAGAGGGTTCGTC
TTGAAGCAAGTCCTCTGGTGCCCCCACGCGTACGAGGTTCTAAGAGAACCTTTCTCCTTGTCCTCGACGCCCGAGCACTT
GGACGGCTGGTTCTACATCCAAGACAAGGCCTCGACCTTACCTCCTTTGGTCTTAGGCCCAAAACCCGGCGAGACCGTCG
CGGACCTAGCCTCGGCCCCCGGAGGGAAGGCCACGCACTTGGCCCAGCTCATGGGAAACAGCGGGAGACTGATACTAATA
GAGAGGAGGAGGGACCGAGCTAAGGCGCTGATGAGCAACTTAGAAAGGATGGAGATACTCAACGCAAATGTGATAATAGA
CGACGCCTACAACGCGTCCAAGTACGGCCCCTTCGACAAGGCCTTACTAGACGCGCCGTGCACCGGAGAGGGCGTGATAG
CGCGCGACCCCTCTAGGAAGAGGTCCCGGAGGCCCGAGGACTTGGCGCTCATGCACAAGGTACAAGCGATGCTCCTCAAT
AGGGCTTTGGACTCATTAAAACCGGGAGGGGAGCTGGTCTACTCCACTTGCTCCATAGCCCCGGAGGAAAACGAACTGGT
TATCGAAACTATCCTCAAAACGAGGGACGATGTCGAAGTATTGGATGGGGGAGAGGCCGGCTCGCCCGGGATAGAGGAAT
ACTTGGGGTGGGAGTTCCCCTTCGCCTACAAGTGCAGACGGCTGTGGCCGCACGTACACGGCTCCGAAGGCTTCTTCGTC
TGCAAGCTGAGAAAGCTTTGA

Upstream 100 bases:

>100_bases
GGTCTATTACTGTCCCGCCGACGCAGCGCGCCGCCATGGTGTTCCCGACGACAACCCACATTAGCGCGCTCCTAGGAGAG
CGGCCGACGGGCCGCTTATT

Downstream 100 bases:

>100_bases
ACCCTTTAAAAGAGATGAACTTTATTCCGGCTCCCCAATAGGAGTCGTCGCGGAACAAAGACGATGAAGGTAGCGATCGT
GGGAAACGGCTTCGCCGCGC

Product: ribosomal RNA methyltransferase NOP2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKHQEILKKLKDLKITKEDKLLARKYGYLPYMVRRYREMLGDPLPLLEAFEVPPKPTIRCNFLKVGCGKLKERLESRGFV
LKQVLWCPHAYEVLREPFSLSSTPEHLDGWFYIQDKASTLPPLVLGPKPGETVADLASAPGGKATHLAQLMGNSGRLILI
ERRRDRAKALMSNLERMEILNANVIIDDAYNASKYGPFDKALLDAPCTGEGVIARDPSRKRSRRPEDLALMHKVQAMLLN
RALDSLKPGGELVYSTCSIAPEENELVIETILKTRDDVEVLDGGEAGSPGIEEYLGWEFPFAYKCRRLWPHVHGSEGFFV
CKLRKL

Sequences:

>Translated_326_residues
MKHQEILKKLKDLKITKEDKLLARKYGYLPYMVRRYREMLGDPLPLLEAFEVPPKPTIRCNFLKVGCGKLKERLESRGFV
LKQVLWCPHAYEVLREPFSLSSTPEHLDGWFYIQDKASTLPPLVLGPKPGETVADLASAPGGKATHLAQLMGNSGRLILI
ERRRDRAKALMSNLERMEILNANVIIDDAYNASKYGPFDKALLDAPCTGEGVIARDPSRKRSRRPEDLALMHKVQAMLLN
RALDSLKPGGELVYSTCSIAPEENELVIETILKTRDDVEVLDGGEAGSPGIEEYLGWEFPFAYKCRRLWPHVHGSEGFFV
CKLRKL
>Mature_326_residues
MKHQEILKKLKDLKITKEDKLLARKYGYLPYMVRRYREMLGDPLPLLEAFEVPPKPTIRCNFLKVGCGKLKERLESRGFV
LKQVLWCPHAYEVLREPFSLSSTPEHLDGWFYIQDKASTLPPLVLGPKPGETVADLASAPGGKATHLAQLMGNSGRLILI
ERRRDRAKALMSNLERMEILNANVIIDDAYNASKYGPFDKALLDAPCTGEGVIARDPSRKRSRRPEDLALMHKVQAMLLN
RALDSLKPGGELVYSTCSIAPEENELVIETILKTRDDVEVLDGGEAGSPGIEEYLGWEFPFAYKCRRLWPHVHGSEGFFV
CKLRKL

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=344, Percent_Identity=34.3023255813954, Blast_Score=178, Evalue=5e-45,
Organism=Homo sapiens, GI76150623, Length=344, Percent_Identity=34.3023255813954, Blast_Score=178, Evalue=5e-45,
Organism=Homo sapiens, GI32698918, Length=187, Percent_Identity=33.1550802139037, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI23199998, Length=239, Percent_Identity=30.1255230125523, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI8922322, Length=239, Percent_Identity=30.1255230125523, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI270288818, Length=239, Percent_Identity=30.1255230125523, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI270288816, Length=239, Percent_Identity=30.1255230125523, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40316918, Length=236, Percent_Identity=29.6610169491525, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI11545785, Length=200, Percent_Identity=35, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI39995082, Length=392, Percent_Identity=24.4897959183673, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI301336155, Length=370, Percent_Identity=24.0540540540541, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081985, Length=317, Percent_Identity=34.7003154574132, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI2367212, Length=235, Percent_Identity=32.7659574468085, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17536757, Length=318, Percent_Identity=38.3647798742138, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71998419, Length=226, Percent_Identity=31.858407079646, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI115534021, Length=226, Percent_Identity=31.858407079646, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25143471, Length=278, Percent_Identity=27.6978417266187, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324268, Length=311, Percent_Identity=36.0128617363344, Blast_Score=191, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6319447, Length=262, Percent_Identity=27.4809160305344, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324306, Length=269, Percent_Identity=27.5092936802974, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI22024126, Length=310, Percent_Identity=37.4193548387097, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24668781, Length=232, Percent_Identity=29.3103448275862, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21356513, Length=232, Percent_Identity=29.3103448275862, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920494, Length=175, Percent_Identity=34.8571428571429, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355201, Length=284, Percent_Identity=26.4084507042254, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21356579, Length=178, Percent_Identity=26.9662921348315, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR011023 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu [H]

EC number: NA

Molecular weight: Translated: 36842; Mature: 36842

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHQEILKKLKDLKITKEDKLLARKYGYLPYMVRRYREMLGDPLPLLEAFEVPPKPTIRC
CCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEE
NFLKVGCGKLKERLESRGFVLKQVLWCPHAYEVLREPFSLSSTPEHLDGWFYIQDKASTL
EEEECCHHHHHHHHHHCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCC
PPLVLGPKPGETVADLASAPGGKATHLAQLMGNSGRLILIERRRDRAKALMSNLERMEIL
CCEEECCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHH
NANVIIDDAYNASKYGPFDKALLDAPCTGEGVIARDPSRKRSRRPEDLALMHKVQAMLLN
CCCEEEECCCCCCCCCCHHHHHHCCCCCCCCEEECCCCHHHHCCCHHHHHHHHHHHHHHH
RALDSLKPGGELVYSTCSIAPEENELVIETILKTRDDVEVLDGGEAGSPGIEEYLGWEFP
HHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCHHHHCCCCCC
FAYKCRRLWPHVHGSEGFFVCKLRKL
HHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKHQEILKKLKDLKITKEDKLLARKYGYLPYMVRRYREMLGDPLPLLEAFEVPPKPTIRC
CCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEE
NFLKVGCGKLKERLESRGFVLKQVLWCPHAYEVLREPFSLSSTPEHLDGWFYIQDKASTL
EEEECCHHHHHHHHHHCCHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCC
PPLVLGPKPGETVADLASAPGGKATHLAQLMGNSGRLILIERRRDRAKALMSNLERMEIL
CCEEECCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHH
NANVIIDDAYNASKYGPFDKALLDAPCTGEGVIARDPSRKRSRRPEDLALMHKVQAMLLN
CCCEEEECCCCCCCCCCHHHHHHCCCCCCCCEEECCCCHHHHCCCHHHHHHHHHHHHHHH
RALDSLKPGGELVYSTCSIAPEENELVIETILKTRDDVEVLDGGEAGSPGIEEYLGWEFP
HHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCHHHHCCCCCC
FAYKCRRLWPHVHGSEGFFVCKLRKL
HHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]