Click here to switch to the map view.

The map label for this gene is nrdD [C]

Identifier: 156936831

GI number: 156936831

Start: 33252

End: 35234

Strand: Reverse

Name: nrdD [C]

Synonym: Igni_0036

Alternate gene names: 156936831

Gene position: 35234-33252 (Counterclockwise)

Preceding gene: 156936832

Following gene: 156936830

Centisome position: 2.72

GC content: 54.92

Gene sequence:

>1983_bases
TTGATTCGTCCAAAGCATTCTAACACTAAACGGCGACCGCGAATGGCTAGGGTAGGCGACCACCTAACCACTCTCGGGTT
TACAAACGTCAAGAAGCCTAGAAACGTACTCGAAGAAATGATGGGTAGGAGCGTCAACTCCAACGAGTACCAGGGTCCCA
ACAAACTGCTGCTAGAAGCGGCCGAGAGGTACCTCTGGGAACACGTAGTAGAGGACGTTATGCCCAAGGACATGATAAGC
GCTCACAAAGAAGGTGTAGTGTACGTACACAAACTGCCCCAGAGCGTCTTCCTCCCCTACTGCAACGGCAACGACTACTC
CAGAGTACTGAAGAAGGGCTTGAAGACCCCCACCATAGTGGCGGGCCCGGCGAGGCACTACCAAGTAGCGATGGCCCACG
CTGCTAACTTCCTAGCTATGATGCAGCAGTACTGGACCGGCGCCCAAGCGTTCGGCAGCGTGGAGCTGTGGGTAGCGCCC
TTCATAGCCAAGGAACACCTAAGCGACGAGGAAATAAGGCAAGGGATCCAGACGCTCTACTACGAACTCAACTTGCCGTG
GAGACCCGGGATGCAAACGCCCTTCACGAACATCACTGTAACCTACACCGAAAGCAAGTACATGTTAGACCAACCCGTAA
TAATAGGTGGCGCCTCCACCGGAGACCTCTTGGGAGACTACTTAGACGAGGCCCGCAGGTGGCTCATCCAGCTGGGCAAG
GTCCTCCAGAGGGGCGACTCGCTCCGGCAGCCGTTTACCTTCCCCATACCGACGTTAATGCCCACTGCCAAGGACTTCTA
CAACGACGCCGAACTCTTCGACGCCATCTTCGTGACTGCTGCAAAGATGGGAAGCTACTACTGGCTCAACACCAAGGTTA
TAGACCCTGACTCCGCGTTCGCGATGTGCTGCCGCTACGTAGTAAAGAAGGACGAAGTCAACAAGGCATTCATGGGAGGG
TTGAGGCTGAAGAAGTTGGAAGATCAAAGGAAGGAAGAGCTAGAGAAGTTGGCAAAGGGCAGGCTGGGCGGAATGTGGGC
CATACCCGACATAACTGGCAGCATCGGCGTGGTCACCGTTAACCTGCCCAGAATAGCCTTGGACGCCAGGGGAGATGTGG
AGACCTTCTTCGAGATACTGGAAGAGAGAGTAGAGCTGGTGGCCAAGTGGCTGAGCTGGTGGAGGAACCACTACCTAAGG
CTGATGAAGACGTATAGGAACTTCTACAGCATGGTGTGGGAATACAGCCCCGAGTGGACGAGAACCCACTTCAACACTAT
AGGGGCAATAGGGATGCCGGAGGCCGCGGCGATCCTATTAGGAGATCCCGAAGTGTGGACCAGCGAGGACGTAGGCGCGA
AGGAGAAGGCAATAGAACTGGAGGACAAGATGATAAAGACTATGGCTGACATAGCCTCCAGATTAACCATCGAAATGGGC
GAGCCGTTCAACGTTGAGGAAGTACCCGGAGAGACCGCCGCGGCAAAGTTGTTCTTAAACGACTTGAAGCATTACCCCGA
AGTAAGGGAATACGTGCCCGAAGGGGTCGACATGTATTCCACCAGCGTAGTGCCCTATTACGACCACGGCATAACTCTAT
GGCAGAGGATAAAGTGGGAGGGCAAGGTCCAACAGAGGTTCACCGGAGGAGTAATGATGCACATATTCCTCGGCGAGCAG
CCGGACCCGGAGGCGCTCGCGAAGCTAACCCAAAAGATCATGGACGCCGGAGTGGTCTACTGGAGCTATACGCCGGCCAT
AAGCGTCTGCGAGAACGGCCACAAGACTGTGGGCCTCTACACTAGGTGCCCGAGGTGCGGAGCCAAGACGGAGATATGGA
GCAGAATAATAGGTTACTACAGGCCGGTGAGCAACTGGAACCCGTTCAGGCAGAAGGAGTTCCGCATGAGGACCCACTAC
GACAACAGCTTAAACAAGGGCAAGCTCGCTGTGTACAGCCTCGAGGACGGTAGGCCTATGTAA

Upstream 100 bases:

>100_bases
AGCAAGACTTTCGACATTCTCAATCTTATCTCGAGAAGGCATTAAGCGTACTACTGCTACCTCTTTAGCCTAGTATCACG
CAAGTAACGCACGCTATTTA

Downstream 100 bases:

>100_bases
CGAGGTAGCTCGTCATCCTTTAAATTATATTTTTATATTTTCTCCTGGTCCCCAGCCTCTGGGTAAGGGAATGCCTGCGG
CCGGCGGAATCGGCGCGCTA

Product: anaerobic ribonucleoside triphosphate reductase

Products: ribonucleoside triphosphate; thioredoxin

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MIRPKHSNTKRRPRMARVGDHLTTLGFTNVKKPRNVLEEMMGRSVNSNEYQGPNKLLLEAAERYLWEHVVEDVMPKDMIS
AHKEGVVYVHKLPQSVFLPYCNGNDYSRVLKKGLKTPTIVAGPARHYQVAMAHAANFLAMMQQYWTGAQAFGSVELWVAP
FIAKEHLSDEEIRQGIQTLYYELNLPWRPGMQTPFTNITVTYTESKYMLDQPVIIGGASTGDLLGDYLDEARRWLIQLGK
VLQRGDSLRQPFTFPIPTLMPTAKDFYNDAELFDAIFVTAAKMGSYYWLNTKVIDPDSAFAMCCRYVVKKDEVNKAFMGG
LRLKKLEDQRKEELEKLAKGRLGGMWAIPDITGSIGVVTVNLPRIALDARGDVETFFEILEERVELVAKWLSWWRNHYLR
LMKTYRNFYSMVWEYSPEWTRTHFNTIGAIGMPEAAAILLGDPEVWTSEDVGAKEKAIELEDKMIKTMADIASRLTIEMG
EPFNVEEVPGETAAAKLFLNDLKHYPEVREYVPEGVDMYSTSVVPYYDHGITLWQRIKWEGKVQQRFTGGVMMHIFLGEQ
PDPEALAKLTQKIMDAGVVYWSYTPAISVCENGHKTVGLYTRCPRCGAKTEIWSRIIGYYRPVSNWNPFRQKEFRMRTHY
DNSLNKGKLAVYSLEDGRPM

Sequences:

>Translated_660_residues
MIRPKHSNTKRRPRMARVGDHLTTLGFTNVKKPRNVLEEMMGRSVNSNEYQGPNKLLLEAAERYLWEHVVEDVMPKDMIS
AHKEGVVYVHKLPQSVFLPYCNGNDYSRVLKKGLKTPTIVAGPARHYQVAMAHAANFLAMMQQYWTGAQAFGSVELWVAP
FIAKEHLSDEEIRQGIQTLYYELNLPWRPGMQTPFTNITVTYTESKYMLDQPVIIGGASTGDLLGDYLDEARRWLIQLGK
VLQRGDSLRQPFTFPIPTLMPTAKDFYNDAELFDAIFVTAAKMGSYYWLNTKVIDPDSAFAMCCRYVVKKDEVNKAFMGG
LRLKKLEDQRKEELEKLAKGRLGGMWAIPDITGSIGVVTVNLPRIALDARGDVETFFEILEERVELVAKWLSWWRNHYLR
LMKTYRNFYSMVWEYSPEWTRTHFNTIGAIGMPEAAAILLGDPEVWTSEDVGAKEKAIELEDKMIKTMADIASRLTIEMG
EPFNVEEVPGETAAAKLFLNDLKHYPEVREYVPEGVDMYSTSVVPYYDHGITLWQRIKWEGKVQQRFTGGVMMHIFLGEQ
PDPEALAKLTQKIMDAGVVYWSYTPAISVCENGHKTVGLYTRCPRCGAKTEIWSRIIGYYRPVSNWNPFRQKEFRMRTHY
DNSLNKGKLAVYSLEDGRPM
>Mature_660_residues
MIRPKHSNTKRRPRMARVGDHLTTLGFTNVKKPRNVLEEMMGRSVNSNEYQGPNKLLLEAAERYLWEHVVEDVMPKDMIS
AHKEGVVYVHKLPQSVFLPYCNGNDYSRVLKKGLKTPTIVAGPARHYQVAMAHAANFLAMMQQYWTGAQAFGSVELWVAP
FIAKEHLSDEEIRQGIQTLYYELNLPWRPGMQTPFTNITVTYTESKYMLDQPVIIGGASTGDLLGDYLDEARRWLIQLGK
VLQRGDSLRQPFTFPIPTLMPTAKDFYNDAELFDAIFVTAAKMGSYYWLNTKVIDPDSAFAMCCRYVVKKDEVNKAFMGG
LRLKKLEDQRKEELEKLAKGRLGGMWAIPDITGSIGVVTVNLPRIALDARGDVETFFEILEERVELVAKWLSWWRNHYLR
LMKTYRNFYSMVWEYSPEWTRTHFNTIGAIGMPEAAAILLGDPEVWTSEDVGAKEKAIELEDKMIKTMADIASRLTIEMG
EPFNVEEVPGETAAAKLFLNDLKHYPEVREYVPEGVDMYSTSVVPYYDHGITLWQRIKWEGKVQQRFTGGVMMHIFLGEQ
PDPEALAKLTQKIMDAGVVYWSYTPAISVCENGHKTVGLYTRCPRCGAKTEIWSRIIGYYRPVSNWNPFRQKEFRMRTHY
DNSLNKGKLAVYSLEDGRPM

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2

Molecular weight: Translated: 75696; Mature: 75696

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPKHSNTKRRPRMARVGDHLTTLGFTNVKKPRNVLEEMMGRSVNSNEYQGPNKLLLEA
CCCCCCCCCCCCCHHHHHCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AERYLWEHVVEDVMPKDMISAHKEGVVYVHKLPQSVFLPYCNGNDYSRVLKKGLKTPTIV
HHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCHHEEECCCCCCHHHHHHHCCCCCEEE
AGPARHYQVAMAHAANFLAMMQQYWTGAQAFGSVELWVAPFIAKEHLSDEEIRQGIQTLY
ECCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEHHHHHHHHHHCCCHHHHHHHHHHHH
YELNLPWRPGMQTPFTNITVTYTESKYMLDQPVIIGGASTGDLLGDYLDEARRWLIQLGK
HEECCCCCCCCCCCCCEEEEEEECCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
VLQRGDSLRQPFTFPIPTLMPTAKDFYNDAELFDAIFVTAAKMGSYYWLNTKVIDPDSAF
HHHCCCHHCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHH
AMCCRYVVKKDEVNKAFMGGLRLKKLEDQRKEELEKLAKGRLGGMWAIPDITGSIGVVTV
HHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEE
NLPRIALDARGDVETFFEILEERVELVAKWLSWWRNHYLRLMKTYRNFYSMVWEYSPEWT
ECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RTHFNTIGAIGMPEAAAILLGDPEVWTSEDVGAKEKAIELEDKMIKTMADIASRLTIEMG
HHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECC
EPFNVEEVPGETAAAKLFLNDLKHYPEVREYVPEGVDMYSTSVVPYYDHGITLWQRIKWE
CCCCHHHCCCCHHHHHHHHHHHHHCHHHHHHCCCCCCHHHCCCCEEECCCHHHHHHHCCC
GKVQQRFTGGVMMHIFLGEQPDPEALAKLTQKIMDAGVVYWSYTPAISVCENGHKTVGLY
CHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCCEEEEE
TRCPRCGAKTEIWSRIIGYYRPVSNWNPFRQKEFRMRTHYDNSLNKGKLAVYSLEDGRPM
ECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MIRPKHSNTKRRPRMARVGDHLTTLGFTNVKKPRNVLEEMMGRSVNSNEYQGPNKLLLEA
CCCCCCCCCCCCCHHHHHCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AERYLWEHVVEDVMPKDMISAHKEGVVYVHKLPQSVFLPYCNGNDYSRVLKKGLKTPTIV
HHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCHHEEECCCCCCHHHHHHHCCCCCEEE
AGPARHYQVAMAHAANFLAMMQQYWTGAQAFGSVELWVAPFIAKEHLSDEEIRQGIQTLY
ECCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEHHHHHHHHHHCCCHHHHHHHHHHHH
YELNLPWRPGMQTPFTNITVTYTESKYMLDQPVIIGGASTGDLLGDYLDEARRWLIQLGK
HEECCCCCCCCCCCCCEEEEEEECCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
VLQRGDSLRQPFTFPIPTLMPTAKDFYNDAELFDAIFVTAAKMGSYYWLNTKVIDPDSAF
HHHCCCHHCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHH
AMCCRYVVKKDEVNKAFMGGLRLKKLEDQRKEELEKLAKGRLGGMWAIPDITGSIGVVTV
HHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEE
NLPRIALDARGDVETFFEILEERVELVAKWLSWWRNHYLRLMKTYRNFYSMVWEYSPEWT
ECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RTHFNTIGAIGMPEAAAILLGDPEVWTSEDVGAKEKAIELEDKMIKTMADIASRLTIEMG
HHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECC
EPFNVEEVPGETAAAKLFLNDLKHYPEVREYVPEGVDMYSTSVVPYYDHGITLWQRIKWE
CCCCHHHCCCCHHHHHHHHHHHHHCHHHHHHCCCCCCHHHCCCCEEECCCHHHHHHHCCC
GKVQQRFTGGVMMHIFLGEQPDPEALAKLTQKIMDAGVVYWSYTPAISVCENGHKTVGLY
CHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCCEEEEE
TRCPRCGAKTEIWSRIIGYYRPVSNWNPFRQKEFRMRTHYDNSLNKGKLAVYSLEDGRPM
ECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside triphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]