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The map label for this gene is aroB [H]

Identifier: 156936813

GI number: 156936813

Start: 19735

End: 20838

Strand: Direct

Name: aroB [H]

Synonym: Igni_0018

Alternate gene names: 156936813

Gene position: 19735-20838 (Clockwise)

Preceding gene: 156936812

Following gene: 156936815

Centisome position: 1.52

GC content: 53.26

Gene sequence:

>1104_bases
TTGAGGAGCTCGTCTAGATTGGAGGTCCCAATCACCGAAGAACACACTTACAAAGTAATAATCGGGAGGAACGTCTTCAA
AGAAGTCGAGAGCGCCTTGCCGGAGAACGTTAAGCCGTGTCTCGCGGTGGTAGGCGAAGGGGTGGCAAAGGGCGCACGGT
GGGTCCTCAAAGAGGCGAGCGCAGTCTTCCCCCATTGGGAGATACTCAAGGACGGCGAGGCCGCGAAGGATCTGAGCGTG
GCCTTGAACATTATTAGAAAGCTCTGGGAACTGAAGGCCGACCGCTGGTGTGCCCTAGGAGTGATAGCCGGGGGCAGCTT
AGGCGATACAGCCTCCTTCGCTGCCTCCGTCTACATGAGGGGGATACCGTTGATCCAGTTCCCCACGACGCTGTTAGCCA
TGATAGACAGCTCGCTGGGCGGAAAAACTGCGGTTAACTTCGAAGGCTTTAAAAACGTACTGGGCTCGTTCTACCACCCG
TGGTTAGTAGTTGATGACTTGAGGTTTCTGGACACCTTACCGGACAGAGTCTTCAAATCCAGCATGGCAGAAGCAATAAA
GTACGGAATCACTTTGAATCCCGAGTTCTTGAAGTACTTAAAAGACAACAGCTCGAAGATCTTGGCGAGAGACGACGAAT
ACGTATCGAAAGTTATTGCAGAAAGTGTCAAAACAAAGCTCGAAGTGGTTAGGAAGGACCCCAGAGAACGAAAGGGAGTC
CGAGAGGTGCTGAACTTCGGCCACACCGTAGGCCACGCCCTCGAGTCGGCCTCCAAGTTCGAGCTGCTCCACGGCGAAGC
CGTGGCCCTCGGAATGGTCGTCGAGACCTTATACGCCGAGAGGGTAGGGGCGTGTTCCTCTTGTTACGAAGCCTTAGAGG
GCGCGCTCTCGGCTTATTCGTTAACCCAAGTTAAGGCTCCTAAGATGACCATAGAAGAGTACAAAGCTATGATACTGAAG
GACAAGAAGAGGGTAGGCGACCGCTTGAGGTTACCCTTACTAGAGGGGGTGGGAAGGTGGAGGCTGGAGCTGGTCCCCTT
GGACGAATTCGTCGAGACCACGTTCAAAATCATGGAAGAAGTGTTTTGGTCAGAGGACTTCTAA

Upstream 100 bases:

>100_bases
GGCAACCCAGTACTACTAATAGCAGTCGTACTGGTAGGCGCGGCCGGAGCGTATTTGGCTTCGATGTTCGTGGGTAGGGG
AGGCGAGGAGGAGGAGATAT

Downstream 100 bases:

>100_bases
CCCTATGGCCAGCGCGGGGCCCGCTTCGGGTCCGTAGTACTTCTCGTAGACCTTGAGTCCCTCCTCGACGCTCAGCCCGG
GCAACACTCTGTCCTCGCTT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MRSSSRLEVPITEEHTYKVIIGRNVFKEVESALPENVKPCLAVVGEGVAKGARWVLKEASAVFPHWEILKDGEAAKDLSV
ALNIIRKLWELKADRWCALGVIAGGSLGDTASFAASVYMRGIPLIQFPTTLLAMIDSSLGGKTAVNFEGFKNVLGSFYHP
WLVVDDLRFLDTLPDRVFKSSMAEAIKYGITLNPEFLKYLKDNSSKILARDDEYVSKVIAESVKTKLEVVRKDPRERKGV
REVLNFGHTVGHALESASKFELLHGEAVALGMVVETLYAERVGACSSCYEALEGALSAYSLTQVKAPKMTIEEYKAMILK
DKKRVGDRLRLPLLEGVGRWRLELVPLDEFVETTFKIMEEVFWSEDF

Sequences:

>Translated_367_residues
MRSSSRLEVPITEEHTYKVIIGRNVFKEVESALPENVKPCLAVVGEGVAKGARWVLKEASAVFPHWEILKDGEAAKDLSV
ALNIIRKLWELKADRWCALGVIAGGSLGDTASFAASVYMRGIPLIQFPTTLLAMIDSSLGGKTAVNFEGFKNVLGSFYHP
WLVVDDLRFLDTLPDRVFKSSMAEAIKYGITLNPEFLKYLKDNSSKILARDDEYVSKVIAESVKTKLEVVRKDPRERKGV
REVLNFGHTVGHALESASKFELLHGEAVALGMVVETLYAERVGACSSCYEALEGALSAYSLTQVKAPKMTIEEYKAMILK
DKKRVGDRLRLPLLEGVGRWRLELVPLDEFVETTFKIMEEVFWSEDF
>Mature_367_residues
MRSSSRLEVPITEEHTYKVIIGRNVFKEVESALPENVKPCLAVVGEGVAKGARWVLKEASAVFPHWEILKDGEAAKDLSV
ALNIIRKLWELKADRWCALGVIAGGSLGDTASFAASVYMRGIPLIQFPTTLLAMIDSSLGGKTAVNFEGFKNVLGSFYHP
WLVVDDLRFLDTLPDRVFKSSMAEAIKYGITLNPEFLKYLKDNSSKILARDDEYVSKVIAESVKTKLEVVRKDPRERKGV
REVLNFGHTVGHALESASKFELLHGEAVALGMVVETLYAERVGACSSCYEALEGALSAYSLTQVKAPKMTIEEYKAMILK
DKKRVGDRLRLPLLEGVGRWRLELVPLDEFVETTFKIMEEVFWSEDF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=333, Percent_Identity=39.039039039039, Blast_Score=180, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320332, Length=310, Percent_Identity=33.5483870967742, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40981; Mature: 40981

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSSRLEVPITEEHTYKVIIGRNVFKEVESALPENVKPCLAVVGEGVAKGARWVLKEAS
CCCCCCEECEECCCCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVFPHWEILKDGEAAKDLSVALNIIRKLWELKADRWCALGVIAGGSLGDTASFAASVYMR
HHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHC
GIPLIQFPTTLLAMIDSSLGGKTAVNFEGFKNVLGSFYHPWLVVDDLRFLDTLPDRVFKS
CCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHH
SMAEAIKYGITLNPEFLKYLKDNSSKILARDDEYVSKVIAESVKTKLEVVRKDPRERKGV
HHHHHHHHCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
REVLNFGHTVGHALESASKFELLHGEAVALGMVVETLYAERVGACSSCYEALEGALSAYS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LTQVKAPKMTIEEYKAMILKDKKRVGDRLRLPLLEGVGRWRLELVPLDEFVETTFKIMEE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECHHHHHHHHHHHHHH
VFWSEDF
HHCCCCC
>Mature Secondary Structure
MRSSSRLEVPITEEHTYKVIIGRNVFKEVESALPENVKPCLAVVGEGVAKGARWVLKEAS
CCCCCCEECEECCCCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVFPHWEILKDGEAAKDLSVALNIIRKLWELKADRWCALGVIAGGSLGDTASFAASVYMR
HHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHC
GIPLIQFPTTLLAMIDSSLGGKTAVNFEGFKNVLGSFYHPWLVVDDLRFLDTLPDRVFKS
CCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHH
SMAEAIKYGITLNPEFLKYLKDNSSKILARDDEYVSKVIAESVKTKLEVVRKDPRERKGV
HHHHHHHHCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
REVLNFGHTVGHALESASKFELLHGEAVALGMVVETLYAERVGACSSCYEALEGALSAYS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LTQVKAPKMTIEEYKAMILKDKKRVGDRLRLPLLEGVGRWRLELVPLDEFVETTFKIMEE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECHHHHHHHHHHHHHH
VFWSEDF
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]