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The map label for this gene is phoP [H]

Identifier: 156936560

GI number: 156936560

Start: 11412

End: 12104

Strand: Direct

Name: phoP [H]

Synonym: ESA_pESA3p05441

Alternate gene names: 156936560

Gene position: 11412-12104 (Clockwise)

Preceding gene: 156936557

Following gene: 156936561

Centisome position: 8.7

GC content: 60.17

Gene sequence:

>693_bases
ATGACAACCAAAAGGGTACTTGTGATTGAGGATGACGCCGATGCCGCCAGCGTACTGGAGGCCTATCTGCGGCGTGAAAA
TTACGACGTGGCGATCGCGGGAGATGGTCGCAGCGGGCTTGAAAAAGCGCAACGCTGGAAACCGGATCTGGTGCTGCTGG
ATGTGATGCTGCCTGTCATGAACGGCACCGAAGTGCTGGCGACCCTGCGGCGCAGCAGCGATGTTCCGGTGATCATGGTG
ACGGCCATGGGCGATACGCCCGATCGCATCGGCGCGCTGCGCTACGGGGCCGATGATTATGTGGTGAAGCCTTATCATCC
TGGCGAAGTGGTCGCGCGCGTGCAGGCGGTGCTGCGTCGGAGTTGCAAAGCACCGGTGCAGGACGAAATACTGCGCTGGG
AAACGCTCACCGTGGATACGGTCGCTATCACCGCGACGACAGACCGGGACGGCGTAACCACATACCTTGAGCTCACTCCC
ACTGAATTTTCTTTGCTTACCGAGCTGATGCGCCATCCCACGCGTCCTTTTTCCCGTCAGTACCTGCTTGAGCGCTGCCT
GCCGGAGAGCGAGGCGCTGGAACGCGTTGTCGACACGCACATCTATAACCTGCGCAGAAAGCTTGAGAATAGCGGCCTGC
GCGGGGTGCTGGTCAATGTGCGCGGCATCGGTTACCGGTTTCGCCAGCCATGA

Upstream 100 bases:

>100_bases
TGTATGGCTGAACGGCTGGCTACCGTGTTCGACGCGCATTCTGGGCCACTCATATCAATGAACGGTCAGGAAACTGTTAA
GAAACTGTCAAGGTGAACAG

Downstream 100 bases:

>100_bases
ATAACCATCATCAGTCTCTCTGGCGCTGGATCTGCGGGCGCATAATTTCGCTCGCCGTCGGGACAGTTATCGTTATCGCC
GTCTGCATGTGGCTGCGCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTTKRVLVIEDDADAASVLEAYLRRENYDVAIAGDGRSGLEKAQRWKPDLVLLDVMLPVMNGTEVLATLRRSSDVPVIMV
TAMGDTPDRIGALRYGADDYVVKPYHPGEVVARVQAVLRRSCKAPVQDEILRWETLTVDTVAITATTDRDGVTTYLELTP
TEFSLLTELMRHPTRPFSRQYLLERCLPESEALERVVDTHIYNLRRKLENSGLRGVLVNVRGIGYRFRQP

Sequences:

>Translated_230_residues
MTTKRVLVIEDDADAASVLEAYLRRENYDVAIAGDGRSGLEKAQRWKPDLVLLDVMLPVMNGTEVLATLRRSSDVPVIMV
TAMGDTPDRIGALRYGADDYVVKPYHPGEVVARVQAVLRRSCKAPVQDEILRWETLTVDTVAITATTDRDGVTTYLELTP
TEFSLLTELMRHPTRPFSRQYLLERCLPESEALERVVDTHIYNLRRKLENSGLRGVLVNVRGIGYRFRQP
>Mature_229_residues
TTKRVLVIEDDADAASVLEAYLRRENYDVAIAGDGRSGLEKAQRWKPDLVLLDVMLPVMNGTEVLATLRRSSDVPVIMVT
AMGDTPDRIGALRYGADDYVVKPYHPGEVVARVQAVLRRSCKAPVQDEILRWETLTVDTVAITATTDRDGVTTYLELTPT
EFSLLTELMRHPTRPFSRQYLLERCLPESEALERVVDTHIYNLRRKLENSGLRGVLVNVRGIGYRFRQP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.9912663755458, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=38.961038961039, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI2367329, Length=210, Percent_Identity=40, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=35.3448275862069, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=34.1991341991342, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=30.7017543859649, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.9285714285714, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.0807174887892, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=32.1428571428571, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1787375, Length=236, Percent_Identity=30.5084745762712, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=27.7310924369748, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=30.4932735426009, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=31.6239316239316, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790437, Length=100, Percent_Identity=37, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787487, Length=105, Percent_Identity=31.4285714285714, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788905, Length=130, Percent_Identity=31.5384615384615, Blast_Score=61, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=102, Percent_Identity=29.4117647058824, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25971; Mature: 25840

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKRVLVIEDDADAASVLEAYLRRENYDVAIAGDGRSGLEKAQRWKPDLVLLDVMLPVM
CCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEEHHHHHHHC
NGTEVLATLRRSSDVPVIMVTAMGDTPDRIGALRYGADDYVVKPYHPGEVVARVQAVLRR
CCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHEEECCCCCEECCCCCHHHHHHHHHHHHH
SCKAPVQDEILRWETLTVDTVAITATTDRDGVTTYLELTPTEFSLLTELMRHPTRPFSRQ
HCCCCHHHHHHHHEEEEEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHHH
YLLERCLPESEALERVVDTHIYNLRRKLENSGLRGVLVNVRGIGYRFRQP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEECCC
>Mature Secondary Structure 
TTKRVLVIEDDADAASVLEAYLRRENYDVAIAGDGRSGLEKAQRWKPDLVLLDVMLPVM
CCCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEEHHHHHHHC
NGTEVLATLRRSSDVPVIMVTAMGDTPDRIGALRYGADDYVVKPYHPGEVVARVQAVLRR
CCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHEEECCCCCEECCCCCHHHHHHHHHHHHH
SCKAPVQDEILRWETLTVDTVAITATTDRDGVTTYLELTPTEFSLLTELMRHPTRPFSRQ
HCCCCHHHHHHHHEEEEEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHHH
YLLERCLPESEALERVVDTHIYNLRRKLENSGLRGVLVNVRGIGYRFRQP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]