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The map label for this gene is cobC [H]

Identifier: 156936547

GI number: 156936547

Start: 837

End: 1574

Strand: Direct

Name: cobC [H]

Synonym: ESA_pESA3p05428

Alternate gene names: 156936547

Gene position: 837-1574 (Clockwise)

Preceding gene: NA

Following gene: 156936548

Centisome position: 0.64

GC content: 57.32

Gene sequence:

>738_bases
GTGATTACCTTCATAATTTTCCGCGAGTCTTCTGTCTTTTCCATAACGGAAACAGGGGGCCTTTACCGTTTTAGCATGGC
GGTCTGTGACCGGAACCGCTTTTTTGCAGGGAATGACGTTATGAATCTTCTCCTTATCCGTCATGCCGAAACAGAATGGA
ACCGTGGCGGGCTCATTCAGGGGCATCATGACAGCGCGCTGACGGCGCGTGGCTTGCAGGAAACCACAGCGCTCCTGACT
GCTCTGGCGCACGAATTCCCCTCTGTTGACGCGGTGTACACATCTCCCGCGGGCCGCGCGCGCCATATGGGTGACGCCAT
CGCGAGCCATTTTCGCTGCCCACTCTCTGTTGAGCCTCTATTACGTGAGCAGGCGTTTGGTGATTACGAAGGCCTGTCGC
GGGTGCAGTTGCAGCGAGATGAGCCTCTCAGCGCAGAAGCGCTGTTTTCAACTGATGCGTTATTTACGCCGCCCGGCGGT
GAATCGCTCGCGTATGCCGCGCAGCGTCTTCTGTCTTTCATCCAGAATGATCTCGCCGCAACCTCACACGCAACCTGCTG
CGTCGTGACGCACGGGCATATCCTTCAGGGCGCGCTGGCGCTCCTCAAAGACGGCAATATCGATAACTTCCCGCGCTATG
CGCAGCCTAACGCCAGCTATGCGCGGTTAACGTTTACGGCGGACCGCTGCGACGTCATTCAGTGGGGCATCGCGACCCAT
TTGCGACACCTGTCATAA

Upstream 100 bases:

>100_bases
TTGGATCCTGAAACACCGTGAATAATCTGGCGATTTCAGCGTGAAACTCTGATTCTTAATTCTGTAAAAACAGCGAGTTA
GAGGTAAAAGAGCGTGGCGA

Downstream 100 bases:

>100_bases
ACGCCGAAAACTTTCGCCGCTCTTAAGTCTTCCTTAAGATTAATCCTATAACTTCACTCTGGATCCTGCCCCTGTCGGGC
CGTACCGGAGCACACTCTAT

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MITFIIFRESSVFSITETGGLYRFSMAVCDRNRFFAGNDVMNLLLIRHAETEWNRGGLIQGHHDSALTARGLQETTALLT
ALAHEFPSVDAVYTSPAGRARHMGDAIASHFRCPLSVEPLLREQAFGDYEGLSRVQLQRDEPLSAEALFSTDALFTPPGG
ESLAYAAQRLLSFIQNDLAATSHATCCVVTHGHILQGALALLKDGNIDNFPRYAQPNASYARLTFTADRCDVIQWGIATH
LRHLS

Sequences:

>Translated_245_residues
MITFIIFRESSVFSITETGGLYRFSMAVCDRNRFFAGNDVMNLLLIRHAETEWNRGGLIQGHHDSALTARGLQETTALLT
ALAHEFPSVDAVYTSPAGRARHMGDAIASHFRCPLSVEPLLREQAFGDYEGLSRVQLQRDEPLSAEALFSTDALFTPPGG
ESLAYAAQRLLSFIQNDLAATSHATCCVVTHGHILQGALALLKDGNIDNFPRYAQPNASYARLTFTADRCDVIQWGIATH
LRHLS
>Mature_245_residues
MITFIIFRESSVFSITETGGLYRFSMAVCDRNRFFAGNDVMNLLLIRHAETEWNRGGLIQGHHDSALTARGLQETTALLT
ALAHEFPSVDAVYTSPAGRARHMGDAIASHFRCPLSVEPLLREQAFGDYEGLSRVQLQRDEPLSAEALFSTDALFTPPGG
ESLAYAAQRLLSFIQNDLAATSHATCCVVTHGHILQGALALLKDGNIDNFPRYAQPNASYARLTFTADRCDVIQWGIATH
LRHLS

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=162, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 26965; Mature: 26965

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFIIFRESSVFSITETGGLYRFSMAVCDRNRFFAGNDVMNLLLIRHAETEWNRGGLIQ
CEEEEEEECCCEEEEECCCCEEEEEEEEECCCCEECCHHHHHHHHHHCCCCCCCCCCCEE
GHHDSALTARGLQETTALLTALAHEFPSVDAVYTSPAGRARHMGDAIASHFRCPLSVEPL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCHH
LREQAFGDYEGLSRVQLQRDEPLSAEALFSTDALFTPPGGESLAYAAQRLLSFIQNDLAA
HHHHCCCCCCCCHHEEECCCCCCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
TSHATCCVVTHGHILQGALALLKDGNIDNFPRYAQPNASYARLTFTADRCDVIQWGIATH
CCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
LRHLS
HHHCC
>Mature Secondary Structure
MITFIIFRESSVFSITETGGLYRFSMAVCDRNRFFAGNDVMNLLLIRHAETEWNRGGLIQ
CEEEEEEECCCEEEEECCCCEEEEEEEEECCCCEECCHHHHHHHHHHCCCCCCCCCCCEE
GHHDSALTARGLQETTALLTALAHEFPSVDAVYTSPAGRARHMGDAIASHFRCPLSVEPL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCHH
LREQAFGDYEGLSRVQLQRDEPLSAEALFSTDALFTPPGGESLAYAAQRLLSFIQNDLAA
HHHHCCCCCCCCHHEEECCCCCCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHH
TSHATCCVVTHGHILQGALALLKDGNIDNFPRYAQPNASYARLTFTADRCDVIQWGIATH
CCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
LRHLS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]