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Identifier: 15679867

GI number: 15679867

Start: 1713056

End: 1713964

Strand: Direct

Name: Not Available

Synonym: MTH1879

Alternate gene names: 15679867

Gene position: 1713056-1713964 (Clockwise)

Preceding gene: 15679866

Following gene: 15679868

Centisome position: 97.81

GC content: 48.73

Gene sequence:

>909_bases
ATGGAAATCGCATACTTTTTAGGATGTATCATGAACAACAGGTACCCTGGAATTGAAAAGGCAACAAGAGTCCTCTTCGA
TAAACTCGGAATCGAACTCAAGGACATGGAAGGGGCATTCTGCTGCCCGGCACCAGGGGTCTTCGGTTCATTCGACAAGA
CAACATGGGCTGCAATAGCAGCAAGGAACATCACCATCGCTGAGGAGATGGGTTCAGACGTCATGACAGAATGTAACGGA
TGCTTCGGGTCACTGTTTGAAGCAAACCACCTCCTCAAGGAAGACGAGGAAATGAGGGCAAAAATCAATGAGATCCTCAA
GGAAGCAGGAAGGGAATACAAGGGTGAAATAAACGTAAGGCACCTGGCTGAAATTCTTTACAATGATGTGGGACTTGACA
AACTCTCAGAAGTCGTTGAAAAACCCCTCAACCTCAACGTGGCAGTGCACTACGGATGCCACTTCCTCAAACCAAGCGAA
GAGATAAACATAGACAACCCTGAAAGGCCAACAATACTGGACGAACTTGTTGAGGTCACCGGAGCAAAATCAGTTGACTA
CAAGGACAAGATGATGTGCTGCGGTGCCGGTGGTGGAGTAAGATCCAGGGACCTGGATGTTGCCCTGGACTTCACAATGG
AAAAACTCAGAAACATGAAGGAAGCAGGTGTGGATGCAATAGTCAACGTCTGCCCATTCTGCCACCTTCAGTTTGACGTG
GGTCAGATGGAGATCAAGGACAAGTTCGGTGAAGAATTCGACATACCAGTACTCCACCTTGCACAGCTGCTGGGACTTGC
AATGGGTCTTCCAAAAGAGGACCTTGTGGTTGACGCTCACCAGGTATGTGTCGACGAGTGCCTTGAAAAACTCGAGGAAC
TCGACCGCCTCGCACCTGGAAGCGGATAA

Upstream 100 bases:

>100_bases
AGCCCTTGAAGAGGTTCAGAAAATCATCAAGGCAACAGGCTTCGACCAGTTAATAGGATACAACTGGGAAACAGGTGAAC
TAGAATAGGGAGGCATGTAA

Downstream 100 bases:

>100_bases
ACCCCTAAATTATTTATTTTTTCAGGGGAGTTAAACTCCCATAAAGTAAACCAGAGGTGTTTTTTTGTTTATAGCCACTT
TAAAGGGAATATTCACCCTT

Product: heterodisulfide reductase, subunit B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MEIAYFLGCIMNNRYPGIEKATRVLFDKLGIELKDMEGAFCCPAPGVFGSFDKTTWAAIAARNITIAEEMGSDVMTECNG
CFGSLFEANHLLKEDEEMRAKINEILKEAGREYKGEINVRHLAEILYNDVGLDKLSEVVEKPLNLNVAVHYGCHFLKPSE
EINIDNPERPTILDELVEVTGAKSVDYKDKMMCCGAGGGVRSRDLDVALDFTMEKLRNMKEAGVDAIVNVCPFCHLQFDV
GQMEIKDKFGEEFDIPVLHLAQLLGLAMGLPKEDLVVDAHQVCVDECLEKLEELDRLAPGSG

Sequences:

>Translated_302_residues
MEIAYFLGCIMNNRYPGIEKATRVLFDKLGIELKDMEGAFCCPAPGVFGSFDKTTWAAIAARNITIAEEMGSDVMTECNG
CFGSLFEANHLLKEDEEMRAKINEILKEAGREYKGEINVRHLAEILYNDVGLDKLSEVVEKPLNLNVAVHYGCHFLKPSE
EINIDNPERPTILDELVEVTGAKSVDYKDKMMCCGAGGGVRSRDLDVALDFTMEKLRNMKEAGVDAIVNVCPFCHLQFDV
GQMEIKDKFGEEFDIPVLHLAQLLGLAMGLPKEDLVVDAHQVCVDECLEKLEELDRLAPGSG
>Mature_302_residues
MEIAYFLGCIMNNRYPGIEKATRVLFDKLGIELKDMEGAFCCPAPGVFGSFDKTTWAAIAARNITIAEEMGSDVMTECNG
CFGSLFEANHLLKEDEEMRAKINEILKEAGREYKGEINVRHLAEILYNDVGLDKLSEVVEKPLNLNVAVHYGCHFLKPSE
EINIDNPERPTILDELVEVTGAKSVDYKDKMMCCGAGGGVRSRDLDVALDFTMEKLRNMKEAGVDAIVNVCPFCHLQFDV
GQMEIKDKFGEEFDIPVLHLAQLLGLAMGLPKEDLVVDAHQVCVDECLEKLEELDRLAPGSG

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrB may have a function in energy transduction

COG id: COG2048

COG function: function code C; Heterodisulfide reductase, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hdrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HDRB_METTH (O27907)

Other databases:

- EMBL:   AE000666
- PIR:   D69118
- RefSeq:   NP_276985.1
- STRING:   O27907
- GeneID:   1470964
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1879
- NMPDR:   fig|187420.1.peg.1840
- eggNOG:   arNOG04955
- HOGENOM:   HBG513215
- OMA:   HYGCHFL
- ProtClustDB:   CLSK876313
- BioCyc:   MTHE187420:MTH1879-MONOMER
- BRENDA:   1.8.98.1
- GO:   GO:0015948
- InterPro:   IPR017678
- InterPro:   IPR004017
- TIGRFAMs:   TIGR03288

Pfam domain/function: PF02754 CCG

EC number: =1.8.98.1

Molecular weight: Translated: 33513; Mature: 33513

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAYFLGCIMNNRYPGIEKATRVLFDKLGIELKDMEGAFCCPAPGVFGSFDKTTWAAIA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCCCCEECCCCCCCCCCCHHHHHHHH
ARNITIAEEMGSDVMTECNGCFGSLFEANHLLKEDEEMRAKINEILKEAGREYKGEINVR
HCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHCCCCCHH
HLAEILYNDVGLDKLSEVVEKPLNLNVAVHYGCHFLKPSEEINIDNPERPTILDELVEVT
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECEEEECCCCCCCCCCCCCCHHHHHHHHHH
GAKSVDYKDKMMCCGAGGGVRSRDLDVALDFTMEKLRNMKEAGVDAIVNVCPFCHLQFDV
CCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECC
GQMEIKDKFGEEFDIPVLHLAQLLGLAMGLPKEDLVVDAHQVCVDECLEKLEELDRLAPG
CHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SG
CC
>Mature Secondary Structure
MEIAYFLGCIMNNRYPGIEKATRVLFDKLGIELKDMEGAFCCPAPGVFGSFDKTTWAAIA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCCCCEECCCCCCCCCCCHHHHHHHH
ARNITIAEEMGSDVMTECNGCFGSLFEANHLLKEDEEMRAKINEILKEAGREYKGEINVR
HCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHCCCCCHH
HLAEILYNDVGLDKLSEVVEKPLNLNVAVHYGCHFLKPSEEINIDNPERPTILDELVEVT
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECEEEECCCCCCCCCCCCCCHHHHHHHHHH
GAKSVDYKDKMMCCGAGGGVRSRDLDVALDFTMEKLRNMKEAGVDAIVNVCPFCHLQFDV
CCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECC
GQMEIKDKFGEEFDIPVLHLAQLLGLAMGLPKEDLVVDAHQVCVDECLEKLEELDRLAPG
CHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463