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Identifier: 15679783

GI number: 15679783

Start: 1641419

End: 1641778

Strand: Direct

Name: Not Available

Synonym: MTH1795

Alternate gene names: 15679783

Gene position: 1641419-1641778 (Clockwise)

Preceding gene: 15679776

Following gene: 15679784

Centisome position: 93.72

GC content: 46.94

Gene sequence:

>360_bases
ATGAAGAGGGATATCTGTGAAATTGAGCATACAGACAGGGAACGGGTGCTGAGGGTGAGGGCTGAAATGCCCTCCATCGA
TGATATAAGGGGGATCTGTGACATTTTTAAGATATTATCTGAGCCAACACGACTTAAGATACTCATGGCGCTTTCACTGG
ACTCCCTCTGCGTATGTGAACTGGCATCATTACTGGATGTAACCCAGTCAGCGGTTTCACATCAGCTGAGGATCCTCAGG
AACGCCGGGATGGTTGACTATGAGAGGGATGGTAAGATGGCGCGCTATTACCTAAGGGATAATATGGTTGTGGATTTCAT
AGAGCAGTGCAGTAAACTGCATTCACGGTGTGAGGAATAA

Upstream 100 bases:

>100_bases
CCCTTATCCTTATCCAGTCCACTGCCATTTTAATCCATCCGAATATTTCACCAGAGTCTCTGCGTTATTATTATCTACGG
TTCCATCTATAAAGTATTTC

Downstream 100 bases:

>100_bases
AAATGTATGAGCTGCTCTCCTATCACCTTGAGGACAGATCACCGGTCCACCCATCCCTTGAGGATGTCAGCATAACCATC
AACACCACTGTAGGGAATGA

Product: transcriptional regulator

Products: NA

Alternate protein names: Cadmium resistance regulatory protein [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MKRDICEIEHTDRERVLRVRAEMPSIDDIRGICDIFKILSEPTRLKILMALSLDSLCVCELASLLDVTQSAVSHQLRILR
NAGMVDYERDGKMARYYLRDNMVVDFIEQCSKLHSRCEE

Sequences:

>Translated_119_residues
MKRDICEIEHTDRERVLRVRAEMPSIDDIRGICDIFKILSEPTRLKILMALSLDSLCVCELASLLDVTQSAVSHQLRILR
NAGMVDYERDGKMARYYLRDNMVVDFIEQCSKLHSRCEE
>Mature_119_residues
MKRDICEIEHTDRERVLRVRAEMPSIDDIRGICDIFKILSEPTRLKILMALSLDSLCVCELASLLDVTQSAVSHQLRILR
NAGMVDYERDGKMARYYLRDNMVVDFIEQCSKLHSRCEE

Specific function: Metal-binding repressor for the cad operon. Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead. Metal binding causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13848; Mature: 13848

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDICEIEHTDRERVLRVRAEMPSIDDIRGICDIFKILSEPTRLKILMALSLDSLCVCE
CCCCCHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
LASLLDVTQSAVSHQLRILRNAGMVDYERDGKMARYYLRDNMVVDFIEQCSKLHSRCEE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRDICEIEHTDRERVLRVRAEMPSIDDIRGICDIFKILSEPTRLKILMALSLDSLCVCE
CCCCCHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
LASLLDVTQSAVSHQLRILRNAGMVDYERDGKMARYYLRDNMVVDFIEQCSKLHSRCEE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8188605; 8188606 [H]