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Identifier: 15679768

GI number: 15679768

Start: 1630646

End: 1631539

Strand: Direct

Name: Not Available

Synonym: MTH1780

Alternate gene names: 15679768

Gene position: 1630646-1631539 (Clockwise)

Preceding gene: 15679764

Following gene: 15679769

Centisome position: 93.11

GC content: 46.2

Gene sequence:

>894_bases
ATGGCTTTTAGTTTTACTTTAACTGTCAACTTCAGTATACTACCCTATTACGAAGGACAAGTTCCGCATCGAAATCTAGA
TATGGGCGCGGGTCCAGATAAACATACGGAAAGATGGGGGGAGGTGCATATGGATATTTTAACTGCAGGTTTGCTGGCTG
CTGTGATAATCGTTATTATTTCTCTGAGCCTGAAGATAGTTAAACAGTACGAGAGGGGTGTTGTTTTCAGACTGGGGAAG
GTTATAGGCGTCAGGGAGCCAGGTCTTCGCATAATAATCCCGATTATTGATCGCATGGTAAGGGTTTCACTTCGAATAGT
TACGATGCCCATACCATCCCAGAAGATAATAACACAGGACAATGTTTCAATAGATGTGGCCGCGGTTGCCTACTTCAAGG
TTGCAGACCCTCTCAGGGCCGTTGTTGCAATTGAGGACTATTATGGTGCGGTTAACCAGATATCCCAGACAACAGTCAGG
AACGTCATAGGCCAGTTTGTCCTTGACGAGGTCCTCTCAGAAACAGCAAGGATAAATGAGAAGATAAAGGAGATAATAGA
TGAGCACAGCGAACCATGGGGCATAAACGTAACAACGGTGGAGATAAAGGATATAAAACTTCCTGAGGGGATGCAGCGGG
CCATGGCCAGACAGGCAGAGGCTGAAAGAGACAAACGTGCCAAGATAATCACTGCCGAGGGGGAGTACTTCTCAGCAGCA
AAGCTAGGAGAGGCCGCTGATGTGATTGAAAAACATCCGGTGGCCCTTCAACTGAGAAATCTGCAGGTACTGGCTGAAAT
AGCCACAGAAAAGAATTCAACGATAGTATTCCCGGCCCAGTTCATGTCATCCATAAGGGACGTGAAGGAATTCATTGAGA
GGGAGGATGAGTAA

Upstream 100 bases:

>100_bases
GAAACAGCAGGGCAATTTCCTTGGCTCTTATGAGCTTCCAGTAATCCATGTCAATCCCATTATGAGGTTGATCTGACTGC
TGAAAATACTTTACCTTTTC

Downstream 100 bases:

>100_bases
TTGTTTTTCTCAAAGAGAGCGGGAGGTGATACCATGGGAATGCCTTTCCAGCTGTTGTGAAATGTACGAAGAGCGTTGAA
GTTGATATGGATTGAGAAGA

Product: stomatin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MAFSFTLTVNFSILPYYEGQVPHRNLDMGAGPDKHTERWGEVHMDILTAGLLAAVIIVIISLSLKIVKQYERGVVFRLGK
VIGVREPGLRIIIPIIDRMVRVSLRIVTMPIPSQKIITQDNVSIDVAAVAYFKVADPLRAVVAIEDYYGAVNQISQTTVR
NVIGQFVLDEVLSETARINEKIKEIIDEHSEPWGINVTTVEIKDIKLPEGMQRAMARQAEAERDKRAKIITAEGEYFSAA
KLGEAADVIEKHPVALQLRNLQVLAEIATEKNSTIVFPAQFMSSIRDVKEFIEREDE

Sequences:

>Translated_297_residues
MAFSFTLTVNFSILPYYEGQVPHRNLDMGAGPDKHTERWGEVHMDILTAGLLAAVIIVIISLSLKIVKQYERGVVFRLGK
VIGVREPGLRIIIPIIDRMVRVSLRIVTMPIPSQKIITQDNVSIDVAAVAYFKVADPLRAVVAIEDYYGAVNQISQTTVR
NVIGQFVLDEVLSETARINEKIKEIIDEHSEPWGINVTTVEIKDIKLPEGMQRAMARQAEAERDKRAKIITAEGEYFSAA
KLGEAADVIEKHPVALQLRNLQVLAEIATEKNSTIVFPAQFMSSIRDVKEFIEREDE
>Mature_296_residues
AFSFTLTVNFSILPYYEGQVPHRNLDMGAGPDKHTERWGEVHMDILTAGLLAAVIIVIISLSLKIVKQYERGVVFRLGKV
IGVREPGLRIIIPIIDRMVRVSLRIVTMPIPSQKIITQDNVSIDVAAVAYFKVADPLRAVVAIEDYYGAVNQISQTTVRN
VIGQFVLDEVLSETARINEKIKEIIDEHSEPWGINVTTVEIKDIKLPEGMQRAMARQAEAERDKRAKIITAEGEYFSAAK
LGEAADVIEKHPVALQLRNLQVLAEIATEKNSTIVFPAQFMSSIRDVKEFIEREDE

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI21686995, Length=248, Percent_Identity=42.741935483871, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI221316744, Length=248, Percent_Identity=42.741935483871, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI38016911, Length=250, Percent_Identity=43.2, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI7657615, Length=224, Percent_Identity=34.8214285714286, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI7305503, Length=180, Percent_Identity=38.8888888888889, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI20149563, Length=197, Percent_Identity=28.4263959390863, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1786697, Length=185, Percent_Identity=36.7567567567568, Blast_Score=130, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17569493, Length=252, Percent_Identity=42.8571428571429, Blast_Score=201, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI193209764, Length=252, Percent_Identity=42.8571428571429, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17570459, Length=265, Percent_Identity=41.1320754716981, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193210507, Length=221, Percent_Identity=46.606334841629, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17570161, Length=221, Percent_Identity=46.606334841629, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI25153583, Length=237, Percent_Identity=42.6160337552743, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71987612, Length=237, Percent_Identity=42.6160337552743, Blast_Score=184, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71987621, Length=237, Percent_Identity=42.6160337552743, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17569497, Length=235, Percent_Identity=39.5744680851064, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17569499, Length=219, Percent_Identity=44.7488584474886, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71989948, Length=219, Percent_Identity=42.9223744292237, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI32566490, Length=260, Percent_Identity=39.2307692307692, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71989955, Length=156, Percent_Identity=41.6666666666667, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32564147, Length=175, Percent_Identity=42.2857142857143, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71989963, Length=115, Percent_Identity=41.7391304347826, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17542664, Length=195, Percent_Identity=27.6923076923077, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI18860517, Length=265, Percent_Identity=43.7735849056604, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI45556022, Length=264, Percent_Identity=39.7727272727273, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281365664, Length=234, Percent_Identity=44.4444444444444, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24657857, Length=234, Percent_Identity=44.4444444444444, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI62484448, Length=234, Percent_Identity=44.4444444444444, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI62484274, Length=234, Percent_Identity=44.4444444444444, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356845, Length=219, Percent_Identity=35.6164383561644, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281361631, Length=220, Percent_Identity=37.2727272727273, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI281361633, Length=220, Percent_Identity=37.2727272727273, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI28573263, Length=269, Percent_Identity=33.8289962825279, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI45550506, Length=176, Percent_Identity=38.6363636363636, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281361635, Length=165, Percent_Identity=37.5757575757576, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33278; Mature: 33147

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSFTLTVNFSILPYYEGQVPHRNLDMGAGPDKHTERWGEVHMDILTAGLLAAVIIVII
CEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSLKIVKQYERGVVFRLGKVIGVREPGLRIIIPIIDRMVRVSLRIVTMPIPSQKIITQD
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHEEEEEECCCCCCEEECC
NVSIDVAAVAYFKVADPLRAVVAIEDYYGAVNQISQTTVRNVIGQFVLDEVLSETARINE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIKEIIDEHSEPWGINVTTVEIKDIKLPEGMQRAMARQAEAERDKRAKIITAEGEYFSAA
HHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCEEHHH
KLGEAADVIEKHPVALQLRNLQVLAEIATEKNSTIVFPAQFMSSIRDVKEFIEREDE
HCCHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AFSFTLTVNFSILPYYEGQVPHRNLDMGAGPDKHTERWGEVHMDILTAGLLAAVIIVII
EEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSLKIVKQYERGVVFRLGKVIGVREPGLRIIIPIIDRMVRVSLRIVTMPIPSQKIITQD
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHEEEEEECCCCCCEEECC
NVSIDVAAVAYFKVADPLRAVVAIEDYYGAVNQISQTTVRNVIGQFVLDEVLSETARINE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIKEIIDEHSEPWGINVTTVEIKDIKLPEGMQRAMARQAEAERDKRAKIITAEGEYFSAA
HHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCEEHHH
KLGEAADVIEKHPVALQLRNLQVLAEIATEKNSTIVFPAQFMSSIRDVKEFIEREDE
HCCHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]