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Identifier: 15679696

GI number: 15679696

Start: 1557932

End: 1559512

Strand: Direct

Name: Not Available

Synonym: MTH1702

Alternate gene names: 15679696

Gene position: 1557932-1559512 (Clockwise)

Preceding gene: 15679694

Following gene: 15679697

Centisome position: 88.95

GC content: 51.61

Gene sequence:

>1581_bases
TTGAGTACTATGAGGGATAAGCGGAAGGAAATTCTGAAGGAGATCCTCGGGGAATTTGCAGCGGATGAGGAAGAACCACC
CCGTGAGGAAAGGAAGGAGAGGCAGGCGGAATCGGAATTCAAGGTCGAAAAGGTACTTGAGAAGCCCAAGCCAAAACCAG
CCTCTCCACGGGTTGATTTAAAGGACGTTGAGATAATTGAGGGAGACCTCATACCCCAGTACAAGGTTTCCCTTCCCAAG
TTCTCTGAGAAGGAGAGGGAGCTCCTCAATGAGATCCGGGAAAAACTGGTTGAGGTCGCAGTCTCCAAGGGTGAAGAGTT
CAGAATAGATGAATCCACCTTCATGTCTGAGGTTAAGGAGTTCCTCAGGATGAAGGGAGTTCGTAATGTTGACAAACTGG
CAAAGCAGATATCCCAGGAGATGCTGGGGTACGGTGAACTGGACCCCCTAATAAAGGACGATGACCTTGAGGAGATAATG
GTAATAGGTGTCAAAAAACCGGTATTCGTCTACCACAGGAAGCTTGGTATGATGATTACCAATGTCGTCTTCAACAACGA
TGACGACATAAAGGCCATCGTCGACCTCATCGCAAGGCAGGTCAACAGGCGTATAGACCAGCAGACCCCAATACTTGATG
CGAGGCTCCCCGATGGTTCAAGGGTCAATGCAACAATACCCCCGGTTTCTCCAGATGGTTCCACCCTCACCATCCGAAAA
TTCAGGAAGGATCCCTTCACTGTTGTTGACCTCATAAACTTCAAGACCATGTCATCCCACCTTGCAGCCTTCCTCTGGGT
ATGCACAGATGGGCTGGGTGTGAAACCATGCAACGCCATAGTGGCGGGGGGTACCGGGTCCGGTAAAACAACAACCCTGA
ACACAGTATCGGCATTCGTGCCTCCTACTGAGCGTATAATAACCATCGAGGATACCCTGGAGCTTCAGCTACCCCACACC
CATGTACTCAGGATGGAGACAAGGCCGCCCAACATAGAGGGTAAGGGGGAACTTGACATGGACACCCTCGTCAAGAACTC
CCTCCGTCAGAGGCCCGACAGGGTCATTGTGGGGGAGGTGAGGGGCAGTGAGGCCATAACCCTATTCACAGCCCTCAACA
CAGGTCACAGTGGATTCGGGACACTCCACGCCAACACAGCAAGGGAAACCATAACCCGTCTCATAAACCCACCCATGAAT
GTCCCCCGGATCATGATACCGGCCCTGGACTTCATAATAATGCAGAACAGGATGTACAGGCCGGAGGGCGGCTCCATAAG
GAGGATAACTGAGGTCGCCGAGGTCGTGGGTATGGAGGAGGGTAACGTCCAGCTCAACAGGGTCTTTGAGTGGAACAGCG
TGGCTGATAAGGTTGAATATGTTGGTATAGCCAGCCAGACCCTCCGGGAGATAGCGGAACTGAGGGCCATAAGCATAAAT
GAAATCGAGGAGGAAATTGAGAGGAGGAGGCTCGTCCTTGAATACATGGCCGATGAGAATATAAGGAGCATAGATGAGGT
GGGACGTTACATCCATGAATACTACAGGGACCCGGACGGTGTCCTGGACAGCATACTCTGA

Upstream 100 bases:

>100_bases
CCGTAAATATCAACACCGCCCCTGTAGGCAGGGAGGTCCTCCCCACAGACGGGACACCTTGCTGACATACACTTAAATAT
TATCCTCCACATATTAAAGG

Downstream 100 bases:

>100_bases
GGCGTATATAATGGTCTCCATCAGGGATATATTTGACAAACTTGGCGGCATAACACTCACATCCACAAAGAAGGTGGGTG
AGGGTGTCCAGAAGCCGGTT

Product: secretory protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MSTMRDKRKEILKEILGEFAADEEEPPREERKERQAESEFKVEKVLEKPKPKPASPRVDLKDVEIIEGDLIPQYKVSLPK
FSEKERELLNEIREKLVEVAVSKGEEFRIDESTFMSEVKEFLRMKGVRNVDKLAKQISQEMLGYGELDPLIKDDDLEEIM
VIGVKKPVFVYHRKLGMMITNVVFNNDDDIKAIVDLIARQVNRRIDQQTPILDARLPDGSRVNATIPPVSPDGSTLTIRK
FRKDPFTVVDLINFKTMSSHLAAFLWVCTDGLGVKPCNAIVAGGTGSGKTTTLNTVSAFVPPTERIITIEDTLELQLPHT
HVLRMETRPPNIEGKGELDMDTLVKNSLRQRPDRVIVGEVRGSEAITLFTALNTGHSGFGTLHANTARETITRLINPPMN
VPRIMIPALDFIIMQNRMYRPEGGSIRRITEVAEVVGMEEGNVQLNRVFEWNSVADKVEYVGIASQTLREIAELRAISIN
EIEEEIERRRLVLEYMADENIRSIDEVGRYIHEYYRDPDGVLDSIL

Sequences:

>Translated_526_residues
MSTMRDKRKEILKEILGEFAADEEEPPREERKERQAESEFKVEKVLEKPKPKPASPRVDLKDVEIIEGDLIPQYKVSLPK
FSEKERELLNEIREKLVEVAVSKGEEFRIDESTFMSEVKEFLRMKGVRNVDKLAKQISQEMLGYGELDPLIKDDDLEEIM
VIGVKKPVFVYHRKLGMMITNVVFNNDDDIKAIVDLIARQVNRRIDQQTPILDARLPDGSRVNATIPPVSPDGSTLTIRK
FRKDPFTVVDLINFKTMSSHLAAFLWVCTDGLGVKPCNAIVAGGTGSGKTTTLNTVSAFVPPTERIITIEDTLELQLPHT
HVLRMETRPPNIEGKGELDMDTLVKNSLRQRPDRVIVGEVRGSEAITLFTALNTGHSGFGTLHANTARETITRLINPPMN
VPRIMIPALDFIIMQNRMYRPEGGSIRRITEVAEVVGMEEGNVQLNRVFEWNSVADKVEYVGIASQTLREIAELRAISIN
EIEEEIERRRLVLEYMADENIRSIDEVGRYIHEYYRDPDGVLDSIL
>Mature_525_residues
STMRDKRKEILKEILGEFAADEEEPPREERKERQAESEFKVEKVLEKPKPKPASPRVDLKDVEIIEGDLIPQYKVSLPKF
SEKERELLNEIREKLVEVAVSKGEEFRIDESTFMSEVKEFLRMKGVRNVDKLAKQISQEMLGYGELDPLIKDDDLEEIMV
IGVKKPVFVYHRKLGMMITNVVFNNDDDIKAIVDLIARQVNRRIDQQTPILDARLPDGSRVNATIPPVSPDGSTLTIRKF
RKDPFTVVDLINFKTMSSHLAAFLWVCTDGLGVKPCNAIVAGGTGSGKTTTLNTVSAFVPPTERIITIEDTLELQLPHTH
VLRMETRPPNIEGKGELDMDTLVKNSLRQRPDRVIVGEVRGSEAITLFTALNTGHSGFGTLHANTARETITRLINPPMNV
PRIMIPALDFIIMQNRMYRPEGGSIRRITEVAEVVGMEEGNVQLNRVFEWNSVADKVEYVGIASQTLREIAELRAISINE
IEEEIERRRLVLEYMADENIRSIDEVGRYIHEYYRDPDGVLDSIL

Specific function: Involved In A General Secretion Pathway (Gsp) For The Export Of Proteins (By Similarity). [C]

COG id: COG4962

COG function: function code U; Flp pilus assembly protein, ATPase CpaF

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=164, Percent_Identity=34.1463414634146, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011451
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR006141
- InterPro:   IPR001482 [H]

Pfam domain/function: PF07591 DUF1557; PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 59744; Mature: 59612

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00227 TUBULIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMRDKRKEILKEILGEFAADEEEPPREERKERQAESEFKVEKVLEKPKPKPASPRVDL
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KDVEIIEGDLIPQYKVSLPKFSEKERELLNEIREKLVEVAVSKGEEFRIDESTFMSEVKE
CCCCEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHH
FLRMKGVRNVDKLAKQISQEMLGYGELDPLIKDDDLEEIMVIGVKKPVFVYHRKLGMMIT
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHH
NVVFNNDDDIKAIVDLIARQVNRRIDQQTPILDARLPDGSRVNATIPPVSPDGSTLTIRK
HHEECCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEECCCCCCCCCEEEEEE
FRKDPFTVVDLINFKTMSSHLAAFLWVCTDGLGVKPCNAIVAGGTGSGKTTTLNTVSAFV
CCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEHHHCCC
PPTERIITIEDTLELQLPHTHVLRMETRPPNIEGKGELDMDTLVKNSLRQRPDRVIVGEV
CCCCEEEEEECCEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEE
RGSEAITLFTALNTGHSGFGTLHANTARETITRLINPPMNVPRIMIPALDFIIMQNRMYR
CCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PEGGSIRRITEVAEVVGMEEGNVQLNRVFEWNSVADKVEYVGIASQTLREIAELRAISIN
CCCCCHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
EIEEEIERRRLVLEYMADENIRSIDEVGRYIHEYYRDPDGVLDSIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure 
STMRDKRKEILKEILGEFAADEEEPPREERKERQAESEFKVEKVLEKPKPKPASPRVDL
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KDVEIIEGDLIPQYKVSLPKFSEKERELLNEIREKLVEVAVSKGEEFRIDESTFMSEVKE
CCCCEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHH
FLRMKGVRNVDKLAKQISQEMLGYGELDPLIKDDDLEEIMVIGVKKPVFVYHRKLGMMIT
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHH
NVVFNNDDDIKAIVDLIARQVNRRIDQQTPILDARLPDGSRVNATIPPVSPDGSTLTIRK
HHEECCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEEECCCCCCCCCEEEEEE
FRKDPFTVVDLINFKTMSSHLAAFLWVCTDGLGVKPCNAIVAGGTGSGKTTTLNTVSAFV
CCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEHHHCCC
PPTERIITIEDTLELQLPHTHVLRMETRPPNIEGKGELDMDTLVKNSLRQRPDRVIVGEV
CCCCEEEEEECCEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEE
RGSEAITLFTALNTGHSGFGTLHANTARETITRLINPPMNVPRIMIPALDFIIMQNRMYR
CCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PEGGSIRRITEVAEVVGMEEGNVQLNRVFEWNSVADKVEYVGIASQTLREIAELRAISIN
CCCCCHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
EIEEEIERRRLVLEYMADENIRSIDEVGRYIHEYYRDPDGVLDSIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]