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Identifier: 15679555

GI number: 15679555

Start: 1425375

End: 1426688

Strand: Direct

Name: Not Available

Synonym: MTH1559

Alternate gene names: 15679555

Gene position: 1425375-1426688 (Clockwise)

Preceding gene: 15679554

Following gene: 15679556

Centisome position: 81.39

GC content: 51.9

Gene sequence:

>1314_bases
TTGGAGGTAATTATCATGGAATATGTGAAAAATGTGGTCTGCCCCTTCTGCGGAACCCTCTGTGACGACATCATATGTAA
GGTTGAGGGCAACGAGATCGTTGGAACCATCAACGCATGCAGGATAGGTCACAGTAAGTTCGTGCATGCAGAGGGTGCAA
TGAGGTACACCAAACCACTCATAAGAAAGAACGGAGAATTCGTCGAGGTTAGTTACGACGAGGCCATAGACAAGGCAGCA
AAGATTCTTGCAGAATCAAAAAGACCATTAATGTATGGTTGGAGCTGTACCGAGTGCGAGGCACAGGCCGTCGGGGTTGA
ACTTGCAGAGGAGGCCGGTGCAGTAATCGACAACACAGCATCAGTATGCCATGGACCATCAGTCCTCGCCCTCCAGGACG
TGGGTTACCCAATCTGTACCTTCGGTGAGGTCAAAAACAGGGCAGATGTTGTGGTATACTTGGGATGCAACCCGATGCAC
GCCCACCCCAGGCACATGTCAAGGAACGTCTTCGCCCGCGGATTCTTCAGGGAAAGGGGAAGATCAGACAGGACACTCAT
AGTGGTGGATCCAAGGAAAACTGACAGTGCAAAGCTTGCAGACATACACCTGCAGCTCGACTTTGACCATGACTATGAAC
TCCTCGATGCAATGAGGTCATGCCTGCTTGGACATGAGATACTCTACGATGAGGTGGCAGGTGTTCCAAGGGAACAGATC
GAGGAGGCAGTTGAGGTACTCAAAAACGCACAGTTCGGTATACTCTTCTTCGGTATGGGTATAACCCACAGCAGGGGTAA
GCACAGGAACATCGACACAGCCATTATGATGGTGCAGGACCTCAACGACTACGCCAAGTGGACACTCATACCCATGAGGG
GTCACTACAACGTTACAGGGTTCAACCAGGTCTGCACCTGGGAGAGCGGATACCCCTTCTGTGTTGACTTCTCAGAGGGC
GAACCCAGGTACAACCCTGGTGAGACAGGTGCAAACGACCTTCTCCAGAACAGGGAAGCTGACTCCATGATGGTGATAGC
CTCTGACCCGGGAGCCCACTTCCCGCAGAGGGCCCTTGAGAGGATGGCTGAAATCCCTGTGATTGCCATTGAACCCCACA
GGACCCCAACAACCGAGATGGCTGATATCATAATTCCACCGGCCATCGTGGGTATGGAGGCAGAGGGTACCGCCTACCGT
ATGGAGGGTGTCCCTATAAGGATGAAGAAGGTCGTTGACACAGACCTCCTCTCAGACAGGGAGATCCTCGAGAAACTTCT
TGAGAAGGTAAGGGAGTATAAGGCCTCTAAGTAG

Upstream 100 bases:

>100_bases
AGCATACTACAAGTTTGAAGGAGATCACGCAATTAAAGGAGCTAAGGGTATGGTCTATGCGGCTGTCGGATGCAACGGCC
ACATAGAACCCTAAACTTTC

Downstream 100 bases:

>100_bases
GTCCGATCCTAAATAAATTCTATTTTTCCCATTTTCTTCTCATGAAAACTGTTCAGTTTTTGCTTTTTTGTTCTTTATTT
TAACCATTTACCAAAAAATT

Product: tungsten formylmethanofuran dehydrogenase, subunit B

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit B [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MEVIIMEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYTKPLIRKNGEFVEVSYDEAIDKAA
KILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTASVCHGPSVLALQDVGYPICTFGEVKNRADVVVYLGCNPMH
AHPRHMSRNVFARGFFRERGRSDRTLIVVDPRKTDSAKLADIHLQLDFDHDYELLDAMRSCLLGHEILYDEVAGVPREQI
EEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTGFNQVCTWESGYPFCVDFSEG
EPRYNPGETGANDLLQNREADSMMVIASDPGAHFPQRALERMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYR
MEGVPIRMKKVVDTDLLSDREILEKLLEKVREYKASK

Sequences:

>Translated_437_residues
MEVIIMEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYTKPLIRKNGEFVEVSYDEAIDKAA
KILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTASVCHGPSVLALQDVGYPICTFGEVKNRADVVVYLGCNPMH
AHPRHMSRNVFARGFFRERGRSDRTLIVVDPRKTDSAKLADIHLQLDFDHDYELLDAMRSCLLGHEILYDEVAGVPREQI
EEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTGFNQVCTWESGYPFCVDFSEG
EPRYNPGETGANDLLQNREADSMMVIASDPGAHFPQRALERMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYR
MEGVPIRMKKVVDTDLLSDREILEKLLEKVREYKASK
>Mature_437_residues
MEVIIMEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYTKPLIRKNGEFVEVSYDEAIDKAA
KILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTASVCHGPSVLALQDVGYPICTFGEVKNRADVVVYLGCNPMH
AHPRHMSRNVFARGFFRERGRSDRTLIVVDPRKTDSAKLADIHLQLDFDHDYELLDAMRSCLLGHEILYDEVAGVPREQI
EEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTGFNQVCTWESGYPFCVDFSEG
EPRYNPGETGANDLLQNREADSMMVIASDPGAHFPQRALERMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYR
MEGVPIRMKKVVDTDLLSDREILEKLLEKVREYKASK

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile [H]

COG id: COG1029

COG function: function code C; Formylmethanofuran dehydrogenase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdB family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=499, Percent_Identity=25.4509018036072, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI3868719, Length=199, Percent_Identity=27.6381909547739, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI3868720, Length=202, Percent_Identity=26.2376237623762, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016457
- InterPro:   IPR006656 [H]

Pfam domain/function: PF00384 Molybdopterin [H]

EC number: =1.2.99.5 [H]

Molecular weight: Translated: 48891; Mature: 48891

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVIIMEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYTKPL
CEEEHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEHHHEECCCCEEEECCCCHHHHHHH
IRKNGEFVEVSYDEAIDKAAKILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTA
HHCCCCEEEEEHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHCCCEECCCH
SVCHGPSVLALQDVGYPICTFGEVKNRADVVVYLGCNPMHAHPRHMSRNVFARGFFRERG
HHHCCCCEEEECCCCCCEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCC
RSDRTLIVVDPRKTDSAKLADIHLQLDFDHDYELLDAMRSCLLGHEILYDEVAGVPREQI
CCCCEEEEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTG
HHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHEEHEEHHCCCCCEEEEEEECCCCCCCC
FNQVCTWESGYPFCVDFSEGEPRYNPGETGANDLLQNREADSMMVIASDPGAHFPQRALE
CCCEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
RMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYRMEGVPIRMKKVVDTDLLSDR
HHHHCCEEEECCCCCCCHHHHHEECCCHHEEECCCCCEEEECCCCEEHHHHHHHHHCCCH
EILEKLLEKVREYKASK
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEVIIMEYVKNVVCPFCGTLCDDIICKVEGNEIVGTINACRIGHSKFVHAEGAMRYTKPL
CEEEHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEHHHEECCCCEEEECCCCHHHHHHH
IRKNGEFVEVSYDEAIDKAAKILAESKRPLMYGWSCTECEAQAVGVELAEEAGAVIDNTA
HHCCCCEEEEEHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHCCCEECCCH
SVCHGPSVLALQDVGYPICTFGEVKNRADVVVYLGCNPMHAHPRHMSRNVFARGFFRERG
HHHCCCCEEEECCCCCCEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCC
RSDRTLIVVDPRKTDSAKLADIHLQLDFDHDYELLDAMRSCLLGHEILYDEVAGVPREQI
CCCCEEEEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EEAVEVLKNAQFGILFFGMGITHSRGKHRNIDTAIMMVQDLNDYAKWTLIPMRGHYNVTG
HHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHEEHEEHHCCCCCEEEEEEECCCCCCCC
FNQVCTWESGYPFCVDFSEGEPRYNPGETGANDLLQNREADSMMVIASDPGAHFPQRALE
CCCEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
RMAEIPVIAIEPHRTPTTEMADIIIPPAIVGMEAEGTAYRMEGVPIRMKKVVDTDLLSDR
HHHHCCEEEECCCCCCCHHHHHEECCCHHEEECCCCCEEEECCCCEEHHHHHHHHHCCCH
EILEKLLEKVREYKASK
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]