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Identifier: 15679522

GI number: 15679522

Start: 1385729

End: 1387117

Strand: Direct

Name: Not Available

Synonym: MTH1525

Alternate gene names: NA

Gene position: 1385729-1387117 (Clockwise)

Preceding gene: 15679521

Following gene: 15679523

Centisome position: 79.12

GC content: 53.78

Gene sequence:

>1389_bases
ATGAAAGGATCAGTGAGAGGTTGGATAATGGATATAGAGGGATTTGTAAGGCGAAACATGGATTCCATGGATGAGGAGTC
ACTCAGGAACGCACTGGCTGACCTTATACTGGAATTCAAGGATACAGACAGGGAAACATCCATCCGGATGGCGGACGCGG
TTATCTATGAGGTTAAGAATACCCTTAAAACCGGTGGACTCGACGATGGCCTCAGGACCATAATATCATACCCCCCTGCA
GGGGTTGGAATGGGTGAGATGGGGGTCGGGTCCCGGGGTGAGGGCGACTTTTTTGTCCACAGGAAGATCGCAGATATCGT
TTCAAGCACAGGGACACGTTCATTCATAAATCCTGAGGCACAGGATGATGGTGGCGTCGTAAGGACTGAAACAGGAAGTG
GGGACGTATACATAACAACCGCAGTGGACGGGATACACTCACGCCTAAGCGAATACCCCTTCCTCGGGGGCTTCCATGTC
ACCAGGGCAGCCCTGAGGGATGTGTGTGTGATGGGTTCAAGGCCCGTGGCCCTCATAAGCGACCTCCACCTTGCAGATGA
TGGTGACGTCGGTAAACTATTTGACTTCACTGCAGGGGTTGCAGCAGTATCAGAGCTCGTTGGCGTCCCGGTGGTCGCCG
GGAGCACCCTGAGGGTCGGGGGTGACATGGTCCTTGGTGACAGGCTTGTCAGCGCAGTCGGGGCCATAGGCTTTTCAGAG
ACACCACCAACAGCCAGGAAGCGTGCAGAGCCCGGAGACGTCATACTCCTAACAGAGGGGTCAGGAGGCGGGACAATAAC
CACAACCGCCATATACCATGGACTCTTCGATGTTGTATGGGAGACCCTTGACGTGAATTTCATAAGGGCCTCCGAGGCCA
TAATGGATTCAGGGCTCCTGGGCGATGTCCATGCAATGACAGACGTTACAAATGGTGGTCTGAGGGGAGATGCACATGAG
ATATCCTCAACAGCAGGGGTTGGACTGGAATTCGATGCCGATGCGGTCATGTCCATGATAAACCCCAGTGTCCTGAGGAT
GCTGCAGGACCTTGAAATTGACCCCCTCGGCGTCTCCATAGATTCGCTCATGATAATAGCCCCCGAGGACGTGGCCCCTG
ATGTTATGGATACCATAAGGGGTGCAGGCGTTGATGTTGCAGAAATAGGAAGGGTAACTGACTCAGGGGTCCCGGTTCTC
CTGAGGGACGGTTCAGAGGAGGAACTCAGGCCACTCTTCCGTGAGGCAGCATACACCCAGATAAAGAAGATGGTGGGTGA
TAAAACACCCCAGGACTTTGAGGAGATGAAGAGGAAGGTTGAGGATGCTGCAAGGCGTGCCATAGAGAAGAAGGACATGG
TGGTCCGGATGATCTCCCGGGAGGATTAG

Upstream 100 bases:

>100_bases
CCATCGAATCCGATAACATCCATGCAACCCAGTTCCACCCTGAAAAGAGCGGGGAAGCCGGACTGGATGTTCTAAGGAAC
TTTGTCGAAATAATCAGGGC

Downstream 100 bases:

>100_bases
ATCAGGAGAAAGGACAGCCTTCTTGAAGGGATATCATGGATGATGGGGGCTACATATCCACAACCGACGCGGTTCTTGCA
CTCACAGTGGTCTTCATAGT

Product: hydrogenase expression/formation protein HypE related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MKGSVRGWIMDIEGFVRRNMDSMDEESLRNALADLILEFKDTDRETSIRMADAVIYEVKNTLKTGGLDDGLRTIISYPPA
GVGMGEMGVGSRGEGDFFVHRKIADIVSSTGTRSFINPEAQDDGGVVRTETGSGDVYITTAVDGIHSRLSEYPFLGGFHV
TRAALRDVCVMGSRPVALISDLHLADDGDVGKLFDFTAGVAAVSELVGVPVVAGSTLRVGGDMVLGDRLVSAVGAIGFSE
TPPTARKRAEPGDVILLTEGSGGGTITTTAIYHGLFDVVWETLDVNFIRASEAIMDSGLLGDVHAMTDVTNGGLRGDAHE
ISSTAGVGLEFDADAVMSMINPSVLRMLQDLEIDPLGVSIDSLMIIAPEDVAPDVMDTIRGAGVDVAEIGRVTDSGVPVL
LRDGSEEELRPLFREAAYTQIKKMVGDKTPQDFEEMKRKVEDAARRAIEKKDMVVRMISRED

Sequences:

>Translated_462_residues
MKGSVRGWIMDIEGFVRRNMDSMDEESLRNALADLILEFKDTDRETSIRMADAVIYEVKNTLKTGGLDDGLRTIISYPPA
GVGMGEMGVGSRGEGDFFVHRKIADIVSSTGTRSFINPEAQDDGGVVRTETGSGDVYITTAVDGIHSRLSEYPFLGGFHV
TRAALRDVCVMGSRPVALISDLHLADDGDVGKLFDFTAGVAAVSELVGVPVVAGSTLRVGGDMVLGDRLVSAVGAIGFSE
TPPTARKRAEPGDVILLTEGSGGGTITTTAIYHGLFDVVWETLDVNFIRASEAIMDSGLLGDVHAMTDVTNGGLRGDAHE
ISSTAGVGLEFDADAVMSMINPSVLRMLQDLEIDPLGVSIDSLMIIAPEDVAPDVMDTIRGAGVDVAEIGRVTDSGVPVL
LRDGSEEELRPLFREAAYTQIKKMVGDKTPQDFEEMKRKVEDAARRAIEKKDMVVRMISRED
>Mature_462_residues
MKGSVRGWIMDIEGFVRRNMDSMDEESLRNALADLILEFKDTDRETSIRMADAVIYEVKNTLKTGGLDDGLRTIISYPPA
GVGMGEMGVGSRGEGDFFVHRKIADIVSSTGTRSFINPEAQDDGGVVRTETGSGDVYITTAVDGIHSRLSEYPFLGGFHV
TRAALRDVCVMGSRPVALISDLHLADDGDVGKLFDFTAGVAAVSELVGVPVVAGSTLRVGGDMVLGDRLVSAVGAIGFSE
TPPTARKRAEPGDVILLTEGSGGGTITTTAIYHGLFDVVWETLDVNFIRASEAIMDSGLLGDVHAMTDVTNGGLRGDAHE
ISSTAGVGLEFDADAVMSMINPSVLRMLQDLEIDPLGVSIDSLMIIAPEDVAPDVMDTIRGAGVDVAEIGRVTDSGVPVL
LRDGSEEELRPLFREAAYTQIKKMVGDKTPQDFEEMKRKVEDAARRAIEKKDMVVRMISRED

Specific function: Unknown

COG id: COG1973

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR009186
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 49474; Mature: 49474

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSVRGWIMDIEGFVRRNMDSMDEESLRNALADLILEFKDTDRETSIRMADAVIYEVKN
CCCCCCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TLKTGGLDDGLRTIISYPPAGVGMGEMGVGSRGEGDFFVHRKIADIVSSTGTRSFINPEA
HHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCC
QDDGGVVRTETGSGDVYITTAVDGIHSRLSEYPFLGGFHVTRAALRDVCVMGSRPVALIS
CCCCCEEEEECCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHE
DLHLADDGDVGKLFDFTAGVAAVSELVGVPVVAGSTLRVGGDMVLGDRLVSAVGAIGFSE
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCHHHHHHHHHHHHCCCCC
TPPTARKRAEPGDVILLTEGSGGGTITTTAIYHGLFDVVWETLDVNFIRASEAIMDSGLL
CCCHHHHCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCC
GDVHAMTDVTNGGLRGDAHEISSTAGVGLEFDADAVMSMINPSVLRMLQDLEIDPLGVSI
CCHHHHHHCCCCCCCCCHHHHHHHCCCCEEECHHHHHHHHCHHHHHHHHHCCCCCCCCCC
DSLMIIAPEDVAPDVMDTIRGAGVDVAEIGRVTDSGVPVLLRDGSEEELRPLFREAAYTQ
CCEEEECCCCCCCHHHHHHHCCCCCHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
IKKMVGDKTPQDFEEMKRKVEDAARRAIEKKDMVVRMISRED
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKGSVRGWIMDIEGFVRRNMDSMDEESLRNALADLILEFKDTDRETSIRMADAVIYEVKN
CCCCCCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TLKTGGLDDGLRTIISYPPAGVGMGEMGVGSRGEGDFFVHRKIADIVSSTGTRSFINPEA
HHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCC
QDDGGVVRTETGSGDVYITTAVDGIHSRLSEYPFLGGFHVTRAALRDVCVMGSRPVALIS
CCCCCEEEEECCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHE
DLHLADDGDVGKLFDFTAGVAAVSELVGVPVVAGSTLRVGGDMVLGDRLVSAVGAIGFSE
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCHHHHHHHHHHHHCCCCC
TPPTARKRAEPGDVILLTEGSGGGTITTTAIYHGLFDVVWETLDVNFIRASEAIMDSGLL
CCCHHHHCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCC
GDVHAMTDVTNGGLRGDAHEISSTAGVGLEFDADAVMSMINPSVLRMLQDLEIDPLGVSI
CCHHHHHHCCCCCCCCCHHHHHHHCCCCEEECHHHHHHHHCHHHHHHHHHCCCCCCCCCC
DSLMIIAPEDVAPDVMDTIRGAGVDVAEIGRVTDSGVPVLLRDGSEEELRPLFREAAYTQ
CCEEEECCCCCCCHHHHHHHCCCCCHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
IKKMVGDKTPQDFEEMKRKVEDAARRAIEKKDMVVRMISRED
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]